Gene description for DERL1
Gene name derlin 1
Gene symbol DERL1
Other names/aliases DER-1
DER1
Species Homo sapiens
 Database cross references - DERL1
ExoCarta ExoCarta_79139
Vesiclepedia VP_79139
Entrez Gene 79139
HGNC 28454
MIM 608813
UniProt Q9BUN8  
 DERL1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Squamous carcinoma cells 20124223    
 Gene ontology annotations for DERL1
Molecular Function
    protease binding GO:0002020 IPI
    signal recognition particle binding GO:0005047 IBA
    signal recognition particle binding GO:0005047 IDA
    protein binding GO:0005515 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
    signaling receptor activity GO:0038023 NAS
    MHC class I protein binding GO:0042288 IDA
    identical protein binding GO:0042802 IPI
    protein-containing complex binding GO:0044877 IPI
    ATPase binding GO:0051117 IPI
    ubiquitin-specific protease binding GO:1990381 IPI
Biological Process
    response to unfolded protein GO:0006986 IMP
    endoplasmic reticulum unfolded protein response GO:0030968 IBA
    endoplasmic reticulum unfolded protein response GO:0030968 IDA
    retrograde protein transport, ER to cytosol GO:0030970 IDA
    retrograde protein transport, ER to cytosol GO:0030970 IMP
    retrograde protein transport, ER to cytosol GO:0030970 IMP
    positive regulation of protein ubiquitination GO:0031398 IDA
    protein destabilization GO:0031648 IMP
    ERAD pathway GO:0036503 IBA
    ERAD pathway GO:0036503 IDA
    ERAD pathway GO:0036503 IMP
    ERAD pathway GO:0036503 TAS
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IEA
    establishment of protein localization GO:0045184 TAS
    cellular response to misfolded protein GO:0071218 IMP
Subcellular Localization
    early endosome GO:0005769 IEA
    late endosome GO:0005770 IEA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum GO:0005783 IMP
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 IDA
    endoplasmic reticulum membrane GO:0005789 TAS
    membrane GO:0016020 HDA
    membrane GO:0016020 IDA
    Derlin-1-VIMP complex GO:0036502 IDA
    Derlin-1 retrotranslocation complex GO:0036513 IDA
    endoplasmic reticulum quality control compartment GO:0044322 IEA
 Experiment description of studies that identified DERL1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for DERL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 ARHGAP1 392
Proximity Label-MS Homo sapiens
4 Dctn1 13191
Affinity Capture-MS Mus musculus
5 SRPRB 58477
Proximity Label-MS Homo sapiens
6 JPH1 56704
Proximity Label-MS Homo sapiens
7 VMP1 81671
Proximity Label-MS Homo sapiens
8 MARC1  
Proximity Label-MS Homo sapiens
9 TACC2 10579
Proximity Label-MS Homo sapiens
10 LPCAT1 79888
Proximity Label-MS Homo sapiens
11 PTRH2 51651
Proximity Label-MS Homo sapiens
12 PALD1 27143
Proximity Label-MS Homo sapiens
13 IARS2 55699
Proximity Label-MS Homo sapiens
14 RINT1 60561
Proximity Label-MS Homo sapiens
15 TMEM41B 440026
Proximity Label-MS Homo sapiens
16 AP2A1 160
Proximity Label-MS Homo sapiens
17 SMPD4 55627
Proximity Label-MS Homo sapiens
18 DGKE  
Proximity Label-MS Homo sapiens
19 SEL1L 6400
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
20 PSMB6 5694
Affinity Capture-MS Homo sapiens
21 TMEM201 199953
Proximity Label-MS Homo sapiens
22 LRRC41 10489
Proximity Label-MS Homo sapiens
23 USP33  
