Gene description for VPS13D
Gene name vacuolar protein sorting 13 homolog D (S. cerevisiae)
Gene symbol VPS13D
Other names/aliases -
Species Homo sapiens
 Database cross references - VPS13D
ExoCarta ExoCarta_55187
Vesiclepedia VP_55187
Entrez Gene 55187
HGNC 23595
MIM 608877
UniProt Q5THJ4  
 VPS13D identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for VPS13D
Biological Process
    protein targeting to vacuole GO:0006623 IBA
    lipid transport GO:0006869 IEA
    mitochondrion organization GO:0007005 IBA
    mitochondrion organization GO:0007005 IMP
    protein retention in Golgi apparatus GO:0045053 IBA
    positive regulation of mitophagy GO:1901526 IMP
Subcellular Localization
    mitochondrion GO:0005739 HTP
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified VPS13D in exosomes
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for VPS13D
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YWHAH 7533
Affinity Capture-MS Homo sapiens
2 RAB3B 5865
Proximity Label-MS Homo sapiens
3 MAVS 57506
Proximity Label-MS Homo sapiens
4 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
5 PHB2 11331
Cross-Linking-MS (XL-MS) Homo sapiens
6 MTCH1 23787
Proximity Label-MS Homo sapiens
7 BAG2 9532
Affinity Capture-MS Homo sapiens
8 AIFM1 9131
Proximity Label-MS Homo sapiens
9 RAB7A 7879
Proximity Label-MS Homo sapiens
10 YWHAB 7529
Affinity Capture-MS Homo sapiens
11 NUP155 9631
Proximity Label-MS Homo sapiens
12 MTX2 10651
Proximity Label-MS Homo sapiens
13 MTCH2 23788
Proximity Label-MS Homo sapiens
14 TSG101 7251
Affinity Capture-Western Homo sapiens
15 MADD 8567
Two-hybrid Homo sapiens
16 YWHAZ 7534
Affinity Capture-MS Homo sapiens
17 NIPAL1  
Affinity Capture-MS Homo sapiens
18 FKBP8 23770
Proximity Label-MS Homo sapiens
19 CALM1 801
Affinity Capture-MS Homo sapiens
20 GBA 2629
Affinity Capture-MS Homo sapiens
21 PTPN1 5770
Proximity Label-MS Homo sapiens
22 RBMX 27316
Cross-Linking-MS (XL-MS) Homo sapiens
23 PSMC1 5700
Co-fractionation Homo sapiens
24 OCIAD1 54940
Proximity Label-MS Homo sapiens
25 PSMD14 10213
Affinity Capture-MS Homo sapiens
26 ESR1  
Affinity Capture-MS Homo sapiens
27 RAB4A 5867
Proximity Label-MS Homo sapiens
28 PXMP2  
Proximity Label-MS Homo sapiens
29 FIS1 51024
Proximity Label-MS Homo sapiens
30 PPP2R1A 5518
Co-fractionation Homo sapiens
31 VCP 7415
Affinity Capture-Western Homo sapiens
32 EGFR 1956
Negative Genetic Homo sapiens
33 RAB9A 9367
Proximity Label-MS Homo sapiens
34 PEX14 5195
Proximity Label-MS Homo sapiens
35 YWHAQ 10971
Affinity Capture-MS Homo sapiens
36 MFN2 9927
Proximity Label-MS Homo sapiens
37 KRAS 3845
Negative Genetic Homo sapiens
38 TMEM31  
Affinity Capture-MS Homo sapiens
39 YWHAG 7532
Affinity Capture-MS Homo sapiens
40 MARCH5  
Proximity Label-MS Homo sapiens
41 PEX3 8504
Proximity Label-MS Homo sapiens
42 RHOT2 89941
Proximity Label-MS Homo sapiens
43 AKAP1 8165
Proximity Label-MS Homo sapiens
44 ATP5B 506
Cross-Linking-MS (XL-MS) Homo sapiens
45 EXD2  
Proximity Label-MS Homo sapiens
46 RMDN3 55177
Proximity Label-MS Homo sapiens
47 SLC25A46 91137
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which VPS13D is involved
No pathways found





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