Gene description for MXRA7
Gene name matrix-remodelling associated 7
Gene symbol MXRA7
Other names/aliases PS1TP1
TMAP1
Species Homo sapiens
 Database cross references - MXRA7
ExoCarta ExoCarta_439921
Vesiclepedia VP_439921
Entrez Gene 439921
HGNC 7541
UniProt P84157  
 MXRA7 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for MXRA7
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    membrane GO:0016020 IEA
    collagen-containing extracellular matrix GO:0062023 HDA
 Experiment description of studies that identified MXRA7 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for MXRA7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 REEP5 7905
Proximity Label-MS Homo sapiens
2 HSD17B11 51170
Proximity Label-MS Homo sapiens
3 RAB35 11021
Proximity Label-MS Homo sapiens
4 CYB5B 80777
Co-fractionation Homo sapiens
5 RPN2 6185
Proximity Label-MS Homo sapiens
6 GRIN3B  
Affinity Capture-MS Homo sapiens
7 METTL7A 25840
Proximity Label-MS Homo sapiens
8 RAB9A 9367
Proximity Label-MS Homo sapiens
9 LRRC59 55379
Proximity Label-MS Homo sapiens
10 LMNB1 4001
Proximity Label-MS Homo sapiens
11 LMAN1 3998
Proximity Label-MS Homo sapiens
12 NUP155 9631
Proximity Label-MS Homo sapiens
13 KIAA1715 80856
Proximity Label-MS Homo sapiens
14 RAB5A 5868
Proximity Label-MS Homo sapiens
15 PANX1 24145
Proximity Label-MS Homo sapiens
16 BCAP31 10134
Proximity Label-MS Homo sapiens
17 HSD3B7 80270
Proximity Label-MS Homo sapiens
18 STIM1 6786
Proximity Label-MS Homo sapiens
19 SEC63 11231
Proximity Label-MS Homo sapiens
20 EMD 2010
Proximity Label-MS Homo sapiens
21 DNAJC25 548645
Proximity Label-MS Homo sapiens
22 GUCY1B3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
24 STX4 6810
Proximity Label-MS Homo sapiens
25 MAP2K1 5604
Affinity Capture-MS Homo sapiens
26 GUCY2D  
Affinity Capture-MS Homo sapiens
27 NXF1 10482
Affinity Capture-RNA Homo sapiens
28 RAB4A 5867
Proximity Label-MS Homo sapiens
29 ERGIC2 51290
Proximity Label-MS Homo sapiens
30 B3GAT1  
Proximity Label-MS Homo sapiens
31 MOV10 4343
Affinity Capture-RNA Homo sapiens
32 CYB5A 1528
Co-fractionation Homo sapiens
33 SEC62 7095
Proximity Label-MS Homo sapiens
34 ATP2A1 487
Proximity Label-MS Homo sapiens
35 PTPN1 5770
Proximity Label-MS Homo sapiens
36 RAB7A 7879
Proximity Label-MS Homo sapiens
37 RAB11A 8766
Proximity Label-MS Homo sapiens
38 RAB3B 5865
Proximity Label-MS Homo sapiens
39 PCDHA12  
Affinity Capture-MS Homo sapiens
40 RPN1 6184
Proximity Label-MS Homo sapiens
41 DNAJC1 64215
Proximity Label-MS Homo sapiens
42 FKBP8 23770
Proximity Label-MS Homo sapiens
43 SSR1 6745
Proximity Label-MS Homo sapiens
44 CKAP4 10970
Proximity Label-MS Homo sapiens
45 ELOVL5 60481
Proximity Label-MS Homo sapiens
46 GJD3  
Proximity Label-MS Homo sapiens
47 SEC61B 10952
Proximity Label-MS Homo sapiens
48 DERL1 79139
Proximity Label-MS Homo sapiens
49 CCDC47 57003
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which MXRA7 is involved
No pathways found





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