Gene description for RAB7A
Gene name RAB7A, member RAS oncogene family
Gene symbol RAB7A
Other names/aliases PRO2706
RAB7
Species Homo sapiens
 Database cross references - RAB7A
ExoCarta ExoCarta_7879
Vesiclepedia VP_7879
Entrez Gene 7879
HGNC 9788
MIM 602298
UniProt P51149  
 RAB7A identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 15326289    
Urine 19056867    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for RAB7A
Molecular Function
    GTPase activity GO:0003924 IDA
    G protein activity GO:0003925 IEA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IDA
    GDP binding GO:0019003 IDA
    small GTPase binding GO:0031267 IEA
    retromer complex binding GO:1905394 IMP
Biological Process
    autophagosome assembly GO:0000045 IMP
    protein targeting to lysosome GO:0006622 IMP
    endocytosis GO:0006897 TAS
    epidermal growth factor catabolic process GO:0007174 IMP
    endosome to lysosome transport GO:0008333 IBA
    endosome to lysosome transport GO:0008333 IMP
    response to bacterium GO:0009617 IMP
    protein transport GO:0015031 TAS
    lipid catabolic process GO:0016042 IEA
    viral release from host cell GO:0019076 IMP
    protein to membrane docking GO:0022615 IDA
    synaptic vesicle recycling via endosome GO:0036466 IEA
    retrograde transport, endosome to Golgi GO:0042147 IMP
    early endosome to late endosome transport GO:0045022 IMP
    bone resorption GO:0045453 IEA
    positive regulation of protein catabolic process GO:0045732 IMP
    intracellular transport GO:0046907 IMP
    positive regulation of viral process GO:0048524 IMP
    establishment of vesicle localization GO:0051650 IEA
    lipophagy GO:0061724 ISS
    phagosome maturation GO:0090382 TAS
    phagosome acidification GO:0090383 IMP
    phagosome-lysosome fusion GO:0090385 IBA
    phagosome-lysosome fusion GO:0090385 IMP
    neurotransmitter receptor transport, postsynaptic endosome to lysosome GO:0098943 IEA
    endosome to plasma membrane protein transport GO:0099638 IMP
    negative regulation of exosomal secretion GO:1903542 IMP
    positive regulation of exosomal secretion GO:1903543 IMP
    negative regulation of intralumenal vesicle formation GO:1905366 TAS
Subcellular Localization
    autophagosome membrane GO:0000421 IEA
    mitochondrion GO:0005739 IDA
    lysosome GO:0005764 IDA
    lysosome GO:0005764 IDA
    lysosomal membrane GO:0005765 TAS
    late endosome GO:0005770 IDA
    late endosome GO:0005770 IDA
    Golgi apparatus GO:0005794 IEA
    lipid droplet GO:0005811 ISS
    cytosol GO:0005829 ISS
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 TAS
    endosome membrane GO:0010008 IDA
    endosome membrane GO:0010008 IMP
    secretory granule membrane GO:0030667 TAS
    phagocytic vesicle membrane GO:0030670 TAS
    synaptic vesicle membrane GO:0030672 IEA
    retromer complex GO:0030904 IDA
    late endosome membrane GO:0031902 ISS
    mitochondrial membrane GO:0031966 IEA
    melanosome membrane GO:0033162 IEA
    phagophore assembly site membrane GO:0034045 IEA
    phagocytic vesicle GO:0045335 IBA
    phagocytic vesicle GO:0045335 IDA
    extracellular exosome GO:0070062 HDA
    alveolar lamellar body GO:0097208 IEA
    presynaptic endosome GO:0098830 IEA
    glutamatergic synapse GO:0098978 IEA
 Experiment description of studies that identified RAB7A in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
18
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
19
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
24
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
25
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
26
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
27
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
28
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
40
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 200
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
46
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
49
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
51
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
52
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
54
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
56
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
58
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
59
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
60
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
61
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
62
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
63
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
64
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
65
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
66
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
67
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
68
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
69
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
70
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
71
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
72
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
73
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
74
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
75
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB7A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Proximity Label-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 PEX13  
