Gene description for FGFR1
Gene name	fibroblast growth factor receptor 1
Gene symbol	FGFR1
Other names/aliases	BFGFR CD331 CEK FGFBR FGFR-1 FLG FLT-2 FLT2 HBGFR HH2 HRTFDS KAL2 N-SAM OGD bFGF-R-1
Species	Homo sapiens
Database cross references - FGFR1
ExoCarta	ExoCarta_2260
Entrez Gene	2260
HGNC	3688
MIM	136350
UniProt	P11362
FGFR1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927

Gene ontology annotations for FGFR1

Molecular Function     protein tyrosine kinase activity GO:0004713 IDA     fibroblast growth factor-activated receptor activity GO:0005007 TAS     ATP binding GO:0005524 IEA     protein homodimerization activity GO:0042803 IPI     protein binding GO:0005515 IPI     heparin binding GO:0008201 IDA     identical protein binding GO:0042802 IPI     fibroblast growth factor binding GO:0017134 IDA Biological Process     chordate embryonic development GO:0043009 TAS     positive regulation of MAP kinase activity GO:0043406 IDA     middle ear morphogenesis GO:0042474 IEA     positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 TAS     embryonic limb morphogenesis GO:0030326 IEA     midbrain development GO:0030901 IEA     regulation of lateral mesodermal cell fate specification GO:0048378 IEA     phosphatidylinositol-mediated signaling GO:0048015 TAS     neuron migration GO:0001764 TAS     organ induction GO:0001759 IEA     ventricular zone neuroblast division GO:0021847 IEA     protein autophosphorylation GO:0046777 IDA     cell maturation GO:0048469 IEA     protein phosphorylation GO:0006468 NAS     axon guidance GO:0007411 TAS     ureteric bud development GO:0001657 IEA     angiogenesis GO:0001525 IEA     positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway GO:0090080 IEA     skeletal system development GO:0001501 TAS     positive regulation of cardiac muscle cell proliferation GO:0060045 IEA     auditory receptor cell development GO:0060117 IEA     lung-associated mesenchyme development GO:0060484 IEA     fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development GO:0035607 IEA     cell migration GO:0016477 TAS     in utero embryonic development GO:0001701 IEA     positive regulation of MAPK cascade GO:0043410 IMP     Fc-epsilon receptor signaling pathway GO:0038095 TAS     peptidyl-tyrosine phosphorylation GO:0018108 IDA     MAPK cascade GO:0000165 TAS     neurotrophin TRK receptor signaling pathway GO:0048011 TAS     branching involved in salivary gland morphogenesis GO:0060445 IEA     positive regulation of cell proliferation GO:0008284 IMP     skeletal system morphogenesis GO:0048705 TAS     epidermal growth factor receptor signaling pathway GO:0007173 TAS     positive regulation of phospholipase C activity GO:0010863 IDA     outer ear morphogenesis GO:0042473 IEA     regulation of cell differentiation GO:0045595 TAS     positive regulation of neuron differentiation GO:0045666 IMP     insulin receptor signaling pathway GO:0008286 TAS     positive regulation of phospholipase activity GO:0010518 TAS     positive regulation of mesenchymal cell proliferation GO:0002053 IEA     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA     paraxial mesoderm development GO:0048339 IEA     regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 IEA     sensory perception of sound GO:0007605 IEA     regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling GO:0060665 IEA     fibroblast growth factor receptor signaling pathway GO:0008543 TAS     transcription, DNA-templated GO:0006351 IEA     innate immune response GO:0045087 TAS     positive regulation of cell cycle GO:0045787 IEA     inner ear morphogenesis GO:0042472 IEA     chondrocyte differentiation GO:0002062 IEA     mesenchymal cell differentiation GO:0048762 IEA     positive regulation of neuron projection development GO:0010976 IEA Subcellular Localization     cytosol GO:0005829 IEA     plasma membrane GO:0005886 TAS     cytoplasmic membrane-bounded vesicle GO:0016023 IEA     receptor complex GO:0043235 IDA     integral component of membrane GO:0016021 NAS     integral component of plasma membrane GO:0005887 TAS     nucleus GO:0005634 IEA     extracellular region GO:0005576 NAS