Gene description for LRPPRC
Gene name leucine-rich pentatricopeptide repeat containing
Gene symbol LRPPRC
Other names/aliases CLONE-23970
GP130
LRP130
LSFC
Species Homo sapiens
 Database cross references - LRPPRC
ExoCarta ExoCarta_10128
Vesiclepedia VP_10128
Entrez Gene 10128
HGNC 15714
MIM 607544
UniProt P42704  
 LRPPRC identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 17956143    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for LRPPRC
Molecular Function
    single-stranded DNA binding GO:0003697 IEA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 NAS
    mRNA 3'-UTR binding GO:0003730 IBA
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 TAS
    ubiquitin protein ligase binding GO:0031625 IPI
    beta-tubulin binding GO:0048487 IDA
    actin filament binding GO:0051015 IDA
Biological Process
    mitochondrial RNA catabolic process GO:0000957 IEA
    negative regulation of mitochondrial RNA catabolic process GO:0000961 IEA
    autophagy GO:0006914 IEA
    mitochondrion transport along microtubule GO:0047497 TAS
    mRNA transport GO:0051028 IEA
    regulation of mitochondrial translation GO:0070129 IBA
Subcellular Localization
    condensed nuclear chromosome GO:0000794 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nuclear inner membrane GO:0005637 IEA
    nuclear outer membrane GO:0005640 IEA
    nucleoplasm GO:0005654 IEA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 IDA
    mitochondrial matrix GO:0005759 TAS
    cytoskeleton GO:0005856 IDA
    microtubule GO:0005874 IDA
    membrane GO:0016020 HDA
    mitochondrial nucleoid GO:0042645 IDA
    perinuclear region of cytoplasm GO:0048471 IDA
    ribonucleoprotein complex GO:1990904 IEA
 Experiment description of studies that identified LRPPRC in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
20
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
23
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
26
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for LRPPRC
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF2AK4 440275
Affinity Capture-MS Homo sapiens
2 RIN3  
Affinity Capture-MS Homo sapiens
3 PPP1R3D  
Co-fractionation Homo sapiens
4 EBNA-LP  
Affinity Capture-MS
5 MTG2  
Proximity Label-MS Homo sapiens
6 MAP4 4134
Co-fractionation Homo sapiens
7 APOE 348
Co-fractionation Homo sapiens
8 MRPL27 51264
Proximity Label-MS Homo sapiens
9 PNMAL1  
Affinity Capture-MS Homo sapiens
10 MRPL37 51253
Proximity Label-MS Homo sapiens
11 GFM2 84340
Proximity Label-MS Homo sapiens
12 CCDC90B  
Proximity Label-MS Homo sapiens
13 CENPA  
Proximity Label-MS Homo sapiens
14 MRPS18C  
Proximity Label-MS Homo sapiens
15 WDR76  
Affinity Capture-MS Homo sapiens
16 PMPCA 23203
Proximity Label-MS Homo sapiens
17 CCAR2 57805
Co-fractionation Homo sapiens
18 METTL22  
Affinity Capture-MS Homo sapiens
19 PSMD12 5718
Co-fractionation Homo sapiens
20 HSPH1 10808
Co-fractionation Homo sapiens
21 ETFA 2108
Proximity Label-MS Homo sapiens
22 ARMCX3 51566
Co-fractionation Homo sapiens
23 PPEF1  
Affinity Capture-MS Homo sapiens
24 GSPT1 2935
Co-fractionation Homo sapiens
25 ACOT2 10965
Proximity Label-MS Homo sapiens
26 CLPB 81570
Co-fractionation Homo sapiens
27 COMT 1312
Co-fractionation Homo sapiens
28 SLC30A9 10463
Proximity Label-MS Homo sapiens
29 MECP2 4204
Affinity Capture-MS Homo sapiens
30 BCS1L 617
Proximity Label-MS Homo sapiens
31 WDR5 11091
Co-fractionation Homo sapiens
32 VWA8 23078
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
33 WRAP73 49856
Affinity Capture-MS Homo sapiens
34 KIF14 9928
Affinity Capture-MS Homo sapiens
35 FBXL5  
Affinity Capture-MS Homo sapiens
36 RBMX 27316
Proximity Label-MS Homo sapiens
37 MRPL38  
Proximity Label-MS Homo sapiens
38 CHMP4C 92421
Affinity Capture-MS Homo sapiens
39 AURKA 6790
Affinity Capture-MS Homo sapiens
40 CRY1  
Affinity Capture-MS Homo sapiens
41 BRE 9577
Affinity Capture-MS Homo sapiens
42 NT5DC2 64943
Proximity Label-MS Homo sapiens
43 TUFM 7284
Proximity Label-MS Homo sapiens
44 PTP4A3  
