Gene description for VDAC1
Gene name voltage-dependent anion channel 1
Gene symbol VDAC1
Other names/aliases PORIN
VDAC-1
Species Homo sapiens
 Database cross references - VDAC1
ExoCarta ExoCarta_7416
Vesiclepedia VP_7416
Entrez Gene 7416
HGNC 12669
MIM 604492
UniProt P21796  
 VDAC1 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
 Gene ontology annotations for VDAC1
Molecular Function
    voltage-gated monoatomic ion channel activity GO:0005244 IDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    oxysterol binding GO:0008142 ISS
    voltage-gated monoatomic anion channel activity GO:0008308 IBA
    voltage-gated monoatomic anion channel activity GO:0008308 IDA
    voltage-gated monoatomic anion channel activity GO:0008308 ISS
    voltage-gated monoatomic anion channel activity GO:0008308 TAS
    porin activity GO:0015288 IEA
    cholesterol binding GO:0015485 IDA
    protein kinase binding GO:0019901 IPI
    phosphatidylcholine binding GO:0031210 IDA
    identical protein binding GO:0042802 IPI
    transmembrane transporter binding GO:0044325 IPI
    ceramide binding GO:0097001 IDA
Biological Process
    behavioral fear response GO:0001662 IEA
    pyruvate metabolic process GO:0006090 TAS
    monoatomic anion transport GO:0006820 IDA
    lipid transport GO:0006869 IEA
    apoptotic process GO:0006915 IDA
    apoptotic process GO:0006915 TAS
    neuron-neuron synaptic transmission GO:0007270 IEA
    learning GO:0007612 IEA
    epithelial cell differentiation GO:0030855 IEP
    calcium import into the mitochondrion GO:0036444 ISS
    positive regulation of apoptotic process GO:0043065 IDA
    negative regulation of apoptotic process GO:0043066 IMP
    monoatomic anion transmembrane transport GO:0098656 IEA
    negative regulation of calcium import into the mitochondrion GO:0110099 IMP
    regulation of autophagy of mitochondrion GO:1903146 NAS
    positive regulation of type 2 mitophagy GO:1905091 IMP
    mitochondrial transmembrane transport GO:1990542 IDA
    negative regulation of reactive oxygen species metabolic process GO:2000378 IEA
Subcellular Localization
    nucleus GO:0005634 HDA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial outer membrane GO:0005741 IBA
    mitochondrial outer membrane GO:0005741 IDA
    mitochondrial outer membrane GO:0005741 TAS
    mitochondrial permeability transition pore complex GO:0005757 IDA
    plasma membrane GO:0005886 IDA
    membrane GO:0016020 IDA
    membrane GO:0016020 ISS
    mitochondrial membrane GO:0031966 IDA
    mitochondrial nucleoid GO:0042645 IDA
    membrane raft GO:0045121 IEA
    synapse GO:0045202 IEA
    pore complex GO:0046930 TAS
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified VDAC1 in sEVs
1
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 236
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
21
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 258
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
25
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 224
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
28
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
41
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 217
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for VDAC1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC25A13 10165
Affinity Capture-MS Homo sapiens
2 SLC1A5 6510
Affinity Capture-MS Homo sapiens
3 RIN3  
Affinity Capture-MS Homo sapiens
