Gene description for KRAS
Gene name Kirsten rat sarcoma viral oncogene homolog
Gene symbol KRAS
Other names/aliases C-K-RAS
CFC2
K-RAS2A
K-RAS2B
K-RAS4A
K-RAS4B
KI-RAS
KRAS1
KRAS2
NS
NS3
RASK2
Species Homo sapiens
 Database cross references - KRAS
ExoCarta ExoCarta_3845
Vesiclepedia VP_3845
Entrez Gene 3845
HGNC 6407
MIM 190070
UniProt P01116  
 KRAS identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 19837982    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Prostate cancer cells 25844599    
Squamous carcinoma cells 20124223    
Thymus 23844026    
Urine 15326289    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for KRAS
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IMP
    GTPase activity GO:0003924 TAS
    G protein activity GO:0003925 IEA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IBA
    GDP binding GO:0019003 IBA
    identical protein binding GO:0042802 IPI
    protein-membrane adaptor activity GO:0043495 IEA
    protein-containing complex binding GO:0044877 IDA
Biological Process
    MAPK cascade GO:0000165 TAS
    positive regulation of protein phosphorylation GO:0001934 IMP
    Ras protein signal transduction GO:0007265 IBA
    visual learning GO:0008542 IEA
    gene expression GO:0010467 IEA
    positive regulation of gene expression GO:0010628 IMP
    glial cell proliferation GO:0014009 IEA
    Rac protein signal transduction GO:0016601 IEA
    forebrain astrocyte development GO:0021897 IEA
    actin cytoskeleton organization GO:0030036 IEA
    negative regulation of epithelial cell differentiation GO:0030857 IEA
    regulation of synaptic transmission, GABAergic GO:0032228 IEA
    positive regulation of Rac protein signal transduction GO:0035022 IEA
    skeletal muscle cell differentiation GO:0035914 IEA
    negative regulation of neuron apoptotic process GO:0043524 IEA
    regulation of long-term neuronal synaptic plasticity GO:0048169 IEA
    homeostasis of number of cells within a tissue GO:0048873 IEA
    striated muscle cell differentiation GO:0051146 IEA
    neuron apoptotic process GO:0051402 IEA
    positive regulation of glial cell proliferation GO:0060252 IEA
    epithelial tube branching involved in lung morphogenesis GO:0060441 IEA
    type I pneumocyte differentiation GO:0060509 IEA
Subcellular Localization
    Golgi membrane GO:0000139 TAS
    cytoplasm GO:0005737 IDA
    mitochondrial outer membrane GO:0005741 TAS
    endoplasmic reticulum membrane GO:0005789 TAS
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    focal adhesion GO:0005925 HDA
    cytoplasmic side of plasma membrane GO:0009898 IDA
    membrane GO:0016020 HDA
 Experiment description of studies that identified KRAS in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
8
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
12
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
13
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
27
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
28
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
33
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
36
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for KRAS
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CFAP20 29105
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
2 EIF3A 8661
Negative Genetic Homo sapiens
3 SEMA4D  
Proximity Label-MS Homo sapiens
4 AATF  
Negative Genetic Homo sapiens
5 ELP6 54859
Negative Genetic Homo sapiens
6 GUK1 2987
Negative Genetic Homo sapiens
7 DAG1 1605
Proximity Label-MS Homo sapiens
8 CAP1 10487
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
9 SLC2A1 6513
Proximity Label-MS Homo sapiens
10 SRGAP2 23380
Proximity Label-MS Homo sapiens
11 VHL  
Negative Genetic Homo sapiens
12 INTS1 26173
Negative Genetic Homo sapiens
13 EIF1 10209
Synthetic Lethality Homo sapiens
14 TAF1  
Synthetic Growth Defect Homo sapiens
Negative Genetic Homo sapiens
15 GFM2 84340
Negative Genetic Homo sapiens
16 WDR76  
Reconstituted Complex Homo sapiens
17 DARS 1615
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
18 USP6NL 9712
Proximity Label-MS Homo sapiens
19 ACTR3 10096
Negative Genetic Homo sapiens
20 PLCH1  
Proximity Label-MS Homo sapiens
21 ABCD3 5825
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
22 RPS9 6203
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
23 SCARB1 949
Proximity Label-MS Homo sapiens
24 MARCKSL1 65108
Proximity Label-MS Homo sapiens
25 SFN 2810
Affinity Capture-MS Homo sapiens
26 DPH3  
Negative Genetic Homo sapiens
27 NSFL1C 55968
Proximity Label-MS Homo sapiens
28 BTRC 8945
Affinity Capture-Western Homo sapiens
29 STARD7 56910
Negative Genetic Homo sapiens
30 TFRC 7037
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
31 KIF14 9928
Negative Genetic Homo sapiens
32 EMC1 23065
Negative Genetic Homo sapiens
33 CAMLG 819
Proximity Label-MS Homo sapiens
34 UNK  
Affinity Capture-RNA Homo sapiens
35 AURKA 6790
Negative Genetic Homo sapiens
36 AP3M1 26985
Proximity Label-MS Homo sapiens
37 WBP4  
Negative Genetic Homo sapiens
38 TCP1 6950
Negative Genetic Homo sapiens
39 NEUROG3  
Negative Genetic Homo sapiens
40 RRP9 9136
Negative Genetic Homo sapiens
41 LOC100507462  
Negative Genetic Homo sapiens
42 PLD1 5337
Proximity Label-MS Homo sapiens
43 SLC9A8 23315
Synthetic Growth Defect Homo sapiens
44 TUFM 7284
Negative Genetic Homo sapiens
45 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 YRDC 79693
Negative Genetic Homo sapiens
47 NOC4L 79050
Negative Genetic Homo sapiens
48 RBM17 84991
Negative Genetic Homo sapiens
49 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
50 EIF2B2 8892
Negative Genetic Homo sapiens
51 ENO1 2023
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
52 RFC4 5984
Negative Genetic Homo sapiens
53 ANAPC4 29945
Synthetic Lethality Homo sapiens
54 CUL2 8453
Negative Genetic Homo sapiens
55 MPP7 143098
Proximity Label-MS Homo sapiens
56 GTPBP4 23560
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
57 IQGAP2 10788
Proximity Label-MS Homo sapiens
58 RELL1 768211
Proximity Label-MS Homo sapiens
59 SDHC 6391
Negative Genetic Homo sapiens
60 HSPA5 3309
Negative Genetic Homo sapiens
61 NBPF9  
Negative Genetic Homo sapiens
62 RPS17 6218
Negative Genetic Homo sapiens
63 RBM39 9584
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
64 PNPLA4  
Synthetic Growth Defect Homo sapiens
65 NOC3L 64318
Negative Genetic Homo sapiens
66 DCAF7 10238
Negative Genetic Homo sapiens
67 AHCYL1 10768
Proximity Label-MS Homo sapiens
68 LMNB1 4001
Proximity Label-MS Homo sapiens
69 SCAMP1 9522
Proximity Label-MS Homo sapiens
70 LMO7 4008
Affinity Capture-MS Homo sapiens
71 TMEM199  
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
72 DIP2A 23181
Proximity Label-MS Homo sapiens
73 WDR55  
Negative Genetic Homo sapiens
74 EPRS 2058
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
75 EIF2S2 8894
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
76 NIP7 51388
Negative Genetic Homo sapiens
77 CDC42 998
Negative Genetic Homo sapiens
78 STRAP 11171
Negative Genetic Homo sapiens
79 MFHAS1 9258
Synthetic Growth Defect Homo sapiens
80 TJP2 9414
Proximity Label-MS Homo sapiens
