Gene description for PRDX3
Gene name peroxiredoxin 3
Gene symbol PRDX3
Other names/aliases AOP-1
AOP1
HBC189
MER5
PRO1748
SP-22
prx-III
Species Homo sapiens
 Database cross references - PRDX3
ExoCarta ExoCarta_10935
Vesiclepedia VP_10935
Entrez Gene 10935
HGNC 9354
MIM 604769
UniProt P30048  
 PRDX3 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 17956143    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
 Gene ontology annotations for PRDX3
Molecular Function
    protein binding GO:0005515 IPI
    thioredoxin peroxidase activity GO:0008379 IBA
    thioredoxin peroxidase activity GO:0008379 IDA
    protein kinase binding GO:0019901 IPI
    identical protein binding GO:0042802 IPI
    cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027 IMP
    NADH-dependent peroxiredoxin activity GO:0102039 NAS
Biological Process
    maternal placenta development GO:0001893 IEA
    response to oxidative stress GO:0006979 IBA
    response to oxidative stress GO:0006979 IMP
    mitochondrion organization GO:0007005 IMP
    positive regulation of cell population proliferation GO:0008284 IDA
    peptidyl-cysteine oxidation GO:0018171 IDA
    myeloid cell differentiation GO:0030099 ISS
    response to lipopolysaccharide GO:0032496 ISS
    negative regulation of kinase activity GO:0033673 IDA
    cellular response to oxidative stress GO:0034599 IDA
    cellular response to reactive oxygen species GO:0034614 IMP
    response to hydrogen peroxide GO:0042542 IDA
    hydrogen peroxide catabolic process GO:0042744 IBA
    hydrogen peroxide catabolic process GO:0042744 IDA
    hydrogen peroxide catabolic process GO:0042744 IMP
    negative regulation of apoptotic process GO:0043066 IDA
    negative regulation of apoptotic process GO:0043066 IMP
    cell redox homeostasis GO:0045454 IBA
    positive regulation of NF-kappaB transcription factor activity GO:0051092 IDA
    regulation of mitochondrial membrane potential GO:0051881 IMP
    cellular oxidant detoxification GO:0098869 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 TAS
    early endosome GO:0005769 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
    protein-containing complex GO:0032991 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified PRDX3 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
17
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for PRDX3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 COL6A1 1291
Co-fractionation Homo sapiens
3 KLF8  
Affinity Capture-MS Homo sapiens
4 XIAP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 PTMS 5763
Affinity Capture-MS Homo sapiens
6 QARS 5859
Co-fractionation Homo sapiens
7 RAB1A 5861
Co-fractionation Homo sapiens
8 HSPA6 3310
Co-fractionation Homo sapiens
9 ARHGAP39  
Affinity Capture-MS Homo sapiens
10 SPATA7 55812
Co-fractionation Homo sapiens
11 SMC6  
Affinity Capture-MS Homo sapiens
12 DAG1 1605
Co-fractionation Homo sapiens
13 PSMA4 5685
Co-fractionation Homo sapiens
14 RPA2 6118
Proximity Label-MS Homo sapiens
15 CAP1 10487
Co-fractionation Homo sapiens
16 APOE 348
Co-fractionation Homo sapiens
17 SSB 6741
Co-fractionation Homo sapiens
18 CALM1 801
Affinity Capture-MS Homo sapiens
19 LNPEP 4012
Co-fractionation Homo sapiens
20 RPUSD4 84881
Proximity Label-MS Homo sapiens
21 KDM4A  
Affinity Capture-MS Homo sapiens
22 PARK7 11315
Affinity Capture-MS Homo sapiens
23 SF3B2 10992
Co-fractionation Homo sapiens
24 ATP5L 10632
Co-fractionation Homo sapiens
25 MGST1 4257