4 MCC 4163
Affinity Capture-MS Homo sapiens
5 WDR87  
Cross-Linking-MS (XL-MS) Homo sapiens
6 KIF20A 10112
Affinity Capture-MS Homo sapiens
7 UBC 7316
Affinity Capture-MS Homo sapiens
8 SEPT2 4735
Co-fractionation Homo sapiens
9 Tmem109  
Affinity Capture-MS Mus musculus
10 HAL 3034
Affinity Capture-MS Homo sapiens
11 CKB 1152
Affinity Capture-MS Homo sapiens
12 DARS 1615
Affinity Capture-MS Homo sapiens
13 COX7A2L 9167
Co-fractionation Homo sapiens
14 H2AFV 94239
Affinity Capture-MS Homo sapiens
15 NOP58 51602
Affinity Capture-MS Homo sapiens
16 AI837181  
Affinity Capture-MS Mus musculus
17 CALD1 800
Affinity Capture-MS Homo sapiens
18 SLC9A9 285195
Affinity Capture-MS Homo sapiens
19 ETFA 2108
Affinity Capture-MS Homo sapiens
20 SCARB1 949
Co-fractionation Homo sapiens
21 PPM1A 5494
Affinity Capture-MS Homo sapiens
22 SLC25A46 91137
Proximity Label-MS Homo sapiens
23 MECP2 4204
Affinity Capture-MS Homo sapiens
24 MLEC 9761
Co-fractionation Homo sapiens
25 STX12 23673
Co-fractionation Homo sapiens
26 SLC25A3 5250
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
27 KIF14 9928
Affinity Capture-MS Homo sapiens
28 ATP1A3 478
Co-fractionation Homo sapiens
29 KLF16  
Affinity Capture-MS Homo sapiens
30 CHMP4C 92421
Affinity Capture-MS Homo sapiens
31 MTCH2 23788
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
32 VAV1 7409
Affinity Capture-MS Homo sapiens
33 RAB14 51552
Affinity Capture-MS Homo sapiens
34 TMX1 81542
Co-fractionation Homo sapiens
35 MAPRE1 22919
Affinity Capture-MS Homo sapiens
36 MCAM 4162
Co-fractionation Homo sapiens
37 AKAP1 8165
Proximity Label-MS Homo sapiens
38 UBAC2 337867
Affinity Capture-MS Homo sapiens
39 SLC25A20 788
Co-fractionation Homo sapiens
40 PABPC1 26986
Affinity Capture-MS Homo sapiens
41 EEF1E1 9521
Affinity Capture-MS Homo sapiens
42 CLCC1 23155
Affinity Capture-MS Homo sapiens
43 SAR1B 51128
Affinity Capture-MS Homo sapiens
44 ACADM 34
Co-fractionation Homo sapiens
45 SYNCRIP 10492
Cross-Linking-MS (XL-MS) Homo sapiens
46 BANF1 8815
Affinity Capture-MS Homo sapiens
47 CYC1 1537
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
48 WHSC1L1  
Cross-Linking-MS (XL-MS) Homo sapiens
49 FLOT2 2319
Co-fractionation Homo sapiens
50 VDAC2 7417
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
51 SLC25A5 292
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
52 SSR4 6748
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
53 ANLN 54443
Affinity Capture-MS Homo sapiens
54 CISD1 55847
Co-fractionation Homo sapiens
55 HADHB 3032
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
56 SUGP1  
Co-fractionation Homo sapiens
57 APOE 348
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 LMNB1 4001
Affinity Capture-MS Homo sapiens
59 SIRT7  
Affinity Capture-MS Homo sapiens
60 GOLT1B 51026
Affinity Capture-MS Homo sapiens
61 BCAP31 10134
Co-fractionation Homo sapiens
62 YWHAZ 7534
Affinity Capture-MS Homo sapiens
63 FKBP8 23770
Affinity Capture-MS Homo sapiens
64 MYO19  
Affinity Capture-MS Homo sapiens
65 ATP1B3 483
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
66 EPRS 2058
Affinity Capture-MS Homo sapiens
67 CDC42 998
Cross-Linking-MS (XL-MS) Homo sapiens
68 SOAT1 6646
Affinity Capture-MS Homo sapiens
69 RPA3 6119
Proximity Label-MS Homo sapiens
70 ABCC1 4363
Co-fractionation Homo sapiens
71 PLIN3 10226
Affinity Capture-MS Homo sapiens
72 HSPA4 3308
Affinity Capture-MS Homo sapiens
73 COX2 4513
