Gene description for HSPA8
Gene name heat shock 70kDa protein 8
Gene symbol HSPA8
Other names/aliases HEL-33
HEL-S-72p
HSC54
HSC70
HSC71
HSP71
HSP73
HSPA10
LAP-1
LAP1
NIP71
Species Homo sapiens
 Database cross references - HSPA8
ExoCarta ExoCarta_3312
Vesiclepedia VP_3312
Entrez Gene 3312
HGNC 5241
MIM 600816
UniProt P11142  
 HSPA8 identified in sEVs derived from the following tissue/cell type
B cells 12519789    
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 19415654    
Breast milk 17641064    
Breast milk 17641064    
Breast milk 21235781    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Keratinocytes 18452139    
Keratinocytes 19530224    
Keratinocytes 19530224    
Malignant ascites 12147373    
Melanoma cells 15478216    
Melanoma cells 11231627    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Mesothelioma cells 15111327    
Nasopharyngeal carcinoma cells 21059916    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Saliva 19199708    
Serum 19109410    
Thymus 23844026    
Urine 15326289    
Urine 19056867    
Urine 21595033    
Urine 21595033    
Urine 21595033    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for HSPA8
Molecular Function
    G protein-coupled receptor binding GO:0001664 IPI
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    ATP hydrolysis activity GO:0016887 IBA
    ATP hydrolysis activity GO:0016887 NAS
    ATP hydrolysis activity GO:0016887 TAS
    enzyme binding GO:0019899 IPI
    MHC class II protein complex binding GO:0023026 HDA
    protein-macromolecule adaptor activity GO:0030674 IDA
    protein-macromolecule adaptor activity GO:0030674 IPI
    heat shock protein binding GO:0031072 IBA
    heat shock protein binding GO:0031072 IPI
    ubiquitin protein ligase binding GO:0031625 IPI
    protein folding chaperone GO:0044183 IBA
    cadherin binding GO:0045296 HDA
    receptor ligand activity GO:0048018 IDA
    unfolded protein binding GO:0051082 IDA
    protein-folding chaperone binding GO:0051087 IPI
    C3HC4-type RING finger domain binding GO:0055131 IPI
    ATP-dependent protein disaggregase activity GO:0140545 IDA
    protein carrier chaperone GO:0140597 TAS
    ATP-dependent protein folding chaperone GO:0140662 IEA
Biological Process
    mRNA splicing, via spliceosome GO:0000398 NAS
    protein folding GO:0006457 NAS
    response to unfolded protein GO:0006986 NAS
    signal transduction GO:0007165 IEA
    cellular response to starvation GO:0009267 TAS
    positive regulation of cell migration GO:0030335 IDA
    regulation of protein stability GO:0031647 IMP
    protein refolding GO:0042026 IBA
    protein refolding GO:0042026 IDA
    regulation of protein-containing complex assembly GO:0043254 TAS
    negative regulation of DNA-templated transcription GO:0045892 IDA
    ATP metabolic process GO:0046034 IDA
    chaperone cofactor-dependent protein refolding GO:0051085 IBA
    membrane organization GO:0061024 TAS
    regulation of protein complex stability GO:0061635 ISS
    chaperone-mediated autophagy GO:0061684 ISS
    chaperone-mediated autophagy GO:0061684 TAS
    protein targeting to lysosome involved in chaperone-mediated autophagy GO:0061740 IDA
    protein targeting to lysosome involved in chaperone-mediated autophagy GO:0061740 IMP
    protein targeting to lysosome involved in chaperone-mediated autophagy GO:0061740 TAS
    cellular response to steroid hormone stimulus GO:0071383 TAS
    clathrin coat disassembly GO:0072318 IBA
    clathrin coat disassembly GO:0072318 IDA
    negative regulation of NLRP3 inflammasome complex assembly GO:1900226 IDA
    negative regulation of supramolecular fiber organization GO:1902904 IDA
    regulation of protein import GO:1904589 TAS
    chaperone-mediated autophagy translocation complex disassembly GO:1904764 ISS
Subcellular Localization
    Prp19 complex GO:0000974 IDA
    Prp19 complex GO:0000974 IPI
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 HDA
    extracellular space GO:0005615 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    spliceosomal complex GO:0005681 IPI
    nucleolus GO:0005730 IEA
    cytoplasm GO:0005737 IBA
    lysosomal membrane GO:0005765 IDA
    lysosomal membrane GO:0005765 ISS
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    focal adhesion GO:0005925 HDA
    membrane GO:0016020 HDA
    secretory granule lumen GO:0034774 TAS
    melanosome GO:0042470 IEA
    lysosomal lumen GO:0043202 TAS
    clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane GO:0061202 TAS
    extracellular exosome GO:0070062 HDA
    extracellular exosome GO:0070062 IDA
    blood microparticle GO:0072562 HDA
    lumenal side of lysosomal membrane GO:0098575 TAS
    protein folding chaperone complex GO:0101031 IPI
    ficolin-1-rich granule lumen GO:1904813 TAS
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified HSPA8 in sEVs
1
Experiment ID 11
MISEV standards
✘ Biophysical techniques
✔
HSC70|HSP90|MHCII|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [MALDI TOF]
PubMed ID 12519789    
Organism Homo sapiens
Experiment description Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.
Authors "Wubbolts R, Leckie RS, Veenhuizen PT, Schwarzmann G, Mobius W, Hoernschemeyer J, Slot JW, Geuze HJ, Stoorvogel W"
Journal name JBC
Publication year 2003
Sample B cells
Sample name RN (HLA-DR15+)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [MALDI TOF]
Mass spectrometry [QTOF]
Western blotting
Thin layer chromatography
HPLC
2
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
5
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
6
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 65
MISEV standards
✘ Biophysical techniques
✔
HSP60|HSP27|GAPDH|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19415654    
Organism Homo sapiens
Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
Authors "Staubach S, Razawi H, Hanisch FG."
