Gene description for ATP5L
Gene name
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
Gene symbol
ATP5L
Other names/aliases
ATP5JG
Species
Homo sapiens
Database cross references - ATP5L
ExoCarta
ExoCarta_10632
Entrez Gene
10632
HGNC
14247
UniProt
O75964
ATP5L identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells
17956143
Squamous carcinoma cells
20124223
Gene ontology annotations for ATP5L
Experiment description of studies that identified ATP5L in exosomes
1
Experiment ID
20
ISEV standards
✔
EM
EV Biophysical techniques
✔
HSP90
EV Cytosolic markers
✔
CD63|CD81|LAMP1
EV Membrane markers
✔
GOLGA2|cytochrome c
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
17956143
Organism
Homo sapiens
Experiment description
Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors
Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name
JPR
Publication year
2007
Sample
Colorectal cancer cells
Sample name
HT29
Isolation/purification methods
Differential centrifugation Sucrose density gradient Diafiltration
Flotation density
1.16 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
2
Experiment ID
191
ISEV standards
✘
EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD81|CD9
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK.
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for ATP5L
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SAP18
10284
Affinity Capture-MS
Homo sapiens
2
PHLDA3
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which ATP5L is involved