Proximity Label-MS Homo sapiens
4 WDR91 29062
Proximity Label-MS Homo sapiens
5 MUC13 56667
Affinity Capture-MS Homo sapiens
6 GJD3  
Proximity Label-MS Homo sapiens
7 APPL2 55198
Proximity Label-MS Homo sapiens
8 WDR6 11180
Proximity Label-MS Homo sapiens
9 FAM73A  
Proximity Label-MS Homo sapiens
10 LYST 1130
Proximity Label-MS Homo sapiens
11 UBL4A 8266
Affinity Capture-MS Homo sapiens
12 BCAT2 587
Proximity Label-MS Homo sapiens
13 SEC16A 9919
Proximity Label-MS Homo sapiens
14 MSRB2  
Co-fractionation Homo sapiens
15 EIF3C 8663
Proximity Label-MS Homo sapiens
16 PKM 5315
Co-fractionation Homo sapiens
17 ACOT9 23597
Co-fractionation Homo sapiens
18 ATP13A2  
Co-localization Homo sapiens
19 RAB9A 9367
Proximity Label-MS Homo sapiens
20 FKBP15 23307
Proximity Label-MS Homo sapiens
21 JPH1 56704
Proximity Label-MS Homo sapiens
22 VMP1 81671
Proximity Label-MS Homo sapiens
23 PLEKHM3 389072
Proximity Label-MS Homo sapiens
24 APOE 348
Co-fractionation Homo sapiens
25 VPS13C 54832
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
26 TXNDC12 51060
Co-fractionation Homo sapiens
27 ST7  
Proximity Label-MS Homo sapiens
28 SOX2  
Affinity Capture-MS Homo sapiens
29 KDELR1 10945
Proximity Label-MS Homo sapiens
30 ANKRD50 57182
Proximity Label-MS Homo sapiens
31 C16orf62 57020
Proximity Label-MS Homo sapiens
32 RHEB 6009
Co-localization Homo sapiens
Co-fractionation Homo sapiens
33 MCU 90550
Affinity Capture-MS Homo sapiens
34 MON2 23041
Proximity Label-MS Homo sapiens
35 OSBPL9 114883
Proximity Label-MS Homo sapiens
36 COX7A2L 9167
Co-fractionation Homo sapiens
37 DGKE  
Proximity Label-MS Homo sapiens
38 RAI14 26064
Proximity Label-MS Homo sapiens
39 GDI1 2664
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 Fgfr1op  
Affinity Capture-MS Mus musculus
41 ABCD3 5825
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
42 FBL 2091
Proximity Label-MS Homo sapiens
43 ARMCX3 51566
Proximity Label-MS Homo sapiens
44 TMEM201 199953
Proximity Label-MS Homo sapiens
45 CHMP2B 25978
Affinity Capture-MS Homo sapiens
46 SCAP  
Proximity Label-MS Homo sapiens
47 LAMTOR3 8649
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
48 OCLN 100506658
Proximity Label-MS Homo sapiens
49 USP33  
Proximity Label-MS Homo sapiens
50 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
51 UCHL5 51377
Reconstituted Complex Homo sapiens
52 GTSE1 51512
Affinity Capture-MS Homo sapiens
53 C18orf8 29919
Proximity Label-MS Homo sapiens
54 MECP2 4204
Affinity Capture-MS Homo sapiens
55 ARFGEF2 10564
Proximity Label-MS Homo sapiens
56 SLC6A15 55117
Proximity Label-MS Homo sapiens
57 ZFYVE9  
Proximity Label-MS Homo sapiens
58 TFRC 7037
Affinity Capture-MS Homo sapiens
59 EEF1A1 1915
Co-fractionation Homo sapiens
60 SLC25A3 5250
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
61 KIF14 9928
Affinity Capture-MS Homo sapiens
62 RNF115  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
63 Vim 22352
Affinity Capture-MS Mus musculus
64 EMC1 23065
Proximity Label-MS Homo sapiens
65 TMEM106C 79022
Proximity Label-MS Homo sapiens
66 KLF16  
Affinity Capture-MS Homo sapiens
67 RAB17 64284
Two-hybrid Homo sapiens
68 MTCH2 23788
Proximity Label-MS Homo sapiens
69 RIN3  
Affinity Capture-MS Homo sapiens
70 RAB14 51552
Affinity Capture-MS Homo sapiens
71 SH3BP4 23677
Proximity Label-MS Homo sapiens
72 PLD1 5337
Proximity Label-MS Homo sapiens
73 ATP7B 540
Proximity Label-MS Homo sapiens
74 MCAM 4162
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
75 PDXDC1 23042
Proximity Label-MS Homo sapiens
76 UBAC2 337867
Affinity Capture-MS Homo sapiens
77 SLC25A20 788
Co-fractionation Homo sapiens
78 UBXN8  
Proximity Label-MS Homo sapiens
79 CLCC1 23155
Proximity Label-MS Homo sapiens
80 RRAGC 64121
Proximity Label-MS Homo sapiens
81 AKAP11 11215
Proximity Label-MS Homo sapiens
82 SAR1B 51128
Proximity Label-MS Homo sapiens
83 GORASP2 26003
Proximity Label-MS Homo sapiens
84 CCZ1B 221960
Proximity Label-MS Homo sapiens
85 C6orf120  
Affinity Capture-MS Homo sapiens
86 PIGS 94005
Proximity Label-MS Homo sapiens
87 RAB4B 53916
Two-hybrid Homo sapiens
88 FLOT2 2319
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
89 GOLGB1 2804
Proximity Label-MS Homo sapiens
90 VDAC2 7417
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
91 SEC61B 10952
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
92 LRCH3 84859
Proximity Label-MS Homo sapiens
93 LRP8 7804
Proximity Label-MS Homo sapiens
94 LRIG3  
Proximity Label-MS Homo sapiens
95 RFFL 117584
Affinity Capture-Western Homo sapiens
96 REEP5 7905
Proximity Label-MS Homo sapiens
97 ANLN 54443
Affinity Capture-MS Homo sapiens
98 TMF1 7110
Proximity Label-MS Homo sapiens
99 DST 667
Proximity Label-MS Homo sapiens
100 MECR 51102
Co-fractionation Homo sapiens
101 RAB6A 5870
Two-hybrid Homo sapiens
102 ANO6 196527
Proximity Label-MS Homo sapiens
103 SV2A 9900
Proximity Label-MS Homo sapiens
104 FAM83B  
Proximity Label-MS Homo sapiens
105 HADHB 3032
Co-fractionation Homo sapiens
106 HADHA 3030
Co-fractionation Homo sapiens
107 NEO1 4756
Proximity Label-MS Homo sapiens
108 VIPAS39 63894
Proximity Label-MS Homo sapiens
109 LRRC59 55379
Proximity Label-MS Homo sapiens
110 CDCA3 83461
Proximity Label-MS Homo sapiens
111 NBEA  
Proximity Label-MS Homo sapiens
112 SCAMP1 9522
Proximity Label-MS Homo sapiens
113 LRCH4  
Proximity Label-MS Homo sapiens