Affinity Capture-MS Homo sapiens
45 ESRRB  
Affinity Capture-MS Homo sapiens
46 PABPC1 26986
Co-fractionation Homo sapiens
47 PSMD2 5708
Co-fractionation Homo sapiens
48 MYH9 4627
Co-fractionation Homo sapiens
49 TRIM21 6737
Affinity Capture-MS Homo sapiens
50 REL 5966
Co-fractionation Homo sapiens
51 CECR2  
Two-hybrid Homo sapiens
52 CCDC109B 55013
Proximity Label-MS Homo sapiens
53 PEX14 5195
Co-purification Homo sapiens
54 CYC1 1537
Co-fractionation Homo sapiens
55 MTFMT  
Proximity Label-MS Homo sapiens
56 MTRF1L  
Proximity Label-MS Homo sapiens
57 Bub1  
Affinity Capture-MS Mus musculus
58 SND1 27044
Co-fractionation Homo sapiens
59 VDAC2 7417
Co-fractionation Homo sapiens
60 IQGAP2 10788
Co-fractionation Homo sapiens
61 ACN9  
Proximity Label-MS Homo sapiens
62 CD3EAP  
Co-fractionation Homo sapiens
63 ANLN 54443
Affinity Capture-MS Homo sapiens
64 MRPL14 64928
Proximity Label-MS Homo sapiens
65 HSPA5 3309
Co-fractionation Homo sapiens
66 EARS2  
Proximity Label-MS Homo sapiens
67 WBSCR16  
Proximity Label-MS Homo sapiens
68 HADHB 3032
Co-fractionation Homo sapiens
69 HADHA 3030
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
70 MRPS12  
Proximity Label-MS Homo sapiens
71 KIF15 56992
Co-fractionation Homo sapiens
72 MTIF2 4528
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
73 AHCYL1 10768
Co-fractionation Homo sapiens
74 C9orf78 51759
Affinity Capture-MS Homo sapiens
75 SIRT7  
Affinity Capture-MS Homo sapiens
76 GRK5 2869
Affinity Capture-MS Homo sapiens
77 FOXO1  
Reconstituted Complex Homo sapiens
78 BCAP31 10134
Co-fractionation Homo sapiens
79 CUL3 8452
Affinity Capture-MS Homo sapiens
80 GADD45GIP1  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
81 EIF4E 1977
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
82 EPRS 2058
Co-fractionation Homo sapiens
83 KPNA2 3838
Co-fractionation Homo sapiens
84 FN1 2335
Affinity Capture-MS Homo sapiens
85 STRAP 11171
Co-fractionation Homo sapiens
86 C12orf65  
Proximity Label-MS Homo sapiens
87 PRMT5 10419
Co-fractionation Homo sapiens
88 HNRNPR 10236
Proximity Label-MS Homo sapiens
89 MTG1  
Proximity Label-MS Homo sapiens
90 RPA3 6119
Proximity Label-MS Homo sapiens
91 DLST 1743
Proximity Label-MS Homo sapiens
92 GSTK1 373156
Affinity Capture-MS Homo sapiens
93 MRPL3  
Proximity Label-MS Homo sapiens
94 CLPX 10845
Proximity Label-MS Homo sapiens
95 PSMC5 5705
Co-fractionation Homo sapiens
96 MAGEA6  
Affinity Capture-MS Homo sapiens
97 HAT1 8520
Co-fractionation Homo sapiens
98 DLAT 1737
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
99 PEX3 8504
Proximity Label-MS Homo sapiens
100 MRPL18 29074
Proximity Label-MS Homo sapiens
101 RELA 5970
Co-fractionation Homo sapiens
102 DNAJC28  
Proximity Label-MS Homo sapiens
103 GLS 2744
Proximity Label-MS Homo sapiens
104 PDK3 5165
Proximity Label-MS Homo sapiens
105 AUH 549
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
106 USP49 25862
Affinity Capture-MS Homo sapiens
107 COQ5  
Proximity Label-MS Homo sapiens
108 RUVBL2 10856
Co-fractionation Homo sapiens
109 LARS2 23395
Proximity Label-MS Homo sapiens
110 PSMB7 5695
Co-fractionation Homo sapiens
111 EMC4 51234
Co-fractionation Homo sapiens
112 SKP1 6500
Co-fractionation Homo sapiens
113 SNRPD2 6633
Co-fractionation Homo sapiens
114 ITPR3 3710
Affinity Capture-MS Homo sapiens
115 HSP90AA1 3320
Co-fractionation Homo sapiens
116 C11orf74  
Affinity Capture-MS Homo sapiens
117 SSBP1 6742
Proximity Label-MS Homo sapiens
118 PSMA1 5682
Co-fractionation Homo sapiens
119 NDUFAF3 25915
Proximity Label-MS Homo sapiens
120 NME4 4833
Proximity Label-MS Homo sapiens
121 RUVBL1 8607
Co-fractionation Homo sapiens
122 HNRNPL 3191
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
123 ACOT1 641371
Proximity Label-MS Homo sapiens
124 THNSL1 79896
Proximity Label-MS Homo sapiens
125 MRPS16  
Proximity Label-MS Homo sapiens
126 EPHA2 1969
Proximity Label-MS Homo sapiens
127 PRPF4 9128
Co-fractionation Homo sapiens
128 CUL7 9820
Affinity Capture-MS Homo sapiens
129 ADRM1 11047
