Gene description for PC
Gene name	pyruvate carboxylase
Gene symbol	PC
Other names/aliases	PCB
Species	Homo sapiens
Database cross references - PC
ExoCarta	ExoCarta_5091
Entrez Gene	5091
HGNC	8636
MIM	608786
UniProt	P11498
PC identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for PC

Molecular Function     pyruvate carboxylase activity GO:0004736 TAS     protein binding GO:0005515 IPI     biotin binding GO:0009374 IEA     biotin carboxylase activity GO:0004075 IEA     ATP binding GO:0005524 IEA     metal ion binding GO:0046872 IEA     DNA binding GO:0003677 IEA Biological Process     negative regulation of gene expression GO:0010629 IMP     biotin metabolic process GO:0006768 TAS     positive regulation by host of viral release from host cell GO:0044791 IMP     water-soluble vitamin metabolic process GO:0006767 TAS     gluconeogenesis GO:0006094 TAS     viral RNA genome packaging GO:0019074 IMP     small molecule metabolic process GO:0044281 TAS     oxaloacetate metabolic process GO:0006107 IEA     carbohydrate metabolic process GO:0005975 TAS     lipid metabolic process GO:0006629 IEA     vitamin metabolic process GO:0006766 TAS     positive regulation by host of viral process GO:0044794 IMP     pyruvate metabolic process GO:0006090 IEA     glucose metabolic process GO:0006006 TAS Subcellular Localization     mitochondrion GO:0005739 IDA     mitochondrial matrix GO:0005759 TAS     cytosol GO:0005829 TAS     mitochondrial inner membrane GO:0005743 IEA     cytoplasm GO:0005737 IDA