Journal name PROTEOMICS
Publication year 2009
Sample Breast cancer cells
Sample name MCF-7
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
11
Experiment ID 46
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|MHCII|CD81|CD86
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors "Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Colostrum
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
12
Experiment ID 48
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|CD86|MHCII
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors "Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Mature milk
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
13
Experiment ID 124
MISEV standards
✔
IEM|EM
Biophysical techniques
✔
HSC70|CD63|CD9|CD81
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 21235781    
Organism Homo sapiens
Experiment description "Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages."
Authors "Lasser C, Alikhani VS, Ekstrom K, Eldh M, Paredes PT, Bossios A, Sjostrand M, Gabrielsson S, Lotvall J, Valadi H."
Journal name JTM
Publication year 2011
Sample Breast milk
Sample name Breast milk - Normal
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study FACS
Immunoelectron Microscopy
Western blotting
14
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
19
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
20
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
22
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
23
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
24
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
25
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
26
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
32
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
33
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
34
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
35
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
36
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
37
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
38
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
39
Experiment ID 32
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|LAMP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 18452139    
Organism Homo sapiens
Experiment description Primary human keratinocytes externalize stratifin protein via exosomes.
Authors "RChavez-Muñoz C, Morse J, Kilani R, Ghahary A"
Journal name JCB
Publication year 2008
Sample Keratinocytes
Sample name Keratinocytes
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
40
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
41
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
42
Experiment ID 56
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|MHCI|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 12147373    
Organism Homo sapiens
Experiment description Malignant effusions and immunogenic tumour-derived exosomes.
Authors "Andre F, Schartz NE, Movassagh M, Flament C, Pautier P, Morice P, Pomel C, Lhomme C, Escudier B, Le Chevalier T, Tursz T, Amigorena S, Raposo G, Angevin E, Zitvogel L"
Journal name LANCET
Publication year 2002
Sample Malignant ascites
Sample name Malignant ascites
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
43
Experiment ID 12
MISEV standards
✔
EM
Biophysical techniques
✔
MHCI
Enriched markers
✔
CANX|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15478216    
Organism Homo sapiens
Experiment description Proteomic analysis of melanoma-derived exosomes by two-dimensional polyacrylamide gel electrophoresis and mass spectrometry.
Authors "Mears R, Craven RA, Hanrahan S, Totty N, Upton C, Young SL, Patel P, Selby PJ, Banks RE"
Journal name PROTEOMICS
Publication year 2004
Sample Melanoma cells
Sample name MeWo
SK-MEL-28
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.20 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [4700 Proteomics Analyzer]
Western blotting
44
Experiment ID 24
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 11231627    
Organism Homo sapiens
Experiment description Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.
Authors "Wolfers J, Lozier A, Raposo G, Regnault A, Thery C, Masurier C, Flament C, Pouzieux S, Faure F, Tursz T, Angevin E, Amigorena S, Zitvogel L"
Journal name NM
Publication year 2001
Sample Melanoma cells
Sample name Fon
Mel-888
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
45
Experiment ID 200
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
46
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
47
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
49
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
51
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
52
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
53
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
54
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
55
Experiment ID 25
MISEV standards
✔
IEM
Biophysical techniques
✔
HSP90|beta-tubulin
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 15111327    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes secreted by human mesothelioma cells.
Authors "Hegmans JP, Bard MP, Hemmes A, Luider TM, Kleijmeer MJ, Prins JB, Zitvogel L, Burgers SA, Hoogsteden HC, Lambrecht BN."
Journal name AJP
Publication year 2004
Sample Mesothelioma cells
Sample name PMR-MM7
PMR-MM8
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
56
Experiment ID 125
MISEV standards
✘ Biophysical techniques
✔
HSC70|GAPDH|FLOT2
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 21059916    
Organism Homo sapiens
Experiment description Human tumor virus utilizes exosomes for intercellular communication.
Authors "Meckes DG Jr, Shair KH, Marquitz AR, Kung CP, Edwards RH, Raab-Traub N."
Journal name PNAS
Publication year 2010
Sample Nasopharyngeal carcinoma cells
Sample name C666
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
57
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
58
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
59
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
60
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
61
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
62
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
63
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
64
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
65
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
66
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
67
Experiment ID 143
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
68
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
69
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
70
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
71
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
72
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
73
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
74
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
75
Experiment ID 29
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 19109410    
Organism Homo sapiens
Experiment description Proteomic and immunologic analyses of brain tumor exosomes.
