Gene description for CKAP4
Gene name cytoskeleton-associated protein 4
Gene symbol CKAP4
Other names/aliases CLIMP-63
ERGIC-63
p63
Species Homo sapiens
 Database cross references - CKAP4
ExoCarta ExoCarta_10970
Vesiclepedia VP_10970
Entrez Gene 10970
HGNC 16991
UniProt Q07065  
 CKAP4 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Urine 19056867    
 Gene ontology annotations for CKAP4
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Subcellular Localization
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum lumen GO:0005788 TAS
    endoplasmic reticulum membrane GO:0005789 IEA
    rough endoplasmic reticulum GO:0005791 IBA
    rough endoplasmic reticulum GO:0005791 IDA
    lipid droplet GO:0005811 IDA
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 TAS
    azurophil granule membrane GO:0035577 TAS
    specific granule membrane GO:0035579 TAS
    lamellar body GO:0042599 TAS
    perinuclear region of cytoplasm GO:0048471 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified CKAP4 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 207
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 407
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 405
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 417
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 411
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 418
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 413
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 211
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 212
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 406
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 415
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 408
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 409
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 416
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 834
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 835
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 410
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CKAP4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Proximity Label-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
4 GJD3  
Proximity Label-MS Homo sapiens
5 ISG15 9636
Affinity Capture-MS Homo sapiens
6 RIN3  
Affinity Capture-MS Homo sapiens
7 JPH1 56704
Proximity Label-MS Homo sapiens
8 VMP1 81671
Proximity Label-MS Homo sapiens
9 KIF20A 10112
Affinity Capture-MS Homo sapiens
10 THOC7 80145
Two-hybrid Homo sapiens
11 ST7  
Proximity Label-MS Homo sapiens
12 ARHGAP1 392
Proximity Label-MS Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
14 ARMC7  
Affinity Capture-MS Homo sapiens
15 KIF23 9493
Affinity Capture-MS Homo sapiens
16 OSBPL9 114883
Proximity Label-MS Homo sapiens
17 APBB2  
Proximity Label-MS Homo sapiens
18 SMPD4 55627
Proximity Label-MS Homo sapiens
19 CPSF7 79869
Affinity Capture-MS Homo sapiens
20 MARCH5  
Proximity Label-MS Homo sapiens
21 USP33  
Proximity Label-MS Homo sapiens
22 SLC25A46 91137
Proximity Label-MS Homo sapiens
23 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 SLC6A15 55117
Proximity Label-MS Homo sapiens
25 NEIL3  
Protein-RNA Homo sapiens
26 KIF14 9928
Affinity Capture-MS Homo sapiens
27 NOTCH2 4853
Proximity Label-MS Homo sapiens
28 CAMLG 819
Proximity Label-MS Homo sapiens
29 BAG5 9529
Affinity Capture-MS Homo sapiens
30 SENP2 59343
Proximity Label-MS Homo sapiens
31 NRSN1  
Affinity Capture-MS Homo sapiens
32 ADPGK 83440
Affinity Capture-MS Homo sapiens