114 TMED8 283578
Proximity Label-MS Homo sapiens
115 TAPT1 202018
Proximity Label-MS Homo sapiens
116 CD274 29126
Affinity Capture-MS Homo sapiens
117 BCAP31 10134
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
118 RAB29 8934
Proximity Label-MS Homo sapiens
119 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
120 GPD2 2820
Proximity Label-MS Homo sapiens
121 FKBP8 23770
Proximity Label-MS Homo sapiens
122 AAAS 8086
Proximity Label-MS Homo sapiens
123 PI4K2A 55361
Proximity Label-MS Homo sapiens
124 FN1 2335
Affinity Capture-MS Homo sapiens
125 CDC42 998
Co-fractionation Homo sapiens
126 CYP51A1 1595
Proximity Label-MS Homo sapiens
127 PVRL2 5819
Proximity Label-MS Homo sapiens
128 ZW10 9183
Proximity Label-MS Homo sapiens
129 MBOAT7 79143
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
130 SOAT1 6646
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
131 IST1 9798
Affinity Capture-MS Homo sapiens
132 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
133 SNX17 9784
Proximity Label-MS Homo sapiens
134 TMCO1 54499
Proximity Label-MS Homo sapiens
135 UHRF1BP1 54887
Proximity Label-MS Homo sapiens
136 DHRS7B 25979
Co-fractionation Homo sapiens
137 DLST 1743
Affinity Capture-MS Homo sapiens
138 SLC30A7 148867
Proximity Label-MS Homo sapiens
139 COG3 83548
Proximity Label-MS Homo sapiens
140 FAM21C 253725
Proximity Label-MS Homo sapiens
141 NDUFA3  
Co-fractionation Homo sapiens
142 ATP6V0A1 535
Affinity Capture-MS Homo sapiens
143 KIDINS220 57498
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
144 SLC35A2  
Proximity Label-MS Homo sapiens
145 EIF4G2 1982
Co-fractionation Homo sapiens
146 PARP16 54956
Proximity Label-MS Homo sapiens
147 PDE8A 5151
Proximity Label-MS Homo sapiens
148 SCCPDH 51097
Co-fractionation Homo sapiens
149 GDAP2 54834
Affinity Capture-MS Homo sapiens
150 SLC4A2 6522
Proximity Label-MS Homo sapiens
151 COA4  
Co-fractionation Homo sapiens
152 SLC38A2 54407
Proximity Label-MS Homo sapiens
153 CHML  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
154 TMEM57  
Proximity Label-MS Homo sapiens
155 TGFBR2 7048
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
156 NSF 4905
Affinity Capture-MS Homo sapiens
157 SSFA2 6744
Affinity Capture-MS Homo sapiens
158 SCYL3 57147
Proximity Label-MS Homo sapiens
159 AGPAT9  
Proximity Label-MS Homo sapiens
160 PIEZO1 9780
Affinity Capture-MS Homo sapiens
161 ZFYVE27 118813
Proximity Label-MS Homo sapiens
162 WWOX 51741
Proximity Label-MS Homo sapiens
163 VAC14 55697
Proximity Label-MS Homo sapiens
164 EMC7 56851
Proximity Label-MS Homo sapiens
165 RTN3 10313
Proximity Label-MS Homo sapiens
166 EMC4 51234
Proximity Label-MS Homo sapiens
167 ACTR10 55860
Proximity Label-MS Homo sapiens
168 APRT 353
Co-fractionation Homo sapiens
169 ITCH 83737
Proximity Label-MS Homo sapiens
170 PIK3R4 30849
Proximity Label-MS Homo sapiens
171 FYCO1 79443
Proximity Label-MS Homo sapiens
172 ITPR3 3710
Proximity Label-MS Homo sapiens
173 C19orf25  
Proximity Label-MS Homo sapiens
174 WDR81 124997
Proximity Label-MS Homo sapiens
175 BLOC1S1  
Proximity Label-MS Homo sapiens
176 TRIP11 9321
Proximity Label-MS Homo sapiens
177 KIAA1033 23325
Proximity Label-MS Homo sapiens
178 FLCN 201163
Proximity Label-MS Homo sapiens
179 VAMP7 6845
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
180 RABL3 285282
Proximity Label-MS Homo sapiens
181 CTDSP2 10106
Proximity Label-MS Homo sapiens
182 RAB2A 5862
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
183 GOLGA5 9950
Proximity Label-MS Homo sapiens
184 PSMA7 5688
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
185 SLC33A1 9197
Proximity Label-MS Homo sapiens
186 RAB11A 8766
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
187 KXD1 79036
Proximity Label-MS Homo sapiens
188 DHFRL1  
Proximity Label-MS Homo sapiens
189 EPHA2 1969
Proximity Label-MS Homo sapiens
190 CISD2 493856
Proximity Label-MS Homo sapiens
191 CUL7 9820
Affinity Capture-MS Homo sapiens
192 RAB5C 5878
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
193 WFS1 7466
Proximity Label-MS Homo sapiens
194 ANXA2 302
Co-fractionation Homo sapiens
195 VANGL1 81839
Proximity Label-MS Homo sapiens
196 SNX29  
Proximity Label-MS Homo sapiens
197 SCAMP3 10067
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
198 ACBD3 64746
Proximity Label-MS Homo sapiens
199 NDUFS6  
Affinity Capture-MS Homo sapiens
200 CTNND1 1500
Proximity Label-MS Homo sapiens
201 DERL1 79139
Proximity Label-MS Homo sapiens
202 TRAPPC2 6399
Proximity Label-MS Homo sapiens
203 PDHA1 5160
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
204 PEX6  
Proximity Label-MS Homo sapiens
205 SRPRB 58477
Proximity Label-MS Homo sapiens
206 OSBPL10  
Proximity Label-MS Homo sapiens
207 RINT1 60561
Proximity Label-MS Homo sapiens
208 METTL7A 25840
Proximity Label-MS Homo sapiens
209 LAMP3  
Proximity Label-MS Homo sapiens
210 CPM 1368
Affinity Capture-MS Homo sapiens
211 APBB2  
Proximity Label-MS Homo sapiens
212 ARL6IP5 10550
Proximity Label-MS Homo sapiens
213 RPA2 6118
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
214 SECISBP2L  
Cross-Linking-MS (XL-MS) Homo sapiens
215 SRPR 6734
Proximity Label-MS Homo sapiens
216 FAM21A 387680
Proximity Label-MS Homo sapiens
217 FMN2  
Proximity Label-MS Homo sapiens
218 VAMP2 6844
Proximity Label-MS Homo sapiens
219 PKMYT1  
Proximity Label-MS Homo sapiens
220 ARL8B 55207
