Gene ontology annotations for LAMTOR3
Experiment description of studies that identified LAMTOR3 in exosomes
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
363
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
6
Experiment ID
364
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
7
Experiment ID
365
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
8
Experiment ID
255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
G1
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
9
Experiment ID
256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
501mel
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
10
Experiment ID
257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
Daju
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
11
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
12
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
13
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
14
Experiment ID
63
MISEV standards
✘
Biophysical techniques
✔
AQP2
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
"Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for LAMTOR3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ATP6V1B2
526
Co-fractionation
Homo sapiens
2
MTCH1
23787
Co-fractionation
Homo sapiens
3
QARS
5859
Two-hybrid
Homo sapiens
4
C19orf70
Co-fractionation
Homo sapiens
5
NDUFB5
4711
Co-fractionation
Homo sapiens
6
NUPL1
9818
Co-fractionation
Homo sapiens
7
RRAGD
58528
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
8
VAMP2
6844
Co-fractionation
Homo sapiens
9
PTPN1
5770
Co-fractionation
Homo sapiens
10
LPCAT1
79888
Co-fractionation
Homo sapiens
11
TOMM22
56993
Co-fractionation
Homo sapiens
12
RPS18
6222
Co-fractionation
Homo sapiens
13
PTRH2
51651
Co-fractionation
Homo sapiens
14
CPNE6
9362
Two-hybrid
Homo sapiens
15
NDUFB9
4715
Co-fractionation
Homo sapiens
16
WDR83
Affinity Capture-Western
Homo sapiens
17
APOL6
Two-hybrid
Homo sapiens
18
STX7
8417
Affinity Capture-MS
Homo sapiens
19
RAB21
23011
Co-fractionation
Homo sapiens
20
TMEM192
201931
Affinity Capture-MS
Homo sapiens
21
CDC27
996
Affinity Capture-MS
Homo sapiens
22
MRPL39
54148
Co-fractionation
Homo sapiens
23
TUBA3C
7278
Affinity Capture-MS
Homo sapiens
24
TOMM40
10452
Co-fractionation
Homo sapiens
25
LAMTOR4
389541
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
26
TFCP2
7024
Affinity Capture-MS
Homo sapiens
27
BHMT
635
Two-hybrid
Homo sapiens
28
UQCRQ
27089
Co-fractionation
Homo sapiens
29
MRPL47
57129
Co-fractionation
Homo sapiens
30
NIF3L1
60491
Two-hybrid
Homo sapiens
31
RPL19
6143
Cross-Linking-MS (XL-MS)
Homo sapiens
32
LAMTOR1
55004
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Affinity Capture-MS
Homo sapiens
33
MAPK1
5594
Reconstituted Complex
Homo sapiens
Co-fractionation
Homo sapiens
34
NNT
23530
Co-fractionation
Homo sapiens
35
MPV17
4358
Co-fractionation
Homo sapiens
36
MAPK3
5595
Affinity Capture-Western
Homo sapiens
37
COX15
1355
Co-fractionation
Homo sapiens
38
SLC38A9
Affinity Capture-MS
Homo sapiens
39
NDUFB7
4713
Co-fractionation
Homo sapiens
40
RAB14
51552
Co-fractionation
Homo sapiens
41
TMEM55B
90809
Affinity Capture-MS
Homo sapiens
42
RALA
5898
Co-fractionation
Homo sapiens
43
RRAGB
10325
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
44
VRK1
7443
Affinity Capture-MS