81 TMEM237 65062
Proximity Label-MS Homo sapiens
82 LTV1  
Negative Genetic Homo sapiens
83 ZMYND8 23613
Affinity Capture-MS Homo sapiens
84 MRPL3  
Negative Genetic Homo sapiens
85 SORBS3 10174
Affinity Capture-MS Homo sapiens
86 NUBP1 4682
Negative Genetic Homo sapiens
87 SPATA5 166378
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
88 EFNB2 1948
Proximity Label-MS Homo sapiens
89 UPF2 26019
Negative Genetic Homo sapiens
90 CDC42EP4  
Proximity Label-MS Homo sapiens
91 ADH6 130
Two-hybrid Homo sapiens
92 SLC4A2 6522
Proximity Label-MS Homo sapiens
93 DDX46 9879
Negative Genetic Homo sapiens
94 CDAN1 146059
Negative Genetic Homo sapiens
95 NOSIP 51070
Negative Genetic Homo sapiens
96 YBX1 4904
Affinity Capture-MS Homo sapiens
97 GPRIN3  
Proximity Label-MS Homo sapiens
98 CADM1 23705
Proximity Label-MS Homo sapiens
99 POLR1B 84172
Negative Genetic Homo sapiens
100 RRS1 23212
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
101 THOC3  
Negative Genetic Homo sapiens
102 LARS2 23395
Negative Genetic Homo sapiens
103 PSMB7 5695
Negative Genetic Homo sapiens
104 PFDN1 5201
Negative Genetic Homo sapiens
105 DCTN2 10540
Synthetic Lethality Homo sapiens
106 ZNF764 92595
Synthetic Growth Defect Homo sapiens
107 KLK14  
Negative Genetic Homo sapiens
108 GTF2B 2959
Negative Genetic Homo sapiens
109 SSBP1 6742
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
110 PSMA1 5682
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
111 ERCC3  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
112 LARP7 51574
Synthetic Lethality Homo sapiens
113 PARS2 25973
Negative Genetic Homo sapiens
114 EIF4B 1975
Negative Genetic Homo sapiens
115 FAM50A 9130
Synthetic Lethality Homo sapiens
116 LMLN  
Synthetic Growth Defect Homo sapiens
117 RPL23A 6147
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
118 NUP85 79902
Negative Genetic Homo sapiens
119 GABPA 2551
Synthetic Lethality Homo sapiens
120 SKA2  
Negative Genetic Homo sapiens
121 EXOSC8  
Negative Genetic Homo sapiens
122 CTNND1 1500
Proximity Label-MS Homo sapiens
123 PSMD3 5709
Negative Genetic Homo sapiens
124 MORC2  
Synthetic Lethality Homo sapiens
125 PSMA6 5687
Negative Genetic Homo sapiens
126 F11R 50848
Proximity Label-MS Homo sapiens
127 ARMC5 79798
Negative Genetic Homo sapiens
128 GFPT1 2673
Negative Genetic Homo sapiens
129 RASL10A  
Synthetic Lethality Homo sapiens
130 TMEM41B 440026
Negative Genetic Homo sapiens
131 ARHGAP39  
Proximity Label-MS Homo sapiens
132 PAWR 5074
Affinity Capture-MS Homo sapiens
133 PRPF38A 84950
Negative Genetic Homo sapiens
134 NACA 4666
Negative Genetic Homo sapiens
135 URB1 9875
Negative Genetic Homo sapiens
136 PACSIN2 11252
Proximity Label-MS Homo sapiens
137 SHFM1 7979
Negative Genetic Homo sapiens
138 HRAS 3265
Reconstituted Complex Homo sapiens
139 URB2  
Synthetic Lethality Homo sapiens
140 CAND1 55832
Affinity Capture-MS Homo sapiens
141 MVK 4598
Negative Genetic Homo sapiens
142 SNRPF 6636
Synthetic Growth Defect Homo sapiens
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
143 AFTPH  
Synthetic Lethality Homo sapiens
144 RPS3 6188
Synthetic Lethality Homo sapiens
145 USB1  
Negative Genetic Homo sapiens
146 RPS18 6222
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
147 METAP2 10988
Negative Genetic Homo sapiens
148 IGHMBP2 3508
Affinity Capture-MS Homo sapiens
149 LRRC1 55227
Proximity Label-MS Homo sapiens
150 DDX24 57062
Affinity Capture-MS Homo sapiens
151 COPS6 10980
Negative Genetic Homo sapiens
152 CPSF4  
Negative Genetic Homo sapiens
153 HARS2 23438
Negative Genetic Homo sapiens
154 FAM83D 81610
Affinity Capture-MS Homo sapiens
155 NFS1 9054
Negative Genetic Homo sapiens
156 MAP4K5 11183
Proximity Label-MS Homo sapiens
157 NUP93 9688
Negative Genetic Homo sapiens
158 TVP23A  
Synthetic Lethality Homo sapiens
159 WASH1 100287171
Negative Genetic Homo sapiens
160 ITFG3 83986
Proximity Label-MS Homo sapiens
161 TOMM40 10452
Negative Genetic Homo sapiens
162 FGD6  
Proximity Label-MS Homo sapiens
163 FTSJ1 24140
Proximity Label-MS Homo sapiens
164 PES1 23481
Negative Genetic Homo sapiens
165 ZCRB1  
Negative Genetic Homo sapiens
166 YWHAB 7529
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 ARPC1B 10095
Affinity Capture-MS Homo sapiens
168 SDK2 54549
Proximity Label-MS Homo sapiens
169 JMJD6 23210
Negative Genetic Homo sapiens
170 IPO11 51194
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
171 SYMPK 8189
Negative Genetic Homo sapiens
172 TTC4  
Negative Genetic Homo sapiens
173 DDX21 9188
Negative Genetic Homo sapiens
174 RTFDC1  
Negative Genetic Homo sapiens
175 MOB4 25843
Negative Genetic Homo sapiens
176 FAM92B  
Synthetic Lethality Homo sapiens
177 CD99 4267
Proximity Label-MS Homo sapiens
178 LYN 4067
Proximity Label-MS Homo sapiens
179 NBN 4683
Synthetic Lethality Homo sapiens
180 HSPE1-MOB4  
Negative Genetic Homo sapiens
181 NCAPD3 23310
Negative Genetic Homo sapiens
182 HAUS8  
Negative Genetic Homo sapiens
183 NKRF 55922
Affinity Capture-MS Homo sapiens
184 INTS7  
Negative Genetic Homo sapiens
185 CLEC11A 6320
Synthetic Lethality Homo sapiens
186 PREB 10113
Negative Genetic Homo sapiens
187 NOL4  
Synthetic Lethality Homo sapiens
188 PHACTR2  
Proximity Label-MS Homo sapiens
189 RPLP0 6175
Negative Genetic Homo sapiens
190 ACTR10 55860
Negative Genetic Homo sapiens
191 TIMELESS  
Negative Genetic Homo sapiens
192 ATP6V1E1 529
Negative Genetic Homo sapiens
193 CARS 833
Negative Genetic Homo sapiens
194 SEPT6 23157
Proximity Label-MS Homo sapiens
195 CDIPT 10423
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
196 TPX2  
Negative Genetic Homo sapiens
197 STON2 85439
Proximity Label-MS Homo sapiens
198 PPAN-P2RY11  
Synthetic Lethality Homo sapiens
199 MARVELD2 153562
Proximity Label-MS Homo sapiens
200 DIP2B 57609
Proximity Label-MS Homo sapiens
201 XPO1 7514
Negative Genetic Homo sapiens
202 EIF6 3692
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
203 ADCY9 115
Proximity Label-MS Homo sapiens
204 WBSCR22  
Negative Genetic Homo sapiens
205 RGP1 9827
Negative Genetic Homo sapiens
206 UBE2L6 9246
Synthetic Lethality Homo sapiens
207 SLC26A2 1836
Proximity Label-MS Homo sapiens
208 SPECC1 92521
Proximity Label-MS Homo sapiens
209 SNF8 11267
Negative Genetic Homo sapiens
210 UBL5 59286
Negative Genetic Homo sapiens
211 LARS 51520
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
212 ZNF492  
Negative Genetic Homo sapiens
213 TCEB1 6921
Negative Genetic Homo sapiens
214 YWHAQ 10971
Affinity Capture-MS Homo sapiens
215 RPS27 6232
Negative Genetic Homo sapiens
216 GPN2  
Negative Genetic Homo sapiens
217 FAM91A1 157769
Proximity Label-MS Homo sapiens
218 SLC3A2 6520
Proximity Label-MS Homo sapiens
219 TRAPPC4 51399
Negative Genetic Homo sapiens
Affinity Capture-MS Homo sapiens
220 CABLES1  
Proximity Label-MS Homo sapiens
221 NPIPB6  
Negative Genetic Homo sapiens
222 DDB1 1642
Negative Genetic Homo sapiens
223 DDRGK1 65992
Proximity Label-MS Homo sapiens
224 WDR44 54521
Proximity Label-MS Homo sapiens
225 PGAM1 5223
Negative Genetic Homo sapiens
226 ARGLU1  
Negative Genetic Homo sapiens
227 KIAA0040  
Proximity Label-MS Homo sapiens