Proximity Label-MS Homo sapiens
24 BET1 10282
Proximity Label-MS Homo sapiens
25 MECP2 4204
Affinity Capture-MS Homo sapiens
26 VWA8 23078
Proximity Label-MS Homo sapiens
27 FAM177A1 283635
Proximity Label-MS Homo sapiens
28 ZFAND2B  
Affinity Capture-Western Homo sapiens
29 NOTCH2 4853
Proximity Label-MS Homo sapiens
30 EMC1 23065
Affinity Capture-MS Homo sapiens
31 CAMLG 819
Proximity Label-MS Homo sapiens
32 FAM96A  
Two-hybrid Homo sapiens
33 TCP1 6950
Affinity Capture-MS Homo sapiens
34 SENP2 59343
Proximity Label-MS Homo sapiens
35 USP14 9097
Affinity Capture-MS Homo sapiens
36 TMX1 81542
Proximity Label-MS Homo sapiens
37 P2RY8  
Affinity Capture-MS Homo sapiens
38 ILVBL 10994
Proximity Label-MS Homo sapiens
39 AKAP1 8165
Proximity Label-MS Homo sapiens
40 UBAC2 337867
Proximity Label-MS Homo sapiens
41 UBXN8  
Proximity Label-MS Homo sapiens
42 CLCC1 23155
Proximity Label-MS Homo sapiens
43 PSMD2 5708
Affinity Capture-MS Homo sapiens
44 VAPB 9217
Proximity Label-MS Homo sapiens
45 GORASP2 26003
Proximity Label-MS Homo sapiens
46 FRAS1 80144
Proximity Label-MS Homo sapiens
47 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
48 AHCTF1 25909
Proximity Label-MS Homo sapiens
49 SEC61B 10952
Proximity Label-MS Homo sapiens
50 YOD1  
Affinity Capture-Western Homo sapiens
51 CACYBP 27101
Affinity Capture-MS Homo sapiens
52 REEP5 7905
Proximity Label-MS Homo sapiens
53 TMPO 7112
Proximity Label-MS Homo sapiens
54 ANO6 196527
Proximity Label-MS Homo sapiens
55 VIPR2  
Affinity Capture-MS Homo sapiens
56 LRRC59 55379
Proximity Label-MS Homo sapiens
57 CDCA3 83461
Proximity Label-MS Homo sapiens
58 SRSF4 6429
Proximity Label-MS Homo sapiens
59 TMED8 283578
Two-hybrid Homo sapiens
60 BCAP31 10134
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
61 TMEM199  
Proximity Label-MS Homo sapiens
62 ATP6AP2 10159
Proximity Label-MS Homo sapiens
63 OPA1 4976
Proximity Label-MS Homo sapiens
64 MBOAT1  
Affinity Capture-MS Homo sapiens
65 FKBP8 23770
Proximity Label-MS Homo sapiens
66 AAAS 8086
Proximity Label-MS Homo sapiens
67 KCNB2  
Proximity Label-MS Homo sapiens
68 XBP1  
Affinity Capture-Western Homo sapiens
69 SNX19  
Proximity Label-MS Homo sapiens
70 TMEM173  
Proximity Label-MS Homo sapiens
71 ZW10 9183
Proximity Label-MS Homo sapiens
72 SOAT1 6646
Proximity Label-MS Homo sapiens
73 UBA2 10054
Affinity Capture-MS Homo sapiens
74 RPA3 6119
Proximity Label-MS Homo sapiens
75 TMCO1 54499
Proximity Label-MS Homo sapiens
76 ABCC1 4363
Proximity Label-MS Homo sapiens
77 NCLN 56926
Affinity Capture-MS Homo sapiens
78 GANAB 23193
Affinity Capture-MS Homo sapiens
79 PEX3 8504
Proximity Label-MS Homo sapiens
80 HIST1H2AJ 8331
Affinity Capture-MS Homo sapiens
81 TMX2 51075
Two-hybrid Homo sapiens
82 YIF1B 90522
Affinity Capture-MS Homo sapiens
83 GAD2  
Two-hybrid Homo sapiens
84 TMEM57  
Proximity Label-MS Homo sapiens
85 AGPAT9  
Proximity Label-MS Homo sapiens
86 ZFYVE27 118813
Proximity Label-MS Homo sapiens
87 RUVBL2 10856
Affinity Capture-MS Homo sapiens
88 FCGRT 2217
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
89 EMC7 56851
Proximity Label-MS Homo sapiens
90 PSMB7 5695
Affinity Capture-MS Homo sapiens
91 CLPTM1 1209
Proximity Label-MS Homo sapiens
92 EPHX1 2052
Affinity Capture-MS Homo sapiens
93 Smo  
Affinity Capture-MS Mus musculus
94 PTPN2 5771