33 TMX1 81542
Proximity Label-MS Homo sapiens
34 GGT7 2686
Proximity Label-MS Homo sapiens
35 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
36 UBXN8  
Proximity Label-MS Homo sapiens
37 CLCC1 23155
Proximity Label-MS Homo sapiens
38 OGT 8473
Reconstituted Complex Homo sapiens
39 RPL31 6160
Proximity Label-MS Homo sapiens
40 PIGT 51604
Affinity Capture-MS Homo sapiens
41 GORASP2 26003
Proximity Label-MS Homo sapiens
42 SNAP29 9342
Proximity Label-MS Homo sapiens
43 LYPD6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
45 CSNK1E 1454
Affinity Capture-MS Homo sapiens
46 HECTD1 25831
Affinity Capture-MS Homo sapiens
47 SND1 27044
Proximity Label-MS Homo sapiens
48 SEC61B 10952
Proximity Label-MS Homo sapiens
49 SP100 6672
Affinity Capture-MS Homo sapiens
50 REEP5 7905
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
51 ANLN 54443
Affinity Capture-MS Homo sapiens
52 HSPA5 3309
Proximity Label-MS Homo sapiens
53 ANO6 196527
Proximity Label-MS Homo sapiens
54 HIST1H3F 8968
Proximity Label-MS Homo sapiens
55 AGPAT1 10554
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
56 DHCR7 1717
Proximity Label-MS Homo sapiens
57 SDHA 6389
Affinity Capture-MS Homo sapiens
58 ZNF622 90441
Proximity Label-MS Homo sapiens
59 GGH 8836
Affinity Capture-MS Homo sapiens
60 GOLT1B 51026
Affinity Capture-MS Homo sapiens
61 FEZ1  
Affinity Capture-MS Homo sapiens
62 BCAP31 10134
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
63 TMEM199  
Proximity Label-MS Homo sapiens
64 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
65 FKBP8 23770
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
66 MIA3 375056
Proximity Label-MS Homo sapiens
67 SNX19  
Proximity Label-MS Homo sapiens
68 SAAL1 113174
Affinity Capture-MS Homo sapiens
69 SOAT1 6646
Proximity Label-MS Homo sapiens
70 RPA3 6119
Proximity Label-MS Homo sapiens
71 TMCO1 54499
Proximity Label-MS Homo sapiens
72 RINT1 60561
Proximity Label-MS Homo sapiens
73 DLST 1743
Affinity Capture-MS Homo sapiens
74 LMF2 91289
Proximity Label-MS Homo sapiens
75 EIF3CL 728689
Proximity Label-MS Homo sapiens
76 FAM169A  
Proximity Label-MS Homo sapiens
77 TMEM214 54867
Proximity Label-MS Homo sapiens
78 CYP2C9  
Proximity Label-MS Homo sapiens
79 MALL  
Affinity Capture-MS Homo sapiens
80 RPS16 6217
Affinity Capture-MS Homo sapiens
81 YIF1B 90522
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 NUDT21 11051
Affinity Capture-MS Homo sapiens
83 HMGCR  
Proximity Label-MS Homo sapiens
84 TMEM57  
Proximity Label-MS Homo sapiens
85 AGPAT9  
Proximity Label-MS Homo sapiens
86 RBM25 58517
Affinity Capture-MS Homo sapiens
87 ZEB1  
Affinity Capture-MS Homo sapiens
88 CLPTM1 1209
Proximity Label-MS Homo sapiens
89 VSIG8  
Affinity Capture-MS Homo sapiens
90 PTPN2 5771
Proximity Label-MS Homo sapiens
91 PTDSS1 9791
Proximity Label-MS Homo sapiens
92 G3BP2 9908
Affinity Capture-MS Homo sapiens
93 WIF1 11197
Affinity Capture-MS Homo sapiens
94 RABL3 285282
Proximity Label-MS Homo sapiens
95 HM13 81502
Proximity Label-MS Homo sapiens
96 ARHGAP36  
Affinity Capture-MS Homo sapiens
97 NDC1 55706
Proximity Label-MS Homo sapiens
98 HIST1H4J 8363
Proximity Label-MS Homo sapiens
99 EPHA2 1969
Proximity Label-MS Homo sapiens
100 EI24  
Proximity Label-MS Homo sapiens
101 CISD2 493856
Proximity Label-MS Homo sapiens
102 CUL7 9820
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 RAB5C 5878
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
104 PRAF2 11230
Proximity Label-MS Homo sapiens