228 NOG 9241
Synthetic Lethality Homo sapiens
229 CPNE8 144402
Proximity Label-MS Homo sapiens
230 HUWE1 10075
Negative Genetic Homo sapiens
231 PHGDH 26227
Affinity Capture-MS Homo sapiens
232 SLC16A1 6566
Proximity Label-MS Homo sapiens
233 TAF6 6878
Negative Genetic Homo sapiens
234 ATP6V0B 533
Negative Genetic Homo sapiens
235 PLXNB2 23654
Proximity Label-MS Homo sapiens
236 TERF2  
Negative Genetic Homo sapiens
237 SLC35B1 10237
Negative Genetic Homo sapiens
238 TRAPPC5 126003
Negative Genetic Homo sapiens
239 PLEKHA5 54477
Proximity Label-MS Homo sapiens
240 H3F3A 3020
Negative Genetic Homo sapiens
241 MAX  
Negative Genetic Homo sapiens
242 FAM72C  
Negative Genetic Homo sapiens
243 RPP25L  
Synthetic Lethality Homo sapiens
244 SF3B4 10262
Negative Genetic Homo sapiens
245 XPR1 9213
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
246 RPS4X 6191
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
247 SQSTM1 8878
Affinity Capture-MS Homo sapiens
248 SOS1 6654
Synthetic Lethality Homo sapiens
249 UTP23  
Negative Genetic Homo sapiens
250 PARPBP  
Synthetic Lethality Homo sapiens
251 CAPRIN1 4076
Negative Genetic Homo sapiens
252 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
253 BUB3 9184
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
254 CDK1 983
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
255 RAD50 10111
Negative Genetic Homo sapiens
256 RPS26 6231
Negative Genetic Homo sapiens
257 AHCYL2 23382
Proximity Label-MS Homo sapiens
258 OSBPL3 26031
Proximity Label-MS Homo sapiens
259 RIOK2 55781
Negative Genetic Homo sapiens
260 DHX38 9785
Negative Genetic Homo sapiens
261 KIAA0754  
Proximity Label-MS Homo sapiens
262 C16orf72 29035
Synthetic Growth Defect Homo sapiens
263 ATP1A1 476
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
264 YKT6 10652
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
265 IGF2R 3482
Proximity Label-MS Homo sapiens
266 C12orf45  
Negative Genetic Homo sapiens
267 ST13 6767
Synthetic Lethality Homo sapiens
268 QRSL1  
Negative Genetic Homo sapiens
269 CKAP4 10970
Proximity Label-MS Homo sapiens
270 NGB  
Synthetic Lethality Homo sapiens
271 PRMT1 3276
Negative Genetic Homo sapiens
272 DBR1  
Negative Genetic Homo sapiens
273 PRKRIR  
Negative Genetic Homo sapiens
274 TRAIP  
Negative Genetic Homo sapiens
275 AP2S1 1175
Negative Genetic Homo sapiens
276 CGB1  
Negative Genetic Homo sapiens
277 PPIAL4G  
Negative Genetic Homo sapiens
278 SHOC2 8036
Two-hybrid Homo sapiens
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
279 PTMA 5757
Synthetic Lethality Homo sapiens
280 TPD52L2 7165
Proximity Label-MS Homo sapiens
281 PFKP 5214
Synthetic Lethality Homo sapiens
282 MDFI  
Two-hybrid Homo sapiens
283 BUB1B  
Negative Genetic Homo sapiens
284 UQCRB 7381
Negative Genetic Homo sapiens
285 SSB 6741
Negative Genetic Homo sapiens
286 HNRNPR 10236
Affinity Capture-MS Homo sapiens
287 PTPN1 5770
Proximity Label-MS Homo sapiens
288 APBB1  
Proximity Label-MS Homo sapiens
289 LTN1 26046
Synthetic Lethality Homo sapiens
290 CGB5  
Negative Genetic Homo sapiens
291 PI4KA 5297
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
292 INTS8  
Negative Genetic Homo sapiens
293 DIMT1 27292
Negative Genetic Homo sapiens
294 RPAIN  
Negative Genetic Homo sapiens
295 RPL10A 4736
Negative Genetic Homo sapiens
296 PSMG3 84262
Negative Genetic Homo sapiens
297 ERICH5  
Proximity Label-MS Homo sapiens
298 PCNT  
Synthetic Lethality Homo sapiens
299 TAOK3 51347
Proximity Label-MS Homo sapiens
300 SDHB 6390
Negative Genetic Homo sapiens
301 IMP3 55272
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
302 CDK12 51755
Negative Genetic Homo sapiens
303 YARS2  
Negative Genetic Homo sapiens
304 CCT3 7203
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
305 NPM1 4869
Negative Genetic Homo sapiens
306 PNPLA6 10908
Negative Genetic Homo sapiens
307 SRP14 6727
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
308 RASSF5 83593
Reconstituted Complex Homo sapiens
309 LIPT2  
Negative Genetic Homo sapiens
310 CCDC47 57003
Proximity Label-MS Homo sapiens
311 ALCAM 214
Proximity Label-MS Homo sapiens
312 RPS3A 6189
Negative Genetic Homo sapiens
313 GTF3A 2971
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
314 MRPL4 51073
Negative Genetic Homo sapiens
315 GPRC5C 55890
Proximity Label-MS Homo sapiens
316 MCAM 4162
Proximity Label-MS Homo sapiens
317 RBM8A 9939
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
318 HSPA8 3312
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
319 SLC30A1 7779
Proximity Label-MS Homo sapiens
320 ALAS1  
Negative Genetic Homo sapiens
321 BANP  
Negative Genetic Homo sapiens
322 SLC1A3 6507
Proximity Label-MS Homo sapiens
323 MYO18A 399687
Proximity Label-MS Homo sapiens
324 SCAF1  
Negative Genetic Homo sapiens
325 OR4F21  
Negative Genetic Homo sapiens
326 ZCCHC9  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
327 RPL9 6133
Negative Genetic Homo sapiens
328 ITGA6 3655
Proximity Label-MS Homo sapiens
329 CTU2 348180
Negative Genetic Homo sapiens
330 SPDL1  
Negative Genetic Homo sapiens
331 DCTN5 84516
Negative Genetic Homo sapiens
332 CXADR 1525
Proximity Label-MS Homo sapiens
333 CHCHD3 54927
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
334 GOLGA8K  
Negative Genetic Homo sapiens
335 ACACA 31
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
336 TUBA1B 10376
Negative Genetic Homo sapiens
337 GTF2H1 2965
Negative Genetic Homo sapiens
338 BARD1 580
Synthetic Lethality Homo sapiens
339 ARNT 405
Affinity Capture-MS Homo sapiens
340 KIF11 3832
Negative Genetic Homo sapiens
341 SLC6A6 6533
Proximity Label-MS Homo sapiens
342 KPNB1 3837
Negative Genetic Homo sapiens
343 ENY2 56943
Synthetic Lethality Homo sapiens
344 TECR 9524
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
345 PELP1 27043
Negative Genetic Homo sapiens
346 NKTR  
Negative Genetic Homo sapiens
347 AGAP5  
Negative Genetic Homo sapiens
348 DNM1L 10059
Synthetic Lethality Homo sapiens
349 SF3A3 10946
Negative Genetic Homo sapiens
350 TXNDC11 51061
Synthetic Lethality Homo sapiens
351 RFK 55312
Negative Genetic Homo sapiens
352 KIF18A  
Negative Genetic Homo sapiens
353 PCBP2 5094
Negative Genetic Homo sapiens
354 RBBP6 5930
Synthetic Lethality Homo sapiens
355 SF3B2 10992
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
356 LSM8 51691
Negative Genetic Homo sapiens
357 YAE1D1  
Negative Genetic Homo sapiens
358 PREX1  
Synthetic Lethality Homo sapiens
359 POLR3A 11128
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
360 MYH8 4626
Synthetic Lethality Homo sapiens
361 MRPL37 51253
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
362 TENM3 55714
Proximity Label-MS Homo sapiens
363 ICMT  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
364 PSMA2 5683
Negative Genetic Homo sapiens
365 KARS 3735
Negative Genetic Homo sapiens
366 ZC3H8  
Negative Genetic Homo sapiens
367 ATXN10 25814
Negative Genetic Homo sapiens
368 COX6B1 1340
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
369 EIF2B3 8891
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
370 LPAR1 1902
Two-hybrid Homo sapiens
371 BAIAP2L1 55971