Proximity Label-MS Homo sapiens
95 ITPR3 3710
Proximity Label-MS Homo sapiens
96 PSMA1 5682
Affinity Capture-MS Homo sapiens
97 RABL3 285282
Proximity Label-MS Homo sapiens
98 SHH  
Affinity Capture-Western Homo sapiens
99 HM13 81502
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
100 NDC1 55706
Proximity Label-MS Homo sapiens
101 ITPR1 3708
Proximity Label-MS Homo sapiens
102 EI24  
Proximity Label-MS Homo sapiens
103 CISD2 493856
Proximity Label-MS Homo sapiens
104 HERPUD1  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
105 PRAF2 11230
Proximity Label-MS Homo sapiens
106 VANGL1 81839
Proximity Label-MS Homo sapiens
107 PPP2R2A 5520
Affinity Capture-MS Homo sapiens
108 HSPA1B 3304
Affinity Capture-MS Homo sapiens
109 GNAI3 2773
Proximity Label-MS Homo sapiens
110 PSMD3 5709
Affinity Capture-MS Homo sapiens
111 PSMA6 5687
Affinity Capture-MS Homo sapiens
112 HMOX1 3162
Affinity Capture-MS Homo sapiens
113 DDHD2 23259
Proximity Label-MS Homo sapiens
114 ERN1  
Affinity Capture-Western Homo sapiens
115 CAMSAP1 157922
Proximity Label-MS Homo sapiens
116 ATL1 51062
Proximity Label-MS Homo sapiens
117 ANP32A 8125
Affinity Capture-MS Homo sapiens
118 DHRS7 51635
Proximity Label-MS Homo sapiens
119 ARL6IP5 10550
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
120 RPA2 6118
Proximity Label-MS Homo sapiens
121 ARFGAP2 84364
Proximity Label-MS Homo sapiens
122 ALB 213
Affinity Capture-MS Homo sapiens
123 UCHL1 7345
Affinity Capture-MS Homo sapiens
124 BSCL2  
Affinity Capture-MS Homo sapiens
125 SPTLC1 10558
Proximity Label-MS Homo sapiens
126 GOSR2 9570
Proximity Label-MS Homo sapiens
127 CAND1 55832
Affinity Capture-MS Homo sapiens
128 SYVN1 84447
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
129 COPA 1314
Proximity Label-MS Homo sapiens
130 UBE2N 7334
Affinity Capture-MS Homo sapiens
131 FFAR1  
Affinity Capture-MS Homo sapiens
132 NUP160 23279
Proximity Label-MS Homo sapiens
133 VANGL2  
Proximity Label-MS Homo sapiens
134 WDR41  
Proximity Label-MS Homo sapiens
135 RHO  
Reconstituted Complex Homo sapiens
136 RNF103  
Affinity Capture-Western Homo sapiens
137 FCRL4  
Two-hybrid Homo sapiens
138 ACLY 47
Affinity Capture-MS Homo sapiens
139 SCD5  
Proximity Label-MS Homo sapiens
140 LMAN1 3998
Proximity Label-MS Homo sapiens
141 KIAA1715 80856
Proximity Label-MS Homo sapiens
142 CHMP7 91782
Proximity Label-MS Homo sapiens
143 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 AMFR 267
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
145 SNAP47 116841
Proximity Label-MS Homo sapiens
146 CDKAL1  
Proximity Label-MS Homo sapiens
147 PBXIP1 57326
Proximity Label-MS Homo sapiens
148 CACNA1C  
Affinity Capture-Western Homo sapiens
149 LYSMD3  
Proximity Label-MS Homo sapiens
150 TAPT1 202018
Proximity Label-MS Homo sapiens
151 APOB 338
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
152 PREB 10113
Proximity Label-MS Homo sapiens
153 TMEM63A 9725
Affinity Capture-MS Homo sapiens
154 STX5 6811
Proximity Label-MS Homo sapiens
155 TMEM131  
Proximity Label-MS Homo sapiens
156 UBXN6 80700
Reconstituted Complex Homo sapiens
157 CLN6  
Affinity Capture-Western Homo sapiens
158 SGPL1 8879
Proximity Label-MS Homo sapiens
159 SMCHD1 23347
Affinity Capture-MS Homo sapiens
160 CANX 821
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
161 EMC8 10328