Co-fractionation Homo sapiens
130 MRPL53  
Proximity Label-MS Homo sapiens
131 POLG  
Proximity Label-MS Homo sapiens
132 PPP2R2A 5520
Co-fractionation Homo sapiens
133 PPARGC1A  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
134 NDUFS6  
Proximity Label-MS Homo sapiens
135 PSMD3 5709
Co-fractionation Homo sapiens
136 COX5A 9377
Proximity Label-MS Homo sapiens
137 AFG3L2 10939
Proximity Label-MS Homo sapiens
138 KIF23 9493
Affinity Capture-MS Homo sapiens
139 MRPL24  
Proximity Label-MS Homo sapiens
140 MRPL48  
Proximity Label-MS Homo sapiens
141 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 ATP5J2-PTCD1  
Proximity Label-MS Homo sapiens
143 MAGEA3  
Affinity Capture-MS Homo sapiens
144 GTPBP10  
Proximity Label-MS Homo sapiens
145 BTF3 689
Affinity Capture-MS Homo sapiens
146 ADRB2  
Affinity Capture-MS Homo sapiens
147 ALDH2 217
Proximity Label-MS Homo sapiens
148 CHCHD1  
Proximity Label-MS Homo sapiens
149 ZFR 51663
Proximity Label-MS Homo sapiens
150 HSP90AB1 3326
Co-fractionation Homo sapiens
151 NDUFA12 55967
Proximity Label-MS Homo sapiens
152 MRPL50 54534
Proximity Label-MS Homo sapiens
153 MRPL49 740
Proximity Label-MS Homo sapiens
154 MRPL23 6150
Proximity Label-MS Homo sapiens
155 NDUFS2 4720
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
156 WTAP 9589
Affinity Capture-MS Homo sapiens
157 B3GNT2 10678
Affinity Capture-MS Homo sapiens
158 OGDH 4967
Proximity Label-MS Homo sapiens
159 PDK1 5163
Proximity Label-MS Homo sapiens
160 SUPV3L1 6832
Proximity Label-MS Homo sapiens
161 TRMT2B  
Proximity Label-MS Homo sapiens
162 HARS2 23438
Proximity Label-MS Homo sapiens
163 PRC1 9055
Affinity Capture-MS Homo sapiens
164 MRPS23 51649
Proximity Label-MS Homo sapiens
165 NDUFA5 4698
Proximity Label-MS Homo sapiens
166 TBCD 6904
Co-fractionation Homo sapiens
167 KHDRBS1 10657
Co-fractionation Homo sapiens
168 SIRT1  
Affinity Capture-MS Homo sapiens
169 LACTB 114294
Co-fractionation Homo sapiens
170 KLF4  
Cross-Linking-MS (XL-MS) Homo sapiens
171 VCAM1 7412
Affinity Capture-MS Homo sapiens
172 DDX6 1656
Co-fractionation Homo sapiens
173 NDUFV3 4731
Proximity Label-MS Homo sapiens
174 MRPS7 51081
Proximity Label-MS Homo sapiens
175 CUL1 8454
Co-fractionation Homo sapiens
176 PMPCB 9512
Proximity Label-MS Homo sapiens
177 TACO1  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
178 FASTKD2  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
179 HK1 3098
Co-fractionation Homo sapiens
180 SMC2 10592
Co-fractionation Homo sapiens
181 QRSL1  
Proximity Label-MS Homo sapiens
182 LMAN1 3998
Co-fractionation Homo sapiens
183 NNT 23530
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
184 CALM2 805
Affinity Capture-MS Homo sapiens
185 MRPS35 60488
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
186 UFL1 23376
Affinity Capture-MS Homo sapiens
187 C6orf203  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
188 ALDH16A1 126133
Co-fractionation Homo sapiens
189 MRPL45 84311
Proximity Label-MS Homo sapiens
190 CDKN1A  
Affinity Capture-MS Homo sapiens
191 KLC1 3831
Co-fractionation Homo sapiens
192 POLRMT 5442
Proximity Label-MS Homo sapiens
193 PSMD14 10213
Co-fractionation Homo sapiens
194 MRPS18B 28973
Proximity Label-MS Homo sapiens
195 PDHX 8050
Co-fractionation Homo sapiens
196 POLDIP2 26073
Proximity Label-MS Homo sapiens
197 NDUFA2 4695
Proximity Label-MS Homo sapiens
198 UQCRC1 7384
Co-fractionation Homo sapiens
199 PARS2 25973
Co-fractionation Homo sapiens
200 NDUFAF7  
Proximity Label-MS Homo sapiens
201 MRPL39 54148
Proximity Label-MS Homo sapiens
202 RAD21 5885
Affinity Capture-Western Homo sapiens
203 ABCB7 22
Proximity Label-MS Homo sapiens
204 NDUFAF1  
Proximity Label-MS Homo sapiens
205 MRPL44  
Proximity Label-MS Homo sapiens
206 PER2  
Proximity Label-MS Homo sapiens
207 OTC 5009
Proximity Label-MS Homo sapiens
208 IBA57  
Proximity Label-MS Homo sapiens
209 AIFM1 9131
Proximity Label-MS Homo sapiens
210 CANX 821
Co-fractionation Homo sapiens
211 EMC8 10328
Co-fractionation Homo sapiens