Authors "Graner MW, Alzate O, Dechkovskaia AM, Keene JD, Sampson JH, Mitchell DA, Bigner DD"
Journal name FASEB
Publication year 2008
Sample Serum
Sample name Serum - Brain tumor
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
76
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
77
Experiment ID 13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
78
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
79
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
80
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
81
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
82
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
83
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HSPA8
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CITED1 4435
Affinity Capture-Western Homo sapiens
Phenotypic Suppression Homo sapiens
2 TUSC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 HDLBP 3069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 NPEPPS 9520
Affinity Capture-MS Homo sapiens
5 ISG15 9636
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
6 FDPS 2224
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
7 TUBB2A 7280
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 ARHGEF2 9181
Affinity Capture-MS Homo sapiens
9 DGCR14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 MCM4 4173
Affinity Capture-MS Homo sapiens
11 SLFN11 91607
Affinity Capture-MS Homo sapiens
12 UBL4A 8266
Affinity Capture-MS Homo sapiens
13 NYNRIN  
Cross-Linking-MS (XL-MS) Homo sapiens
14 PACSIN1  
Affinity Capture-MS Homo sapiens
15 SHC1 6464
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 AHR 196
Affinity Capture-MS Homo sapiens
17 CCNI2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 PRPF8 10594
Affinity Capture-MS Homo sapiens
19 RIN3  
Affinity Capture-MS Homo sapiens
20 SKI 6497
Affinity Capture-MS Homo sapiens
21 TRIM26 7726
Affinity Capture-MS Homo sapiens
22 ATP13A2  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
23 CRK 1398
Affinity Capture-MS Homo sapiens
24 FCRL3  
Affinity Capture-MS Homo sapiens
25 DNAJB2 3300
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 EBNA-LP  
Affinity Capture-Western
Co-purification
Affinity Capture-MS
27 GAK 2580
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 BRCA1 672
Two-hybrid Homo sapiens
29 WNK1 65125
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 MAP4 4134
Co-fractionation Homo sapiens
31 UBE3A 7337
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
32 NMRAL1 57407
Affinity Capture-MS Homo sapiens
33 SLC25A1 6576
Affinity Capture-MS Homo sapiens
34 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
35 VHL  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
36 LOXL4 84171
Affinity Capture-MS Homo sapiens
37 ACTB 60
Co-fractionation Homo sapiens
38 SBNO1 55206
Affinity Capture-MS Homo sapiens
39 FKBP15 23307
Affinity Capture-MS Homo sapiens
40 GCN1L1 10985
Co-fractionation Homo sapiens
41 VASP 7408
Affinity Capture-MS Homo sapiens
42 TTC30B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 CENPA  
Co-purification Homo sapiens
44 FGFR3 2261
Affinity Capture-MS Homo sapiens
45 GRB7 2886
Affinity Capture-Western Homo sapiens
46 NOA1  
Two-hybrid Homo sapiens
47 HDAC3 8841
Reconstituted Complex Homo sapiens
48 KCNJ10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 CPZ 8532
Affinity Capture-MS Homo sapiens
50 MLF1  
Affinity Capture-MS Homo sapiens
51 TRMU  
Affinity Capture-MS Homo sapiens
52 LPGAT1 9926
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 GFPT1 2673
Affinity Capture-MS Homo sapiens
54 RAF1 5894
Affinity Capture-Western Homo sapiens
55 APBB2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 ODF3  
Affinity Capture-MS Homo sapiens
57 SF3B1 23451
Co-fractionation Homo sapiens
58 ERBB3 2065
Affinity Capture-MS Homo sapiens
59 METTL22  
Affinity Capture-MS Homo sapiens
60 HDAC2 3066
Co-fractionation Homo sapiens
61 NUCKS1 64710
Co-fractionation Homo sapiens
62 PDHB 5162
Affinity Capture-MS Homo sapiens
63 TRABD 80305
Affinity Capture-MS Homo sapiens
64 CPSF7 79869
Affinity Capture-MS Homo sapiens
65 NPRL2  
Affinity Capture-MS Homo sapiens
66 HSPH1 10808
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
67 POU5F1  
Affinity Capture-MS Homo sapiens
68 GADL1  
Affinity Capture-MS Homo sapiens
69 KLHL33  
Affinity Capture-MS Homo sapiens
70 PPEF1  
Affinity Capture-MS Homo sapiens
71 RPS9 6203
Co-fractionation Homo sapiens
72 DNAJB1 3337
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
73 NUS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 KRT78 196374
Affinity Capture-MS Homo sapiens
75 FAF1 11124
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
76 SNRPD3 6634
Co-fractionation Homo sapiens
77 PELI3  
Affinity Capture-MS Homo sapiens
78 ABHD17A 81926
Affinity Capture-MS Homo sapiens
79 RSG1  
Affinity Capture-MS Homo sapiens
80 MECP2 4204
Affinity Capture-MS Homo sapiens
81 PPP6R3 55291
Co-fractionation Homo sapiens
82 AIMP2 7965
Affinity Capture-MS Homo sapiens
83 ARIH2 10425
Affinity Capture-MS Homo sapiens
84 WDR5 11091
Co-fractionation Homo sapiens
85 CCT5 22948
Affinity Capture-MS Homo sapiens
86 SOD1 6647
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
87 EEF1A1 1915
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
88 RAD23A 5886
Affinity Capture-MS Homo sapiens
89 CBX3 11335
Co-fractionation Homo sapiens
90 AKT1 207
Affinity Capture-MS Homo sapiens
91 ARFIP1 27236
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 RBMX 27316
Co-fractionation Homo sapiens
93 LRRC40 55631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 BAG5 9529
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 AURKA 6790
Affinity Capture-MS Homo sapiens
96 PHLDB2 90102
Affinity Capture-MS Homo sapiens
97 ATP2A2 488
Affinity Capture-MS Homo sapiens
98 MTCH2 23788
Affinity Capture-MS Homo sapiens
99 PSMD1 5707
Co-fractionation Homo sapiens
100 NEUROG3  
Affinity Capture-MS Homo sapiens