Proximity Label-MS Homo sapiens
162 ADCY9 115
Proximity Label-MS Homo sapiens
163 PNP 4860
Affinity Capture-MS Homo sapiens
164 Rmdn3  
Affinity Capture-MS Mus musculus
165 EGFR 1956
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
166 TMEM194A  
Proximity Label-MS Homo sapiens
167 ABHD12 26090
Proximity Label-MS Homo sapiens
168 SEC24A 10802
Proximity Label-MS Homo sapiens
169 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
170 FAM134B 54463
Proximity Label-MS Homo sapiens
171 VRK2 7444
Proximity Label-MS Homo sapiens
172 DDB1 1642
Affinity Capture-MS Homo sapiens
173 DDRGK1 65992
Proximity Label-MS Homo sapiens
174 XRCC3  
Affinity Capture-MS Homo sapiens
175 TMEM209 84928
Proximity Label-MS Homo sapiens
176 VIMP 55829
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
177 LEMD3  
Proximity Label-MS Homo sapiens
178 ENTHD2  
Affinity Capture-MS Homo sapiens
179 OSBPL8 114882
Proximity Label-MS Homo sapiens
180 GRAMD1B  
Proximity Label-MS Homo sapiens
181 RAE1 8480
Proximity Label-MS Homo sapiens
182 HUWE1 10075
Affinity Capture-MS Homo sapiens
183 TCF25 22980
Two-hybrid Homo sapiens
184 AVPR2  
Affinity Capture-Western Homo sapiens
185 RAB18 22931
Proximity Label-MS Homo sapiens
186 CLPP 8192
Proximity Label-MS Homo sapiens
187 SUN1 23353
Proximity Label-MS Homo sapiens
188 PLXNB2 23654
Proximity Label-MS Homo sapiens
189 SLC38A2 54407
Proximity Label-MS Homo sapiens
190 TRIM13  
Proximity Label-MS Homo sapiens
191 TMEM9 252839
Proximity Label-MS Homo sapiens
192 PARP1 142
Affinity Capture-MS Homo sapiens
193 PGRMC1 10857
Proximity Label-MS Homo sapiens
194 RTN3 10313
Proximity Label-MS Homo sapiens
195 MTMR3  
Proximity Label-MS Homo sapiens
196 PDCL 5082
Proximity Label-MS Homo sapiens
197 NSDHL 50814
Proximity Label-MS Homo sapiens
198 TSC1 7248
Proximity Label-MS Homo sapiens
199 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
200 MMGT1 93380
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
201 AUP1 550
Proximity Label-MS Homo sapiens
202 NOC2L 26155
Proximity Label-MS Homo sapiens
203 TMX4 56255
Proximity Label-MS Homo sapiens
204 ATP1A1 476
Proximity Label-MS Homo sapiens
205 TMEM109 79073
Proximity Label-MS Homo sapiens
206 YKT6 10652
Proximity Label-MS Homo sapiens
207 IGF2R 3482
Proximity Label-MS Homo sapiens
208 PSMD1 5707
Affinity Capture-MS Homo sapiens
209 CKAP4 10970
Proximity Label-MS Homo sapiens
210 SLC1A1 6505
Affinity Capture-MS Homo sapiens
211 EIF2AK3  
Proximity Label-MS Homo sapiens
212 FPR2  
Affinity Capture-MS Homo sapiens
213 ATP13A1 57130
Proximity Label-MS Homo sapiens
214 NUPL2 11097
Proximity Label-MS Homo sapiens
215 HACD3 51495
Proximity Label-MS Homo sapiens
216 SLC30A8  
Two-hybrid Homo sapiens
217 CLCN7 1186
Proximity Label-MS Homo sapiens
218 C2CD2L 9854
Proximity Label-MS Homo sapiens
219 Hax1  
Affinity Capture-MS Mus musculus
220 CD99 4267
Proximity Label-MS Homo sapiens
221 DHCR24 1718
Proximity Label-MS Homo sapiens
222 AKAP11 11215
Proximity Label-MS Homo sapiens
223 NBAS 51594
Proximity Label-MS Homo sapiens
224 SYNE2 23224
Proximity Label-MS Homo sapiens
225 PTPN1 5770
Proximity Label-MS Homo sapiens
226 APBB1  
Proximity Label-MS Homo sapiens
227 DERL1 79139
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
228 RTN4 57142
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
229 LRPPRC 10128
Proximity Label-MS Homo sapiens