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
221 CPT1A 1374
Affinity Capture-MS Homo sapiens
222 ATP5L 10632
Co-fractionation Homo sapiens
223 ABCD1 215
Affinity Capture-MS Homo sapiens
224 VPS26A 9559
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
225 PPP2R1B 5519
Affinity Capture-MS Homo sapiens
226 PRR11  
Proximity Label-MS Homo sapiens
227 FNIP2  
Proximity Label-MS Homo sapiens
228 OGDH 4967
Co-fractionation Homo sapiens
229 WDR41  
Proximity Label-MS Homo sapiens
230 HSPA2 3306
Co-fractionation Homo sapiens
231 STX8 9482
Proximity Label-MS Homo sapiens
232 CHP1 11261
Proximity Label-MS Homo sapiens
233 GOLGA3 2802
Proximity Label-MS Homo sapiens
234 DIAPH2  
Proximity Label-MS Homo sapiens
235 DSCR3 10311
Proximity Label-MS Homo sapiens
236 TRABD 80305
Proximity Label-MS Homo sapiens
237 NETO2  
Proximity Label-MS Homo sapiens
238 CCDC53 51019
Proximity Label-MS Homo sapiens
239 WDR7 23335
Proximity Label-MS Homo sapiens
240 ARFIP2 23647
Proximity Label-MS Homo sapiens
241 WASH1 100287171
Proximity Label-MS Homo sapiens
242 TOM1 10043
Proximity Label-MS Homo sapiens
243 RAB5B 5869
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
244 SUN2 25777
Proximity Label-MS Homo sapiens
245 TMEM192 201931
Affinity Capture-MS Homo sapiens
246 YIPF3 25844
Proximity Label-MS Homo sapiens
247 FIG4 9896
Proximity Label-MS Homo sapiens
248 PHB 5245
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
249 TOMM40 10452
Affinity Capture-MS Homo sapiens
250 B9D1 27077
Proximity Label-MS Homo sapiens
251 LOH12CR1 118426
Proximity Label-MS Homo sapiens
252 FGFR1 2260
Affinity Capture-MS Homo sapiens
253 RHOG 391
Affinity Capture-MS Homo sapiens
254 RRAGA 10670
Proximity Label-MS Homo sapiens
255 TDRKH  
Proximity Label-MS Homo sapiens
256 LMAN1 3998
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
257 PDZD8 118987
Proximity Label-MS Homo sapiens
258 KIAA1715 80856
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
259 VPS13D 55187
Proximity Label-MS Homo sapiens
260 CALM2 805
Proximity Label-MS Homo sapiens
261 ATP6V1G1 9550
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
262 SPG21 51324
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
263 ATG2A  
Proximity Label-MS Homo sapiens
264 ATF6B  
Proximity Label-MS Homo sapiens
265 NPC1 4864
Proximity Label-MS Homo sapiens
266 VPS45 11311
Proximity Label-MS Homo sapiens
267 STOM 2040
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
268 NDUFA8 4702
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
269 TMEM189-UBE2V1 387522
Co-fractionation Homo sapiens
270 GLE1 2733
Proximity Label-MS Homo sapiens
271 BAG6 7917
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
272 SNAP47 116841
Proximity Label-MS Homo sapiens
273 JAM3 83700
Proximity Label-MS Homo sapiens
274 TMEM43 79188
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
275 RAP1B 5908
Co-fractionation Homo sapiens
276 PMAIP1  
Affinity Capture-MS Homo sapiens
277 SCARB1 949
Proximity Label-MS Homo sapiens
278 TRPM7 54822
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
279 C5orf51 285636
Proximity Label-MS Homo sapiens
280 RAP1A 5906
Co-fractionation Homo sapiens
281 TBC1D5 9779
Proximity Label-MS Homo sapiens
282 MTDH 92140
Proximity Label-MS Homo sapiens
283 GPHN 10243
Proximity Label-MS Homo sapiens
284 RGP1 9827
Proximity Label-MS Homo sapiens
285 PREB 10113
Proximity Label-MS Homo sapiens
286 PTTG1IP 754
Affinity Capture-MS Homo sapiens
287 ATP4A 495
Proximity Label-MS Homo sapiens
288 STX5 6811
Proximity Label-MS Homo sapiens
289 SLC12A4 6560
Proximity Label-MS Homo sapiens
290 AGPS 8540
Co-fractionation Homo sapiens
291 VPS26B 112936
Proximity Label-MS Homo sapiens
292 SLC30A6 55676
Proximity Label-MS Homo sapiens
293 RBSN 64145
Proximity Label-MS Homo sapiens
294 NDC1 55706
Proximity Label-MS Homo sapiens
295 VPS11 55823
Reconstituted Complex Homo sapiens
296 MARVELD2 153562
Proximity Label-MS Homo sapiens
297 GOLGA4  
Proximity Label-MS Homo sapiens
298 SGPL1 8879
Proximity Label-MS Homo sapiens
299 STXBP5 134957
Proximity Label-MS Homo sapiens
300 RPN2 6185
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 FURIN 5045
Proximity Label-MS Homo sapiens
302 SCD5  
Proximity Label-MS Homo sapiens
303 TMPO 7112
Proximity Label-MS Homo sapiens
304 ICAM1 3383
Co-fractionation Homo sapiens
305 EMC8 10328
Proximity Label-MS Homo sapiens
306 RAB5A 5868
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
307 SLC27A4 10999
Proximity Label-MS Homo sapiens
308 BET1 10282
Proximity Label-MS Homo sapiens
309 PRKAA2 5563
Proximity Label-MS Homo sapiens
310 SLC26A2 1836
Proximity Label-MS Homo sapiens
311 DMXL1 1657
Proximity Label-MS Homo sapiens
312 LAMTOR4 389541
Proximity Label-MS Homo sapiens
313 MAVS 57506
Proximity Label-MS Homo sapiens
314 FUS 2521
Affinity Capture-MS Homo sapiens
315 KIAA1524 57650
Affinity Capture-MS Homo sapiens
316 ARFIP1 27236
Proximity Label-MS Homo sapiens
317 AGPAT6 137964
Proximity Label-MS Homo sapiens
318 PCDH7 5099
Proximity Label-MS Homo sapiens
319 WDR24  
Proximity Label-MS Homo sapiens
320 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
321 ATP2A1 487
Proximity Label-MS Homo sapiens
322 FAM134B 54463
Proximity Label-MS Homo sapiens
323 TMOD3 29766
Proximity Label-MS Homo sapiens
324 MTFR1  
Proximity Label-MS Homo sapiens
325 SLC12A7 10723
Proximity Label-MS Homo sapiens
326 VRK2 7444
Proximity Label-MS Homo sapiens