105 VANGL1 81839
Proximity Label-MS Homo sapiens
106 VAV3 10451
Affinity Capture-MS Homo sapiens
107 ARHGEF10L 55160
Affinity Capture-MS Homo sapiens
108 HSPA1B 3304
Proximity Label-MS Homo sapiens
109 CD274 29126
Affinity Capture-MS Homo sapiens
110 DERL1 79139
Proximity Label-MS Homo sapiens
111 C2CD2L 9854
Proximity Label-MS Homo sapiens
112 PDHA1 5160
Affinity Capture-MS Homo sapiens
113 Tmed2 56334
Affinity Capture-MS Mus musculus
114 GPR151  
Affinity Capture-MS Homo sapiens
115 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
116 ATL1 51062
Proximity Label-MS Homo sapiens
117 ARHGAP39  
Affinity Capture-MS Homo sapiens
118 METTL7A 25840
Proximity Label-MS Homo sapiens
119 LAMP3  
Proximity Label-MS Homo sapiens
120 SLC39A4 55630
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 GJA1 2697
Proximity Label-MS Homo sapiens
122 KCTD10 83892
Affinity Capture-MS Homo sapiens
123 FRMD3  
Affinity Capture-MS Homo sapiens
124 RPA2 6118
Proximity Label-MS Homo sapiens
125 NOP56 10528
Proximity Label-MS Homo sapiens
126 SRPR 6734
Proximity Label-MS Homo sapiens
127 FFAR1  
Affinity Capture-MS Homo sapiens
128 SERINC2 347735
Affinity Capture-MS Homo sapiens
129 GOLGA7 51125
Affinity Capture-MS Homo sapiens
130 B3GNT2 10678
Affinity Capture-MS Homo sapiens
131 WDR41  
Proximity Label-MS Homo sapiens
132 ELOVL2  
Proximity Label-MS Homo sapiens
133 STS 412
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 CCDC53 51019
Two-hybrid Homo sapiens
135 OBSL1 23363
Affinity Capture-MS Homo sapiens
136 FANCD2  
Affinity Capture-MS Homo sapiens
137 STX18 53407
Proximity Label-MS Homo sapiens
138 TOR3A 64222
Affinity Capture-MS Homo sapiens
139 TACO1  
Affinity Capture-MS Homo sapiens
140 ARMCX3 51566
Co-fractionation Homo sapiens
141 LMAN1 3998
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
142 KIAA1715 80856
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
143 GRIA1  
Affinity Capture-MS Homo sapiens
144 CHMP7 91782
Proximity Label-MS Homo sapiens
145 HS2ST1 9653
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
147 USP10 9100
Affinity Capture-MS Homo sapiens
148 SCD5  
Proximity Label-MS Homo sapiens
149 AMFR 267
Affinity Capture-MS Homo sapiens
150 SMIM12  
Proximity Label-MS Homo sapiens
151 ATF4  
Two-hybrid Homo sapiens
152 SNAP47 116841
Proximity Label-MS Homo sapiens
153 CDKAL1  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
154 TUBA1C 84790
Proximity Label-MS Homo sapiens
155 PMAIP1  
Affinity Capture-MS Homo sapiens
156 TRPM7 54822
Proximity Label-MS Homo sapiens
157 TAPT1 202018
Proximity Label-MS Homo sapiens
158 JAG2  
Proximity Label-MS Homo sapiens
159 PREB 10113
Proximity Label-MS Homo sapiens
160 LYAR 55646
Affinity Capture-MS Homo sapiens
161 STX5 6811
Proximity Label-MS Homo sapiens
162 UPK1A 11045
Affinity Capture-MS Homo sapiens
163 TMEM131  
Proximity Label-MS Homo sapiens
164 HAUS7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 Ksr1  
Affinity Capture-MS Mus musculus
166 DNAJC5B  
Affinity Capture-MS Homo sapiens
167 KDF1  
Affinity Capture-MS Homo sapiens
168 Rmdn3  
Affinity Capture-MS Mus musculus
169 PER2  
Proximity Label-MS Homo sapiens
170 CLN3 1201
Affinity Capture-MS Homo sapiens
171 RPN2 6185
Proximity Label-MS Homo sapiens
172 CANX 821
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
173 EMC8 10328
Proximity Label-MS Homo sapiens
174 RAB5A 5868
Proximity Label-MS Homo sapiens
175 ADCY9 115
Proximity Label-MS Homo sapiens
176 RAB11A 8766
Proximity Label-MS Homo sapiens