101 DBNL 28988
Affinity Capture-MS Homo sapiens
102 HBA2 3040
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 SLC25A20 788
Co-fractionation Homo sapiens
104 C7orf26  
Affinity Capture-MS Homo sapiens
105 CAPZA1 829
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
106 USP11 8237
Affinity Capture-MS Homo sapiens
107 MTMR11  
Affinity Capture-MS Homo sapiens
108 LUZP1 7798
Affinity Capture-MS Homo sapiens
109 ATP6V1G2  
Affinity Capture-MS Homo sapiens
110 ACOT9 23597
Affinity Capture-MS Homo sapiens
111 KLHL34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 C17orf49 124944
Affinity Capture-MS Homo sapiens
113 CCDC142  
Affinity Capture-MS Homo sapiens
114 NOD2 64127
Affinity Capture-MS Homo sapiens
115 NLRX1 79671
Affinity Capture-MS Homo sapiens
116 HEY2  
Affinity Capture-MS Homo sapiens
117 SIM2  
Affinity Capture-MS Homo sapiens
118 TUFM 7284
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
119 PFKP 5214
Affinity Capture-MS Homo sapiens
120 PBK  
Co-fractionation Homo sapiens
121 SUPT16H 11198
Co-fractionation Homo sapiens
122 UBASH3B 84959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 ESRRB  
Affinity Capture-MS Homo sapiens
124 PABPC1 26986
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
125 CDH1 999
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 TUBB 203068
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 LRRFIP1 9208
Co-fractionation Homo sapiens
128 PARD3 56288
Affinity Capture-MS Homo sapiens
129 MYH9 4627
Co-fractionation Homo sapiens
130 ACTN4 81
Co-fractionation Homo sapiens
131 OGT 8473
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
132 METTL21C  
Affinity Capture-MS Homo sapiens
133 ALKBH3  
Affinity Capture-MS Homo sapiens
134 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
135 DNAJA4 55466
Co-fractionation Homo sapiens
136 TRIM21 6737
Affinity Capture-MS Homo sapiens
137 F12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
139 ZFP91 80829
Co-fractionation Homo sapiens
140 CSNK1E 1454
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 PRKDC 5591
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
142 DDX17 10521
Affinity Capture-MS Homo sapiens
143 SHCBP1 79801
Co-fractionation Homo sapiens
144 CUL2 8453
Affinity Capture-MS Homo sapiens
145 RRP1B 23076
Affinity Capture-MS Homo sapiens
146 SON 6651
Co-fractionation Homo sapiens
147 MAPK8 5599
Two-hybrid Homo sapiens
148 NCL 4691
Co-fractionation Homo sapiens
149 KCNH5  
Affinity Capture-MS Homo sapiens
150 WDR72  
Affinity Capture-MS Homo sapiens
151 SLC12A9 56996
Affinity Capture-MS Homo sapiens
152 OSBPL7  
Affinity Capture-MS Homo sapiens
153 ID2  
Affinity Capture-MS Homo sapiens
154 PPP1R8 5511
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 ACD  
Affinity Capture-MS Homo sapiens
156 YWHAE 7531
Affinity Capture-MS Homo sapiens
157 PTGIR  
Affinity Capture-MS Homo sapiens
158 ATXN1 6310
Affinity Capture-Western Homo sapiens
159 PHLPP1  
Proximity Label-MS Homo sapiens
160 FAM189B  
Affinity Capture-MS Homo sapiens
161 DNAJB14  
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
162 HSPA5 3309
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
163 TECPR2  
Affinity Capture-MS Homo sapiens
164 TBX3 6926
Affinity Capture-MS Homo sapiens
165 WDR11 55717
Co-fractionation Homo sapiens
166 TTC26 79989
Affinity Capture-MS Homo sapiens
167 ELMO3 79767
Affinity Capture-MS Homo sapiens
168 AGBL4  
Affinity Capture-MS Homo sapiens
169 LFNG 3955
Affinity Capture-MS Homo sapiens
170 AHCYL1 10768
Co-fractionation Homo sapiens
171 HTR1E  
Affinity Capture-MS Homo sapiens
172 LMNB1 4001
Co-fractionation Homo sapiens
173 YBX1 4904
Co-fractionation Homo sapiens
174 MAD1L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 IQCB1  
Affinity Capture-MS Homo sapiens
176 TUBB4A 10382
Affinity Capture-MS Homo sapiens
177 PPP6C 5537
Affinity Capture-MS Homo sapiens
178 TNFRSF1A 7132
Reconstituted Complex Homo sapiens
179 UBC 7316
Two-hybrid Homo sapiens
180 CUL3 8452
Affinity Capture-MS Homo sapiens
181 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
182 PPP2R2A 5520
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
183 WDR37 22884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 MYO1C 4641
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 SUMO2 6613
Reconstituted Complex Homo sapiens
186 FAM187B  
Affinity Capture-MS Homo sapiens
187 BPNT1 10380
Affinity Capture-MS Homo sapiens
188 SLC25A23  
Affinity Capture-MS Homo sapiens
189 FN1 2335
Affinity Capture-MS Homo sapiens
190 STRAP 11171
Co-fractionation Homo sapiens
191 HYOU1 10525
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
192 PRMT5 10419
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
193 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
194 PCBP4 57060
Affinity Capture-MS Homo sapiens
195 RETSAT 54884
Affinity Capture-MS Homo sapiens
196 STAT1 6772
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
197 LRRC14B  
Affinity Capture-MS Homo sapiens
198 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
199 SOHLH1  
Affinity Capture-MS Homo sapiens
200 COPZ1 22818
Affinity Capture-MS Homo sapiens
201 CPLX4  
Affinity Capture-MS Homo sapiens
202 NSUN5P1  
Affinity Capture-MS Homo sapiens
203 MPZL1 9019
Affinity Capture-MS Homo sapiens
204 HSPA1A 3303
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
205 NUDC 10726
Co-fractionation Homo sapiens
206 HSPA4 3308
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
207 PSMC5 5705
Affinity Capture-MS Homo sapiens
208 PRPF40A 55660
Cross-Linking-MS (XL-MS) Homo sapiens
209 STMN1 3925
Reconstituted Complex Homo sapiens
210 P3H3 10536
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 EPB41L4B 54566
Affinity Capture-MS Homo sapiens
212 SGTA 6449
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
213 HPS6 79803
Affinity Capture-MS Homo sapiens
214 ILK 3611
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 HUS1B  
Affinity Capture-MS Homo sapiens