327 DDRGK1 65992
Proximity Label-MS Homo sapiens
328 SLC12A6 9990
Proximity Label-MS Homo sapiens
329 RHOB 388
Proximity Label-MS Homo sapiens
330 TMEM209 84928
Proximity Label-MS Homo sapiens
331 NDUFV2 4729
Affinity Capture-MS Homo sapiens
332 LMNA 4000
Proximity Label-MS Homo sapiens
333 OSBPL8 114882
Proximity Label-MS Homo sapiens
334 MLEC 9761
Affinity Capture-MS Homo sapiens
335 TOMM20 9804
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
336 HUWE1 10075
Affinity Capture-MS Homo sapiens
337 OST4  
Affinity Capture-MS Homo sapiens
338 STX12 23673
Proximity Label-MS Homo sapiens
339 DENND4C 55667
Proximity Label-MS Homo sapiens
340 TMEM87A 25963
Proximity Label-MS Homo sapiens
341 SNX14  
Proximity Label-MS Homo sapiens
342 KIF1A 547
Proximity Label-MS Homo sapiens
343 PRKD3 23683
Proximity Label-MS Homo sapiens
344 NUTF2 10204
Co-fractionation Homo sapiens
345 TRIM13  
Proximity Label-MS Homo sapiens
346 SCFD2 152579
Proximity Label-MS Homo sapiens
347 VPS13B  
Proximity Label-MS Homo sapiens
348 TMEM214 54867
Proximity Label-MS Homo sapiens
349 NOTCH2 4853
Proximity Label-MS Homo sapiens
350 GOSR1 9527
Proximity Label-MS Homo sapiens
351 TACC1 6867
Proximity Label-MS Homo sapiens
352 XPR1 9213
Affinity Capture-MS Homo sapiens
353 LRBA 987
Proximity Label-MS Homo sapiens
354 CAMLG 819
Proximity Label-MS Homo sapiens
355 DNAJC16  
Proximity Label-MS Homo sapiens
356 ABCC4 10257
Proximity Label-MS Homo sapiens
357 PIGU 128869
Proximity Label-MS Homo sapiens
358 TSC1 7248
Proximity Label-MS Homo sapiens
359 ZDHHC13 54503
Proximity Label-MS Homo sapiens
360 NUP155 9631
Proximity Label-MS Homo sapiens
361 MAP2K1 5604
Affinity Capture-MS Homo sapiens
362 HNRNPK 3190
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
363 VPS33A 65082
Proximity Label-MS Homo sapiens
364 AUP1 550
Proximity Label-MS Homo sapiens
365 RAB8A 4218
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
366 GRAMD1A  
Proximity Label-MS Homo sapiens
367 BCL2L13 23786
Proximity Label-MS Homo sapiens
368 DENND4A 10260
Proximity Label-MS Homo sapiens
369 C16orf72 29035
Affinity Capture-MS Homo sapiens
370 YKT6 10652
Proximity Label-MS Homo sapiens
371 IGF2R 3482
Proximity Label-MS Homo sapiens
372 DHRS7 51635
Proximity Label-MS Homo sapiens
373 RPS6KC1  
Proximity Label-MS Homo sapiens
374 KRAS 3845
Proximity Label-MS Homo sapiens
375 CKAP4 10970
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
376 PTRF 284119
Affinity Capture-MS Homo sapiens
377 ANKRD46 157567
Proximity Label-MS Homo sapiens
378 VPS33B 26276
Proximity Label-MS Homo sapiens
379 VPS8 23355
Proximity Label-MS Homo sapiens
380 LRIG1 26018
Proximity Label-MS Homo sapiens
381 C17orf59 54785
Proximity Label-MS Homo sapiens
382 CHMP1A 5119
Affinity Capture-MS Homo sapiens
383 NDUFB4 4710
Affinity Capture-MS Homo sapiens
384 CHMP2A 27243
Affinity Capture-MS Homo sapiens
385 NUPL2 11097
Proximity Label-MS Homo sapiens
386 ATP6V1B2 526
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
387 POMGNT1 55624
Proximity Label-MS Homo sapiens
388 VPS41 27072
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
389 CLCN7 1186
Proximity Label-MS Homo sapiens
390 MTCH1 23787
Proximity Label-MS Homo sapiens
391 KIF16B 55614
Proximity Label-MS Homo sapiens
392 RAB1A 5861
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
393 NDUFS1 4719
Affinity Capture-MS Homo sapiens
394 MARCKS 4082
Proximity Label-MS Homo sapiens
395 SAMM50 25813
Proximity Label-MS Homo sapiens
396 LAP3 51056
Affinity Capture-MS Homo sapiens
397 TMUB1  
Affinity Capture-MS Homo sapiens
398 ADGRL2 23266
Proximity Label-MS Homo sapiens
399 NBAS 51594
Proximity Label-MS Homo sapiens
400 GRIPAP1 56850
Proximity Label-MS Homo sapiens
401 UQCRC1 7384
Affinity Capture-Western Homo sapiens
402 SYNE2 23224
Proximity Label-MS Homo sapiens
403 PTPN1 5770
Proximity Label-MS Homo sapiens
404 APBB1  
Proximity Label-MS Homo sapiens
405 PLEKHM1  
Proximity Label-MS Homo sapiens
406 RTN4 57142
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
407 TMX1 81542
Proximity Label-MS Homo sapiens
408 PI4KA 5297
Proximity Label-MS Homo sapiens
409 LRPPRC 10128
Affinity Capture-MS Homo sapiens
410 CAPZB 832
Affinity Capture-MS Homo sapiens
411 RNF121 55298
Proximity Label-MS Homo sapiens
412 MGST1 4257
Co-fractionation Homo sapiens
413 ANKLE2 23141
Proximity Label-MS Homo sapiens
414 PRKCDBP 112464
Affinity Capture-MS Homo sapiens
415 NDUFB8 4714
Affinity Capture-MS Homo sapiens
416 SDHB 6390
Co-fractionation Homo sapiens
417 RASAL2 9462
Proximity Label-MS Homo sapiens
418 CHMP5 51510
Co-localization Homo sapiens
419 RHBDD2  
Proximity Label-MS Homo sapiens
420 RAB3B 5865
Proximity Label-MS Homo sapiens
421 AK3 50808
Co-fractionation Homo sapiens
422 ATL1 51062
Proximity Label-MS Homo sapiens
423 STK11IP 114790
Proximity Label-MS Homo sapiens
424 CCDC47 57003
Proximity Label-MS Homo sapiens
425 MXRA7 439921
Proximity Label-MS Homo sapiens
426 RAB8B 51762
Co-fractionation Homo sapiens
427 BET1L 51272
Proximity Label-MS Homo sapiens
428 VPS16 64601
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
429 COX17  
Co-fractionation Homo sapiens
430 ESYT2 57488
Proximity Label-MS Homo sapiens
431 KIAA0319L 79932
Proximity Label-MS Homo sapiens
432 UQCRQ 27089
Affinity Capture-MS Homo sapiens
433 GPRIN1 114787
Proximity Label-MS Homo sapiens
434 CYBRD1 79901
Affinity Capture-MS Homo sapiens
435 KIAA0196 9897