177 BRD8 10902
Affinity Capture-MS Homo sapiens
178 FUS 2521
Affinity Capture-MS Homo sapiens
179 TMEM194A  
Proximity Label-MS Homo sapiens
180 TMEM169  
Affinity Capture-MS Homo sapiens
181 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
182 ARHGAP25  
Affinity Capture-MS Homo sapiens
183 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 ATP2A1 487
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 FAM134B 54463
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
186 VRK2 7444
Proximity Label-MS Homo sapiens
187 Junb  
Affinity Capture-MS Mus musculus
188 DDRGK1 65992
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
189 XRCC3  
Affinity Capture-MS Homo sapiens
190 TMEM209 84928
Proximity Label-MS Homo sapiens
191 VIMP 55829
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
192 LEMD3  
Proximity Label-MS Homo sapiens
193 BRD9 65980
Affinity Capture-MS Homo sapiens
194 TRIM13  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
195 TMEM9 252839
Proximity Label-MS Homo sapiens
196 PARP1 142
Affinity Capture-MS Homo sapiens
197 HDGF 3068
Affinity Capture-MS Homo sapiens
198 TP53 7157
Affinity Capture-MS Homo sapiens
199 PGRMC1 10857
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
200 C3AR1  
Affinity Capture-MS Homo sapiens
201 CDCA3 83461
Proximity Label-MS Homo sapiens
202 PDCL 5082
Proximity Label-MS Homo sapiens
203 CALU 813
Proximity Label-MS Homo sapiens
204 Arhgap30  
Affinity Capture-MS Mus musculus
205 NSDHL 50814
Proximity Label-MS Homo sapiens
206 MLH1 4292
Two-hybrid Homo sapiens
207 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
208 MMGT1 93380
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
209 ESR1  
Affinity Capture-MS Homo sapiens
210 AUP1 550
Proximity Label-MS Homo sapiens
211 ERGIC2 51290
Proximity Label-MS Homo sapiens
212 MED21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 TECTB  
Affinity Capture-MS Homo sapiens
214 EEF1D 1936
Affinity Capture-MS Homo sapiens
215 ARHGAP29 9411
Affinity Capture-MS Homo sapiens
216 PRDX1 5052
Cross-Linking-MS (XL-MS) Homo sapiens
217 YKT6 10652
Proximity Label-MS Homo sapiens
218 IGF2R 3482
Proximity Label-MS Homo sapiens
219 DDX42 11325
Affinity Capture-MS Homo sapiens
220 KRAS 3845
Proximity Label-MS Homo sapiens
221 SH3KBP1 30011
Affinity Capture-MS Homo sapiens
222 CKAP4 10970
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
223 KIAA0922  
Proximity Label-MS Homo sapiens
224 CALR3  
Proximity Label-MS Homo sapiens
225 MVP 9961
Two-hybrid Homo sapiens
226 HACD3 51495
Affinity Capture-MS Homo sapiens
227 LYPD3 27076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 MARCKS 4082
Proximity Label-MS Homo sapiens
229 SCYL1 57410
Proximity Label-MS Homo sapiens
230 MTX1 4580
Co-fractionation Homo sapiens
231 Chmp4b 75608
Affinity Capture-MS Mus musculus
232 SYNE2 23224
Proximity Label-MS Homo sapiens
233 PTPN1 5770
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
234 APBB1  
Proximity Label-MS Homo sapiens
235 Ktn1  
Affinity Capture-MS Mus musculus
236 STX4 6810
Proximity Label-MS Homo sapiens
237 RTN4 57142
Proximity Label-MS Homo sapiens
238 TEX264 51368
Proximity Label-MS Homo sapiens
239 TNFRSF10B 8795
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
240 ARL6IP5 10550
Proximity Label-MS Homo sapiens
241 MCM2 4171
Affinity Capture-MS Homo sapiens
242 COPB2 9276
Proximity Label-MS Homo sapiens
243 RAB3B 5865
Proximity Label-MS Homo sapiens
244 FBXO28  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
245 LSG1  