216 PFN2 5217
Co-fractionation Homo sapiens
217 CSDE1 7812
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
218 SCPEP1 59342
Co-fractionation Homo sapiens
219 CDKN1B 1027
Affinity Capture-Western Homo sapiens
220 KCTD15 79047
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 DLAT 1737
Co-fractionation Homo sapiens
222 NFATC2  
Affinity Capture-MS Homo sapiens
223 PABPN1 8106
Co-fractionation Homo sapiens
224 PPP2CB 5516
Cross-Linking-MS (XL-MS) Homo sapiens
225 NCAPG 64151
Co-fractionation Homo sapiens
226 KCNA5  
Affinity Capture-Western Homo sapiens
227 YIF1B 90522
Affinity Capture-MS Homo sapiens
228 STUB1 10273
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
PCA Homo sapiens
Co-fractionation Homo sapiens
Protein-peptide Homo sapiens
229 AKAP8L  
Affinity Capture-MS Homo sapiens
230 METTL14  
Affinity Capture-MS Homo sapiens
231 PSMB2 5690
Affinity Capture-MS Homo sapiens
232 RELA 5970
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
233 FBXL6  
Affinity Capture-MS Homo sapiens
234 FASN 2194
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
235 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
236 SUDS3  
Co-fractionation Homo sapiens
237 BCAS2 10286
Co-fractionation Homo sapiens
238 GRB2 2885
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
239 SLC12A4 6560
Affinity Capture-MS Homo sapiens
240 USP46 64854
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
241 FUZ 80199
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 URGCP 55665
Affinity Capture-MS Homo sapiens
243 WWOX 51741
Affinity Capture-MS Homo sapiens
244 TCERG1 10915
Affinity Capture-MS Homo sapiens
245 ZEB1  
Affinity Capture-MS Homo sapiens
246 LRRC28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
247 CDC37 11140
Affinity Capture-MS Homo sapiens
248 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
249 SKP1 6500
Co-fractionation Homo sapiens
250 IER2 9592
Affinity Capture-MS Homo sapiens
251 KCND2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 VSIG8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
253 GNA13 10672
Affinity Capture-MS Homo sapiens
254 BMPR1A 657
Affinity Capture-MS Homo sapiens
255 RUVBL2 10856
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
256 HSP90AA1 3320
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
257 PNPLA7  
Affinity Capture-MS Homo sapiens
258 RANBP2 5903
Affinity Capture-MS Homo sapiens
259 ATF1  
Affinity Capture-MS Homo sapiens
260 SSBP1 6742
Co-fractionation Homo sapiens
261 ARHGAP29 9411
Cross-Linking-MS (XL-MS) Homo sapiens
262 MAP2K2 5605
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 PSMD3 5709
Co-fractionation Homo sapiens
264 RFPL2  
Affinity Capture-MS Homo sapiens
265 CEBPA  
Proximity Label-MS Homo sapiens
266 DDX3X 1654
Affinity Capture-MS Homo sapiens
267 NOXO1  
Affinity Capture-MS Homo sapiens
268 GAPDH 2597
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
269 DRG2 1819
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 C3orf38 285237
Affinity Capture-MS Homo sapiens
271 CDK4 1019
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
272 FBXL15  
Affinity Capture-MS Homo sapiens
273 CYLD  
Affinity Capture-MS Homo sapiens
274 CLTA 1211
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 IPO7 10527
Co-fractionation Homo sapiens
276 ACO2 50
Affinity Capture-MS Homo sapiens
277 FBXL16  
Affinity Capture-MS Homo sapiens
278 PFKL 5211
Co-fractionation Homo sapiens
279 SHARPIN  
Affinity Capture-MS Homo sapiens
280 CERCAM 51148
Affinity Capture-MS Homo sapiens
281 TXNIP 10628
Affinity Capture-MS Homo sapiens
282 PRPF4 9128
Co-fractionation Homo sapiens
283 SNW1 22938
Affinity Capture-MS Homo sapiens
284 MARCH5  
Proximity Label-MS Homo sapiens
285 PSMC4 5704
Affinity Capture-MS Homo sapiens
286 SNRPA1 6627
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
287 AP5Z1 9907
Affinity Capture-MS Homo sapiens
288 PHF8  
Affinity Capture-MS Homo sapiens
289 GAPVD1 26130
Co-fractionation Homo sapiens
290 PRAMEF12  
Affinity Capture-MS Homo sapiens
291 GALNT9  
Affinity Capture-MS Homo sapiens
292 HERC5 51191
Affinity Capture-Western Homo sapiens
293 DERL1 79139
Affinity Capture-MS Homo sapiens
294 SLC25A6 293
Affinity Capture-MS Homo sapiens
295 CDCA5  
Affinity Capture-MS Homo sapiens
296 PTPRF 5792
Two-hybrid Homo sapiens
297 KIF16B 55614
Affinity Capture-MS Homo sapiens
298 AMT  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
299 ARMC5 79798
Affinity Capture-MS Homo sapiens
300 HBB 3043
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 TLE2  
Affinity Capture-MS Homo sapiens
302 KIF23 9493
Co-fractionation Homo sapiens
303 NCBP1 4686
Co-fractionation Homo sapiens
304 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
305 VARS 7407
Affinity Capture-MS Homo sapiens
306 CDK3 1018
Affinity Capture-MS Homo sapiens
307 HMCES  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
308 HSPA6 3310
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
309 AIPL1  
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
310 SNX1 6642
Affinity Capture-MS Homo sapiens
311 TUBB3 10381
Affinity Capture-MS Homo sapiens
312 GJA1 2697
Affinity Capture-MS Homo sapiens
313 CYP8B1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
314 CTBP2 1488
Affinity Capture-MS Homo sapiens
315 DOK3 79930
Affinity Capture-MS Homo sapiens
316 TARDBP 23435
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
317 RPA2 6118
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
318 MCF2  
Affinity Capture-Western Homo sapiens
319 NACA 4666
Co-fractionation Homo sapiens
320 QKI 9444
Affinity Capture-MS Homo sapiens
321 UCHL1 7345
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
322 PACSIN2 11252
Affinity Capture-MS Homo sapiens
323 SPEN 23013
Affinity Capture-MS Homo sapiens
324 DTNA  
Affinity Capture-MS Homo sapiens
325 TRIM33 51592
Affinity Capture-MS Homo sapiens
326 HSP90AB1 3326
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
327 ROCK2 9475