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
74 SUPT16H 11198
Affinity Capture-MS Homo sapiens
75 SCCPDH 51097
Co-fractionation Homo sapiens
76 STUB1 10273
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
77 HK2 3099
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
78 ATP5J 522
Affinity Capture-MS Homo sapiens
79 FASN 2194
Positive Genetic Homo sapiens
80 CHTOP  
Affinity Capture-MS Homo sapiens
81 RSPRY1 89970
Affinity Capture-MS Homo sapiens
82 COX5A 9377
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 TKT 7086
Affinity Capture-MS Homo sapiens
84 KLHL40  
Two-hybrid Homo sapiens
85 BOLA2 552900
Affinity Capture-MS Homo sapiens
86 SSBP1 6742
Affinity Capture-MS Homo sapiens
87 ATAD3A 55210
Affinity Capture-MS Homo sapiens
88 RUVBL1 8607
Affinity Capture-MS Homo sapiens
89 RAB2A 5862
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
90 BCL2  
Affinity Capture-Western Homo sapiens
91 HIST1H2BF 8343
Affinity Capture-MS Homo sapiens
92 RAB11A 8766
Co-fractionation Homo sapiens
93 CISD2 493856
Co-fractionation Homo sapiens
94 RAB5C 5878
Affinity Capture-MS Homo sapiens
95 ASB14  
Affinity Capture-MS Homo sapiens
96 BST2 684
Co-fractionation Homo sapiens
97 HIST1H2BC 8347
Affinity Capture-MS Homo sapiens
98 LDHA 3939
Affinity Capture-MS Homo sapiens
99 Tmed2 56334
Affinity Capture-MS Mus musculus
100 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
101 SPRTN  
Affinity Capture-MS Homo sapiens
102 RPA2 6118
Proximity Label-MS Homo sapiens
103 ADRB2  
PCA Homo sapiens
104 NOP56 10528
Affinity Capture-MS Homo sapiens
105 NDUFS2 4720
Co-fractionation Homo sapiens
106 SAFB 6294
Affinity Capture-MS Homo sapiens
107 RNPS1 10921
Affinity Capture-MS Homo sapiens
108 OGDH 4967
Co-fractionation Homo sapiens
109 PSMA3 5684
Affinity Capture-MS Homo sapiens
110 RBMXL2  
Affinity Capture-MS Homo sapiens
111 H1FX 8971
Affinity Capture-MS Homo sapiens
112 SPIN1  
Affinity Capture-MS Homo sapiens
113 ABCC3 8714
Co-fractionation Homo sapiens
114 ELOVL1 64834
Affinity Capture-MS Homo sapiens
115 PRC1 9055
Affinity Capture-MS Homo sapiens
116 NDUFA5 4698
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
117 NPM1 4869
Proximity Label-MS Homo sapiens
118 ZFYVE1 53349
Affinity Capture-MS Homo sapiens
119 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 PANK2 80025
Affinity Capture-MS Homo sapiens
121 VCAM1 7412
Affinity Capture-MS Homo sapiens
122 TOMM40 10452
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
123 TIAL1 7073
Co-fractionation Homo sapiens
124 HK1 3098
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
125 ATP5I 521
Co-fractionation Homo sapiens
126 PFN1 5216
Affinity Capture-MS Homo sapiens
127 MAPK3 5595
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
128 HIST1H2BG 8339
Affinity Capture-MS Homo sapiens
129 DDX21 9188
Affinity Capture-MS Homo sapiens
130 NFRKB  
Cross-Linking-MS (XL-MS) Homo sapiens
131 ZNF207 7756
Cross-Linking-MS (XL-MS) Homo sapiens
132 STOM 2040
Affinity Capture-MS Homo sapiens
133 NDUFA8 4702
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
134 RAB19 401409
Co-fractionation Homo sapiens
135 GK  
Affinity Capture-MS Homo sapiens
136 UQCRC1 7384
Affinity Capture-MS Homo sapiens
137 IARS 3376
Affinity Capture-MS Homo sapiens
138 RPLP0P6 220717
Co-fractionation Homo sapiens
139 PRKCE 5581
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
140 RSL1D1 26156
Affinity Capture-MS Homo sapiens
141 FBXL4 26235
Affinity Capture-MS Homo sapiens