230 TEX264 51368
Proximity Label-MS Homo sapiens
231 RNF5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
232 MCM2 4171
Affinity Capture-MS Homo sapiens
233 SENP1  
Proximity Label-MS Homo sapiens
234 STX8 9482
Proximity Label-MS Homo sapiens
235 DSC2 1824
Proximity Label-MS Homo sapiens
236 NUP210 23225
Proximity Label-MS Homo sapiens
237 LSG1  
Proximity Label-MS Homo sapiens
238 SSR1 6745
Proximity Label-MS Homo sapiens
239 PSMC2 5701
Affinity Capture-MS Homo sapiens
240 CCDC47 57003
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
241 GART 2618
Affinity Capture-MS Homo sapiens
242 MXRA7 439921
Proximity Label-MS Homo sapiens
243 MTDH 92140
Proximity Label-MS Homo sapiens
244 ESYT2 57488
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
245 VAPA 9218
Proximity Label-MS Homo sapiens
246 GBA2  
Proximity Label-MS Homo sapiens
247 HSPA8 3312
Affinity Capture-MS Homo sapiens
248 MDH2 4191
Affinity Capture-MS Homo sapiens
249 NUP155 9631
Proximity Label-MS Homo sapiens
250 DNAJC14  
Proximity Label-MS Homo sapiens
251 EPB41L3 23136
Affinity Capture-MS Homo sapiens
252 IRS4 8471
Affinity Capture-MS Homo sapiens
253 SCFD1 23256
Proximity Label-MS Homo sapiens
254 BNIP1 662
Proximity Label-MS Homo sapiens
255 REEP4  
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
256 PTGS2 5743
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
257 TRAM1 23471
Affinity Capture-Western Homo sapiens
258 Klhl21  
Affinity Capture-MS Mus musculus
259 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
260 TACC1 6867
Proximity Label-MS Homo sapiens
261 RAB3GAP1 22930
Proximity Label-MS Homo sapiens
262 SCN3B  
Two-hybrid Homo sapiens
263 ARFGAP3 26286
Proximity Label-MS Homo sapiens
264 SLC4A7 9497
Proximity Label-MS Homo sapiens
265 SMCR8 140775
Proximity Label-MS Homo sapiens
266 SRPR 6734
Proximity Label-MS Homo sapiens
267 ITPR2 3709
Proximity Label-MS Homo sapiens
268 AHCY 191
Affinity Capture-MS Homo sapiens
269 DNAJB12 54788
Proximity Label-MS Homo sapiens
270 ATF6  
Proximity Label-MS Homo sapiens
271 SAR1A 56681
Proximity Label-MS Homo sapiens
272 VAMP3 9341
Proximity Label-MS Homo sapiens
273 NR3C1 2908
Proximity Label-MS Homo sapiens
274 STIM1 6786
Proximity Label-MS Homo sapiens
275 OCIAD1 54940
Proximity Label-MS Homo sapiens
276 OSBPL11 114885
Proximity Label-MS Homo sapiens
277 FAM134C 162427
Two-hybrid Homo sapiens
278 EMC2 9694
Proximity Label-MS Homo sapiens
279 SEC16A 9919
Proximity Label-MS Homo sapiens
280 SLC10A1  
Two-hybrid Homo sapiens
281 RPN1 6184
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
282 KTN1 3895
Proximity Label-MS Homo sapiens
283 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
284 RNF185  
Affinity Capture-Western Homo sapiens
285 HLA-A 3105
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
286 FAM114A2  
Proximity Label-MS Homo sapiens
287 MAGT1 84061
Proximity Label-MS Homo sapiens
288 UBXN4 23190
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
289 XRCC5 7520
Affinity Capture-MS Homo sapiens
290 ACBD5 91452
Proximity Label-MS Homo sapiens
291 UBE2J1 51465
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
292 ALDH3A2 224
Proximity Label-MS Homo sapiens
293 RAB3GAP2 25782
Proximity Label-MS Homo sapiens
294 SEC23IP 11196
Proximity Label-MS Homo sapiens
295 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
