Gene description for EFNB1
Gene name ephrin-B1
Gene symbol EFNB1
Other names/aliases CFND
CFNS
EFB1
EFL3
EPLG2
Elk-L
LERK2
Species Homo sapiens
 Database cross references - EFNB1
ExoCarta ExoCarta_1947
Vesiclepedia VP_1947
Entrez Gene 1947
HGNC 3226
MIM 300035
UniProt P98172  
 EFNB1 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Urine 19056867    
 Gene ontology annotations for EFNB1
Molecular Function
    protein binding GO:0005515 IPI
    ephrin receptor binding GO:0046875 IBA
    ephrin receptor binding GO:0046875 IDA
Biological Process
    neural crest cell migration GO:0001755 IEA
    cell adhesion GO:0007155 TAS
    cell-cell signaling GO:0007267 TAS
    axon guidance GO:0007411 IBA
    embryonic pattern specification GO:0009880 IEA
    T cell costimulation GO:0031295 IEA
    T cell proliferation GO:0042098 IEA
    positive regulation of T cell proliferation GO:0042102 IEA
    ephrin receptor signaling pathway GO:0048013 IBA
    regulation of autophagosome assembly GO:2000785 IDA
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    cell surface GO:0009986 IDA
    presynaptic membrane GO:0042734 IBA
    membrane raft GO:0045121 IEA
    synapse GO:0045202 ISS
    extracellular exosome GO:0070062 HDA
    glutamatergic synapse GO:0098978 IBA
 Experiment description of studies that identified EFNB1 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
6
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
7
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
9
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
19
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for EFNB1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF4G3 8672
Affinity Capture-MS Homo sapiens
2 INTS4  
Affinity Capture-MS Homo sapiens
3 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
4 AXL 558
Affinity Capture-MS Homo sapiens
5 DDR1 780
Affinity Capture-MS Homo sapiens
6 GJD3  
Proximity Label-MS Homo sapiens
7 FAM171A2 284069
Affinity Capture-MS Homo sapiens
8 FAM73A  
Affinity Capture-MS Homo sapiens
9 DEPDC1  
Affinity Capture-MS Homo sapiens
10 OCLN 100506658
Proximity Label-MS Homo sapiens
11 DNAAF5 54919
Affinity Capture-MS Homo sapiens
12 MARCKS 4082
Proximity Label-MS Homo sapiens
13 LAMP3  
Proximity Label-MS Homo sapiens
14 SLC39A4 55630
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 GJA1 2697
Proximity Label-MS Homo sapiens
16 TNPO1 3842
Affinity Capture-MS Homo sapiens
17 TSC2 7249
Affinity Capture-MS Homo sapiens
18 RAB9A 9367
Proximity Label-MS Homo sapiens
19 EIF2B2 8892
Affinity Capture-MS Homo sapiens
20 CAND2 23066
Affinity Capture-MS Homo sapiens
21 PCDH12 51294
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 NMNAT1  
Affinity Capture-MS Homo sapiens
23 SETX  
Affinity Capture-MS Homo sapiens
24 LAMP2 3920
Proximity Label-MS Homo sapiens
25 LRRC52  
Affinity Capture-MS Homo sapiens
26 HOOK2  
Affinity Capture-MS Homo sapiens
27 STX4 6810
Proximity Label-MS Homo sapiens
28 C1orf112  
Affinity Capture-MS Homo sapiens
29 PLEKHG4  
Affinity Capture-MS Homo sapiens
30 B3GAT1  
Proximity Label-MS Homo sapiens
31 HEATR3 55027
Affinity Capture-MS Homo sapiens
32 DAB2IP 153090
Affinity Capture-MS Homo sapiens
33 MLLT4 4301
Proximity Label-MS Homo sapiens
34 USO1 8615
Affinity Capture-MS Homo sapiens
35 CTLA4  
Affinity Capture-MS Homo sapiens
36 MON2 23041
Affinity Capture-MS Homo sapiens
37 EIF2B4 8890
Affinity Capture-MS Homo sapiens
38 TRDN 10345
Affinity Capture-MS Homo sapiens
39 ZDHHC11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 IQGAP1 8826
Affinity Capture-MS Homo sapiens
41 SRC 6714
Biochemical Activity Homo sapiens
42 CDH16  
Affinity Capture-MS Homo sapiens
43 RECQL4  
Affinity Capture-MS Homo sapiens
44 MAD2L2 10459
Affinity Capture-MS Homo sapiens
45 IPO8 10526
Affinity Capture-MS Homo sapiens
46 FANCD2  
Affinity Capture-MS Homo sapiens
47 FIBP 9158
Affinity Capture-MS Homo sapiens
48 ITFG3 83986
Affinity Capture-MS Homo sapiens
49 HYPM  
Affinity Capture-MS Homo sapiens
50 VCAM1 7412