142 PER2  
Proximity Label-MS Homo sapiens
143 SGPL1 8879
Co-fractionation Homo sapiens
144 RPN2 6185
Affinity Capture-MS Homo sapiens
145 AIFM1 9131
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 CANX 821
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
147 ICAM1 3383
Co-fractionation Homo sapiens
148 RAB5A 5868
Co-fractionation Homo sapiens
149 UBAP2 55833
Co-fractionation Homo sapiens
150 Rmdn3  
Affinity Capture-MS Mus musculus
151 ATP5F1 515
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
152 LARS 51520
Affinity Capture-MS Homo sapiens
153 SCYL2 55681
Affinity Capture-MS Homo sapiens
154 CDK2 1017
Affinity Capture-MS Homo sapiens
155 TPM1 7168
Affinity Capture-MS Homo sapiens
156 MYC  
Proximity Label-MS Homo sapiens
157 SLC3A2 6520
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
158 MOGS 7841
Co-fractionation Homo sapiens
159 Park2  
Biochemical Activity Rattus norvegicus
160 ACAD9 28976
Co-fractionation Homo sapiens
161 RCN2 5955
Affinity Capture-MS Homo sapiens
162 DDRGK1 65992
Affinity Capture-MS Homo sapiens
163 NDUFV2 4729
Affinity Capture-MS Homo sapiens
164 TOMM20 9804
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
165 EEF1A1 1915
Co-fractionation Homo sapiens
166 ATP1A2 477
Co-fractionation Homo sapiens
167 SURF6  
Affinity Capture-MS Homo sapiens
168 HMGB1 3146
Cross-Linking-MS (XL-MS) Homo sapiens
169 PGRMC1 10857
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
170 MEST 4232
Co-fractionation Homo sapiens
171 SEC11A 23478
Cross-Linking-MS (XL-MS) Homo sapiens
172 MCL1 4170
Reconstituted Complex Homo sapiens
173 EZR 7430
Co-fractionation Homo sapiens
174 VWA9  
Affinity Capture-MS Homo sapiens
175 SQSTM1 8878
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
176 Htt  
Affinity Capture-MS Mus musculus
177 CDK1 983
Affinity Capture-MS Homo sapiens
178 MMGT1 93380
Affinity Capture-MS Homo sapiens
179 DCD 117159
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 ATP5J2 9551
Affinity Capture-MS Homo sapiens
181 PPM1B 5495
Affinity Capture-MS Homo sapiens
182 BCL2L1 598
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
183 ATP1A1 476
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
184 ARF1 375
Affinity Capture-MS Homo sapiens
185 ATP5C1 509
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
186 CYCS 54205
Co-purification Homo sapiens
187 CKAP4 10970
Co-fractionation Homo sapiens
188 RNF139  
Affinity Capture-MS Homo sapiens
189 NDUFB4 4710
Co-fractionation Homo sapiens
190 ATAD1 84896
Affinity Capture-MS Homo sapiens
191 CBX1 10951
Affinity Capture-MS Homo sapiens
192 AGPAT5 55326
Affinity Capture-MS Homo sapiens
193 MTCH1 23787
Co-fractionation Homo sapiens
194 RAB1A 5861
Affinity Capture-MS Homo sapiens
195 EEF1G 1937
Affinity Capture-MS Homo sapiens
196 NDUFS1 4719
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
197 ABCA13  
Cross-Linking-MS (XL-MS) Homo sapiens
198 YWHAE 7531
Affinity Capture-MS Homo sapiens
199 CD4 920
Affinity Capture-MS Homo sapiens
200 BOLA2B 654483
Affinity Capture-MS Homo sapiens
201 PRPH 5630
Affinity Capture-MS Homo sapiens
202 UQCRB 7381
Co-fractionation Homo sapiens
203 SSB 6741
Affinity Capture-MS Homo sapiens
204 RTN4 57142
Affinity Capture-MS Homo sapiens
205 NDUFB9 4715
Co-fractionation Homo sapiens
206 PLOD3 8985
Co-fractionation Homo sapiens
207 NDUFS3 4722
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
208 MOB2 81532
Affinity Capture-MS Homo sapiens
209 MDC1  