Proximity Label-MS Homo sapiens
246 SSR1 6745
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
247 SCD 6319
Proximity Label-MS Homo sapiens
248 PDIA6 10130
Affinity Capture-MS Homo sapiens
249 CCDC47 57003
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
250 ATG16L1 55054
Affinity Capture-MS Homo sapiens
251 MXRA7 439921
Proximity Label-MS Homo sapiens
252 MTDH 92140
Proximity Label-MS Homo sapiens
253 PKN2 5586
Affinity Capture-MS Homo sapiens
254 ESYT2 57488
Proximity Label-MS Homo sapiens
255 SSMEM1  
Affinity Capture-MS Homo sapiens
256 Arhgap1 228359
Affinity Capture-MS Mus musculus
257 DHRS7 51635
Proximity Label-MS Homo sapiens
258 NUP155 9631
Proximity Label-MS Homo sapiens
259 PXMP2  
Proximity Label-MS Homo sapiens
260 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
261 EIF2AK3  
Proximity Label-MS Homo sapiens
262 SCFD1 23256
Proximity Label-MS Homo sapiens
263 NDUFB7 4713
Two-hybrid Homo sapiens
264 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
265 OSBPL8 114882
Proximity Label-MS Homo sapiens
266 CXADR 1525
Proximity Label-MS Homo sapiens
267 PPIL4  
Affinity Capture-MS Homo sapiens
268 RAB4A 5867
Proximity Label-MS Homo sapiens
269 RGS3 5998
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 NTRK1 4914
Affinity Capture-MS Homo sapiens
271 OSBPL2 9885
Proximity Label-MS Homo sapiens
272 TACC1 6867
Proximity Label-MS Homo sapiens
273 RPN1 6184
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
274 RMDN3 55177
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
275 INTS4P2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
276 SLC4A7 9497
Proximity Label-MS Homo sapiens
277 Rab5c 19345
Affinity Capture-MS Mus musculus
278 SARAF  
Affinity Capture-MS Homo sapiens
279 SMCR8 140775
Proximity Label-MS Homo sapiens
280 DNAJB12 54788
Proximity Label-MS Homo sapiens
281 ECT2 1894
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
282 HSD3B7 80270
Proximity Label-MS Homo sapiens
283 NR3C1 2908
Proximity Label-MS Homo sapiens
284 STIM1 6786
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
285 LPAR1 1902
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 OSBPL11 114885
Proximity Label-MS Homo sapiens
287 PSPC1 55269
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
288 ASCC2 84164
Two-hybrid Homo sapiens
289 EMC2 9694
Affinity Capture-MS Homo sapiens
290 RAB9A 9367
Proximity Label-MS Homo sapiens
291 DNAJC10 54431
Proximity Label-MS Homo sapiens
292 DNAJC3 5611
Proximity Label-MS Homo sapiens
293 DHFRL1  
Proximity Label-MS Homo sapiens
294 KTN1 3895
Proximity Label-MS Homo sapiens
295 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
296 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
297 UBXN4 23190
Proximity Label-MS Homo sapiens
298 ACBD5 91452
Proximity Label-MS Homo sapiens
299 UBE2J1 51465
Proximity Label-MS Homo sapiens
300 MBOAT7 79143
Proximity Label-MS Homo sapiens
301 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
302 ALDH3A2 224
Proximity Label-MS Homo sapiens
303 GPR89A  
Proximity Label-MS Homo sapiens
304 RAB3GAP2 25782
Proximity Label-MS Homo sapiens
305 FBXL6  
Affinity Capture-MS Homo sapiens
306 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
307 THUMPD3 25917
Proximity Label-MS Homo sapiens
308 SEMA7A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 RTN3 10313
Proximity Label-MS Homo sapiens
310 TMA16  
Affinity Capture-MS Homo sapiens
311 ABL1 25
Affinity Capture-MS Homo sapiens
312 REEP2  
Proximity Label-MS Homo sapiens