Affinity Capture-MS Homo sapiens
51 DFNA5 1687
Affinity Capture-MS Homo sapiens
52 LYN 4067
Proximity Label-MS Homo sapiens
53 RAB35 11021
Proximity Label-MS Homo sapiens
54 SDCBP 6386
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
55 EXOC7 23265
Affinity Capture-MS Homo sapiens
56 PTPRF 5792
Affinity Capture-MS Homo sapiens
57 TMEM59 9528
Affinity Capture-MS Homo sapiens
58 EXOC5 10640
Affinity Capture-MS Homo sapiens
59 PLEKHH3  
Affinity Capture-MS Homo sapiens
60 KIAA1804  
Affinity Capture-MS Homo sapiens
61 LAMTOR1 55004
Proximity Label-MS Homo sapiens
62 AGBL5  
Affinity Capture-MS Homo sapiens
63 LMAN1 3998
Proximity Label-MS Homo sapiens
64 HEATR1 55127
Affinity Capture-MS Homo sapiens
65 XPO1 7514
Affinity Capture-MS Homo sapiens
66 ZIC2  
Affinity Capture-MS Homo sapiens
67 IPO11 51194
Affinity Capture-MS Homo sapiens
68 NRSN1  
Affinity Capture-MS Homo sapiens
69 NOP9 161424
Affinity Capture-MS Homo sapiens
70 NF1 4763
Affinity Capture-MS Homo sapiens
71 TBC1D9B 23061
Affinity Capture-MS Homo sapiens
72 SH3BP4 23677
Affinity Capture-MS Homo sapiens
73 TMEM213  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 CEACAM21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 CXADR 1525
Proximity Label-MS Homo sapiens
76 SHMT1 6470
Affinity Capture-MS Homo sapiens
77 KRBA1  
Affinity Capture-MS Homo sapiens
78 EIF2B5 8893
Affinity Capture-MS Homo sapiens
79 SMIM5  
Affinity Capture-MS Homo sapiens
80 MCAM 4162
Proximity Label-MS Homo sapiens
81 RAB4A 5867
Proximity Label-MS Homo sapiens
82 RNF213 57674
Affinity Capture-MS Homo sapiens
83 PDXDC1 23042
Affinity Capture-MS Homo sapiens
84 DNAJC5 80331
Proximity Label-MS Homo sapiens
85 RGS3 5998
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 ACAD10  
Affinity Capture-MS Homo sapiens
87 TNPO2 30000
Affinity Capture-MS Homo sapiens
88 DIRAS3  
Proximity Label-MS Homo sapiens
89 CKAP5 9793
Affinity Capture-MS Homo sapiens
90 LIN7C 55327
Affinity Capture-MS Homo sapiens
91 TTC12  
Affinity Capture-MS Homo sapiens
92 EXOC6 54536
Affinity Capture-MS Homo sapiens
93 IQCB1  
Affinity Capture-MS Homo sapiens
94 BRICD5  
Affinity Capture-MS Homo sapiens
95 YWHAQ 10971
Two-hybrid Homo sapiens
96 EXOC6B 23233
Affinity Capture-MS Homo sapiens
97 MTMR1 8776
Affinity Capture-MS Homo sapiens
98 DNM2 1785
Affinity Capture-MS Homo sapiens
99 MPP7 143098
Affinity Capture-MS Homo sapiens
100 RANBP6 26953
Affinity Capture-MS Homo sapiens
101 CCNY 219771
Affinity Capture-MS Homo sapiens
102 TIMELESS  
Affinity Capture-MS Homo sapiens
103 EPHB2 2048
Affinity Capture-MS Homo sapiens
104 STAG2 10735
Affinity Capture-MS Homo sapiens
105 USP32 84669
Affinity Capture-MS Homo sapiens
106 PHLPP1  
Affinity Capture-MS Homo sapiens
107 TTI1 9675
Affinity Capture-MS Homo sapiens
108 MINK1 50488
Affinity Capture-MS Homo sapiens
109 PICK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 TIGD5  
Affinity Capture-MS Homo sapiens
111 FAM160B1 57700
Affinity Capture-MS Homo sapiens
112 ACVR2A  
Affinity Capture-MS Homo sapiens
113 CXCR4 7852
Affinity Capture-MS Homo sapiens
114 TTYH1  
Affinity Capture-MS Homo sapiens
115 TFAP4 7023
Affinity Capture-MS Homo sapiens
116 SLC12A2 6558
Affinity Capture-MS Homo sapiens
117 SMEK2  
Affinity Capture-MS Homo sapiens
118 RAB5A 5868
Proximity Label-MS Homo sapiens
119 PANX1 24145
Proximity Label-MS Homo sapiens
120 TNFSF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 NCAPH2  
Affinity Capture-MS Homo sapiens
122 SLC39A5 283375
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 EPB41L4A 64097
Proximity Label-MS Homo sapiens
124 LAMP1 3916
Proximity Label-MS Homo sapiens
125 ARFGEF1 10565
Affinity Capture-MS Homo sapiens
126 PDGFRA 5156
Affinity Capture-MS Homo sapiens
127 SNX18 112574
Affinity Capture-MS Homo sapiens
128 CUL3 8452
Two-hybrid Homo sapiens
129 DIP2A 23181
Affinity Capture-MS Homo sapiens
130 CLEC4A  
Affinity Capture-MS Homo sapiens
131 TNPO3 23534
Affinity Capture-MS Homo sapiens
132 ARF6 382
Proximity Label-MS Homo sapiens
133 ATP1B3 483