Affinity Capture-MS Homo sapiens
210 BCAP29 55973
Co-fractionation Homo sapiens
211 NDUFV1 4723
Co-fractionation Homo sapiens
212 ALCAM 214
Co-fractionation Homo sapiens
213 CSNK2B 1460
Two-hybrid Homo sapiens
214 NDUFS5 4725
Co-fractionation Homo sapiens
215 MTERF3  
Proximity Label-MS Homo sapiens
216 HSPA8 3312
Affinity Capture-Western Homo sapiens
217 BSG 682
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
218 RPL27 6155
Affinity Capture-MS Homo sapiens
219 ATP5A1 498
Co-fractionation Homo sapiens
220 SAMM50 25813
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
221 BCL2L11  
Affinity Capture-Western Homo sapiens
222 ALDH5A1 7915
Co-fractionation Homo sapiens
223 C17orf75 64149
Co-fractionation Homo sapiens
224 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
225 COPE 11316
Affinity Capture-MS Homo sapiens
226 CHCHD3 54927
Affinity Capture-MS Homo sapiens
227 TUBA1A 7846
Co-fractionation Homo sapiens
228 CBX3 11335
Affinity Capture-MS Homo sapiens
229 ACACA 31
Affinity Capture-MS Homo sapiens
230 TUBA1B 10376
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
231 PIP5K1C  
Affinity Capture-MS Homo sapiens
232 NTRK1 4914
Affinity Capture-MS Homo sapiens
233 TPI1 7167
Affinity Capture-MS Homo sapiens
234 U2AF2 11338
Affinity Capture-MS Homo sapiens
235 RPL36 25873
Affinity Capture-MS Homo sapiens
236 OCIAD2 132299
Co-fractionation Homo sapiens
237 IGSF10 285313
Cross-Linking-MS (XL-MS) Homo sapiens
238 RPN1 6184
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
239 CHMP4B 128866
Affinity Capture-MS Homo sapiens
240 TECR 9524
Co-fractionation Homo sapiens
241 SAFB2 9667
Affinity Capture-MS Homo sapiens
242 HDAC5 10014
Affinity Capture-MS Homo sapiens
243 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
244 Rab5c 19345
Affinity Capture-MS Mus musculus
245 ZBTB2 57621
Affinity Capture-MS Homo sapiens
246 METTL14  
Affinity Capture-MS Homo sapiens
247 ECT2 1894
Affinity Capture-MS Homo sapiens
248 EEF2 1938
Affinity Capture-MS Homo sapiens
249 HRNR 388697
Affinity Capture-MS Homo sapiens
250 LMNB2 84823
Affinity Capture-MS Homo sapiens
251 TRAF6 7189
Affinity Capture-MS Homo sapiens
252 SF1 7536
Co-fractionation Homo sapiens
253 NR3C1 2908
Affinity Capture-Western Homo sapiens
254 H1F0 3005
Affinity Capture-MS Homo sapiens
255 CORO1C 23603
Co-fractionation Homo sapiens
256 OCIAD1 54940
Proximity Label-MS Homo sapiens
257 CUL9  
Co-fractionation Homo sapiens
258 GNB2 2783
Co-fractionation Homo sapiens
259 TOP1 7150
Affinity Capture-MS Homo sapiens
260 RPL12 6136
Affinity Capture-MS Homo sapiens
261 HP1BP3 50809
Affinity Capture-MS Homo sapiens
262 RAF1 5894
Affinity Capture-Western Homo sapiens
263 ACTB 60
Co-fractionation Homo sapiens
264 RANBP1 5902
Cross-Linking-MS (XL-MS) Homo sapiens
265 GALNT2 2590
Co-fractionation Homo sapiens
266 HSPD1 3329
Co-fractionation Homo sapiens
267 HIST1H2BI 8346
Affinity Capture-MS Homo sapiens
268 MAGT1 84061
Co-fractionation Homo sapiens
269 XRCC5 7520
Affinity Capture-MS Homo sapiens
270 TPM3 7170
Affinity Capture-MS Homo sapiens
271 AQP9  
Co-fractionation Homo sapiens
272 IMMT 10989
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
273 TUBB2A 7280
Co-fractionation Homo sapiens
274 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
275 PHB2 11331
Co-fractionation Homo sapiens
276 CCT8 10694
Affinity Capture-MS Homo sapiens
277 SLC25A6 293
Affinity Capture-MS Homo sapiens
278 FBXL6  
Affinity Capture-MS Homo sapiens
