Gene description for MARVELD2
Gene name MARVEL domain containing 2
Gene symbol MARVELD2
Other names/aliases DFNB49
MARVD2
MRVLDC2
Tric
Species Homo sapiens
 Database cross references - MARVELD2
ExoCarta ExoCarta_153562
Entrez Gene 153562
HGNC 26401
MIM 610572
UniProt Q8N4S9  
 MARVELD2 identified in exosomes derived from the following tissue/cell type
Breast cancer cells 19415654    
 Gene ontology annotations for MARVELD2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    cell-cell junction organization GO:0045216 IMP
    bicellular tight junction assembly GO:0070830 IMP
    sensory perception of sound GO:0007605 IMP
    establishment of endothelial barrier GO:0061028 IMP
Subcellular Localization
    bicellular tight junction GO:0005923 IDA
    apical plasma membrane GO:0016324 IDA
    basolateral plasma membrane GO:0016323 IDA
    cytoplasmic vesicle GO:0031410 IDA
    Schmidt-Lanterman incisure GO:0043220 IEA
    cytoplasm GO:0005737 IDA
    integral component of membrane GO:0016021 IEA
    paranodal junction GO:0033010 IEA
 Experiment description of studies that identified MARVELD2 in exosomes
1
Experiment ID 65
ISEV standards
EV Biophysical techniques
HSP60|HSP27|GAPDH
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19415654    
Organism Homo sapiens
Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
Authors Staubach S, Razawi H, Hanisch FG.
Journal name PROTEOMICS
Publication year 2009
Sample Breast cancer cells
Sample name MCF-7
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
 Protein-protein interactions for MARVELD2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which MARVELD2 is involved
No pathways found





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