Proximity Label-MS Homo sapiens
372 KIAA0430  
Affinity Capture-MS Homo sapiens
373 GNA11 2767
Proximity Label-MS Homo sapiens
374 MYO1D 4642
Proximity Label-MS Homo sapiens
375 PRPF19 27339
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
376 RPS13 6207
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
377 EXOSC3 51010
Negative Genetic Homo sapiens
378 C14orf80  
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
379 RPL12 6136
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
380 SKIV2L2 23517
Negative Genetic Homo sapiens
381 RAF1 5894
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
Two-hybrid Homo sapiens
Synthetic Lethality Homo sapiens
Synthetic Lethality Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
382 NOB1  
Negative Genetic Homo sapiens
383 RANBP1 5902
Synthetic Lethality Homo sapiens
384 MRPL38  
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
385 ARHGAP31 57514
Proximity Label-MS Homo sapiens
386 NEDD4L 23327
Synthetic Lethality Homo sapiens
387 NAA10 8260
Negative Genetic Homo sapiens
388 SNRPD2 6633
Synthetic Growth Defect Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
389 ADAM10 102
Synthetic Growth Defect Homo sapiens
390 MECR 51102
Synthetic Lethality Homo sapiens
391 PIP5K1A 8394
Proximity Label-MS Homo sapiens
392 RPL37 6167
Negative Genetic Homo sapiens
393 SPCS3 60559
Negative Genetic Homo sapiens
394 PVRL2 5819
Proximity Label-MS Homo sapiens
395 MAPKAP1 79109
Proximity Label-MS Homo sapiens
396 EPB41L4B 54566
Proximity Label-MS Homo sapiens
397 AP4S1 11154
Synthetic Lethality Homo sapiens
398 VPS28 51160
Negative Genetic Homo sapiens
399 MTBP  
Negative Genetic Homo sapiens
400 ULBP1  
Synthetic Lethality Homo sapiens
401 MCM5 4174
Negative Genetic Homo sapiens
402 TCEA1 6917
Synthetic Lethality Homo sapiens
403 ELL  
Negative Genetic Homo sapiens
404 RPTOR 57521
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
405 FLOT2 2319
Proximity Label-MS Homo sapiens
406 NMBR  
Synthetic Lethality Homo sapiens
407 PDCL 5082
Negative Genetic Homo sapiens
408 RNPC3  
Negative Genetic Homo sapiens
409 TGIF1  
Negative Genetic Homo sapiens
410 UFL1 23376
Synthetic Lethality Homo sapiens
411 NF1 4763
Proximity Label-MS Homo sapiens
412 NEDD1 121441
Synthetic Lethality Homo sapiens
413 SLC1A4 6509
Proximity Label-MS Homo sapiens
414 PHF3  
Synthetic Lethality Homo sapiens
415 RPRD1B 58490
Negative Genetic Homo sapiens
416 CD44 960
Proximity Label-MS Homo sapiens
417 COPS4 51138
Negative Genetic Homo sapiens
418 TFAM 7019
Negative Genetic Homo sapiens
419 NOL9 79707
Negative Genetic Homo sapiens
420 LUC7L3 51747
Negative Genetic Homo sapiens
421 HLA-C 3107
Proximity Label-MS Homo sapiens
422 EIF3L 51386
Negative Genetic Homo sapiens
423 GNL2 29889
Negative Genetic Homo sapiens
424 HKDC1 80201
Synthetic Growth Defect Homo sapiens
425 RPS12 6206
Negative Genetic Homo sapiens
426 ACTR2 10097
Negative Genetic Homo sapiens
Affinity Capture-MS Homo sapiens
427 SLC39A10 57181
Proximity Label-MS Homo sapiens
428 AMY1B 277
Negative Genetic Homo sapiens
429 RFTN1 23180
Proximity Label-MS Homo sapiens
430 CDC42BPB 9578
Proximity Label-MS Homo sapiens
431 PAPPA2 60676
Synthetic Lethality Homo sapiens
432 SMG6  
Synthetic Lethality Homo sapiens
433 LPHN1  
Proximity Label-MS Homo sapiens
434 PAICS 10606
Negative Genetic Homo sapiens
435 NUPL1 9818
Negative Genetic Homo sapiens
436 STIM2 57620
Proximity Label-MS Homo sapiens
437 CCT4 10575
Negative Genetic Homo sapiens
438 BASP1 10409
Proximity Label-MS Homo sapiens
439 PLEKHA2 59339
Affinity Capture-MS Homo sapiens
440 CFL1 1072
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
441 PRR5  
Proximity Label-MS Homo sapiens
442 TOMM22 56993
Negative Genetic Homo sapiens
443 FAM126A 84668
Proximity Label-MS Homo sapiens
444 YES1 7525
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
445 RNH1 6050
Negative Genetic Homo sapiens
446 EXOC3L2  
Negative Genetic Homo sapiens
447 RPS20 6224
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
448 PPP1R12A 4659
Negative Genetic Homo sapiens
449 GTF3C3 9330
Negative Genetic Homo sapiens
450 SEMA6A  
Proximity Label-MS Homo sapiens
451 DGKH 160851
Proximity Label-MS Homo sapiens
452 PCID2 55795
Negative Genetic Homo sapiens
453 NAA11 84779
Synthetic Lethality Homo sapiens
454 POLR2I 5438
Negative Genetic Homo sapiens
455 DIAPH3 81624
Proximity Label-MS Homo sapiens
456 SNRPC 6631
Negative Genetic Homo sapiens
457 UNC5C  
Proximity Label-MS Homo sapiens
458 TSEN15 116461
Negative Genetic Homo sapiens
459 TEAD1  
Negative Genetic Homo sapiens
460 RAD51  
Negative Genetic Homo sapiens
461 PGRMC2 10424
Proximity Label-MS Homo sapiens
462 ABHD5 51099
Synthetic Lethality Homo sapiens
463 PDE11A  
Negative Genetic Homo sapiens
464 INO80E  
Synthetic Lethality Homo sapiens
465 SOWAHC  
Proximity Label-MS Homo sapiens
466 SRP68 6730
Affinity Capture-MS Homo sapiens
467 VPS53 55275
Negative Genetic Homo sapiens
468 ATP5H 10476
Negative Genetic Homo sapiens
469 PPP1R15B  
Negative Genetic Homo sapiens
470 TMEM2 23670
Proximity Label-MS Homo sapiens
471 SPNS2 124976
Synthetic Lethality Homo sapiens
472 C2orf15  
Negative Genetic Homo sapiens
473 WDR1 9948
Negative Genetic Homo sapiens
474 WRN 7486
Synthetic Lethality Homo sapiens
475 TBCE 6905
Negative Genetic Homo sapiens
476 MRC2 9902
Synthetic Lethality Homo sapiens
477 HMGA1 3159
Negative Genetic Homo sapiens
478 VEZT 55591
Proximity Label-MS Homo sapiens
479 POLD1 5424
Negative Genetic Homo sapiens
480 DUT 1854
Negative Genetic Homo sapiens
481 AGAP11  
Negative Genetic Homo sapiens
482 CCT5 22948
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
483 GALE 2582
Negative Genetic Homo sapiens
484 ZNF85  
Synthetic Lethality Homo sapiens
485 HSCB 150274
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
486 ALG1L2  
Negative Genetic Homo sapiens
487 RPS10-NUDT3 100529239
Negative Genetic Homo sapiens
488 LOC100144595  
Negative Genetic Homo sapiens
489 DDX5 1655
Negative Genetic Homo sapiens
490 SERPINH1 871
Proximity Label-MS Homo sapiens
491 ANAPC10  
Synthetic Growth Defect Homo sapiens
Synthetic Lethality Homo sapiens
492 IMP4  
Synthetic Lethality Homo sapiens
493 MMS19 64210
Negative Genetic Homo sapiens
494 DDX1 1653
Synthetic Lethality Homo sapiens
495 LYRM4 57128
Negative Genetic Homo sapiens
496 BRAF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
497 ATP2B4 493
Proximity Label-MS Homo sapiens
498 ITCH 83737
Proximity Label-MS Homo sapiens
499 PRPF31 26121
Synthetic Growth Defect Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
500 GLTSCR2  
Negative Genetic Homo sapiens
501 SLC7A1 6541
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
502 COX4I1 1327
Negative Genetic Homo sapiens
503 LRRC8A 56262
Proximity Label-MS Homo sapiens
504 GOLGA6L1  
Negative Genetic Homo sapiens
505 DPH2 1802
Negative Genetic Homo sapiens
506 WDR82 80335
Negative Genetic Homo sapiens
507 STK10 6793
Proximity Label-MS Homo sapiens
508 MBTPS1 8720
Negative Genetic Homo sapiens
509 DDX59 83479
Negative Genetic Homo sapiens
510 CACHD1  
Proximity Label-MS Homo sapiens
511 GINS2  
Negative Genetic Homo sapiens