212 XPO1 7514
Reconstituted Complex Homo sapiens
213 USP15 9958
Co-fractionation Homo sapiens
214 RC3H2  
Affinity Capture-MS Homo sapiens
215 MRPS11  
Proximity Label-MS Homo sapiens
216 MTIF3  
Proximity Label-MS Homo sapiens
217 ASAH1 427
Co-fractionation Homo sapiens
218 RTN4IP1  
Proximity Label-MS Homo sapiens
219 TNKS1BP1 85456
Co-fractionation Homo sapiens
220 PRKAR2A 5576
Co-fractionation Homo sapiens
221 MRPL9 65005
Proximity Label-MS Homo sapiens
222 ATP5F1 515
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
223 RMND1 55005
Proximity Label-MS Homo sapiens
224 EGFR 1956
Affinity Capture-MS Homo sapiens
225 HSD17B10 3028
Proximity Label-MS Homo sapiens
226 LARS 51520
Co-fractionation Homo sapiens
227 SPTBN1 6711
Co-fractionation Homo sapiens
228 CDK2 1017
Affinity Capture-MS Homo sapiens
229 CEP250 11190
Affinity Capture-MS Homo sapiens
230 PPP2R1A 5518
Co-fractionation Homo sapiens
231 PTGES3 10728
Affinity Capture-MS Homo sapiens
232 SCO1  
Affinity Capture-MS Homo sapiens
233 ACAD9 28976
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
234 DDB1 1642
Co-fractionation Homo sapiens
235 RCN2 5955
Co-fractionation Homo sapiens
236 DDRGK1 65992
Affinity Capture-MS Homo sapiens
237 BMI1  
Affinity Capture-MS Homo sapiens
238 MRPS17 51373
Proximity Label-MS Homo sapiens
239 NDUFV2 4729
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
240 MRPL47 57129
Proximity Label-MS Homo sapiens
241 MCUR1 63933
Proximity Label-MS Homo sapiens
242 HEBP2 23593
Two-hybrid Homo sapiens
243 PPP2CA 5515
Co-fractionation Homo sapiens
244 PPIF 10105
Proximity Label-MS Homo sapiens
245 ZRANB1 54764
Affinity Capture-MS Homo sapiens
246 TRIM5 85363
Affinity Capture-Western Homo sapiens
247 CLPP 8192
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
248 CS 1431
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
249 NFKBIB  
Co-fractionation Homo sapiens
250 C17orf80 55028
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
251 STK24 8428
Affinity Capture-MS Homo sapiens
252 VDAC3 7419
Co-fractionation Homo sapiens
253 ILF3 3609
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
254 H3F3A 3020
Co-fractionation Homo sapiens
255 TP53 7157
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
256 SLK 9748
Co-fractionation Homo sapiens
257 NEK6 10783
Affinity Capture-MS Homo sapiens
258 HSPA8 3312
Affinity Capture-MS Homo sapiens
259 PRKCI 5584
Co-fractionation Homo sapiens
260 BCKDHA 593
Co-fractionation Homo sapiens
261 MRPL28 10573
Proximity Label-MS Homo sapiens
262 CAPZA2 830
Affinity Capture-MS Homo sapiens
263 ATG101  
Affinity Capture-MS Homo sapiens
264 COX8A  
Proximity Label-MS Homo sapiens
265 SHMT2 6472
Affinity Capture-RNA Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
266 MRPS21  
Proximity Label-MS Homo sapiens
267 ESR1  
Affinity Capture-MS Homo sapiens
268 ME2 4200
Proximity Label-MS Homo sapiens
269 FASTKD3  
Proximity Label-MS Homo sapiens
270 NCAPD2 9918
Co-fractionation Homo sapiens
271 GFM1 85476
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
272 TEFM  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
273 MGST3 4259
Co-fractionation Homo sapiens
274 GAPVD1 26130
Co-fractionation Homo sapiens
275 PHACTR3  
Affinity Capture-MS Homo sapiens
276 TIMM44 10469
Proximity Label-MS Homo sapiens
277 C1QBP 708
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
278 ETFDH 2110
Co-fractionation Homo sapiens
279 KRAS 3845
Negative Genetic Homo sapiens
280 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
281 DERL1 79139
Proximity Label-MS Homo sapiens
282 RBBP4 5928
Co-fractionation Homo sapiens
283 IKBKB 3551
Co-fractionation Homo sapiens
284 PRMT1 3276
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
285 MRPS9 64965
Proximity Label-MS Homo sapiens
286 CUL4A 8451
Affinity Capture-MS Homo sapiens
287 MRPS27 23107
Proximity Label-MS Homo sapiens
288 SLIRP 81892
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
289 RAB1A 5861
Co-fractionation Homo sapiens
290 CENPE 1062
Affinity Capture-MS Homo sapiens