279 TOMM22 56993
Affinity Capture-MS Homo sapiens
280 ERLIN1 10613
Affinity Capture-MS Homo sapiens
281 ICT1 3396
Affinity Capture-MS Homo sapiens
282 ACAA2 10449
Co-fractionation Homo sapiens
283 PDHA1 5160
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
284 GABARAPL2 11345
Affinity Capture-MS Homo sapiens
285 THRAP3 9967
Affinity Capture-MS Homo sapiens
286 ERLIN2 11160
Affinity Capture-MS Homo sapiens
287 PLOD1 5351
Co-fractionation Homo sapiens
288 GNB1 2782
Co-fractionation Homo sapiens
289 MYL12A 10627
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
290 PGAM2 5224
Affinity Capture-MS Homo sapiens
291 TRAP1 10131
Affinity Capture-MS Homo sapiens
292 NDUFS8 4728
Co-fractionation Homo sapiens
293 FGFR1OP2  
Affinity Capture-MS Homo sapiens
294 RTCB 51493
Affinity Capture-MS Homo sapiens
295 PRDX6 9588
Affinity Capture-MS Homo sapiens
296 RAB7A 7879
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
297 ZG16B 124220
Affinity Capture-MS Homo sapiens
298 CIT 11113
Affinity Capture-MS Homo sapiens
299 RPL28 6158
Affinity Capture-MS Homo sapiens
300 COX7C 1350
Co-fractionation Homo sapiens
301 AR 367
Affinity Capture-MS Homo sapiens
302 VDAC3 7419
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
303 SSRP1 6749
Affinity Capture-MS Homo sapiens
304 CAV1 857
Affinity Capture-Western Homo sapiens
305 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
306 DPY19L1 23333
Affinity Capture-MS Homo sapiens
307 FMNL1 752
Affinity Capture-MS Homo sapiens
308 RFTN1 23180
Co-fractionation Homo sapiens
309 Mtx2  
Affinity Capture-MS Mus musculus
310 VAPA 9218
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
311 RPL30 6156
Affinity Capture-MS Homo sapiens
312 KPNB1 3837
Affinity Capture-MS Homo sapiens
313 PPIA 5478
Affinity Capture-MS Homo sapiens
314 PDHB 5162
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
315 ILF2 3608
Affinity Capture-MS Homo sapiens
316 ASB17  
Affinity Capture-MS Homo sapiens
317 TSPO 706
Co-fractionation Homo sapiens
318 TOP2A 7153
Affinity Capture-MS Homo sapiens
319 ATP5D 513
Co-fractionation Homo sapiens
320 PRDX3 10935
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
321 KLF8  
Affinity Capture-MS Homo sapiens
322 KIF5B 3799
Affinity Capture-MS Homo sapiens
323 IMPDH2 3615
Affinity Capture-MS Homo sapiens
324 MRPL12 6182
Affinity Capture-MS Homo sapiens
325 DDOST 1650
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
326 HADHA 3030
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
327 ATP5O 539
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
328 SERPINH1 871
Affinity Capture-MS Homo sapiens
329 ATP6V0D1 9114
Co-fractionation Homo sapiens
330 ATP5H 10476
Affinity Capture-MS Homo sapiens
331 SSR3 6747
Co-fractionation Homo sapiens
332 RAB1B 81876
Affinity Capture-MS Homo sapiens
333 MAPK1 5594
Co-localization Homo sapiens
334 DHCR7 1717
Co-fractionation Homo sapiens
335 NDUFS4 4724
Co-fractionation Homo sapiens
336 COX15 1355
Affinity Capture-MS Homo sapiens
337 MGAT4B 11282
Co-fractionation Homo sapiens
338 EMD 2010
Affinity Capture-MS Homo sapiens
339 SFXN3 81855
Co-fractionation Homo sapiens
340 HSP90B1 7184
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
341 GPR35  
Affinity Capture-MS Homo sapiens
342 ATF2  
Affinity Capture-Western Homo sapiens
343 USMG5 84833
Co-fractionation Homo sapiens
344 AHNAK 79026
Cross-Linking-MS (XL-MS) Homo sapiens
345 ZMPSTE24 10269
Co-fractionation Homo sapiens
346 SF3B6 51639