512 SFPQ 6421
Synthetic Growth Defect Homo sapiens
Negative Genetic Homo sapiens
513 BMS1  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
514 IPO5 3843
Affinity Capture-MS Homo sapiens
515 PSEN1 5663
Proximity Label-MS Homo sapiens
516 CLINT1 9685
Proximity Label-MS Homo sapiens
517 PITPNM3 83394
Synthetic Lethality Homo sapiens
518 POLR2H 5437
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
519 PANX1 24145
Proximity Label-MS Homo sapiens
520 EIF4G1 1981
Negative Genetic Homo sapiens
521 DOCK7 85440
Proximity Label-MS Homo sapiens
522 PNN 5411
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
523 LETM1 3954
Negative Genetic Homo sapiens
524 NCKAP1 10787
Proximity Label-MS Homo sapiens
525 MAT1A 4143
Synthetic Lethality Homo sapiens
526 NAT10 55226
Negative Genetic Homo sapiens
527 RFC2 5982
Negative Genetic Homo sapiens
528 HCFC1 3054
Negative Genetic Homo sapiens
529 MIPEP  
Negative Genetic Homo sapiens
530 ZBTB12  
Synthetic Lethality Homo sapiens
531 SLC22A5 6584
Proximity Label-MS Homo sapiens
532 TRIO 7204
Proximity Label-MS Homo sapiens
533 XAB2 56949
Negative Genetic Homo sapiens
534 TXN 7295
Negative Genetic Homo sapiens
535 ELAC2 60528
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
536 PPIAL4C 653598
Negative Genetic Homo sapiens
537 SMU1 55234
Negative Genetic Homo sapiens
538 TBCD 6904
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
539 NXF1 10482
Negative Genetic Homo sapiens
540 EPHA7 2045
Proximity Label-MS Homo sapiens
541 ISY1-RAB43 100534599
Negative Genetic Homo sapiens
542 DIS3 22894
Negative Genetic Homo sapiens
543 EPN1 29924
Proximity Label-MS Homo sapiens
544 FRAT1 10023
Affinity Capture-MS Homo sapiens
545 MMS22L  
Negative Genetic Homo sapiens
546 VARS2  
Negative Genetic Homo sapiens
547 PSMB5 5693
Negative Genetic Homo sapiens
548 MAK16  
Negative Genetic Homo sapiens
549 DHX37  
Negative Genetic Homo sapiens
550 ATP5C1 509
Synthetic Lethality Homo sapiens
551 PPFIA1 8500
Proximity Label-MS Homo sapiens
552 NOL6 65083
Negative Genetic Homo sapiens
553 DDX49 54555
Negative Genetic Homo sapiens
554 HAUS4  
Negative Genetic Homo sapiens
555 DCTN4 51164
Negative Genetic Homo sapiens
556 RALBP1 10928
Proximity Label-MS Homo sapiens
557 ARL2 402
Negative Genetic Homo sapiens
558 PPP4C 5531
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
559 MVD 4597
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
560 NUP133 55746
Negative Genetic Homo sapiens
561 CPSF6 11052
Negative Genetic Homo sapiens
562 EHD4 30844
Proximity Label-MS Homo sapiens
563 SSU72 29101
Negative Genetic Homo sapiens
564 MRPL43 84545
Negative Genetic Homo sapiens
565 MED8  
Negative Genetic Homo sapiens
566 PET100  
Negative Genetic Homo sapiens
567 EPB41L2 2037
Proximity Label-MS Homo sapiens
568 ANAPC2 29882
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
569 ZDHHC8 29801
Proximity Label-MS Homo sapiens
570 DHX16 8449
Negative Genetic Homo sapiens
571 GTF2H3  
Negative Genetic Homo sapiens
572 EYA4 2070
Affinity Capture-Western Homo sapiens
573 C12orf66  
Synthetic Growth Defect Homo sapiens
574 CELSR2  
Proximity Label-MS Homo sapiens
575 CAD 790
Negative Genetic Homo sapiens
576 MRPS9 64965
Negative Genetic Homo sapiens
577 RPL23 9349
Negative Genetic Homo sapiens
578 MTG1  
Negative Genetic Homo sapiens
579 IPO13 9670
Negative Genetic Homo sapiens
580 OXCT2  
Negative Genetic Homo sapiens
581 HNRNPU 3192
Negative Genetic Homo sapiens
582 GNB2L1 10399
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
583 CHAF1B  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
584 ESYT1 23344
Proximity Label-MS Homo sapiens
585 ARHGAP12  
Proximity Label-MS Homo sapiens
586 NEDD8 4738
Negative Genetic Homo sapiens
587 MED22  
Negative Genetic Homo sapiens
588 ARHGAP1 392
Proximity Label-MS Homo sapiens
589 WDR6 11180
Proximity Label-MS Homo sapiens
590 UTRN 7402
Proximity Label-MS Homo sapiens
591 PPP1CB 5500
Negative Genetic Homo sapiens
592 NPRL2  
Affinity Capture-MS Homo sapiens
593 PTPRG 5793
Proximity Label-MS Homo sapiens
594 LLGL1 3996
Proximity Label-MS Homo sapiens
595 ARPC2 10109
Negative Genetic Homo sapiens
596 UTP11L  
Negative Genetic Homo sapiens
597 DYNC1I2 1781
Negative Genetic Homo sapiens
598 RCL1 10171
Negative Genetic Homo sapiens
599 ARPC4 10093
Negative Genetic Homo sapiens
600 JPH1 56704
Proximity Label-MS Homo sapiens
601 UBA1 7317
Negative Genetic Homo sapiens
602 CMPK1 51727
Negative Genetic Homo sapiens
603 RBM12 10137
Negative Genetic Homo sapiens
604 PRPF40A 55660
Negative Genetic Homo sapiens
605 PPAT 5471
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
606 SEPT9 10801
Proximity Label-MS Homo sapiens
607 CPSF2 53981
Negative Genetic Homo sapiens
608 DHX33  
Negative Genetic Homo sapiens
609 CRNKL1 51340
Negative Genetic Homo sapiens
610 USP17L29  
Negative Genetic Homo sapiens
611 GMNN  
Negative Genetic Homo sapiens
612 CHAF1A  
Negative Genetic Homo sapiens
613 DHDDS  
Negative Genetic Homo sapiens
614 FXN  
Negative Genetic Homo sapiens
615 EIF3E 3646
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
616 SYS1  
Negative Genetic Homo sapiens
617 RAB1A 5861
Proximity Label-MS Homo sapiens
618 AMD1  
Negative Genetic Homo sapiens
619 ATP5D 513
Negative Genetic Homo sapiens
620 FBXO5  
Synthetic Lethality Homo sapiens
621 BRF2  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
622 PFDN6 10471
Negative Genetic Homo sapiens
623 SLC12A7 10723
Proximity Label-MS Homo sapiens
624 RPS11 6205
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
625 TNKS1BP1 85456
Proximity Label-MS Homo sapiens
626 RPL19 6143
Negative Genetic Homo sapiens
627 MYL6 4637
Affinity Capture-MS Homo sapiens
628 ATP11A 23250
Proximity Label-MS Homo sapiens
629 MVB12B 89853
Synthetic Lethality Homo sapiens
630 GOLIM4 27333
Affinity Capture-MS Homo sapiens
631 SRBD1  
Negative Genetic Homo sapiens
632 TBC1D3F  
Negative Genetic Homo sapiens
633 TXNL4B  
Negative Genetic Homo sapiens
634 USP17L19  
Synthetic Lethality Homo sapiens
635 ERCC2 2068
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
636 MEPCE 56257
Negative Genetic Homo sapiens
637 CENPL  
Negative Genetic Homo sapiens
638 UBE2I 7329
Negative Genetic Homo sapiens
639 EFR3B  
Proximity Label-MS Homo sapiens
640 COPB1 1315
Negative Genetic Homo sapiens
641 RAD9A  
Negative Genetic Homo sapiens
642 RPL18A 6142
Synthetic Growth Defect Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
643 CIRH1A 84916
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
644 CDH1 999
Affinity Capture-MS Homo sapiens
645 UBA3 9039
Negative Genetic Homo sapiens
646 TANC1 85461
Proximity Label-MS Homo sapiens
647 CKAP5 9793
Negative Genetic Homo sapiens
648 TGS1  
Negative Genetic Homo sapiens
649 XPOT 11260
Synthetic Lethality Homo sapiens
650 CYC1 1537
Synthetic Lethality Homo sapiens
651 THG1L 54974
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
652 ZNF581  
Negative Genetic Homo sapiens
653 ZRSR2  
Negative Genetic Homo sapiens
654 VPS18 57617
Negative Genetic Homo sapiens
655 SRPK1 6732
Affinity Capture-MS Homo sapiens
656 EPHB4 2050
Proximity Label-MS Homo sapiens
657 PPP1R8 5511
Negative Genetic Homo sapiens
