Gene description for ABCG2
Gene name	ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
Gene symbol	ABCG2
Other names/aliases	ABC15 ABCP BCRP BCRP1 BMDP CD338 CDw338 EST157481 GOUT1 MRX MXR MXR1 UAQTL1
Species	Homo sapiens
Database cross references - ABCG2
ExoCarta	ExoCarta_9429
Vesiclepedia	VP_9429
Entrez Gene	9429
HGNC	74
MIM	603756
UniProt	Q9UNQ0
ABCG2 identified in sEVs derived from the following tissue/cell type
Breast cancer cells	25833198
Breast milk	17641064
Breast milk	17641064
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246
Colorectal cancer cells	25890246

Gene ontology annotations for ABCG2

Molecular Function     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     organic anion transmembrane transporter activity GO:0008514 ISS     ABC-type xenobiotic transporter activity GO:0008559 IDA     urate transmembrane transporter activity GO:0015143 IDA     urate transmembrane transporter activity GO:0015143 IMP     biotin transmembrane transporter activity GO:0015225 ISS     efflux transmembrane transporter activity GO:0015562 IBA     efflux transmembrane transporter activity GO:0015562 IMP     efflux transmembrane transporter activity GO:0015562 ISS     ATP hydrolysis activity GO:0016887 IEA     riboflavin transmembrane transporter activity GO:0032217 IBA     riboflavin transmembrane transporter activity GO:0032217 IDA     ATPase-coupled transmembrane transporter activity GO:0042626 IBA     ATPase-coupled transmembrane transporter activity GO:0042626 IMP     identical protein binding GO:0042802 IPI     protein homodimerization activity GO:0042803 IDA     xenobiotic transmembrane transporter activity GO:0042910 ISS     sphingolipid transporter activity GO:0046624 TAS Biological Process     lipid transport GO:0006869 IEA     organic anion transport GO:0015711 ISS     urate transport GO:0015747 IEA     biotin transport GO:0015878 ISS     sphingolipid biosynthetic process GO:0030148 TAS     riboflavin transport GO:0032218 IDA     urate metabolic process GO:0046415 IMP     transmembrane transport GO:0055085 IBA     transmembrane transport GO:0055085 IMP     transepithelial transport GO:0070633 IDA     renal urate salt excretion GO:0097744 IMP     export across plasma membrane GO:0140115 ISS     transport across blood-brain barrier GO:0150104 NAS     cellular detoxification GO:1990748 IDA     xenobiotic transport across blood-brain barrier GO:1990962 IC     xenobiotic transport across blood-brain barrier GO:1990962 IDA Subcellular Localization     nucleoplasm GO:0005654 IDA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     apical plasma membrane GO:0016324 ISS     apical plasma membrane GO:0016324 TAS     brush border membrane GO:0031526 IDA     mitochondrial membrane GO:0031966 IEA     membrane raft GO:0045121 IDA     external side of apical plasma membrane GO:0098591 ISS