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 KIAA1524 57650
Affinity Capture-MS Homo sapiens
135 EIF2B3 8891
Affinity Capture-MS Homo sapiens
136 SBF1 6305
Affinity Capture-MS Homo sapiens
137 GHITM 27069
Affinity Capture-MS Homo sapiens
138 TMEM169  
Affinity Capture-MS Homo sapiens
139 MSTO1 55154
Affinity Capture-MS Homo sapiens
140 XPO6 23214
Affinity Capture-MS Homo sapiens
141 RADIL  
Affinity Capture-MS Homo sapiens
142 SAAL1 113174
Affinity Capture-MS Homo sapiens
143 XPO4 64328
Affinity Capture-MS Homo sapiens
144 PI4K2B 55300
Affinity Capture-MS Homo sapiens
145 HLA-DQA1 3117
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 MYC  
Two-hybrid Homo sapiens
147 PTPN13 5783
Reconstituted Complex Homo sapiens
148 JAK1 3716
Affinity Capture-MS Homo sapiens
149 KIAA0391  
Affinity Capture-MS Homo sapiens
150 ACKR2  
Affinity Capture-MS Homo sapiens
151 PIK3R2 5296
Affinity Capture-MS Homo sapiens
152 ERBB2 2064
Affinity Capture-MS Homo sapiens
153 COMMD2 51122
Affinity Capture-MS Homo sapiens
154 CDHR5 53841
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 PVR 5817
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 RHOB 388
Proximity Label-MS Homo sapiens
157 EIF2B1 1967
Affinity Capture-MS Homo sapiens
158 TFIP11  
Affinity Capture-MS Homo sapiens
159 DYM  
Affinity Capture-MS Homo sapiens
160 THADA 63892
Affinity Capture-MS Homo sapiens
161 EFNB2 1948
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 FAM114A2  
Affinity Capture-MS Homo sapiens
163 EPHB3 2049
Affinity Capture-MS Homo sapiens
164 MAP7D2 256714
Affinity Capture-MS Homo sapiens
165 FLOT1 10211
Proximity Label-MS Homo sapiens
166 CCDC8  
Affinity Capture-MS Homo sapiens
167 NCAPG 64151
Affinity Capture-MS Homo sapiens
168 FAM120A 23196
Affinity Capture-MS Homo sapiens
169 SACS 26278
Affinity Capture-MS Homo sapiens
170 MAGEA8  
Affinity Capture-MS Homo sapiens
171 DENND6A 201627
Affinity Capture-MS Homo sapiens
172 TSPAN5 10098
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
174 KIF14 9928
Affinity Capture-MS Homo sapiens
175 WDFY2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 KNTC1 9735
Affinity Capture-MS Homo sapiens
177 NUP85 79902
Affinity Capture-MS Homo sapiens
178 TBC1D9  
Affinity Capture-MS Homo sapiens
179 EZR 7430
Proximity Label-MS Homo sapiens
180 PLCD3 113026
Affinity Capture-MS Homo sapiens
181 RYK 6259
Affinity Capture-MS Homo sapiens
182 TSPAN15 23555
Affinity Capture-MS Homo sapiens
183 SMURF1 57154
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
184 UBE4A 9354
Affinity Capture-MS Homo sapiens
185 VPS8 23355
Affinity Capture-MS Homo sapiens
186 ERGIC1 57222
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 C11orf52 91894
Proximity Label-MS Homo sapiens
188 NCK2 8440
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
189 GALNT12 79695
Affinity Capture-MS Homo sapiens
190 EPHA3 2042
Reconstituted Complex Homo sapiens
191 DDX11 1663
Affinity Capture-MS Homo sapiens
192 DGKZ  
Affinity Capture-MS Homo sapiens
193 RAB2A 5862
Proximity Label-MS Homo sapiens
194 AARS2  
Affinity Capture-MS Homo sapiens
195 HLA-DPA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 IPO4 79711
Affinity Capture-MS Homo sapiens
197 C16orf54 283897
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 RAB7A 7879
Proximity Label-MS Homo sapiens
199 DNM3 26052
Affinity Capture-MS Homo sapiens
200 RAB11A 8766
Proximity Label-MS Homo sapiens
201 IPO7 10527
Affinity Capture-MS Homo sapiens
202 CEP78 84131
Affinity Capture-MS Homo sapiens
203 EVA1B 55194
Affinity Capture-MS Homo sapiens
204 KRAS 3845
Proximity Label-MS Homo sapiens
205 RAB5C 5878
Proximity Label-MS Homo sapiens
206 SMURF2 64750
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
207 CAPN10  
Two-hybrid Homo sapiens
208 CAV1 857
Proximity Label-MS Homo sapiens
209 IPO9 55705
Affinity Capture-MS Homo sapiens
210 PKN3 29941
Affinity Capture-MS Homo sapiens
211 PLAC9 219348
Affinity Capture-MS Homo sapiens
212 RRP1 8568
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here