Gene description for NUTF2
Gene name nuclear transport factor 2
Gene symbol NUTF2
Other names/aliases NTF2
PP15
Species Homo sapiens
 Database cross references - NUTF2
ExoCarta ExoCarta_10204
Entrez Gene 10204
HGNC 13722
MIM 605813
UniProt P61970  
 NUTF2 identified in exosomes derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Urine 15326289    
 Gene ontology annotations for NUTF2
Molecular Function
    protein binding GO:0005515 IPI
    Ran GTPase binding GO:0008536 IPI
    transporter activity GO:0005215 TAS
Biological Process
    protein export from nucleus GO:0006611 IDA
    protein import into nucleus, translocation GO:0000060 IMP
Subcellular Localization
    cytosol GO:0005829 TAS
    extracellular exosome GO:0070062 IDA
    nuclear pore GO:0005643 TAS
 Experiment description of studies that identified NUTF2 in exosomes
1
Experiment ID 79
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD81|MHCII
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W.
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
CD81|MHCII
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W.
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 13
ISEV standards
IEM
EV Biophysical techniques
Alix|RAB4|RAB5B|RAB11|TSG101
EV Cytosolic markers
CD9|AQP2|AQP1
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors Pisitkun T, Shen RF, Knepper MA
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
 Protein-protein interactions for NUTF2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NUP54  
Reconstituted Complex Homo sapiens
2 NUP62 23636
Reconstituted Complex Homo sapiens
Invitro Homo sapiens
3 NUP153  
Reconstituted Complex Homo sapiens
4 NUTF2 10204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 RAN 5901
Invivo Homo sapiens
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Invivo Homo sapiens
Invivo Homo sapiens
Invitro Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
6 LUC7L2  
Two-hybrid Homo sapiens
7 PTMA 5757
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which NUTF2 is involved
No pathways found





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