Co-fractionation Homo sapiens
26 MARK2 2011
Affinity Capture-MS Homo sapiens
27 PFKL 5211
Co-fractionation Homo sapiens
28 OGDH 4967
Co-fractionation Homo sapiens
29 PRDX3 10935
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
30 PMPCA 23203
Proximity Label-MS Homo sapiens
31 MCM2 4171
Affinity Capture-MS Homo sapiens
32 CYB5R1 51706
Co-fractionation Homo sapiens
33 HYOU1 10525
Co-fractionation Homo sapiens
34 STMN1 3925
Affinity Capture-MS Homo sapiens
35 ANP32B 10541
Affinity Capture-MS Homo sapiens
36 COPS5 10987
Affinity Capture-MS Homo sapiens
37 FBXW7  
Affinity Capture-MS Homo sapiens
38 POU5F1  
Affinity Capture-MS Homo sapiens
39 BASP1 10409
Affinity Capture-MS Homo sapiens
40 ARMCX3 51566
Co-fractionation Homo sapiens
41 PSME1 5720
Co-fractionation Homo sapiens
42 PRDX2 7001
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
43 MRPS26 64949
Proximity Label-MS Homo sapiens
44 ATP5O 539
Co-fractionation Homo sapiens
45 ITGA4 3676
Affinity Capture-MS Homo sapiens
46 NUSAP1 51203
Co-fractionation Homo sapiens
47 UCHL5 51377
Affinity Capture-MS Homo sapiens
48 HMGCLL1  
Co-fractionation Homo sapiens
49 VCAM1 7412
Affinity Capture-MS Homo sapiens
50 PRDX4 10549
Two-hybrid Homo sapiens
51 CANX 821
Affinity Capture-MS Homo sapiens
52 CALR 811
Affinity Capture-MS Homo sapiens
53 MECP2 4204
Affinity Capture-MS Homo sapiens
54 CUL1 8454
Affinity Capture-MS Homo sapiens
55 TFCP2 7024
Affinity Capture-MS Homo sapiens
56 ARIH2 10425
Affinity Capture-MS Homo sapiens
57 UBQLN4 56893
Co-fractionation Homo sapiens
58 VWA8 23078
Proximity Label-MS Homo sapiens
59 NEDD4 4734
Affinity Capture-MS Homo sapiens
60 ARHGAP9 64333
Affinity Capture-MS Homo sapiens
61 PABPC4 8761
Co-fractionation Homo sapiens
62 OBSL1 23363
Affinity Capture-MS Homo sapiens
63 SLC25A3 5250
Co-fractionation Homo sapiens
64 DOCK8 81704
Affinity Capture-MS Homo sapiens
65 SFXN1 94081
Co-fractionation Homo sapiens
66 PRNP 5621
Affinity Capture-MS Homo sapiens
67 YWHAB 7529
Affinity Capture-MS Homo sapiens
68 MDH2 4191
Proximity Label-MS Homo sapiens
69 GTF2I 2969
Co-fractionation Homo sapiens
70 UNK  
Affinity Capture-RNA Homo sapiens
71 PFN1 5216
Affinity Capture-MS Homo sapiens
72 CHMP4C 92421
Affinity Capture-MS Homo sapiens
73 ARHGEF10 9639
Affinity Capture-MS Homo sapiens
74 DLD 1738
Affinity Capture-MS Homo sapiens
75 EIF6 3692
Affinity Capture-MS Homo sapiens
76 ATP5A1 498
Co-fractionation Homo sapiens
77 PGAM1 5223
Affinity Capture-MS Homo sapiens
78 C6orf203  
Proximity Label-MS Homo sapiens
79 MAPK3 5595
Affinity Capture-MS Homo sapiens
80 Gtf3c4  
Affinity Capture-MS Mus musculus
81 COX15 1355
Affinity Capture-MS Homo sapiens
82 ZFYVE16  
Proximity Label-MS Homo sapiens
83 CUL4B 8450
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
84 COPE 11316
Affinity Capture-MS Homo sapiens
85 SNRPA 6626
Co-fractionation Homo sapiens
86 NDUFA8 4702
Co-fractionation Homo sapiens
87 NLRX1 79671
Affinity Capture-MS Homo sapiens
88 TUFM 7284
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
89 Spred2  
Affinity Capture-MS Mus musculus
90 CCNB1 891
Affinity Capture-MS Homo sapiens
91 PABPC1 26986
Co-fractionation Homo sapiens
92 MAP3K13 9175
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
93 FANCG 2189
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
94 YAP1 10413
Affinity Capture-MS Homo sapiens
95 VCP 7415
Affinity Capture-MS Homo sapiens
96 DDX5 1655
Co-fractionation Homo sapiens
97 Inpp5b  
Affinity Capture-MS Mus musculus
98 PTP4A2 8073