Proximity Label-MS Homo sapiens
436 HSPA8 3312
Co-fractionation Homo sapiens
437 CDC42BPA 8476
Proximity Label-MS Homo sapiens
438 TSC2 7249
Proximity Label-MS Homo sapiens
439 PLEKHA1 59338
Proximity Label-MS Homo sapiens
440 UBE2V1 7335
Co-fractionation Homo sapiens
441 PXMP2  
Proximity Label-MS Homo sapiens
442 LEMD3  
Proximity Label-MS Homo sapiens
443 EIF2AK3  
Proximity Label-MS Homo sapiens
444 ATP5A1 498
Co-fractionation Homo sapiens
445 SCFD1 23256
Proximity Label-MS Homo sapiens
446 FOXC1  
Affinity Capture-MS Homo sapiens
447 CPNE8 144402
Proximity Label-MS Homo sapiens
448 TEX264 51368
Proximity Label-MS Homo sapiens
449 TYW1B  
Proximity Label-MS Homo sapiens
450 BNIP1 662
Proximity Label-MS Homo sapiens
451 NDUFB7 4713
Affinity Capture-MS Homo sapiens
452 ZFYVE16  
Proximity Label-MS Homo sapiens
453 ITGA6 3655
Proximity Label-MS Homo sapiens
454 REEP4  
Proximity Label-MS Homo sapiens
455 PARK2  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
456 CXADR 1525
Proximity Label-MS Homo sapiens
457 CHCHD3 54927
Affinity Capture-MS Homo sapiens
458 GGCX 2677
Proximity Label-MS Homo sapiens
459 SZT2 23334
Co-localization Homo sapiens
460 RAB4A 5867
Proximity Label-MS Homo sapiens
Two-hybrid Homo sapiens
461 CBX3 11335
Proximity Label-MS Homo sapiens
462 ANKS6 203286
Proximity Label-MS Homo sapiens
463 DNAJC5 80331
Proximity Label-MS Homo sapiens
464 CHMP4B 128866
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
465 DIRAS3  
Proximity Label-MS Homo sapiens
466 SNX11 29916
Proximity Label-MS Homo sapiens
467 U2AF2 11338
Affinity Capture-MS Homo sapiens
468 PIKFYVE 200576
Proximity Label-MS Homo sapiens
469 SMAD2 4087
Proximity Label-MS Homo sapiens
470 OCIAD2 132299
Co-fractionation Homo sapiens
471 HMGCL 3155
Co-fractionation Homo sapiens
472 PIK3R1 5295
Proximity Label-MS Homo sapiens
473 GCC1 79571
Proximity Label-MS Homo sapiens
474 RAB10 10890
Co-fractionation Homo sapiens
475 KPNA5 3841
Proximity Label-MS Homo sapiens
476 HNRNPA3 220988
Co-fractionation Homo sapiens
477 GNG5 2787
Co-fractionation Homo sapiens
478 MFF 56947
Proximity Label-MS Homo sapiens
479 RMDN3 55177
Proximity Label-MS Homo sapiens
480 GPRC5A 9052
Affinity Capture-MS Homo sapiens
481 SLC4A7 9497
Proximity Label-MS Homo sapiens
482 COG2 22796
Proximity Label-MS Homo sapiens
483 ACAT1 38
Co-fractionation Homo sapiens
484 SMCR8 140775
Proximity Label-MS Homo sapiens
485 VPS13A 23230
Proximity Label-MS Homo sapiens
486 TMEM106B 54664
Proximity Label-MS Homo sapiens
487 ITPR2 3709
Proximity Label-MS Homo sapiens
488 EMC3 55831
Proximity Label-MS Homo sapiens
489 PIGT 51604
Proximity Label-MS Homo sapiens
490 KIAA1244  
Proximity Label-MS Homo sapiens
491 SNX19  
Proximity Label-MS Homo sapiens
492 ARFGEF1 10565
Proximity Label-MS Homo sapiens
493 VAMP3 9341
Affinity Capture-MS Homo sapiens
494 STIM1 6786
Proximity Label-MS Homo sapiens
495 RIC1 57589
Proximity Label-MS Homo sapiens
496 GBF1 8729
Proximity Label-MS Homo sapiens
497 KRTAP10-3  
Two-hybrid Homo sapiens
498 HPS3 84343
Proximity Label-MS Homo sapiens
499 SUN1 23353
Proximity Label-MS Homo sapiens
500 CORO1C 23603
Co-fractionation Homo sapiens
501 GOSR2 9570
Proximity Label-MS Homo sapiens
502 ECE1 1889
Proximity Label-MS Homo sapiens
503 OCIAD1 54940
Proximity Label-MS Homo sapiens
504 ITGA5 3678
Proximity Label-MS Homo sapiens
505 AP2M1 1173
Affinity Capture-MS Homo sapiens
506 DHX57 90957
Proximity Label-MS Homo sapiens
507 OSBPL11 114885
Proximity Label-MS Homo sapiens
508 CTSD 1509
Co-fractionation Homo sapiens
509 ZFYVE28  
Co-localization Homo sapiens
510 Flnb 286940
Affinity Capture-MS Mus musculus
511 RABAC1 10567
Affinity Capture-MS Homo sapiens
512 PTPN13 5783
Proximity Label-MS Homo sapiens
513 GNB2 2783
Affinity Capture-MS Homo sapiens
514 EMC2 9694
Proximity Label-MS Homo sapiens
515 SNX30 401548
Proximity Label-MS Homo sapiens
516 RAB11B 9230
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
517 KCNN4 3783
Affinity Capture-Western Homo sapiens
518 ACTB 60
Co-fractionation Homo sapiens
519 BICD1 636
Proximity Label-MS Homo sapiens
520 RPN1 6184
Proximity Label-MS Homo sapiens
521 KTN1 3895
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
522 SEH1L 81929
Proximity Label-MS Homo sapiens
523 HSPA9 3313
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
524 CHM 1121
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
525 ATP7A 538
Proximity Label-MS Homo sapiens
526 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
527 OSBPL1A 114876
Proximity Label-MS Homo sapiens
528 FLOT1 10211
Affinity Capture-MS Homo sapiens
529 ACBD5 91452
Proximity Label-MS Homo sapiens
530 UBE2J1 51465
Proximity Label-MS Homo sapiens
531 ATP6V1H 51606
Affinity Capture-MS Homo sapiens
532 IMMT 10989
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
533 GOLGA2 2801
Proximity Label-MS Homo sapiens
534 DMXL2  
Proximity Label-MS Homo sapiens
535 HEATR5B 54497
Proximity Label-MS Homo sapiens
536 PHB2 11331
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
537 ALDH3A2 224
Proximity Label-MS Homo sapiens
538 GPR89A  
Proximity Label-MS Homo sapiens
539 PEX1 5189
Proximity Label-MS Homo sapiens
540 JUP 3728
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
541 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
542 FBXW11  
Proximity Label-MS Homo sapiens
543 ERLIN1 10613
Affinity Capture-MS Homo sapiens
544 RPA1 6117
