Gene description for KCNN4
Gene name	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
Gene symbol	KCNN4
Other names/aliases	IK IK1 IKCA1 KCA4 KCa3.1 SK4 hIKCa1 hKCa4 hSK4
Species	Homo sapiens
Database cross references - KCNN4
ExoCarta	ExoCarta_3783
Entrez Gene	3783
HGNC	6293
MIM	602754
UniProt	O15554
KCNN4 identified in exosomes derived from the following tissue/cell type
Melanoma cells	25950383
Melanoma cells	25950383
Prostate cancer cells	25844599

Gene ontology annotations for KCNN4

Molecular Function     Intermediate conductance calcium-activated potassium channel activity GO:0022894 IBA     small conductance calcium-activated potassium channel activity GO:0016286 IBA     calcium-activated potassium channel activity GO:0015269 IDA     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IBA     protein phosphatase binding GO:0019903 IPI Biological Process     cell volume homeostasis GO:0006884 IEA     stabilization of membrane potential GO:0030322 IDA     saliva secretion GO:0046541 IEA     synaptic transmission GO:0007268 TAS     potassium ion transport GO:0006813 TAS     defense response GO:0006952 TAS     potassium ion export GO:0071435 IEA     positive regulation of protein secretion GO:0050714 IEA     phospholipid translocation GO:0045332 IEA     immune system process GO:0002376 IEA     positive regulation of T cell receptor signaling pathway GO:0050862 IDA     potassium ion transmembrane transport GO:0071805 IBA     calcium ion transport GO:0006816 IDA Subcellular Localization     apical plasma membrane GO:0016324 IEA     basolateral plasma membrane GO:0016323 IEA     plasma membrane GO:0005886 TAS     membrane raft GO:0045121 IEA     voltage-gated potassium channel complex GO:0008076 IC     neuronal cell body GO:0043025 IBA