Gene description for PVRL2
Gene name poliovirus receptor-related 2 (herpesvirus entry mediator B)
Gene symbol PVRL2
Other names/aliases CD112
HVEB
PRR2
PVRR2
Species Homo sapiens
 Database cross references - PVRL2
ExoCarta ExoCarta_5819
Vesiclepedia VP_5819
Entrez Gene 5819
HGNC 9707
MIM 600798
UniProt Q92692  
 PVRL2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 25844599    
 Gene ontology annotations for PVRL2
Molecular Function
    virus receptor activity GO:0001618 IEA
    protein binding GO:0005515 IPI
    coreceptor activity GO:0015026 TAS
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 IPI
    receptor ligand activity GO:0048018 IDA
    cell adhesion molecule binding GO:0050839 IBA
    cell adhesion molecule binding GO:0050839 IPI
Biological Process
    acrosome assembly GO:0001675 IBA
    positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 IBA
    positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860 IMP
    positive regulation of immunoglobulin mediated immune response GO:0002891 IBA
    positive regulation of immunoglobulin mediated immune response GO:0002891 IMP
    cytoskeleton organization GO:0007010 IEA
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IBA
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IDA
    signal transduction GO:0007165 IEA
    spermatid development GO:0007286 ISS
    spermatid nucleus differentiation GO:0007289 IEA
    fertilization GO:0009566 IEA
    fusion of virus membrane with host plasma membrane GO:0019064 IDA
    sperm mitochondrion organization GO:0030382 IEA
    positive regulation of mast cell activation GO:0033005 IBA
    positive regulation of mast cell activation GO:0033005 IMP
    natural killer cell mediated cytotoxicity GO:0042267 IDA
    susceptibility to natural killer cell mediated cytotoxicity GO:0042271 IMP
    adhesion of symbiont to host GO:0044406 IDA
    cilium organization GO:0044782 IEA
    negative regulation of natural killer cell mediated cytotoxicity GO:0045953 IDA
    positive regulation of natural killer cell mediated cytotoxicity GO:0045954 IMP
    regulation of viral entry into host cell GO:0046596 IDA
    symbiont entry into host cell GO:0046718 IEA
    coreceptor-mediated virion attachment to host cell GO:0046814 IBA
    coreceptor-mediated virion attachment to host cell GO:0046814 IDA
    positive regulation of T cell receptor signaling pathway GO:0050862 IBA
    positive regulation of T cell receptor signaling pathway GO:0050862 IDA
    establishment of localization in cell GO:0051649 IEA
    establishment of mitochondrion localization GO:0051654 IEA
    susceptibility to T cell mediated cytotoxicity GO:0060370 IDA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IC
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    cell-cell junction GO:0005911 IDA
    zonula adherens GO:0005915 ISS
    focal adhesion GO:0005925 HDA
    cell surface GO:0009986 IDA
    membrane GO:0016020 IDA
    apical junction complex GO:0043296 IBA
    cell-cell contact zone GO:0044291 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified PVRL2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
8
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for PVRL2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIAH1  
Two-hybrid Homo sapiens
2 LPPR4  
Affinity Capture-MS Homo sapiens
3 TMEM30B 161291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 GJD3  
Proximity Label-MS Homo sapiens
5 OCLN 100506658
Proximity Label-MS Homo sapiens
6 METTL7A 25840
Proximity Label-MS Homo sapiens
7 LAMP3  
Proximity Label-MS Homo sapiens
8 LCE2C  
Two-hybrid Homo sapiens
9 AKAP12 9590
Affinity Capture-MS Homo sapiens
10 HPN  
Affinity Capture-MS Homo sapiens
11 PARD3 56288
Proximity Label-MS Homo sapiens
12 MDFI  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
13 KRTAP5-9  
Two-hybrid Homo sapiens
14 STX4 6810
Proximity Label-MS Homo sapiens
15 APOD 347
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 TOMM22 56993
Co-fractionation Homo sapiens
17 APEX1 328
Affinity Capture-RNA Homo sapiens