313 ERGIC1 57222
Proximity Label-MS Homo sapiens
314 PDZD8 118987
Proximity Label-MS Homo sapiens
315 UFL1 23376
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
316 MBNL1 4154
Affinity Capture-MS Homo sapiens
317 INF2 64423
Proximity Label-MS Homo sapiens
318 KCNA10  
Affinity Capture-MS Homo sapiens
319 RAB7A 7879
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
320 TMEM38B  
Proximity Label-MS Homo sapiens
321 AGPAT6 137964
Proximity Label-MS Homo sapiens
322 STT3B 201595
Proximity Label-MS Homo sapiens
323 IPPK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
324 CCR1  
Affinity Capture-MS Homo sapiens
325 HIST1H2AE 3012
Proximity Label-MS Homo sapiens
326 SPCS2 9789
Proximity Label-MS Homo sapiens
327 EP300 2033
Affinity Capture-MS Homo sapiens
328 HLA-C 3107
Proximity Label-MS Homo sapiens
329 DNAJC22  
Proximity Label-MS Homo sapiens
330 UBE2H 7328
Affinity Capture-MS Homo sapiens
331 SLFN11 91607
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
332 RAMP3  
Affinity Capture-MS Homo sapiens
333 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
334 HSD17B11 51170
Proximity Label-MS Homo sapiens
335 POR 5447
Proximity Label-MS Homo sapiens
336 ANKLE2 23141
Proximity Label-MS Homo sapiens
337 VAPA 9218
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
338 HSPA13 6782
Proximity Label-MS Homo sapiens
339 LAMP2 3920
Proximity Label-MS Homo sapiens
340 DNAJC25 548645
Proximity Label-MS Homo sapiens
341 GRAMD1A  
Proximity Label-MS Homo sapiens
342 PDE3B  
Proximity Label-MS Homo sapiens
343 HSD17B12 51144
Proximity Label-MS Homo sapiens
344 SLC12A2 6558
Proximity Label-MS Homo sapiens
345 FNDC5  
Affinity Capture-MS Homo sapiens
346 TMPO 7112
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
347 KIAA1429 25962
Affinity Capture-MS Homo sapiens
348 SRP54 6729
Proximity Label-MS Homo sapiens
349 B3GAT1  
Proximity Label-MS Homo sapiens
350 TSNAX 7257
Two-hybrid Homo sapiens
351 STIM2 57620
Proximity Label-MS Homo sapiens
352 COPS5 10987
Affinity Capture-MS Homo sapiens
353 FBXW7  
Affinity Capture-MS Homo sapiens
354 STX7 8417
Proximity Label-MS Homo sapiens
355 PRELP 5549
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
356 RTN1 6252
Proximity Label-MS Homo sapiens
357 PGRMC2 10424
Proximity Label-MS Homo sapiens
358 DNAJC16  
Proximity Label-MS Homo sapiens
359 NFXL1 152518
Proximity Label-MS Homo sapiens
360 PHF11 51131
Affinity Capture-MS Homo sapiens
361 RAB35 11021
Proximity Label-MS Homo sapiens
362 MYCN  
Affinity Capture-MS Homo sapiens
363 FAF2 23197
Proximity Label-MS Homo sapiens
364 C18orf21  
Affinity Capture-MS Homo sapiens
365 FAM20C 56975
Affinity Capture-MS Homo sapiens
366 TMEM63B 55362
Affinity Capture-MS Homo sapiens
367 LRRC59 55379
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
368 RNF144A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
369 COLEC10 10584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
370 EMD 2010
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
371 RB1CC1 9821
Affinity Capture-MS Homo sapiens
372 CCPG1 9236
Proximity Label-MS Homo sapiens
373 Vav2  
Affinity Capture-MS Mus musculus
374 CYB5A 1528
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
375 S1PR1 1901
Affinity Capture-MS Homo sapiens
376 DNAJB9 4189
Proximity Label-MS Homo sapiens
377 AP1B1 162
Affinity Capture-MS Homo sapiens
378 ADRA1D  
Affinity Capture-MS Homo sapiens
379 SSUH2  
Affinity Capture-MS Homo sapiens
380 STX6 10228
Proximity Label-MS Homo sapiens
381 DDX54 79039
