Gene description for ANKRD50
Gene name ankyrin repeat domain 50
Gene symbol ANKRD50
Other names/aliases -
Species Homo sapiens
 Database cross references - ANKRD50
ExoCarta ExoCarta_57182
Entrez Gene 57182
HGNC 29223
UniProt Q9ULJ7  
 ANKRD50 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for ANKRD50
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein transport GO:0015031 IEA
    retrograde transport, endosome to plasma membrane GO:1990126 IMP
Subcellular Localization
    endosome GO:0005768 IEA
 Experiment description of studies that identified ANKRD50 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for ANKRD50
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ANKRD50 is involved
No pathways found





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