Affinity Capture-MS Homo sapiens
99 GORASP2 26003
Two-hybrid Homo sapiens
100 OPA1 4976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 SLX4  
Affinity Capture-MS Homo sapiens
102 SUMO2 6613
Affinity Capture-MS Homo sapiens
103 TBRG4 9238
Proximity Label-MS Homo sapiens
104 FLNB 2317
Co-fractionation Homo sapiens
105 ACTB 60
Co-fractionation Homo sapiens
106 ARHGEF6 9459
Affinity Capture-MS Homo sapiens
107 LACTB 114294
Affinity Capture-MS Homo sapiens
108 NELFE 7936
Affinity Capture-MS Homo sapiens
109 CUL2 8453
Affinity Capture-MS Homo sapiens
110 AGPS 8540
Co-fractionation Homo sapiens
111 NCL 4691
Co-fractionation Homo sapiens
112 HDAC5 10014
Affinity Capture-MS Homo sapiens
113 ZNF77  
Two-hybrid Homo sapiens
114 ATP5B 506
Co-fractionation Homo sapiens
115 DNAJB11 51726
Co-fractionation Homo sapiens
116 CNR2  
Affinity Capture-MS Homo sapiens
117 HMGB2 3148
Affinity Capture-MS Homo sapiens
118 RPL11 6135
Affinity Capture-MS Homo sapiens
119 MAT2A 4144
Co-fractionation Homo sapiens
120 TPR 7175
Co-fractionation Homo sapiens
121 TRIM21 6737
Affinity Capture-MS Homo sapiens
122 BIRC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 HNRNPD 3184
Two-hybrid Homo sapiens
124 HSPA5 3309
Co-fractionation Homo sapiens
125 AP1S1 1174
Co-fractionation Homo sapiens
126 HADHB 3032
Co-fractionation Homo sapiens
127 HADHA 3030
Co-fractionation Homo sapiens
128 Cd2ap 12488
Affinity Capture-MS Mus musculus
129 METTL14  
Affinity Capture-MS Homo sapiens
130 MTIF2 4528
Proximity Label-MS Homo sapiens
131 ICAM1 3383
Co-fractionation Homo sapiens
132 TIPRL 261726
Co-fractionation Homo sapiens
133 LRRC59 55379
Co-fractionation Homo sapiens
134 SDHA 6389
Affinity Capture-MS Homo sapiens
135 MAGEA11  
Two-hybrid Homo sapiens
136 UQCRC2 7385
Co-fractionation Homo sapiens
137 GGH 8836
Affinity Capture-MS Homo sapiens
138 EEF2 1938
Co-fractionation Homo sapiens
139 PPIB 5479
Affinity Capture-MS Homo sapiens
140 PRKAR1A 5573
Co-fractionation Homo sapiens
141 CD274 29126
Affinity Capture-MS Homo sapiens
142 CS 1431
Proximity Label-MS Homo sapiens
143 TNFRSF1A 7132
Two-hybrid Homo sapiens
144 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 CIT 11113
Affinity Capture-MS Homo sapiens
146 TXN 7295
Co-fractionation Homo sapiens
147 PDIA3 2923
Co-fractionation Homo sapiens
148 KARS 3735
Co-fractionation Homo sapiens
149 HSD17B10 3028
Affinity Capture-MS Homo sapiens
150 EPRS 2058
Co-fractionation Homo sapiens
151 MYC  
Affinity Capture-MS Homo sapiens
152 RIPK4  
Affinity Capture-MS Homo sapiens
153 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
154 POLR3E 55718
Affinity Capture-MS Homo sapiens
155 FN1 2335
Affinity Capture-MS Homo sapiens
156 TCEB1 6921
Co-fractionation Homo sapiens
157 Max  
Affinity Capture-MS Mus musculus
158 CDC42 998
Affinity Capture-MS Homo sapiens
159 DUSP13  
Affinity Capture-MS Homo sapiens
160 CYP51A1 1595
Co-fractionation Homo sapiens
161 CDK2 1017
Affinity Capture-MS Homo sapiens
162 SOAT1 6646
Affinity Capture-MS Homo sapiens
163 ZMYM6  
Affinity Capture-MS Homo sapiens
164 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
165 SPEN 23013
Co-fractionation Homo sapiens
166 BAG1 573
Affinity Capture-MS Homo sapiens
167 DLST 1743
Affinity Capture-MS Homo sapiens
168 TSFM 10102
Proximity Label-MS Homo sapiens
169 Stard13  
Affinity Capture-MS Mus musculus
170 PEBP1 5037
Affinity Capture-MS Homo sapiens
171 HSPA4 3308
Co-fractionation Homo sapiens
172 MYCN  
Affinity Capture-MS Homo sapiens