291 NDUFS1 4719
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
292 MRPL17  
Proximity Label-MS Homo sapiens
293 NAPA 8775
Co-fractionation Homo sapiens
294 TPP1 1200
Co-fractionation Homo sapiens
295 CD4 920
Affinity Capture-MS Homo sapiens
296 PYCR1 5831
Proximity Label-MS Homo sapiens
297 GATB  
Proximity Label-MS Homo sapiens
298 PSMD10 5716
Co-fractionation Homo sapiens
299 RPS6KB2  
Affinity Capture-MS Homo sapiens
300 ERCC5  
Affinity Capture-MS Homo sapiens
301 CARS2 79587
Proximity Label-MS Homo sapiens
302 CAPZB 832
Affinity Capture-MS Homo sapiens
303 SART3 9733
Affinity Capture-MS Homo sapiens
304 NCBP1 4686
Co-fractionation Homo sapiens
305 NDUFS3 4722
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
306 CRYZ 1429
Proximity Label-MS Homo sapiens
307 MCM2 4171
Affinity Capture-MS Homo sapiens
308 SDHB 6390
Proximity Label-MS Homo sapiens
309 TIMMDC1  
Affinity Capture-MS Homo sapiens
310 SPAG9 9043
Co-fractionation Homo sapiens
311 YARS2  
Proximity Label-MS Homo sapiens
312 HINT2 84681
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
313 IQGAP1 8826
Co-fractionation Homo sapiens
314 POLR1E  
Co-fractionation Homo sapiens
315 PSMC2 5701
Co-fractionation Homo sapiens
316 AASS  
Co-fractionation Homo sapiens
317 ATPAF1  
Proximity Label-MS Homo sapiens
318 IKBKE 9641
Affinity Capture-MS Homo sapiens
319 C20orf24  
Co-fractionation Homo sapiens
320 ITGA4 3676
Affinity Capture-MS Homo sapiens
321 CCDC47 57003
Affinity Capture-MS Homo sapiens
322 NDUFV1 4723
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
323 GOLGA4  
Co-fractionation Homo sapiens
324 MRPL4 51073
Proximity Label-MS Homo sapiens
325 PABPC4 8761
Affinity Capture-MS Homo sapiens
326 MTERF3  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
327 FEN1 2237
Affinity Capture-MS Homo sapiens
328 MDH2 4191
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
329 WAPAL  
Co-fractionation Homo sapiens
330 ALAS1  
Proximity Label-MS Homo sapiens
331 MRPS25 64432
Proximity Label-MS Homo sapiens
332 MRPS33  
Proximity Label-MS Homo sapiens
333 P4HA1 5033
Co-fractionation Homo sapiens
334 THEM4  
Proximity Label-MS Homo sapiens
335 EML4 27436
Co-fractionation Homo sapiens
336 FASTKD5  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
337 PARK2  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
338 RPS10 6204
Co-fractionation Homo sapiens
339 MEX3C 51320
Affinity Capture-MS Homo sapiens
340 PAM16  
Proximity Label-MS Homo sapiens
341 ACACA 31
Co-fractionation Homo sapiens
342 CHMP4B 128866
Affinity Capture-MS Homo sapiens
343 RPA2 6118
Proximity Label-MS Homo sapiens
344 NTRK1 4914
Affinity Capture-MS Homo sapiens
345 U2AF2 11338
Co-fractionation Homo sapiens
346 HNRNPAB 3182
Proximity Label-MS Homo sapiens
347 DNAJA1 3301
Co-fractionation Homo sapiens
348 C10orf2 56652
Proximity Label-MS Homo sapiens
349 KIAA0391  
Proximity Label-MS Homo sapiens
350 MTPAP 55149
Proximity Label-MS Homo sapiens
351 DHX9 1660
Co-fractionation Homo sapiens
352 ZC3H14  
Affinity Capture-MS Homo sapiens
353 MRPL11 65003
Proximity Label-MS Homo sapiens
354 UQCRH 7388
Co-fractionation Homo sapiens
355 NFKB2 4791
Co-fractionation Homo sapiens
356 HDAC5 10014
Affinity Capture-MS Homo sapiens
357 TMEM70  
Proximity Label-MS Homo sapiens
358 MRPL2 51069
Proximity Label-MS Homo sapiens
359 LARP1 23367
Co-fractionation Homo sapiens
360 HNRNPDL 9987
Proximity Label-MS Homo sapiens
361 ASB5  
Affinity Capture-MS Homo sapiens
362 ACAT1 38
Proximity Label-MS Homo sapiens
363 MRPL40 64976
Proximity Label-MS Homo sapiens
364 SLC25A12 8604
Proximity Label-MS Homo sapiens
365 MINOS1  
Co-fractionation Homo sapiens
366 METTL14  
Affinity Capture-MS Homo sapiens
367 TRMT10C 54931
Proximity Label-MS Homo sapiens
368 PNPT1 87178
Proximity Label-MS Homo sapiens
369 TRIM33 51592
Co-fractionation Homo sapiens
370 MRPS6  
Proximity Label-MS Homo sapiens
371 ECT2 1894
Affinity Capture-MS Homo sapiens
372 MRPL10 124995
Proximity Label-MS Homo sapiens
373 ARFGEF1 10565
Co-fractionation Homo sapiens