Homo sapiens
45
UQCRFS1P1
Co-fractionation
Homo sapiens
46
TUBA1C
84790
Cross-Linking-MS (XL-MS)
Homo sapiens
47
YAP1
10413
Affinity Capture-MS
Homo sapiens
48
MRPL51
51258
Co-fractionation
Homo sapiens
49
NDUFA2
4695
Co-fractionation
Homo sapiens
50
MBD2
8932
Two-hybrid
Homo sapiens
51
MRPL22
Co-fractionation
Homo sapiens
52
PICALM
8301
Co-fractionation
Homo sapiens
53
ATP6V1E1
529
Co-fractionation
Homo sapiens
54
ZBTB43
Co-fractionation
Homo sapiens
55
ZSCAN4
Two-hybrid
Homo sapiens
56
RRAGA
10670
Affinity Capture-MS
Homo sapiens
57
MRPS35
60488
Co-fractionation
Homo sapiens
58
RALB
5899
Co-fractionation
Homo sapiens
59
ADAMTS10
81794
Two-hybrid
Homo sapiens
60
LAMP1
3916
Affinity Capture-MS
Homo sapiens
61
RPGRIP1
Cross-Linking-MS (XL-MS)
Homo sapiens
62
EGFR
1956
Negative Genetic
Homo sapiens
63
SPCS2
9789
Co-fractionation
Homo sapiens
64
LAMTOR5
10542
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
65
TGM7
Two-hybrid
Homo sapiens
66
TOMM70A
9868
Co-fractionation
Homo sapiens
67
PRR3
Co-fractionation
Homo sapiens
68
UBR1
197131
Two-hybrid
Homo sapiens
69
CEBPZ
Two-hybrid
Homo sapiens
70
TMCO1
54499
Co-fractionation
Homo sapiens
71
ATP6V1A
523
Co-fractionation
Homo sapiens
72
MSLN
10232
Co-fractionation
Homo sapiens
73
LOH12CR1
118426
Affinity Capture-MS
Homo sapiens
74
RHOB
388
Co-fractionation
Homo sapiens
75
MSN
4478
Cross-Linking-MS (XL-MS)
Homo sapiens
76
TSR1
55720
Co-fractionation
Homo sapiens
77
RAB31
11031
Co-fractionation
Homo sapiens
78
RRAGC
64121
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
79
CD46
4179
Co-fractionation
Homo sapiens
80
PEF1
553115
Co-fractionation
Homo sapiens
81
UBXN4
23190
Cross-Linking-MS (XL-MS)
Homo sapiens
82
Osgep
Affinity Capture-MS
Mus musculus
83
ILF2
3608
Co-fractionation
Homo sapiens
84
NUFIP2
57532
Affinity Capture-Western
Homo sapiens
85
MRPL43
84545
Co-fractionation
Homo sapiens
86
RPTOR
57521
Affinity Capture-MS
Homo sapiens
87
POTEE
445582
Affinity Capture-MS
Homo sapiens
88
LAMTOR2
28956
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Co-crystal Structure
Homo sapiens
Co-crystal Structure
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
89
ELAVL1
1994
Affinity Capture-RNA
Homo sapiens
90
SNAPIN
23557
Affinity Capture-MS
Homo sapiens
91
PUF60
22827
Co-fractionation
Homo sapiens
92
MAP2K1
5604
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
93
SSBP1
6742
Co-fractionation
Homo sapiens
94
C10orf32
Affinity Capture-MS
Homo sapiens
95
MOV10
4343
Affinity Capture-RNA
Homo sapiens
96
RNMTL1
Co-fractionation
Homo sapiens
97
MRPS9
64965
Co-fractionation
Homo sapiens
98
IBTK
25998
Two-hybrid
Homo sapiens
99
RAB7A
7879
Affinity Capture-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
100
RPS7
6201
Co-fractionation
Homo sapiens
101
PDE4DIP
9659
Two-hybrid
Homo sapiens
102
KRAS
3845
Negative Genetic
Homo sapiens
103
RAB5C
5878
Co-fractionation
Homo sapiens
104
NDUFB11
54539
Co-fractionation
Homo sapiens
105
VDAC3
7419
Co-fractionation
Homo sapiens
106
IRS1
3667
Co-fractionation
Homo sapiens
107
RAB2A
5862
Co-fractionation
Homo sapiens
108
DDX28
Co-fractionation
Homo sapiens
109
C17orf59
54785
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
110
NDUFB4
4710
Co-fractionation
Homo sapiens
View the network
image/svg+xml
Pathways in which LAMTOR3 is involved