18 BTBD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 B3GAT1  
Proximity Label-MS Homo sapiens
20 MLLT4 4301
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
21 TBC1D22A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ST14 6768
Affinity Capture-MS Homo sapiens
23 RGS20 8601
Two-hybrid Homo sapiens
24 NR4A3  
Two-hybrid Homo sapiens
25 RAB35 11021
Proximity Label-MS Homo sapiens
26 TMEM106A  
Affinity Capture-MS Homo sapiens
27 EBAG9 9166
Proximity Label-MS Homo sapiens
28 USP53 54532
Two-hybrid Homo sapiens
29 MARCKS 4082
Proximity Label-MS Homo sapiens
30 LAMTOR1 55004
Proximity Label-MS Homo sapiens
31 ALOXE3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 PRPH2 5961
Affinity Capture-MS Homo sapiens
33 DUS2 54920
Two-hybrid Homo sapiens
34 GJA1 2697
Proximity Label-MS Homo sapiens
35 CEACAM21  
Affinity Capture-MS Homo sapiens
36 CXADR 1525
Proximity Label-MS Homo sapiens
37 SBSN 374897
Affinity Capture-MS Homo sapiens
38 KRTAP10-1  
Two-hybrid Homo sapiens
39 LYN 4067
Proximity Label-MS Homo sapiens
40 MCAM 4162
Proximity Label-MS Homo sapiens
41 RAB4A 5867
Proximity Label-MS Homo sapiens
42 DNAJC5 80331
Proximity Label-MS Homo sapiens
43 CDH1 999
Proximity Label-MS Homo sapiens
44 DIRAS3  
Proximity Label-MS Homo sapiens
45 CYSRT1 375791
Two-hybrid Homo sapiens
46 KRTAP10-8  
Two-hybrid Homo sapiens
47 DTX2 113878
Proximity Label-MS Homo sapiens
48 BRICD5  
Affinity Capture-MS Homo sapiens
49 MEOX2  
Two-hybrid Homo sapiens
50 P4HB 5034
Two-hybrid Homo sapiens
51 LYRM4 57128
Two-hybrid Homo sapiens
52 SERPINA3 12
Affinity Capture-MS Homo sapiens
53 ELOVL5 60481
Proximity Label-MS Homo sapiens
54 CTDSPL 10217
Proximity Label-MS Homo sapiens
55 TMPRSS13  
Affinity Capture-MS Homo sapiens
56 KRTAP10-7  
Two-hybrid Homo sapiens
57 NOTCH2NL 388677
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
58 PICK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
59 LCE5A  
Two-hybrid Homo sapiens
60 KRTAP1-3  
Two-hybrid Homo sapiens
61 PANK2 80025
Affinity Capture-MS Homo sapiens
62 CANX 821
Affinity Capture-MS Homo sapiens
63 RAB5A 5868
Proximity Label-MS Homo sapiens
64 TMPRSS11B 132724
Affinity Capture-MS Homo sapiens
65 TNFSF8  
Affinity Capture-MS Homo sapiens
66 EPB41L4A 64097
Proximity Label-MS Homo sapiens
67 LAMP1 3916
Proximity Label-MS Homo sapiens
68 CLEC4A  
Affinity Capture-MS Homo sapiens
69 ARF6 382
Proximity Label-MS Homo sapiens
70 KRTAP10-3  
Two-hybrid Homo sapiens
71 HOXA1 3198
Two-hybrid Homo sapiens
72 CD226 10666
Reconstituted Complex Homo sapiens
73 MAPK6  
Two-hybrid Homo sapiens
74 ATP5J2 9551
Two-hybrid Homo sapiens
75 RAB9A 9367
Proximity Label-MS Homo sapiens
76 FUT9  
Affinity Capture-MS Homo sapiens
77 PVR 5817
Affinity Capture-MS Homo sapiens
78 RHOB 388
Proximity Label-MS Homo sapiens
79 RAB5C 5878
Proximity Label-MS Homo sapiens
80 FLOT1 10211
Proximity Label-MS Homo sapiens
81 KRTAP10-5  
Two-hybrid Homo sapiens
82 LCE1C  
Two-hybrid Homo sapiens
83 ST3GAL5  
Affinity Capture-MS Homo sapiens
84 HVCN1 84329
Affinity Capture-MS Homo sapiens
85 PVRL2 5819
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
86 SERPINA12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 SPAG6  
Affinity Capture-MS Homo sapiens
88 RSPH14  
Affinity Capture-MS Homo sapiens
89 NBPF19  
Two-hybrid Homo sapiens
90 RYK 6259
Affinity Capture-MS Homo sapiens
91 KRTAP1-1  
Two-hybrid Homo sapiens
92 C11orf52 91894
Proximity Label-MS Homo sapiens
93 LCE2B  
Two-hybrid Homo sapiens
94 TCF4  
Two-hybrid Homo sapiens
95 RAB2A 5862
Proximity Label-MS Homo sapiens
96 KRTAP12-2  
Two-hybrid Homo sapiens
97 RAB7A 7879
Proximity Label-MS Homo sapiens
98 RAB11A 8766
Proximity Label-MS Homo sapiens
99 EPHA2 1969
Proximity Label-MS Homo sapiens
100 CST11  
Affinity Capture-MS Homo sapiens
101 SYPL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 KRAS 3845
Proximity Label-MS Homo sapiens
103 RARS 5917
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 CAV1 857
Proximity Label-MS Homo sapiens
105 PVRL3 25945
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here