Proximity Label-MS Homo sapiens
382 CRY2  
Affinity Capture-MS Homo sapiens
383 TMX4 56255
Proximity Label-MS Homo sapiens
384 DNAJC30  
Proximity Label-MS Homo sapiens
385 RHOT2 89941
Proximity Label-MS Homo sapiens
386 ELOVL5 60481
Proximity Label-MS Homo sapiens
387 SLC33A1 9197
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
388 DNAJB11 51726
Proximity Label-MS Homo sapiens
389 SLC7A1 6541
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
390 ACBD3 64746
Proximity Label-MS Homo sapiens
391 COX4I1 1327
Proximity Label-MS Homo sapiens
392 TEX2 55852
Proximity Label-MS Homo sapiens
393 SEC63 11231
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
394 PRKCZ 5590
Affinity Capture-MS Homo sapiens
395 PKMYT1  
Proximity Label-MS Homo sapiens
396 CYB5B 80777
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
397 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
398 VAPB 9217
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
399 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
400 PANX1 24145
Proximity Label-MS Homo sapiens
401 ATP2B1 490
Proximity Label-MS Homo sapiens
402 HMOX2 3163
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
403 LAMP1 3916
Proximity Label-MS Homo sapiens
404 Bmpr1a  
Affinity Capture-MS Mus musculus
405 RTN4R 65078
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
406 ARF1 375
Proximity Label-MS Homo sapiens
407 ARF6 382
Proximity Label-MS Homo sapiens
408 NXF1 10482
Affinity Capture-RNA Homo sapiens
409 CHRNA9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
410 ACSL3 2181
Proximity Label-MS Homo sapiens
411 LMNB1 4001
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
412 Abr 109934
Affinity Capture-MS Mus musculus
413 FNDC3A 22862
Proximity Label-MS Homo sapiens
414 STBD1 8987
Proximity Label-MS Homo sapiens
415 B3GAT3 26229
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
416 VDAC1 7416
Co-fractionation Homo sapiens
417 CCDC8  
Affinity Capture-MS Homo sapiens
418 LBR 3930
Proximity Label-MS Homo sapiens
419 USE1 55850
Proximity Label-MS Homo sapiens
420 USP50  
Affinity Capture-MS Homo sapiens
421 RRBP1 6238
Proximity Label-MS Homo sapiens
422 NUP133 55746
Proximity Label-MS Homo sapiens
423 MAST3  
Affinity Capture-MS Homo sapiens
424 SYAP1 94056
Proximity Label-MS Homo sapiens
425 SRP72 6731
Proximity Label-MS Homo sapiens
426 PDIA4 9601
Proximity Label-MS Homo sapiens
427 RAB3GAP1 22930
Proximity Label-MS Homo sapiens
428 TPTE  
Proximity Label-MS Homo sapiens
429 LGALS3 3958
Affinity Capture-MS Homo sapiens
430 TYW1  
Proximity Label-MS Homo sapiens
431 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
432 HIST1H2BD 3017
Proximity Label-MS Homo sapiens
433 DOLPP1  
Proximity Label-MS Homo sapiens
434 NUP98 4928
Proximity Label-MS Homo sapiens
435 UBB 7314
Proximity Label-MS Homo sapiens
436 CLMN  
Proximity Label-MS Homo sapiens
437 LRPAP1 4043
Affinity Capture-MS Homo sapiens
438 MOV10 4343
Affinity Capture-RNA Homo sapiens
439 SEC62 7095
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
440 ARRB1 408
Affinity Capture-MS Homo sapiens
441 PINK1  
Affinity Capture-MS Homo sapiens
442 SLC6A8 6535
Proximity Label-MS Homo sapiens
443 CDK5RAP3 80279
Proximity Label-MS Homo sapiens
444 DNAJC1 64215
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
445 ESYT1 23344
Proximity Label-MS Homo sapiens
446 VEZT 55591
Proximity Label-MS Homo sapiens
447 HAMP  
Two-hybrid Homo sapiens
448 DSG2 1829
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here