Gene description for ARMCX3
Gene name armadillo repeat containing, X-linked 3
Gene symbol ARMCX3
Other names/aliases ALEX3
GASP6
dJ545K15.2
Species Homo sapiens
 Database cross references - ARMCX3
ExoCarta ExoCarta_51566
Entrez Gene 51566
HGNC 24065
MIM 300364
UniProt Q9UH62  
 ARMCX3 identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for ARMCX3
Biological Process
    cellular protein localization GO:0034613 IEA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IEA
Subcellular Localization
    integral component of mitochondrial outer membrane GO:0031307 IEA
 Experiment description of studies that identified ARMCX3 in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for ARMCX3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IMMT 10989
Two-hybrid Homo sapiens
2 CLTC 1213
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which ARMCX3 is involved
No pathways found





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