Affinity Capture-MS Homo sapiens
545 PLXNA1 5361
Proximity Label-MS Homo sapiens
546 EDEM1  
Affinity Capture-MS Homo sapiens
547 RPTOR 57521
Proximity Label-MS Homo sapiens
548 EFNB1 1947
Proximity Label-MS Homo sapiens
549 NHLRC2 374354
Affinity Capture-MS Homo sapiens
550 ERLIN2 11160
Affinity Capture-MS Homo sapiens
551 LAMTOR2 28956
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
552 SNAPIN 23557
Proximity Label-MS Homo sapiens
553 RHBDD3 25807
Proximity Label-MS Homo sapiens
554 ERGIC1 57222
Proximity Label-MS Homo sapiens
555 DDX58 23586
Affinity Capture-RNA Homo sapiens
556 ACSL4 2182
Proximity Label-MS Homo sapiens
557 MTSS1 9788
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
558 VPS18 57617
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
559 SPG11 80208
Proximity Label-MS Homo sapiens
560 RUFY2  
Proximity Label-MS Homo sapiens
561 INF2 64423
Proximity Label-MS Homo sapiens
562 LRRK2 120892
Affinity Capture-Western Homo sapiens
563 FIS1 51024
Proximity Label-MS Homo sapiens
564 LRP2 4036
Proximity Label-MS Homo sapiens
565 TMEM38B  
Proximity Label-MS Homo sapiens
566 TENM1  
Proximity Label-MS Homo sapiens
567 STT3B 201595
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
568 SNX2 6643
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
569 VPS39 23339
Reconstituted Complex Homo sapiens
570 VDAC3 7419
Co-fractionation Homo sapiens
571 CAV1 857
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
572 NOTCH1 4851
Affinity Capture-Western Homo sapiens
573 HLA-C 3107
Proximity Label-MS Homo sapiens
574 KIAA0922  
Proximity Label-MS Homo sapiens
575 TBC1D22A  
Proximity Label-MS Homo sapiens
576 RAB22A 57403
Two-hybrid Homo sapiens
577 ABCG2 9429
Affinity Capture-MS Homo sapiens
578 VPS35 55737
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
579 SLC29A1 2030
Proximity Label-MS Homo sapiens
580 HSD17B11 51170
Proximity Label-MS Homo sapiens
581 SCIN 85477
Proximity Label-MS Homo sapiens
582 POR 5447
Proximity Label-MS Homo sapiens
583 SNX3 8724
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
584 VTI1B 10490
Proximity Label-MS Homo sapiens
585 SNAP23 8773
Proximity Label-MS Homo sapiens
586 TMEM161A  
Proximity Label-MS Homo sapiens
587 VAPA 9218
Proximity Label-MS Homo sapiens
588 AKAP12 9590
Proximity Label-MS Homo sapiens
589 RPL37A 6168
Cross-Linking-MS (XL-MS) Homo sapiens
590 CISD1 55847
Proximity Label-MS Homo sapiens
591 TSG101 7251
Co-localization Homo sapiens
592 LAMP2 3920
Proximity Label-MS Homo sapiens
593 DNAJC25 548645
Proximity Label-MS Homo sapiens
594 PLEKHA2 59339
Affinity Capture-MS Homo sapiens
595 LNPEP 4012
Proximity Label-MS Homo sapiens
596 CFL1 1072
Affinity Capture-MS Homo sapiens
597 SLC12A2 6558
Proximity Label-MS Homo sapiens
598 VPS29 51699
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
599 HSPA5 3309
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
600 KIAA1429 25962
Affinity Capture-MS Homo sapiens
601 B3GAT1  
Proximity Label-MS Homo sapiens
602 PRDX3 10935
Co-fractionation Homo sapiens
603 PC 5091
Affinity Capture-MS Homo sapiens
604 SLC39A10 57181
Proximity Label-MS Homo sapiens
605 DCTN4 51164
Proximity Label-MS Homo sapiens
606 NDUFA7 4701
Affinity Capture-MS Homo sapiens
607 CYB5R1 51706
Co-fractionation Homo sapiens
608 STIM2 57620
Proximity Label-MS Homo sapiens
609 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
610 CPD 1362
Proximity Label-MS Homo sapiens
611 STX7 8417
Proximity Label-MS Homo sapiens
612 STX18 53407
Proximity Label-MS Homo sapiens
613 DDOST 1650
Affinity Capture-MS Homo sapiens
614 RTN1 6252
Proximity Label-MS Homo sapiens
615 ATP5O 539
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
616 FAM135A  
Proximity Label-MS Homo sapiens
617 STX6 10228
Proximity Label-MS Homo sapiens
618 SLC30A5 64924
Proximity Label-MS Homo sapiens
619 EED  
Affinity Capture-MS Homo sapiens
620 CCDC115 84317
Affinity Capture-MS Homo sapiens
621 ATP6V0D1 9114
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
622 PPP1R15B  
Proximity Label-MS Homo sapiens
623 SEC23A 10484
Proximity Label-MS Homo sapiens
624 RAB35 11021
Proximity Label-MS Homo sapiens
625 FAF2 23197
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
626 TMEM2 23670
Proximity Label-MS Homo sapiens
627 ATG2B 55102
Proximity Label-MS Homo sapiens
628 ATP6AP1 537
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
629 VAMP8 8673
Proximity Label-MS Homo sapiens
630 LAMTOR1 55004
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
631 RAB1B 81876
Co-fractionation Homo sapiens
632 ATF6  
Proximity Label-MS Homo sapiens
633 EIF1B  
Affinity Capture-MS Homo sapiens
634 STOML2 30968
Affinity Capture-MS Homo sapiens
635 SEMA4C 54910
Proximity Label-MS Homo sapiens
636 VKORC1L1 154807
Proximity Label-MS Homo sapiens
637 VEZT 55591
Proximity Label-MS Homo sapiens
638 CYB5R3 1727
Co-fractionation Homo sapiens
639 PRDX5 25824
Co-fractionation Homo sapiens
640 ANGEL1  
Proximity Label-MS Homo sapiens
641 COX15 1355
Affinity Capture-MS Homo sapiens
642 ITGAV 3685
Proximity Label-MS Homo sapiens
643 EMD 2010
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
644 STEAP3 55240
Proximity Label-MS Homo sapiens
645 LRIG2  
Proximity Label-MS Homo sapiens
646 HSP90B1 7184
Co-fractionation Homo sapiens
647 ATF2  
Affinity Capture-MS Homo sapiens
648 USMG5 84833
Co-fractionation Homo sapiens
649 SREBF2 6721
Proximity Label-MS Homo sapiens