Affinity Capture-MS Homo sapiens
347 MYH11 4629
Affinity Capture-MS Homo sapiens
348 H2AFY 9555
Affinity Capture-MS Homo sapiens
349 NIPSNAP1 8508
Co-fractionation Homo sapiens
350 AASDHPPT 60496
Cross-Linking-MS (XL-MS) Homo sapiens
351 ATP5B 506
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
352 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
353 COX4I1 1327
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
354 BAG3 9531
Affinity Capture-MS Homo sapiens
355 PHB 5245
Co-fractionation Homo sapiens
356 PLAT 5327
Reconstituted Complex Homo sapiens
357 BAX 581
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
358 FANCD2  
Affinity Capture-MS Homo sapiens
359 GNB4 59345
Co-fractionation Homo sapiens
360 NDUFB10 4716
Co-fractionation Homo sapiens
361 NDUFA9 4704
Co-fractionation Homo sapiens
362 ATP2B1 490
Co-fractionation Homo sapiens
363 RPL35 11224
Affinity Capture-MS Homo sapiens
364 UQCRC2 7385
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
365 NME2 4831
Affinity Capture-MS Homo sapiens
366 DAD1 1603
Co-fractionation Homo sapiens
367 CYB5R3 1727
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
368 TXN 7295
Affinity Capture-MS Homo sapiens
369 HDHD2 84064
Cross-Linking-MS (XL-MS) Homo sapiens
370 NAP1L1 4673
Affinity Capture-MS Homo sapiens
371 NXF1 10482
Affinity Capture-RNA Homo sapiens
372 PRKACA 5566
Affinity Capture-MS Homo sapiens
373 MAPK6  
Affinity Capture-MS Homo sapiens
374 GPCPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
375 DKC1 1736
Affinity Capture-MS Homo sapiens
376 FBL 2091
Affinity Capture-MS Homo sapiens
377 MYOF 26509
Co-fractionation Homo sapiens
378 DNAJC9 23234
Affinity Capture-MS Homo sapiens
379 ATP6V1A 523
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
380 ATP1B1 481
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
381 Haus3  
Affinity Capture-MS Mus musculus
382 FGFR1 2260
Affinity Capture-MS Homo sapiens
383 CLTC 1213
Co-fractionation Homo sapiens
384 GSN 2934
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
385 SNCA 6622
Affinity Capture-Western Homo sapiens
386 SLC25A11 8402
Co-fractionation Homo sapiens
387 SPTAN1 6709
Co-fractionation Homo sapiens
388 FOXRED2  
Affinity Capture-MS Homo sapiens
389 ERH 2079
Affinity Capture-MS Homo sapiens
390 Aifm1  
Affinity Capture-MS Mus musculus
391 SAP18 10284
Affinity Capture-MS Homo sapiens
392 UBA52 7311
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
393 GPX4 2879
Co-fractionation Homo sapiens
394 ELAVL1 1994
Affinity Capture-MS Homo sapiens
395 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
396 ATP2A2 488
Co-fractionation Homo sapiens
397 STOML2 30968
Affinity Capture-MS Homo sapiens
398 SFXN1 94081
Affinity Capture-MS Homo sapiens
399 ITGAV 3685
Co-fractionation Homo sapiens
400 KIAA1429 25962
Affinity Capture-MS Homo sapiens
401 MOV10 4343
Affinity Capture-RNA Homo sapiens
402 SLC25A4 291
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
403 TRIM31  
Affinity Capture-MS Homo sapiens
404 PINK1  
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
405 COX7A2 1347
Affinity Capture-MS Homo sapiens
406 BAG5 9529
Affinity Capture-MS Homo sapiens
407 XRCC6 2547
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
408 C9orf72  
Affinity Capture-MS Homo sapiens
409 PAF1 54623
Affinity Capture-MS Homo sapiens
410 UFM1 51569
Co-fractionation Homo sapiens
411 FLG2 388698
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here