374 ACADM 34
Proximity Label-MS Homo sapiens
375 NR3C1 2908
Affinity Capture-MS Homo sapiens
376 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
377 DHX30 22907
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
378 HNRNPUL1 11100
Proximity Label-MS Homo sapiens
379 TP73  
Affinity Capture-Western Homo sapiens
380 MRPS28  
Proximity Label-MS Homo sapiens
381 GATC  
Proximity Label-MS Homo sapiens
382 NRBP1 29959
Co-fractionation Homo sapiens
383 NCAPH 23397
Co-fractionation Homo sapiens
384 MRPL19 9801
Proximity Label-MS Homo sapiens
385 EMC2 9694
Co-fractionation Homo sapiens
386 YWHAQ 10971
Co-fractionation Homo sapiens
387 HSDL2 84263
Proximity Label-MS Homo sapiens
388 PPA2 27068
Proximity Label-MS Homo sapiens
389 MRPS36 92259
Proximity Label-MS Homo sapiens
390 FLII 2314
Co-fractionation Homo sapiens
391 RNF2  
Affinity Capture-MS Homo sapiens
392 Kctd5  
Affinity Capture-MS Mus musculus
393 HSPA9 3313
Proximity Label-MS Homo sapiens
394 PUS1 80324
Proximity Label-MS Homo sapiens
395 NEUROG3  
Affinity Capture-MS Homo sapiens
396 METTL15  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
397 AKAP1 8165
Proximity Label-MS Homo sapiens
398 PNKD  
Affinity Capture-MS Homo sapiens
399 NCAPG 64151
Co-fractionation Homo sapiens
400 TPM3 7170
Co-fractionation Homo sapiens
401 HIF1A 3091
Affinity Capture-MS Homo sapiens
402 DBT 1629
Proximity Label-MS Homo sapiens
403 DNAJC4  
Proximity Label-MS Homo sapiens
404 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
405 PHB2 11331
Proximity Label-MS Homo sapiens
406 TSFM 10102
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
407 JUP 3728
Affinity Capture-MS Homo sapiens
408 ATP5J 522
Proximity Label-MS Homo sapiens
409 NDUFAF2  
Proximity Label-MS Homo sapiens
410 POLR1B 84172
Co-fractionation Homo sapiens
411 FBXW11  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
412 MAP1S 55201
Two-hybrid Homo sapiens
413 UQCC1 55245
Proximity Label-MS Homo sapiens
414 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
415 PHLDA3 23612
Affinity Capture-MS Homo sapiens
416 LONP1 9361
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
417 SON 6651
Co-fractionation Homo sapiens
418 TNFRSF10D 8793
Affinity Capture-MS Homo sapiens
419 PDHA1 5160
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
420 GABARAPL2 11345
Affinity Capture-MS Homo sapiens
421 LAMTOR2 28956
Co-fractionation Homo sapiens
422 MRPS10 55173
Proximity Label-MS Homo sapiens
423 DDX58 23586
Affinity Capture-RNA Homo sapiens
424 MYL12A 10627
Co-fractionation Homo sapiens
425 IDH3A 3419
Proximity Label-MS Homo sapiens
426 SPC25 57405
Affinity Capture-MS Homo sapiens
427 GUF1  
Proximity Label-MS Homo sapiens
428 NDUFS8 4728
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
429 MRPL41 64975
Proximity Label-MS Homo sapiens
430 TBRG4 9238
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
431 AARS2  
Proximity Label-MS Homo sapiens
432 TRMT5  
Proximity Label-MS Homo sapiens
433 RAB7A 7879
Affinity Capture-MS Homo sapiens
434 MGME1  
Proximity Label-MS Homo sapiens
435 RPUSD3  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
436 HNRNPF 3185
Co-fractionation Homo sapiens
437 SERBP1 26135
Affinity Capture-MS Homo sapiens
438 BZW1 9689
Co-fractionation Homo sapiens
439 RAC1 5879
Affinity Capture-MS Homo sapiens
440 RC3H1 149041
Affinity Capture-MS Homo sapiens
441 MRPS22 56945
Proximity Label-MS Homo sapiens
442 DDX28  
Proximity Label-MS Homo sapiens
443 IARS2 55699
Proximity Label-MS Homo sapiens
444 LYPLAL1 127018
Proximity Label-MS Homo sapiens
445 UBE2H 7328
Affinity Capture-MS Homo sapiens
446 RIT1 6016
Negative Genetic Homo sapiens
447 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
448 POR 5447
Co-fractionation Homo sapiens
449 ATPIF1 93974
Proximity Label-MS Homo sapiens
450 LGR4 55366
Affinity Capture-MS Homo sapiens
451 COIL  
Proximity Label-MS Homo sapiens
452 PSMD6 9861
Co-fractionation Homo sapiens
453 TRMT61B  
Proximity Label-MS Homo sapiens
454 Cdh1 12550
Affinity Capture-MS Mus musculus