Co-fractionation Homo sapiens
328 EIF4A1 1973
Affinity Capture-MS Homo sapiens
329 VAMP2 6844
Co-fractionation Homo sapiens
330 CAND1 55832
Affinity Capture-MS Homo sapiens
331 SRSF2 6427
Co-fractionation Homo sapiens
332 COPA 1314
Affinity Capture-MS Homo sapiens
333 SETMAR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
334 RPS3 6188
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
335 DNAJB6 10049
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
336 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
337 OPN1SW  
Affinity Capture-MS Homo sapiens
338 VANGL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
339 SEC23IP 11196
Co-fractionation Homo sapiens
340 RNPS1 10921
Co-fractionation Homo sapiens
341 B3GNT2 10678
Affinity Capture-MS Homo sapiens
342 HSPA2 3306
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
343 POLE4  
Affinity Capture-MS Homo sapiens
344 CDK11B 984
Affinity Capture-MS Homo sapiens
345 ABHD15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
346 DPH2 1802
Affinity Capture-MS Homo sapiens
347 COPS6 10980
Affinity Capture-MS Homo sapiens
348 CSRP1 1465
Affinity Capture-MS Homo sapiens
349 lqf  
Affinity Capture-Western Drosophila melanogaster
350 HEY1  
Affinity Capture-MS Homo sapiens
351 FBXO17 115290
Affinity Capture-MS Homo sapiens
352 MRPS23 51649
Co-fractionation Homo sapiens
353 TBC1D23 55773
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 SRRM2 23524
Affinity Capture-MS Homo sapiens
355 MLST8 64223
Affinity Capture-MS Homo sapiens
356 RECQL4  
Affinity Capture-MS Homo sapiens
357 CNN2 1265
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
358 SF3B4 10262
Co-fractionation Homo sapiens
359 C6orf106  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
360 STIP1 10963
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
361 NR4A1  
Affinity Capture-MS Homo sapiens
362 CPLX1 10815
Affinity Capture-MS Homo sapiens
363 ELP4  
Affinity Capture-MS Homo sapiens
364 DNAJC7 7266
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
365 VCAM1 7412
Affinity Capture-MS Homo sapiens
366 FOXD4  
Affinity Capture-MS Homo sapiens
367 GXYLT2  
Affinity Capture-MS Homo sapiens
368 TTLL5  
Affinity Capture-MS Homo sapiens
369 CUL1 8454
Affinity Capture-MS Homo sapiens
370 POLR2M  
Affinity Capture-MS Homo sapiens
371 LRRC36  
Affinity Capture-MS Homo sapiens
372 KNSTRN  
Affinity Capture-MS Homo sapiens
373 NPAS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
374 PLS3 5358
Co-fractionation Homo sapiens
375 RYBP  
Co-fractionation Homo sapiens
376 IQCF2  
Affinity Capture-MS Homo sapiens
377 ATAD3A 55210
Affinity Capture-MS Homo sapiens
378 EEFSEC 60678
Affinity Capture-MS Homo sapiens
379 AGBL5  
Affinity Capture-MS Homo sapiens
380 LMAN1 3998
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
381 PFN1 5216
Co-fractionation Homo sapiens
382 IL32  
Two-hybrid Homo sapiens
383 PFKM 5213
Affinity Capture-MS Homo sapiens
384 VRK3 51231
Affinity Capture-MS Homo sapiens
385 CYP2W1  
Affinity Capture-MS Homo sapiens
386 SLC25A10 1468
Affinity Capture-MS Homo sapiens
387 DNAJB8 165721
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
388 PPP5C 5536
Affinity Capture-MS Homo sapiens
389 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
390 USP10 9100
Affinity Capture-MS Homo sapiens
391 RBX1 9978
Affinity Capture-MS Homo sapiens
392 CLEC14A  
Affinity Capture-MS Homo sapiens
393 TSFM 10102
Co-fractionation Homo sapiens
394 CDKN1A  
Affinity Capture-MS Homo sapiens
395 KLC1 3831
Affinity Capture-MS Homo sapiens
396 SLC9A5  
Affinity Capture-MS Homo sapiens
397 NR1H3  
Affinity Capture-MS Homo sapiens
398 SNRPA 6626
Co-fractionation Homo sapiens
399 ZBTB18  
Affinity Capture-MS Homo sapiens
400 TRMT12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
401 TBCE 6905
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
402 PABPC4 8761
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
403 PSMD14 10213
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
404 CBL 867
Affinity Capture-MS Homo sapiens
405 EPRS 2058
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
406 VRK1 7443
Affinity Capture-MS Homo sapiens
407 PLD2 5338
Affinity Capture-MS Homo sapiens
408 TUBB2B 347733
Co-fractionation Homo sapiens
409 FARSB 10056
Affinity Capture-MS Homo sapiens
410 EP300 2033
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
411 PSMA1 5682
Affinity Capture-MS Homo sapiens
412 SNRPD1 6632
Co-fractionation Homo sapiens
413 CSTF3 1479
Affinity Capture-MS Homo sapiens
414 HAO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
415 KLC2 64837
Affinity Capture-MS Homo sapiens
416 C20orf195  
Affinity Capture-MS Homo sapiens
417 CTNNB1 1499
Affinity Capture-MS Homo sapiens
418 HEMGN  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
419 CD207  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
420 PRRC1 133619
Affinity Capture-MS Homo sapiens
421 TTC9C 283237
Affinity Capture-MS Homo sapiens
422 Bag2  
Affinity Capture-MS Mus musculus
423 SLC25A42  
Affinity Capture-MS Homo sapiens
424 PSMA7 5688
Co-fractionation Homo sapiens
425 IL17RC 84818
Affinity Capture-MS Homo sapiens
426 MAGOH 4116
Affinity Capture-MS Homo sapiens
427 RPLP0 6175
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
428 HNRNPAB 3182
Co-fractionation Homo sapiens
429 AGPS 8540
Affinity Capture-MS Homo sapiens
430 Ksr1  
Affinity Capture-MS Mus musculus
431 RBSN 64145
Affinity Capture-Western Homo sapiens
432 LRRK2 120892
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
433 TCP1 6950
Affinity Capture-MS Homo sapiens
434 CARS 833
Co-fractionation Homo sapiens
435 TCAP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
436 EIF4B 1975
Affinity Capture-MS Homo sapiens
437 FBXL4 26235
Affinity Capture-MS Homo sapiens
438 C3orf20  
Affinity Capture-MS Homo sapiens
439 MYH7B  
Affinity Capture-MS Homo sapiens
440 HNRNPD 3184
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
441 KIF1B 23095