173 PSMB5 5693
Co-fractionation Homo sapiens
174 DDRGK1 65992
Affinity Capture-MS Homo sapiens
175 NDUFA3  
Co-fractionation Homo sapiens
176 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
177 RNASET2  
Co-fractionation Homo sapiens
178 HSPD1 3329
Co-fractionation Homo sapiens
179 HSPA9 3313
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
180 RARS 5917
Co-fractionation Homo sapiens
181 ARHGAP31 57514
Affinity Capture-MS Homo sapiens
182 ARHGEF15  
Affinity Capture-MS Homo sapiens
183 Psmd6 66413
Affinity Capture-MS Mus musculus
184 PSMB1 5689
Co-fractionation Homo sapiens
185 MCUR1 63933
Proximity Label-MS Homo sapiens
186 SCCPDH 51097
Co-fractionation Homo sapiens
187 H2AFX 3014
Affinity Capture-MS Homo sapiens
188 LARS 51520
Co-fractionation Homo sapiens
189 KRT18 3875
Co-fractionation Homo sapiens
190 STARD8  
Affinity Capture-MS Homo sapiens
191 SNCA 6622
Affinity Capture-MS Homo sapiens
192 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
193 PLS1 5357
Affinity Capture-MS Homo sapiens
194 TERF2  
Affinity Capture-MS Homo sapiens
195 AUH 549
Proximity Label-MS Homo sapiens
196 PARP1 142
Proximity Label-MS Homo sapiens
197 BKRF1  
Affinity Capture-MS
198 GARS 2617
Co-fractionation Homo sapiens
199 ILF3 3609
Co-fractionation Homo sapiens
200 ATP5J 522
Co-fractionation Homo sapiens
201 FANCC 2176
Two-hybrid Homo sapiens
202 UBA5 79876
Affinity Capture-MS Homo sapiens
203 NEK6 10783
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
204 HSPA8 3312
Co-fractionation Homo sapiens
205 ICT1 3396
Proximity Label-MS Homo sapiens
206 PDIA4 9601
Affinity Capture-MS Homo sapiens
207 Msn 17698
Affinity Capture-MS Mus musculus
208 HSD17B4 3295
Co-fractionation Homo sapiens
209 CUL5 8065
Affinity Capture-MS Homo sapiens
210 PDHA1 5160
Proximity Label-MS Homo sapiens
211 NHLRC2 374354
Affinity Capture-MS Homo sapiens
212 CPPED1 55313
Co-fractionation Homo sapiens
213 FKBP4 2288
Co-fractionation Homo sapiens
214 AP1S2 8905
Co-fractionation Homo sapiens
215 PPA1 5464
Co-fractionation Homo sapiens
216 C21orf33  
Proximity Label-MS Homo sapiens
217 GNG5 2787
Co-fractionation Homo sapiens
218 KLF16  
Affinity Capture-MS Homo sapiens
219 PMPCB 9512
Proximity Label-MS Homo sapiens
220 PCNA 5111
Affinity Capture-MS Homo sapiens
221 UFL1 23376
Affinity Capture-MS Homo sapiens
222 GSTM3 2947
Co-fractionation Homo sapiens
223 ANXA11 311
Affinity Capture-MS Homo sapiens
224 Samm50  
Affinity Capture-MS Mus musculus
225 GFM1 85476
Proximity Label-MS Homo sapiens
226 SLC25A4 291
Co-fractionation Homo sapiens
227 RAB7A 7879
Co-fractionation Homo sapiens
228 RPUSD3  
Proximity Label-MS Homo sapiens
229 PRDX1 5052
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
230 CYB5R3 1727
Co-fractionation Homo sapiens
231 DHRS4 10901
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
232 C1QBP 708
Proximity Label-MS Homo sapiens
233 RPS6KC1  
Two-hybrid Homo sapiens
234 CUL7 9820
Affinity Capture-MS Homo sapiens
235 ARHGAP23 57636
Affinity Capture-MS Homo sapiens
236 CARS 833
Co-fractionation Homo sapiens
237 ARHGAP24  
Affinity Capture-MS Homo sapiens
238 METTL17  
Proximity Label-MS Homo sapiens
239 ATXN3 4287
Affinity Capture-MS Homo sapiens
240 NUCKS1 64710
Co-fractionation Homo sapiens
241 PARD6A  
Affinity Capture-MS Homo sapiens
242 IKBKB 3551
Affinity Capture-Western Homo sapiens
243 RPA3 6119
Proximity Label-MS Homo sapiens
244 Cdc26  
Affinity Capture-MS Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here