296 ATL2 64225
Proximity Label-MS Homo sapiens
297 RPA1 6117
Affinity Capture-MS Homo sapiens
298 TMEM214 54867
Proximity Label-MS Homo sapiens
299 EDEM1  
Co-fractionation Homo sapiens
300 ERLIN2 11160
Affinity Capture-Western Homo sapiens
301 REEP2  
Proximity Label-MS Homo sapiens
302 DDX58 23586
Affinity Capture-RNA Homo sapiens
303 TRIM25 7706
Affinity Capture-MS Homo sapiens
304 PDZD8 118987
Proximity Label-MS Homo sapiens
305 UFL1 23376
Proximity Label-MS Homo sapiens
306 SMIM12  
Proximity Label-MS Homo sapiens
307 INF2 64423
Proximity Label-MS Homo sapiens
308 NEDD1 121441
Affinity Capture-MS Homo sapiens
309 RAB7A 7879
Proximity Label-MS Homo sapiens
310 TMEM38B  
Proximity Label-MS Homo sapiens
311 AGPAT6 137964
Proximity Label-MS Homo sapiens
312 STT3B 201595
Proximity Label-MS Homo sapiens
313 Shcbp1 20419
Affinity Capture-MS Mus musculus
314 TMEM31  
Two-hybrid Homo sapiens
315 RBM34  
Proximity Label-MS Homo sapiens
316 CAV1 857
Affinity Capture-Western Homo sapiens
317 SPCS2 9789
Proximity Label-MS Homo sapiens
318 HLA-C 3107
Proximity Label-MS Homo sapiens
319 UTP18  
Proximity Label-MS Homo sapiens
320 POR 5447
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
321 ANKLE2 23141
Proximity Label-MS Homo sapiens
322 SLC10A6  
Two-hybrid Homo sapiens
323 DERL2 51009
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
324 SCNN1A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
325 CD3D 915
Affinity Capture-Western Homo sapiens
326 PSMD11 5717
Affinity Capture-MS Homo sapiens
327 KPNB1 3837
Affinity Capture-Western Homo sapiens
328 ASGR2  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
329 GRAMD1A  
Proximity Label-MS Homo sapiens
330 SRP72 6731
Proximity Label-MS Homo sapiens
331 SLC12A2 6558
Proximity Label-MS Homo sapiens
332 APP 351
Reconstituted Complex Homo sapiens
333 TBC1D20  
Proximity Label-MS Homo sapiens
334 SLC39A10 57181
Proximity Label-MS Homo sapiens
335 CYB5R1 51706
Proximity Label-MS Homo sapiens
336 STIM2 57620
Proximity Label-MS Homo sapiens
337 CPD 1362
Proximity Label-MS Homo sapiens
338 SLC27A2 11001
Proximity Label-MS Homo sapiens
339 TMEM129  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
340 STX18 53407
Proximity Label-MS Homo sapiens
341 DDOST 1650
Affinity Capture-MS Homo sapiens
342 RTN1 6252
Proximity Label-MS Homo sapiens
343 Ncstn 59287
Affinity Capture-MS Mus musculus
344 PGRMC2 10424
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
345 SVIP 258010
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
346 DNAJC16  
Proximity Label-MS Homo sapiens
347 NGLY1 55768
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
348 SERPINA1 5265
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
349 PPP1R15B  
Proximity Label-MS Homo sapiens
350 RAB35 11021
Proximity Label-MS Homo sapiens
351 FAF2 23197
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
352 FFAR2  
Two-hybrid Homo sapiens
353 POM121C  
Proximity Label-MS Homo sapiens
354 LMNB1 4001
Proximity Label-MS Homo sapiens
355 EMD 2010
Proximity Label-MS Homo sapiens
356 Vcp 269523
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
357 LRIG2  
Proximity Label-MS Homo sapiens
358 Tapt1  
Affinity Capture-MS Mus musculus
359 AGK 55750
Proximity Label-MS Homo sapiens
360 HSP90B1 7184
Affinity Capture-MS Homo sapiens
361 CYB5A 1528