658 IGBP1 3476
Negative Genetic Homo sapiens
659 ZDHHC20 253832
Proximity Label-MS Homo sapiens
660 DST 667
Proximity Label-MS Homo sapiens
661 ISCA1  
Negative Genetic Homo sapiens
662 RNF40 9810
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
663 ANO6 196527
Proximity Label-MS Homo sapiens
664 RARS2  
Negative Genetic Homo sapiens
665 EARS2  
Negative Genetic Homo sapiens
666 FAM129B 64855
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
667 GMPPB 29925
Negative Genetic Homo sapiens
668 PAFAH1B1 5048
Negative Genetic Homo sapiens
669 MRPS12  
Negative Genetic Homo sapiens
670 MRTO4 51154
Negative Genetic Homo sapiens
671 NUBP2 10101
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
672 AGAP9  
Negative Genetic Homo sapiens
673 NSMCE2  
Negative Genetic Homo sapiens
674 MAGEB1  
Synthetic Lethality Homo sapiens
675 RQCD1 9125
Synthetic Lethality Homo sapiens
676 CUL3 8452
Negative Genetic Homo sapiens
677 MTNR1A  
Synthetic Growth Defect Homo sapiens
678 PAPD5 64282
Negative Genetic Homo sapiens
679 RAD51C  
Negative Genetic Homo sapiens
680 RPL35 11224
Negative Genetic Homo sapiens
681 TP53TG3C  
Negative Genetic Homo sapiens
682 SPDYE2B  
Negative Genetic Homo sapiens
683 INCENP 3619
Negative Genetic Homo sapiens
684 RPGR  
Proximity Label-MS Homo sapiens
685 UBA2 10054
Negative Genetic Homo sapiens
686 MFAP1  
Negative Genetic Homo sapiens
687 WRB 7485
Negative Genetic Homo sapiens
688 COX6C 1345
Synthetic Lethality Homo sapiens
689 IGSF3 3321
Proximity Label-MS Homo sapiens
690 OSBP 5007
Negative Genetic Homo sapiens
691 MPZL1 9019
Proximity Label-MS Homo sapiens
692 PHF5A 84844
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
693 PLP2 5355
Synthetic Lethality Homo sapiens
694 EXOSC2 23404
Negative Genetic Homo sapiens
695 TBCA 6902
Negative Genetic Homo sapiens
696 CTNNA1 1495
Proximity Label-MS Homo sapiens
697 MARS2 92935
Negative Genetic Homo sapiens
698 PML 5371
Affinity Capture-MS Homo sapiens
699 TMEM57  
Proximity Label-MS Homo sapiens
700 PABPN1 8106
Negative Genetic Homo sapiens
701 MED14  
Negative Genetic Homo sapiens
702 GNL3 26354
Negative Genetic Homo sapiens
703 DDX55  
Negative Genetic Homo sapiens
704 AFG3L2 10939
Negative Genetic Homo sapiens
705 ZNF493  
Synthetic Lethality Homo sapiens
706 UROD 7389
Negative Genetic Homo sapiens
707 FLVCR1 28982
Proximity Label-MS Homo sapiens
708 PAXBP1  
Negative Genetic Homo sapiens
709 EIF1AD 84285
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
710 GGA3 23163
Synthetic Lethality Homo sapiens
711 POLE  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
712 POLR2J  
Negative Genetic Homo sapiens
713 ISCA2 122961
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
714 EMC7 56851
Negative Genetic Homo sapiens
715 SKP1 6500
Negative Genetic Homo sapiens
716 WRAP53  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
717 SNUPN 10073
Negative Genetic Homo sapiens
718 CDC6  
Negative Genetic Homo sapiens
719 TKT 7086
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
720 PUF60 22827
Negative Genetic Homo sapiens
721 SPATA20  
Negative Genetic Homo sapiens
722 H2AFY 9555
Negative Genetic Homo sapiens
723 DYNC1H1 1778
Negative Genetic Homo sapiens
724 FAM219A 203259
Proximity Label-MS Homo sapiens
725 XPO5 57510
Negative Genetic Homo sapiens
726 ATP6V0C 527
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
727 ALYREF 10189
Negative Genetic Homo sapiens
728 PHACTR4 65979
Proximity Label-MS Homo sapiens
729 SUPT6H 6830
Negative Genetic Homo sapiens
730 POLR3B 55703
Negative Genetic Homo sapiens
731 PGM3 5238
Negative Genetic Homo sapiens
732 PDE4DIP 9659
Two-hybrid Homo sapiens
733 PRPF4 9128
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
734 SLCO3A1 28232
Proximity Label-MS Homo sapiens
735 VANGL1 81839
Proximity Label-MS Homo sapiens
736 SNRPA1 6627
Negative Genetic Homo sapiens
737 DNMT1 1786
Negative Genetic Homo sapiens
738 FAM92A1  
Proximity Label-MS Homo sapiens
739 NOP10 55505
Negative Genetic Homo sapiens
740 RTEL1 51750
Negative Genetic Homo sapiens
741 GNAI3 2773
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
742 PTPRF 5792
Proximity Label-MS Homo sapiens
743 DENR 8562
Synthetic Lethality Homo sapiens
744 FAM171A2 284069
Proximity Label-MS Homo sapiens
745 VARS 7407
Negative Genetic Homo sapiens
746 FAM71E1  
Synthetic Lethality Homo sapiens
747 MAT2A 4144
Negative Genetic Homo sapiens
748 TRRAP 8295
Negative Genetic Homo sapiens
749 NOS1AP  
Proximity Label-MS Homo sapiens
750 PRELID1  
Negative Genetic Homo sapiens
751 TARDBP 23435
Negative Genetic Homo sapiens
752 FGD1  
Proximity Label-MS Homo sapiens
753 NUP62 23636
Negative Genetic Homo sapiens
754 DTNA  
Proximity Label-MS Homo sapiens
755 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
756 ROCK2 9475
Proximity Label-MS Homo sapiens
757 UQCR10 29796
Negative Genetic Homo sapiens
758 SRSF2 6427
Negative Genetic Homo sapiens
759 UBE2N 7334
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
760 OXSM  
Negative Genetic Homo sapiens
761 RNPS1 10921
Affinity Capture-MS Homo sapiens
762 TTK 7272
Proximity Label-MS Homo sapiens
763 OGDH 4967
Negative Genetic Homo sapiens
764 TRMT112 51504
Negative Genetic Homo sapiens
765 TNIK 23043
Proximity Label-MS Homo sapiens
766 TINF2  
Negative Genetic Homo sapiens
767 NAT1 9
Synthetic Lethality Homo sapiens
768 RPLP2 6181
Negative Genetic Homo sapiens
769 ANAPC11  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
770 PAK1IP1  
Negative Genetic Homo sapiens
771 MAK  
Synthetic Lethality Homo sapiens
772 ZNF99  
Negative Genetic Homo sapiens
773 TUT1  
Negative Genetic Homo sapiens
774 ERAL1  
Negative Genetic Homo sapiens
775 CUL1 8454
Negative Genetic Homo sapiens
776 PMPCB 9512
Negative Genetic Homo sapiens
777 PPCDC  
Negative Genetic Homo sapiens
778 USP7 7874
Negative Genetic Homo sapiens
779 SLC7A11 23657
Proximity Label-MS Homo sapiens
780 LMAN1 3998
Proximity Label-MS Homo sapiens
781 RPEL1  
Negative Genetic Homo sapiens
782 PFN1 5216
Negative Genetic Homo sapiens
783 USP17L12  
Synthetic Lethality Homo sapiens
784 PHLDB2 90102
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
785 NAE1 8883
Negative Genetic Homo sapiens
786 SLC1A5 6510
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
787 PRPF8 10594
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
788 RBX1 9978
Negative Genetic Homo sapiens
789 VPS45 11311
Proximity Label-MS Homo sapiens
790 POLR3K  
Negative Genetic Homo sapiens
791 KLC1 3831
Affinity Capture-MS Homo sapiens
792 NDRG3 57446
Proximity Label-MS Homo sapiens
793 RAI14 26064
Proximity Label-MS Homo sapiens
794 ATP2B1 490
Proximity Label-MS Homo sapiens
795 PSMD14 10213
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
796 POLA2  
Negative Genetic Homo sapiens
797 SNAP47 116841
Proximity Label-MS Homo sapiens
798 NELFCD 51497
Negative Genetic Homo sapiens
799 JAM3 83700
Proximity Label-MS Homo sapiens
800 VRK1 7443
Negative Genetic Homo sapiens
801 ADD2 119
Proximity Label-MS Homo sapiens
802 PMAIP1  
Affinity Capture-MS Homo sapiens
803 NDOR1  
Negative Genetic Homo sapiens
804 SIPA1L2  
Proximity Label-MS Homo sapiens
