Gene description for ALDH3A2
Gene name aldehyde dehydrogenase 3 family, member A2
Gene symbol ALDH3A2
Other names/aliases ALDH10
FALDH
SLS
Species Homo sapiens
 Database cross references - ALDH3A2
ExoCarta ExoCarta_224
Entrez Gene 224
HGNC 403
MIM 609523
UniProt P51648  
 ALDH3A2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ALDH3A2
Molecular Function
    aldehyde dehydrogenase (NAD) activity GO:0004029 IMP
    medium-chain-aldehyde dehydrogenase activity GO:0052814 IDA
    long-chain-alcohol oxidase activity GO:0046577 IDA
    3-chloroallyl aldehyde dehydrogenase activity GO:0004028 IBA
    aldehyde dehydrogenase [NAD(P)+] activity GO:0004030 IEA
    long-chain-aldehyde dehydrogenase activity GO:0050061 IDA
Biological Process
    sesquiterpenoid metabolic process GO:0006714 IDA
    peripheral nervous system development GO:0007422 IMP
    cellular aldehyde metabolic process GO:0006081 NAS
    central nervous system development GO:0007417 IMP
    epidermis development GO:0008544 IMP
    oxidation-reduction process GO:0055114 IDA
    phytol metabolic process GO:0033306 IMP
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IEA
    integral component of membrane GO:0016021 IEA
    peroxisome GO:0005777 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    extracellular exosome GO:0070062 IDA
    mitochondrial inner membrane GO:0005743 IEA
 Experiment description of studies that identified ALDH3A2 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ALDH3A2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ALDH3A2 is involved
No pathways found





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