Proximity Label-MS Homo sapiens
362 APOL2 23780
Proximity Label-MS Homo sapiens
363 VCP 7415
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
364 DDX5 1655
Affinity Capture-MS Homo sapiens
365 SUN2 25777
Proximity Label-MS Homo sapiens
366 MLX  
Proximity Label-MS Homo sapiens
367 MIA3 375056
Proximity Label-MS Homo sapiens
368 TRIM32 22954
Two-hybrid Homo sapiens
369 SMC1A 8243
Affinity Capture-MS Homo sapiens
370 PML 5371
Affinity Capture-MS Homo sapiens
371 ATP2B4 493
Proximity Label-MS Homo sapiens
372 SLC33A1 9197
Proximity Label-MS Homo sapiens
373 ACBD3 64746
Proximity Label-MS Homo sapiens
374 SNAP29 9342
Proximity Label-MS Homo sapiens
375 TEX2 55852
Proximity Label-MS Homo sapiens
376 OXA1L  
Proximity Label-MS Homo sapiens
377 SEC63 11231
Proximity Label-MS Homo sapiens
378 PKMYT1  
Proximity Label-MS Homo sapiens
379 GOLGA3 2802
Proximity Label-MS Homo sapiens
380 TMX3 54495
Proximity Label-MS Homo sapiens
381 PANX1 24145
Proximity Label-MS Homo sapiens
382 ATP2B1 490
Proximity Label-MS Homo sapiens
383 HMOX2 3163
Proximity Label-MS Homo sapiens
384 PCDHB15  
Affinity Capture-MS Homo sapiens
385 P2RY2 5029
Affinity Capture-MS Homo sapiens
386 CCDC155  
Two-hybrid Homo sapiens
387 VARS 7407
Affinity Capture-MS Homo sapiens
388 EHBP1 23301
Proximity Label-MS Homo sapiens
389 Vps4b 20479
Affinity Capture-MS Mus musculus
390 FDFT1 2222
Proximity Label-MS Homo sapiens
391 ACSL3 2181
Proximity Label-MS Homo sapiens
392 AKAP5  
Affinity Capture-MS Homo sapiens
393 USP19 10869
Affinity Capture-Western Homo sapiens
394 SIRT2 22933
Proximity Label-MS Homo sapiens
395 FNDC3A 22862
Proximity Label-MS Homo sapiens
396 STBD1 8987
Proximity Label-MS Homo sapiens
397 C2orf57  
Two-hybrid Homo sapiens
398 GGCX 2677
Proximity Label-MS Homo sapiens
399 SEC24B 10427
Proximity Label-MS Homo sapiens
400 LBR 3930
Proximity Label-MS Homo sapiens
401 ADAM17 6868
Proximity Label-MS Homo sapiens
402 USE1 55850
Proximity Label-MS Homo sapiens
403 RRBP1 6238
Proximity Label-MS Homo sapiens
404 C1orf43 25912
Proximity Label-MS Homo sapiens
405 NUP133 55746
Proximity Label-MS Homo sapiens
406 SYAP1 94056
Proximity Label-MS Homo sapiens
407 DNAJA2 10294
Proximity Label-MS Homo sapiens
408 CYP51A1 1595
Proximity Label-MS Homo sapiens
409 TYW1  
Proximity Label-MS Homo sapiens
410 PDE3B  
Proximity Label-MS Homo sapiens
411 NUP35 129401
Proximity Label-MS Homo sapiens
412 ATP2A2 488
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
413 NUP98 4928
Proximity Label-MS Homo sapiens
414 SPTLC2 9517
Proximity Label-MS Homo sapiens
415 FADS2 9415
Proximity Label-MS Homo sapiens
416 NUP107 57122
Proximity Label-MS Homo sapiens
417 CLMN  
Proximity Label-MS Homo sapiens
418 CAD 790
Affinity Capture-MS Homo sapiens
419 SLC27A3 11000
Proximity Label-MS Homo sapiens
420 CYB5R3 1727
Proximity Label-MS Homo sapiens
421 CDK5RAP3 80279
Proximity Label-MS Homo sapiens
422 MOSPD2 158747
Proximity Label-MS Homo sapiens
423 DNAJC1 64215
Proximity Label-MS Homo sapiens
424 GNB2L1 10399
Affinity Capture-MS Homo sapiens
425 CFTR 1080
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
426 ESYT1 23344
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
427 VEZT 55591
Proximity Label-MS Homo sapiens
428 USP20  
Proximity Label-MS Homo sapiens
429 DSG2 1829
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here