805 MRPL51 51258
Negative Genetic Homo sapiens
806 LIN7C 55327
Synthetic Lethality Homo sapiens
807 SLC9A1 6548
Proximity Label-MS Homo sapiens
808 EXOSC5 56915
Negative Genetic Homo sapiens
809 PPP2CA 5515
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
810 NCL 4691
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
811 JAG2  
Proximity Label-MS Homo sapiens
812 UQCRC1 7384
Negative Genetic Homo sapiens
813 SLC25A19  
Negative Genetic Homo sapiens
814 SLC12A4 6560
Proximity Label-MS Homo sapiens
815 COPS7B 64708
Affinity Capture-MS Homo sapiens
816 GMPS 8833
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
817 AIMP2 7965
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
818 TICRR 90381
Negative Genetic Homo sapiens
819 NBPF14 25832
Negative Genetic Homo sapiens
820 NBPF15  
Negative Genetic Homo sapiens
821 MINK1 50488
Proximity Label-MS Homo sapiens
822 RPL32 6161
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
823 C10orf2 56652
Negative Genetic Homo sapiens
824 PSMA3 5684
Two-hybrid Homo sapiens
Negative Genetic Homo sapiens
825 NISCH 11188
Proximity Label-MS Homo sapiens
826 RPS2 6187
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
827 POP1 10940
Negative Genetic Homo sapiens
828 SEC13 6396
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
829 NUP88 4927
Negative Genetic Homo sapiens
830 EGFR 1956
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
831 HSD17B10 3028
Negative Genetic Homo sapiens
832 FARP2 9855
Proximity Label-MS Homo sapiens
833 PLEKHA7 144100
Proximity Label-MS Homo sapiens
834 GAB1  
Proximity Label-MS Homo sapiens
835 TRAPPC1 58485
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
836 RPP30 10556
Negative Genetic Homo sapiens
837 DMAP1 55929
Negative Genetic Homo sapiens
838 TAOK2 9344
Proximity Label-MS Homo sapiens
839 NOL12 79159
Negative Genetic Homo sapiens
840 KREMEN2  
Synthetic Lethality Homo sapiens
841 COCH 1690
Synthetic Growth Defect Homo sapiens
842 PPAN 56342
Negative Genetic Homo sapiens
843 NCAPG2 54892
Negative Genetic Homo sapiens
844 PODXL 5420
Proximity Label-MS Homo sapiens
845 OSBPL8 114882
Proximity Label-MS Homo sapiens
846 FTSJ3 117246
Negative Genetic Homo sapiens
847 RAE1 8480
Negative Genetic Homo sapiens
848 WDR47  
Synthetic Lethality Homo sapiens
849 EEPD1 80820
Proximity Label-MS Homo sapiens
850 TACC3  
Negative Genetic Homo sapiens
851 GATAD2A 54815
Affinity Capture-MS Homo sapiens
852 KRT18 3875
Negative Genetic Homo sapiens
853 GNPNAT1 64841
Negative Genetic Homo sapiens
854 POLR2F  
Negative Genetic Homo sapiens
855 UBA5 79876
Negative Genetic Homo sapiens
856 PGRMC1 10857
Proximity Label-MS Homo sapiens
857 EPB42 2038
Reconstituted Complex Homo sapiens
858 SF3A1 10291
Negative Genetic Homo sapiens
859 TBCC 6903
Negative Genetic Homo sapiens
860 SLCO4A1 28231
Proximity Label-MS Homo sapiens
861 SEC23B 10483
Synthetic Lethality Homo sapiens
862 SEMA3C 10512
Synthetic Lethality Homo sapiens
863 SRP19 6728
Negative Genetic Homo sapiens
864 SNAP25 6616
Proximity Label-MS Homo sapiens
865 MRPS21  
Negative Genetic Homo sapiens
866 TRIP12 9320
Affinity Capture-MS Homo sapiens
867 NOC2L 26155
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
868 GFM1 85476
Negative Genetic Homo sapiens
869 POLR3D  
Negative Genetic Homo sapiens
870 DYNLRB1 83658
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
871 ARF1 375
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
872 ANK3  
Proximity Label-MS Homo sapiens
873 DLD 1738
Negative Genetic Homo sapiens
874 TIMM13 26517
Synthetic Lethality Homo sapiens
875 RAB23 51715
Proximity Label-MS Homo sapiens
876 CHMP2A 27243
Negative Genetic Homo sapiens
877 ATP6V1B2 526
Negative Genetic Homo sapiens
878 DLG5 9231
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
879 CLCN7 1186
Proximity Label-MS Homo sapiens
880 SNRPE 6635
Negative Genetic Homo sapiens
881 OCLN 100506658
Proximity Label-MS Homo sapiens
882 DNAJC8 22826
Negative Genetic Homo sapiens
883 ATP6V1A 523
Negative Genetic Homo sapiens
884 MRPL17  
Negative Genetic Homo sapiens
885 MCM3 4172
Negative Genetic Homo sapiens
886 PLCL2 23228
Proximity Label-MS Homo sapiens
887 SDAD1  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
888 MFN1 55669
Synthetic Lethality Homo sapiens
889 PAK2 5062
Proximity Label-MS Homo sapiens
890 ADGRL2 23266
Proximity Label-MS Homo sapiens
891 RPS19 6223
Synthetic Growth Defect Homo sapiens
Negative Genetic Homo sapiens
892 ROBO1 6091
Proximity Label-MS Homo sapiens
893 EPS8 2059
Proximity Label-MS Homo sapiens
894 MBTPS2  
Negative Genetic Homo sapiens
895 ANKS1A 23294
Proximity Label-MS Homo sapiens
896 GTF2H2  
Negative Genetic Homo sapiens
897 INTS9 55756
Negative Genetic Homo sapiens
898 CAPZB 832
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
899 GTF2H2C  
Negative Genetic Homo sapiens
900 RUVBL1 8607
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
901 MLLT4 4301
Proximity Label-MS Homo sapiens
902 MBD3L5 284428
Synthetic Lethality Homo sapiens
903 COPB2 9276
Negative Genetic Homo sapiens
904 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
905 SUPV3L1 6832
Negative Genetic Homo sapiens
906 MCM6 4175
Negative Genetic Homo sapiens
907 MFAP3L  
Proximity Label-MS Homo sapiens
908 RPIA 22934
Negative Genetic Homo sapiens
909 NHP2 55651
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
910 PKN2 5586
Proximity Label-MS Homo sapiens
911 EHD1 10938
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
912 PSTK  
Negative Genetic Homo sapiens
913 NUP155 9631
Negative Genetic Homo sapiens
914 BRIX1 55299
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
915 ZDHHC17 23390
Two-hybrid Homo sapiens
916 ITGA3 3675
Negative Genetic Homo sapiens
917 IRS4 8471
Proximity Label-MS Homo sapiens
918 ATP5A1 498
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
919 SCFD1 23256
Synthetic Lethality Homo sapiens
920 PSMB4 5692
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
921 ZFYVE16  
Proximity Label-MS Homo sapiens
922 TAF10 6881
Negative Genetic Homo sapiens
923 COPE 11316
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
924 CLNS1A 1207
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
925 TBC1D3B  
Negative Genetic Homo sapiens
926 RSRC2  
Negative Genetic Homo sapiens
927 RTF1 23168
Negative Genetic Homo sapiens
928 KDSR 2531
Synthetic Lethality Homo sapiens
929 USP8 9101
Negative Genetic Homo sapiens
930 CHMP4B 128866
Negative Genetic Homo sapiens
931 NUMB 8650
Proximity Label-MS Homo sapiens
932 DIRAS3  
Synthetic Growth Defect Homo sapiens
933 RRM1 6240
Negative Genetic Homo sapiens
934 SYNJ1 8867
Proximity Label-MS Homo sapiens
935 TPI1 7167
Negative Genetic Homo sapiens
936 U2AF2 11338
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
937 MYBL2 4605
Negative Genetic Homo sapiens
938 NLGN1  
Proximity Label-MS Homo sapiens
939 RPN1 6184
Proximity Label-MS Homo sapiens
940 COPS3 8533
Negative Genetic Homo sapiens
941 PIK3R1 5295
Proximity Label-MS Homo sapiens
942 DHX9 1660
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
943 COX7B 1349
Synthetic Lethality Homo sapiens
944 LZTR1 8216
Proximity Label-MS Homo sapiens
945 MED31  