650 PLEKHM2 23207
Proximity Label-MS Homo sapiens
651 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
652 ATP9A 10079
Proximity Label-MS Homo sapiens
653 TBC1D15 64786
Proximity Label-MS Homo sapiens
654 RILP 83547
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
655 EXD2  
Proximity Label-MS Homo sapiens
656 PI4KB 5298
Proximity Label-MS Homo sapiens
657 SLC7A2 6542
Proximity Label-MS Homo sapiens
658 ITPR1 3708
Proximity Label-MS Homo sapiens
659 GOPC 57120
Proximity Label-MS Homo sapiens
660 DDX54 79039
Proximity Label-MS Homo sapiens
661 CHCHD6 84303
Affinity Capture-MS Homo sapiens
662 VMA21  
Proximity Label-MS Homo sapiens
663 RAB11FIP5 26056
Proximity Label-MS Homo sapiens
664 DEF8  
Proximity Label-MS Homo sapiens
665 ELOVL5 60481
Proximity Label-MS Homo sapiens
666 COG4 25839
Proximity Label-MS Homo sapiens
667 ATP5B 506
Co-fractionation Homo sapiens
668 WDFY1 57590
Affinity Capture-MS Homo sapiens
669 USP32 84669
Proximity Label-MS Homo sapiens
670 SNX4 8723
Proximity Label-MS Homo sapiens
671 TEX2 55852
Proximity Label-MS Homo sapiens
672 BAG3 9531
Affinity Capture-MS Homo sapiens
673 SNX1 6642
Proximity Label-MS Homo sapiens
674 MEGF8 1954
Proximity Label-MS Homo sapiens
675 SEC63 11231
Proximity Label-MS Homo sapiens
676 FNIP1  
Proximity Label-MS Homo sapiens
677 MAD2L1 4085
Proximity Label-MS Homo sapiens
678 ANKRD27  
Proximity Label-MS Homo sapiens
679 RALGAPA1 253959
Proximity Label-MS Homo sapiens
680 HSD3B7 80270
Proximity Label-MS Homo sapiens
681 WDR45  
Proximity Label-MS Homo sapiens
682 VAPB 9217
Proximity Label-MS Homo sapiens
683 MADD 8567
Proximity Label-MS Homo sapiens
684 SLC3A2 6520
Proximity Label-MS Homo sapiens
685 SLC2A4  
Affinity Capture-MS Homo sapiens
686 CDKAL1  
Proximity Label-MS Homo sapiens
687 ATP2B1 490
Affinity Capture-MS Homo sapiens
688 LETM1 3954
Co-fractionation Homo sapiens
689 UQCRC2 7385
Co-fractionation Homo sapiens
690 HMOX2 3163
Proximity Label-MS Homo sapiens
691 LAMP1 3916
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
692 Bmpr1a  
Affinity Capture-MS Mus musculus
693 FAM171A1 221061
Proximity Label-MS Homo sapiens
694 SLC35E1 79939
Proximity Label-MS Homo sapiens
695 COX7A2 1347
Co-fractionation Homo sapiens
696 ARF6 382
Proximity Label-MS Homo sapiens
697 RABGAP1 23637
Proximity Label-MS Homo sapiens
698 LPCAT3 10162
Proximity Label-MS Homo sapiens
699 GDI2 2665
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
700 ADAM22  
Proximity Label-MS Homo sapiens
701 UVRAG  
Proximity Label-MS Homo sapiens
702 COG6 57511
Proximity Label-MS Homo sapiens
703 TMEM131  
Proximity Label-MS Homo sapiens
704 YME1L1 10730
Proximity Label-MS Homo sapiens
705 MYOF 26509
Affinity Capture-MS Homo sapiens
706 MSI2 124540
Co-fractionation Homo sapiens
707 ATP6V1A 523
Affinity Capture-MS Homo sapiens
708 TRAPPC12 51112
Proximity Label-MS Homo sapiens
709 PIK3R2 5296
Proximity Label-MS Homo sapiens
710 PPFIBP1 8496
Proximity Label-MS Homo sapiens
711 YIPF5 81555
Affinity Capture-MS Homo sapiens
712 FNDC3A 22862
Proximity Label-MS Homo sapiens
713 STBD1 8987
Proximity Label-MS Homo sapiens
714 SCD 6319
Proximity Label-MS Homo sapiens
715 VDAC1 7416
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
716 STX10 8677
Proximity Label-MS Homo sapiens
717 RUNDC3B  
Proximity Label-MS Homo sapiens
718 DOCK6 57572
Proximity Label-MS Homo sapiens
719 CLCN5 1184
Affinity Capture-MS Homo sapiens
720 DNAJC13 23317
Proximity Label-MS Homo sapiens
721 SEC24B 10427
Proximity Label-MS Homo sapiens
722 LBR 3930
Proximity Label-MS Homo sapiens
723 ADAM17 6868
Proximity Label-MS Homo sapiens
724 USE1 55850
Proximity Label-MS Homo sapiens
725 RRBP1 6238
Proximity Label-MS Homo sapiens
726 BKRF1  
Affinity Capture-MS
727 RUFY3  
Proximity Label-MS Homo sapiens
728 UBXN4 23190
Proximity Label-MS Homo sapiens
729 BLOC1S2 282991
Proximity Label-MS Homo sapiens
730 SLC1A1 6505
Proximity Label-MS Homo sapiens
731 LGALS3 3958
Co-localization Homo sapiens
732 DOPEY2 9980
Proximity Label-MS Homo sapiens
733 TYW1  
Proximity Label-MS Homo sapiens
734 PIGK 10026
Proximity Label-MS Homo sapiens
735 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
736 CAPNS1 826
Proximity Label-MS Homo sapiens
737 NISCH 11188
Proximity Label-MS Homo sapiens
738 NUP35 129401
Proximity Label-MS Homo sapiens
739 ATP2A2 488
Affinity Capture-MS Homo sapiens
740 STARD3 10948
Proximity Label-MS Homo sapiens
741 ATP6V1F 9296
Proximity Label-MS Homo sapiens
742 SFXN1 94081
Co-fractionation Homo sapiens
743 FADS2 9415
Proximity Label-MS Homo sapiens
744 NUP50 10762
Proximity Label-MS Homo sapiens
745 MIOS 54468
Proximity Label-MS Homo sapiens
746 RETSAT 54884
Proximity Label-MS Homo sapiens
747 SEC62 7095
Proximity Label-MS Homo sapiens
748 RPS6 6194
Proximity Label-MS Homo sapiens
749 CDK5RAP3 80279
Proximity Label-MS Homo sapiens
750 WDR59 79726
Proximity Label-MS Homo sapiens
751 MOSPD2 158747
Proximity Label-MS Homo sapiens
752 DNAJC1 64215
Proximity Label-MS Homo sapiens
753 OAZ1 4946
Affinity Capture-MS Homo sapiens
754 C9orf72  
Proximity Label-MS Homo sapiens
755 HS1BP3 64342
Proximity Label-MS Homo sapiens
756 RAB23 51715
Proximity Label-MS Homo sapiens
757 ESYT1 23344
Proximity Label-MS Homo sapiens
758 DSG2 1829
Proximity Label-MS Homo sapiens
759 KRTAP10-9  
Two-hybrid Homo sapiens
View the network image/svg+xml



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