Affinity Capture-MS Homo sapiens
442 CAMKMT  
Affinity Capture-MS Homo sapiens
443 PSMA3 5684
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
444 CYP3A4  
Affinity Capture-MS Homo sapiens
445 RNF34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
446 FRMD8P1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
447 PANK2 80025
Affinity Capture-MS Homo sapiens
448 PFAS 5198
Affinity Capture-MS Homo sapiens
449 KCND3 3752
Affinity Capture-Western Homo sapiens
450 ARRB1 408
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
451 MAPK15  
Affinity Capture-MS Homo sapiens
452 USP15 9958
Co-fractionation Homo sapiens
453 RC3H2  
Affinity Capture-MS Homo sapiens
454 SLC25A3 5250
Affinity Capture-MS Homo sapiens
455 IKZF3  
Affinity Capture-MS Homo sapiens
456 HNRNPL 3191
Co-fractionation Homo sapiens
457 PPA1 5464
Co-fractionation Homo sapiens
458 UBE2L3 7332
Cross-Linking-MS (XL-MS) Homo sapiens
459 PTH2R  
Affinity Capture-MS Homo sapiens
460 UBE2L6 9246
Affinity Capture-MS Homo sapiens
461 SYNPO2  
Affinity Capture-Western Homo sapiens
462 TJP1 7082
Co-fractionation Homo sapiens
463 RPL3 6122
Affinity Capture-MS Homo sapiens
464 BTF3 689
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
465 EGFR 1956
PCA Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
466 PACSIN3 29763
Affinity Capture-MS Homo sapiens
467 FUS 2521
Affinity Capture-MS Homo sapiens
468 HNRNPF 3185
Co-fractionation Homo sapiens
469 IKZF1  
Affinity Capture-MS Homo sapiens
470 RIPK4  
Affinity Capture-MS Homo sapiens
471 GMDS 2762
Proximity Label-MS Homo sapiens
472 HIST3H3 8290
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
473 RPN1 6184
Affinity Capture-MS Homo sapiens
474 C21orf59 56683
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
475 SSH3 54961
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
476 SCYL2 55681
Affinity Capture-MS Homo sapiens
477 RPS27 6232
Affinity Capture-MS Homo sapiens
478 CDK2 1017
Affinity Capture-MS Homo sapiens
479 CEP250 11190
Affinity Capture-MS Homo sapiens
480 Tgfbr1 21812
Affinity Capture-MS Mus musculus
481 YARS 8565
Co-fractionation Homo sapiens
482 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
483 BAG1 573
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Luminescence Homo sapiens
484 ALDH3B2  
Affinity Capture-MS Homo sapiens
485 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
486 ATP5B 506
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
487 EDRF1  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
488 CRAMP1L 57585
Cross-Linking-MS (XL-MS) Homo sapiens
489 CDK20  
Affinity Capture-MS Homo sapiens
490 DDB1 1642
Co-fractionation Homo sapiens
491 DNM1 1759
Co-fractionation Homo sapiens
492 DDRGK1 65992
Affinity Capture-MS Homo sapiens
493 KCNV1  
Affinity Capture-MS Homo sapiens
494 CDK10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
495 MYB  
Affinity Capture-Western Homo sapiens
496 ENTHD2  
Affinity Capture-MS Homo sapiens
497 PIK3R6  
Affinity Capture-MS Homo sapiens
498 CYFIP1 23191
Co-fractionation Homo sapiens
499 SSMEM1  
Affinity Capture-MS Homo sapiens
500 PIGQ  
Affinity Capture-MS Homo sapiens
501 PHGDH 26227
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
502 ZC3H13 23091
Co-fractionation Homo sapiens
503 Bax 12028
Affinity Capture-Western Mus musculus
504 LARS 51520
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
505 KIAA0100  
Affinity Capture-MS Homo sapiens
506 DHDH  
Affinity Capture-MS Homo sapiens
507 NAPRT 93100
Co-fractionation Homo sapiens
508 TRIM38 10475
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
509 SFPQ 6421
Co-fractionation Homo sapiens
510 EIF3F 8665
Affinity Capture-MS Homo sapiens
511 GOT2 2806
Reconstituted Complex Homo sapiens
512 KLHL36  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
513 SPOP  
Affinity Capture-MS Homo sapiens
514 PRRC2A 7916
Affinity Capture-MS Homo sapiens
515 CCIN  
Affinity Capture-MS Homo sapiens
516 ILF3 3609
Co-fractionation Homo sapiens
517 HMGB1 3146
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
518 SLK 9748
Affinity Capture-MS Homo sapiens
519 FOLR1 2348
Affinity Capture-MS Homo sapiens
520 EPB42 2038
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
521 RFWD2  
Affinity Capture-MS Homo sapiens
522 SH2D3A  
Affinity Capture-MS Homo sapiens
523 HDAC6 10013
Affinity Capture-MS Homo sapiens
524 MCL1 4170
Affinity Capture-Western Homo sapiens
525 TFDP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
526 ATXN2 6311
Co-fractionation Homo sapiens
527 KCNC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
528 HLTF  
Two-hybrid Homo sapiens
529 PRKACA 5566
Co-fractionation Homo sapiens
530 CCDC117  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
531 PNPLA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
532 ASS1 445
Affinity Capture-MS Homo sapiens
533 MLH1 4292
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
534 FAM83F 113828
Affinity Capture-MS Homo sapiens
535 OTUB1 55611
Affinity Capture-MS Homo sapiens
536 AGO2 27161
Co-fractionation Homo sapiens
537 FKBP5 2289
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
538 MAP2K1 5604
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
539 YTHDF3  
Affinity Capture-MS Homo sapiens
540 POU2F1 5451
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
541 MAPK6  
Affinity Capture-MS Homo sapiens
542 ESR1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
543 C10orf32  
Affinity Capture-MS Homo sapiens
544 CDV3 55573
Affinity Capture-MS Homo sapiens
545 QRICH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
546 GMPPA 29926
Affinity Capture-MS Homo sapiens
547 ERRFI1 54206
Affinity Capture-MS Homo sapiens
548 DNAJB4 11080
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
549 POLR3D  
Affinity Capture-MS Homo sapiens
550 STK35  
Affinity Capture-MS Homo sapiens
551 ERH 2079
Two-hybrid Homo sapiens
552 ALDH3B1 221
Affinity Capture-MS Homo sapiens
553 ATP10A 57194