455 PPIE 10450
Affinity Capture-MS Homo sapiens
456 PSMD11 5717
Co-fractionation Homo sapiens
457 FBXO25  
Affinity Capture-MS Homo sapiens
458 TRUB2  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
459 NGRN  
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
460 LSM4 25804
Co-fractionation Homo sapiens
461 ETFB 2109
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
462 KARS 3735
Co-fractionation Homo sapiens
463 CALM1 801
Affinity Capture-MS Homo sapiens
464 TROVE2 6738
Co-fractionation Homo sapiens
465 MRPL52  
Proximity Label-MS Homo sapiens
466 RPUSD4 84881
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
467 MRPS14  
Proximity Label-MS Homo sapiens
468 DNAJC15  
Proximity Label-MS Homo sapiens
469 MTRF1  
Proximity Label-MS Homo sapiens
470 APP 351
Co-fractionation Homo sapiens
471 TMPO 7112
Affinity Capture-MS Homo sapiens
472 HADH 3033
Proximity Label-MS Homo sapiens
473 KIAA1429 25962
Affinity Capture-MS Homo sapiens
474 RNH1 6050
Co-fractionation Homo sapiens
475 KIF20A 10112
Affinity Capture-MS Homo sapiens
476 WAS 7454
Affinity Capture-MS Homo sapiens
477 MRPL20 55052
Proximity Label-MS Homo sapiens
478 TFAM 7019
Proximity Label-MS Homo sapiens
479 NDUFA7 4701
Proximity Label-MS Homo sapiens
480 KIF5B 3799
Co-fractionation Homo sapiens
481 MRPS5 64969
Proximity Label-MS Homo sapiens
482 FBXW7  
Affinity Capture-MS Homo sapiens
483 C8orf82  
Proximity Label-MS Homo sapiens
484 MRPS24 64951
Proximity Label-MS Homo sapiens
485 COA3 28958
Affinity Capture-Western Homo sapiens
486 CALM3 808
Affinity Capture-MS Homo sapiens
487 MRPL12 6182
Proximity Label-MS Homo sapiens
488 PSMC6 5706
Co-fractionation Homo sapiens
489 ATP2A2 488
Co-fractionation Homo sapiens
490 MRPS26 64949
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
491 SURF1  
Proximity Label-MS Homo sapiens
492 ADARB1 104
Co-fractionation Homo sapiens
493 IPO8 10526
Reconstituted Complex Homo sapiens
494 EXD2  
Proximity Label-MS Homo sapiens
495 DGCR2 9993
Affinity Capture-MS Homo sapiens
496 RNMTL1  
Proximity Label-MS Homo sapiens
497 SEC23A 10484
Co-fractionation Homo sapiens
498 SLC4A1AP  
Co-fractionation Homo sapiens
499 MYCN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
500 NDUFA6  
Proximity Label-MS Homo sapiens
501 DAP3 7818
Proximity Label-MS Homo sapiens
502 PSMC3 5702
Co-fractionation Homo sapiens
503 TRIP12 9320
Co-fractionation Homo sapiens
504 SMC4 10051
Co-fractionation Homo sapiens
505 POLR1A 25885
Co-fractionation Homo sapiens
506 MRPS30 10884
Proximity Label-MS Homo sapiens
507 E2F4  
Affinity Capture-MS Homo sapiens
508 LRRC59 55379
Co-fractionation Homo sapiens
509 GEMIN5 25929
Co-fractionation Homo sapiens
510 HAUS2  
Affinity Capture-MS Homo sapiens
511 RBBP7 5931
Co-fractionation Homo sapiens
512 NDUFS4 4724
Proximity Label-MS Homo sapiens
513 COX15 1355
Proximity Label-MS Homo sapiens
514 UXT 8409
Two-hybrid Homo sapiens
515 TGM2 7052
Co-fractionation Homo sapiens
516 MRPS34 65993
Proximity Label-MS Homo sapiens
517 ERBB3 2065
Affinity Capture-MS Homo sapiens
518 HSP90B1 7184
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
519 PSMC1 5700
Co-fractionation Homo sapiens
520 STAU1 6780
Affinity Capture-MS Homo sapiens
521 CPS1 1373
Co-fractionation Homo sapiens
522 PTCD3 55037
Proximity Label-MS Homo sapiens
523 HSCB 150274
Proximity Label-MS Homo sapiens
524 ASPM 259266
Cross-Linking-MS (XL-MS) Homo sapiens
525 MMAB 326625
Proximity Label-MS Homo sapiens
526 VCP 7415
Co-fractionation Homo sapiens
527 PON2 5445
Co-fractionation Homo sapiens
528 CRY2  
Affinity Capture-MS Homo sapiens
529 PML 5371
Affinity Capture-MS Homo sapiens
530 ERAL1  
Proximity Label-MS Homo sapiens
531 MRPL22  
Proximity Label-MS Homo sapiens
532 CEP76  
Affinity Capture-MS Homo sapiens
533 DNAJC30  
Proximity Label-MS Homo sapiens
534 NIPSNAP1 8508
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
535 ATP5B 506
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
536 COX4I1 1327
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