Negative Genetic Homo sapiens
946 FUBP1 8880
Negative Genetic Homo sapiens
947 GNG5 2787
Affinity Capture-MS Homo sapiens
948 RPL11 6135
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
949 WDR46  
Negative Genetic Homo sapiens
950 DUSP22  
Affinity Capture-MS Homo sapiens
951 NUP37 79023
Synthetic Lethality Homo sapiens
952 CCNA2 890
Negative Genetic Homo sapiens
953 CDC73  
Negative Genetic Homo sapiens
954 STON1-GTF2A1L  
Proximity Label-MS Homo sapiens
955 RNMT 8731
Negative Genetic Homo sapiens
956 EEF2 1938
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
957 MRPS14  
Negative Genetic Homo sapiens
958 SIRPA 140885
Proximity Label-MS Homo sapiens
959 METTL16 79066
Negative Genetic Homo sapiens
960 DCAF13 25879
Negative Genetic Homo sapiens
961 OSGEP 55644
Negative Genetic Homo sapiens
962 RIC1 57589
Negative Genetic Homo sapiens
963 RBFOX1 54715
Synthetic Lethality Homo sapiens
964 NADK 65220
Negative Genetic Homo sapiens
965 AP2M1 1173
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
966 OSBPL11 114885
Proximity Label-MS Homo sapiens
967 VPS37A 137492
Negative Genetic Homo sapiens
968 RPL36 25873
Negative Genetic Homo sapiens
969 Flnb 286940
Affinity Capture-MS Mus musculus
970 PTPN13 5783
Proximity Label-MS Homo sapiens
971 GNB2 2783
Affinity Capture-MS Homo sapiens
972 TC2N 123036
Proximity Label-MS Homo sapiens
973 FDPS 2224
Synthetic Lethality Homo sapiens
974 KIAA0391  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
975 COA5  
Negative Genetic Homo sapiens
976 EPB41 2035
Proximity Label-MS Homo sapiens
977 PPP6C 5537
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
978 ACTB 60
Negative Genetic Homo sapiens
979 FLII 2314
Affinity Capture-MS Homo sapiens
980 SEH1L 81929
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
981 SEPT7 989
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
982 CD96  
Synthetic Lethality Homo sapiens
983 CDC7  
Negative Genetic Homo sapiens
984 HLA-A 3105
Proximity Label-MS Homo sapiens
985 ROCK1 6093
Proximity Label-MS Homo sapiens
986 XRCC5 7520
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
987 VPS25 84313
Negative Genetic Homo sapiens
988 LRRC18  
Negative Genetic Homo sapiens
989 EIF2S1 1965
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
990 DDX50 79009
Two-hybrid Homo sapiens
991 POP7  
Negative Genetic Homo sapiens
992 FNBP4  
Negative Genetic Homo sapiens
993 TMED10 10972
Negative Genetic Homo sapiens
994 CCT8 10694
Synthetic Lethality Homo sapiens
995 TOPBP1 11073
Negative Genetic Homo sapiens
996 GPI 2821
Synthetic Lethality Homo sapiens
997 NLE1 54475
Negative Genetic Homo sapiens
998 LONP1 9361
Negative Genetic Homo sapiens
999 DNA2  
Negative Genetic Homo sapiens
1000 RPA1 6117
Negative Genetic Homo sapiens
1001 PCBP1 5093
Negative Genetic Homo sapiens
1002 VAMP4 8674
Proximity Label-MS Homo sapiens
1003 LENG8  
Negative Genetic Homo sapiens
1004 EFNB1 1947
Proximity Label-MS Homo sapiens
1005 HSPB1 3315
Affinity Capture-MS Homo sapiens
1006 MTHFD1 4522
Negative Genetic Homo sapiens
1007 SLC38A7 55238
Negative Genetic Homo sapiens
1008 PGP 283871
Negative Genetic Homo sapiens
1009 MED18  
Negative Genetic Homo sapiens
1010 MBNL1 4154
Negative Genetic Homo sapiens
1011 LSM7  
Negative Genetic Homo sapiens
1012 INF2 64423
Proximity Label-MS Homo sapiens
1013 COA6  
Negative Genetic Homo sapiens
1014 PMVK 10654
Synthetic Lethality Homo sapiens
1015 TRMT5  
Negative Genetic Homo sapiens
1016 SPAG1 6674
Proximity Label-MS Homo sapiens
1017 RAB7A 7879
Proximity Label-MS Homo sapiens
1018 LRP2 4036
Proximity Label-MS Homo sapiens
1019 SMG1 23049
Negative Genetic Homo sapiens
1020 TAF1C  
Negative Genetic Homo sapiens
1021 UHRF1 29128
Negative Genetic Homo sapiens
1022 YWHAE 7531
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
1023 UBA6 55236
Negative Genetic Homo sapiens
1024 SAP18 10284
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1025 NOTCH1 4851
Proximity Label-MS Homo sapiens
1026 USO1 8615
Negative Genetic Homo sapiens
1027 NRBP1 29959
Negative Genetic Homo sapiens
1028 INTS4  
Negative Genetic Homo sapiens
1029 MCRS1  
Negative Genetic Homo sapiens
1030 PRIM2 5558
Negative Genetic Homo sapiens
1031 RPS6KA5 9252
Synthetic Lethality Homo sapiens
1032 ARHGAP21 57584
Proximity Label-MS Homo sapiens
1033 SLC29A1 2030
Proximity Label-MS Homo sapiens
1034 ANKLE2 23141
Negative Genetic Homo sapiens
1035 POT1  
Synthetic Lethality Homo sapiens
1036 PSMD6 9861
Negative Genetic Homo sapiens
1037 VAPA 9218
Proximity Label-MS Homo sapiens
1038 DCTN6 10671
Negative Genetic Homo sapiens
1039 IPO7 10527
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
1040 TNPO1 3842
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1041 PSMD11 5717
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1042 CSNK1G2 1455
Proximity Label-MS Homo sapiens
1043 NFYC 4802
Negative Genetic Homo sapiens
1044 INTS10  
Negative Genetic Homo sapiens
1045 MRPL10 124995
Negative Genetic Homo sapiens
1046 LNPEP 4012
Proximity Label-MS Homo sapiens
1047 SLC30A4 7782
Proximity Label-MS Homo sapiens
1048 USP31 57478
Proximity Label-MS Homo sapiens
1049 WDR36 134430
Negative Genetic Homo sapiens
1050 ILF2 3608
Negative Genetic Homo sapiens
1051 KIAA1429 25962
Negative Genetic Homo sapiens
1052 TOP2A 7153
Negative Genetic Homo sapiens
1053 IRF2BP1 26145
Negative Genetic Homo sapiens
1054 UXS1 80146
Negative Genetic Homo sapiens
1055 MARK2 2011
Synthetic Lethality Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
1056 MRPL20 55052
Negative Genetic Homo sapiens
1057 CDK14 5218
Proximity Label-MS Homo sapiens
1058 WDR20 91833
Proximity Label-MS Homo sapiens
1059 TAF2  
Negative Genetic Homo sapiens
1060 COPS5 10987
Negative Genetic Homo sapiens
1061 HGS 9146
Negative Genetic Homo sapiens
1062 LTA4H 4048
Synthetic Growth Defect Homo sapiens
Synthetic Lethality Homo sapiens
1063 ZGPAT  
Synthetic Lethality Homo sapiens
1064 ORC5  
Negative Genetic Homo sapiens
1065 PSMC6 5706
Negative Genetic Homo sapiens
1066 STX18 53407
Negative Genetic Homo sapiens
1067 WDR74 54663
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1068 ABCE1 6059
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1069 ATP5O 539
Synthetic Lethality Homo sapiens
1070 LRRC4B  
Proximity Label-MS Homo sapiens
1071 TULP3 7289
Proximity Label-MS Homo sapiens
1072 CDC27 996
Proximity Label-MS Homo sapiens
Negative Genetic Homo sapiens
1073 INTS6 26512
Negative Genetic Homo sapiens
1074 CCDC115 84317
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1075 CDCA8 55143
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1076 WDR18 57418
Negative Genetic Homo sapiens
1077 ARL1 400
Affinity Capture-MS Homo sapiens
1078 ERBB2 2064
Proximity Label-MS Homo sapiens
1079 ADSS 159
Negative Genetic Homo sapiens
1080 ZNF626  
Negative Genetic Homo sapiens
1081 ATP6AP1 537
Negative Genetic Homo sapiens
1082 NARS 4677
Negative Genetic Homo sapiens
1083 CTCF  
Synthetic Lethality Homo sapiens
1084 RALGDS  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
1085 FCF1  
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
1086 IGF1R 3480
Affinity Capture-MS Homo sapiens