Affinity Capture-MS Homo sapiens
554 Ranbp2  
Affinity Capture-MS Mus musculus
555 C1QBP 708
Affinity Capture-MS Homo sapiens
556 TM4SF1 4071
Two-hybrid Homo sapiens
557 HNRNPC 3183
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
558 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
559 CYCS 54205
Reconstituted Complex Homo sapiens
560 MYC  
Affinity Capture-MS Homo sapiens
561 PTRF 284119
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
562 RBBP4 5928
Co-fractionation Homo sapiens
563 JAK2 3717
Affinity Capture-Western Homo sapiens
564 PRMT1 3276
Affinity Capture-MS Homo sapiens
565 CCT4 10575
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
566 KCNQ4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
567 SEC31A 22872
Co-fractionation Homo sapiens
568 CUL4A 8451
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
569 ATP5A1 498
Affinity Capture-MS Homo sapiens
570 MVP 9961
Affinity Capture-MS Homo sapiens
571 MCM7 4176
Affinity Capture-MS Homo sapiens
572 NLRP12  
Affinity Capture-Western Homo sapiens
573 LGALS12  
Affinity Capture-MS Homo sapiens
574 ACSM2B  
Affinity Capture-MS Homo sapiens
575 DSP 1832
Co-fractionation Homo sapiens
576 GMNN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
577 EML4 27436
Affinity Capture-MS Homo sapiens
578 USP43  
Affinity Capture-MS Homo sapiens
579 RAB1A 5861
Co-fractionation Homo sapiens
580 EEF1G 1937
Co-fractionation Homo sapiens
581 KIAA1107  
Affinity Capture-MS Homo sapiens
582 SAMM50 25813
Co-fractionation Homo sapiens
583 NAPA 8775
Co-fractionation Homo sapiens
584 HTN3  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
585 TRIM7  
Affinity Capture-MS Homo sapiens
586 MME 4311
Affinity Capture-MS Homo sapiens
587 CD4 920
Affinity Capture-MS Homo sapiens
588 ANAPC5 51433
Affinity Capture-MS Homo sapiens
589 ZNF608  
Affinity Capture-MS Homo sapiens
590 PAK2 5062
Co-fractionation Homo sapiens
591 EPS15 2060
Affinity Capture-MS Homo sapiens
592 NMI  
Two-hybrid Homo sapiens
593 SEPT12  
Affinity Capture-MS Homo sapiens
594 GK2 2712
Affinity Capture-MS Homo sapiens
595 IL16  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
596 HNRNPR 10236
Co-fractionation Homo sapiens
597 PSMD10 5716
Co-fractionation Homo sapiens
598 RPS6KB2  
Affinity Capture-MS Homo sapiens
599 PELO 53918
Affinity Capture-MS Homo sapiens
600 ZNF618  
Affinity Capture-MS Homo sapiens
601 HSF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
602 LRPPRC 10128
Affinity Capture-MS Homo sapiens
603 CAPZB 832
Reconstituted Complex Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
604 RUVBL1 8607
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
605 ERLIN2 11160
Affinity Capture-MS Homo sapiens
606 DENND2D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
607 MCM2 4171
Affinity Capture-MS Homo sapiens
608 IARS 3376
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
609 D2HGDH 728294
Affinity Capture-MS Homo sapiens
610 ZNF638 27332
Co-fractionation Homo sapiens
611 RBM14 10432
Affinity Capture-MS Homo sapiens
612 SPAG9 9043
Co-fractionation Homo sapiens
613 ZNF215  
Affinity Capture-MS Homo sapiens
614 FLNA 2316
Co-fractionation Homo sapiens
615 IQGAP1 8826
Co-fractionation Homo sapiens
616 PSME1 5720
Co-fractionation Homo sapiens
617 HIST2H3PS2 440686
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
618 SF3A2 8175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
619 HCFC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
620 ASNS 440
Affinity Capture-MS Homo sapiens
621 IKBKE 9641
Affinity Capture-MS Homo sapiens
622 PPP2CA 5515
Affinity Capture-MS Homo sapiens
623 GNA15 2769
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
624 ITGA4 3676
Affinity Capture-MS Homo sapiens
625 CKAP5 9793
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
626 RPL18 6141
Cross-Linking-MS (XL-MS) Homo sapiens
627 TRIM16L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
628 CLTC 1213
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
629 TUBA1A 7846
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
630 GPN1  
Affinity Capture-MS Homo sapiens
631 MAVS 57506
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
632 TFCP2 7024
Affinity Capture-MS Homo sapiens
633 SERBP1 26135
Affinity Capture-MS Homo sapiens
634 CFAP52  
Affinity Capture-MS Homo sapiens
635 YAF2  
Affinity Capture-MS Homo sapiens
636 C19orf45  
Affinity Capture-MS Homo sapiens
637 RNF207  
Affinity Capture-Western Homo sapiens
638 ALOXE3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
639 HSPA8 3312
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
640 LCMT2 9836
Affinity Capture-MS Homo sapiens
641 COL2A1 1280
Cross-Linking-MS (XL-MS) Homo sapiens
642 INSIG2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
643 CCND1 595
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
644 HSPBP1 23640
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
645 C2orf27B  
Affinity Capture-MS Homo sapiens
646 C9orf171  
Affinity Capture-MS Homo sapiens
647 ACTL6B  
Affinity Capture-MS Homo sapiens
648 RGS2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
649 CNOT2  
Affinity Capture-MS Homo sapiens
650 ASNA1 439
Co-fractionation Homo sapiens
651 IRAK1  
Affinity Capture-MS Homo sapiens
652 SRRM1 10250
Co-fractionation Homo sapiens
653 CUL4B 8450
Affinity Capture-MS Homo sapiens
654 PARK2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
655 IGF1R 3480
Affinity Capture-MS Homo sapiens
656 COPE 11316
Affinity Capture-MS Homo sapiens
657 B4GALT2  
Affinity Capture-MS Homo sapiens
658 ACACA 31
Co-fractionation Homo sapiens
659 TTC1 7265
Reconstituted Complex Homo sapiens
660 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
661 NMNAT3 349565
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
662 USP36  
Affinity Capture-MS Homo sapiens
663 SRRT 51593
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
664 POC1A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
665 EPS8L2 64787