537 OXA1L  
Proximity Label-MS Homo sapiens
538 TOMM40 10452
Co-fractionation Homo sapiens
539 IPO5 3843
Co-fractionation Homo sapiens
540 MRPL21 219927
Proximity Label-MS Homo sapiens
541 MRRF  
Proximity Label-MS Homo sapiens
542 FANCD2  
Affinity Capture-MS Homo sapiens
543 NAA38  
Co-fractionation Homo sapiens
544 MRPL46  
Proximity Label-MS Homo sapiens
545 POLR2H 5437
Co-fractionation Homo sapiens
546 BCKDHB 594
Co-fractionation Homo sapiens
547 OTUD1 220213
Affinity Capture-MS Homo sapiens
548 NDUFA9 4704
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
549 EIF4G1 1981
Co-fractionation Homo sapiens
550 PSMD13 5719
Co-fractionation Homo sapiens
551 LETM1 3954
Proximity Label-MS Homo sapiens
552 UQCRC2 7385
Co-fractionation Homo sapiens
553 HMOX2 3163
Co-fractionation Homo sapiens
554 CTNNB1 1499
Co-fractionation Homo sapiens
555 GCDH 2639
Proximity Label-MS Homo sapiens
556 NFS1 9054
Proximity Label-MS Homo sapiens
557 ELAC2 60528
Proximity Label-MS Homo sapiens
558 ARF6 382
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
559 PYCR2 29920
Proximity Label-MS Homo sapiens
560 ECHS1 1892
Proximity Label-MS Homo sapiens
561 SART1 9092
Co-fractionation Homo sapiens
562 NXF1 10482
Affinity Capture-RNA Homo sapiens
563 MRPL15 29088
Proximity Label-MS Homo sapiens
564 AURKB 9212
Affinity Capture-MS Homo sapiens
565 MRPL1  
Proximity Label-MS Homo sapiens
566 FBXO6 26270
Affinity Capture-MS Homo sapiens
567 ATP6V1A 523
Co-fractionation Homo sapiens
568 USP19 10869
Affinity Capture-MS Homo sapiens
569 ASPH 444
Co-fractionation Homo sapiens
570 RPAP3 79657
Co-fractionation Homo sapiens
571 NFKB1 4790
Co-fractionation Homo sapiens
572 VARS2  
Proximity Label-MS Homo sapiens
573 PDPR 55066
Proximity Label-MS Homo sapiens
574 ATP5C1 509
Co-fractionation Homo sapiens
575 RARS 5917
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
576 CORO1C 23603
Co-fractionation Homo sapiens
577 CCDC8  
Affinity Capture-MS Homo sapiens
578 MTHFD1L 25902
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
579 AK4 205
Proximity Label-MS Homo sapiens
580 MRPL42  
Proximity Label-MS Homo sapiens
581 GLUD1 2746
Proximity Label-MS Homo sapiens
582 PPP2R5E 5529
Co-fractionation Homo sapiens
583 PSMD1 5707
Co-fractionation Homo sapiens
584 DNAJC19 131118
Proximity Label-MS Homo sapiens
585 MRPS2 51116
Proximity Label-MS Homo sapiens
586 DNAJA2 10294
Co-fractionation Homo sapiens
587 ZNF746  
Affinity Capture-MS Homo sapiens
588 MRPS31  
Proximity Label-MS Homo sapiens
589 MRPL43 84545
Proximity Label-MS Homo sapiens
590 DNAJA3 9093
Proximity Label-MS Homo sapiens
591 SMURF1 57154
Affinity Capture-MS Homo sapiens
592 NDUFS7 374291
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
593 HDAC1 3065
Co-fractionation Homo sapiens
594 VTA1 51534
Co-fractionation Homo sapiens
595 SUCLA2 8803
Proximity Label-MS Homo sapiens
596 C21orf33  
Proximity Label-MS Homo sapiens
597 EDEM3 80267
Affinity Capture-MS Homo sapiens
598 STOML2 30968
Proximity Label-MS Homo sapiens
599 SFXN1 94081
Proximity Label-MS Homo sapiens
600 MAGED1 9500
Affinity Capture-MS Homo sapiens
601 MOV10 4343
Affinity Capture-RNA Homo sapiens
602 EZH2  
Affinity Capture-MS Homo sapiens
603 MRPL13  
Proximity Label-MS Homo sapiens
604 CAD 790
Co-fractionation Homo sapiens
605 C19orf52  
Proximity Label-MS Homo sapiens
606 PINK1  
Affinity Capture-MS Homo sapiens
607 GRSF1 2926
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
608 XRCC6 2547
Co-fractionation Homo sapiens
609 NDUFAF4 29078
Proximity Label-MS Homo sapiens
610 HNRNPU 3192
Cross-Linking-MS (XL-MS) Homo sapiens
611 C9orf72  
Affinity Capture-MS Homo sapiens
612 METTL17  
Proximity Label-MS Homo sapiens
613 IVNS1ABP  
Affinity Capture-MS Homo sapiens
614 MRPS18A  
Proximity Label-MS Homo sapiens
615 ECSIT 51295
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which LRPPRC is involved
PathwayEvidenceSource
Metabolism of RNA TAS Reactome
Mitochondrial RNA degradation TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here