Experiment description of studies that identified ARFGEF1 in exosomes

1 Experiment ID 1203 MISEV standards ✔ EM Biophysical techniques ✔ SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 34887515     Organism Homo sapiens Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ." Journal name Nat Cell Biol Publication year 2021 Sample Colorectal cancer cells Sample name DiFi Isolation/purification methods Differential centrifugation Filtration Centrifugal ultrafiltration Ultracentrifugation OptiPrep density gradient centrifugation Flotation density - Molecules identified in the study Protein miRNA Methods used in the study Western blotting Mass spectrometry RNA sequencing

2 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for ARFGEF1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 SGCA   Affinity Capture-MS Homo sapiens 2 GJD3   Proximity Label-MS Homo sapiens 3 AKAP10 11216 Affinity Capture-MS Homo sapiens 4 MSH6 2956 Affinity Capture-MS Homo sapiens 5 LAMP3   Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 GJA1 2697 Proximity Label-MS Homo sapiens 7 PSMA4 5685 Co-fractionation Homo sapiens 8 RPA2 6118 Proximity Label-MS Homo sapiens 9 NUP62 23636 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 10 IGHM 3507 Affinity Capture-MS Homo sapiens 11 FPR1   Affinity Capture-MS Homo sapiens 12 TMEM9B 56674 Affinity Capture-MS Homo sapiens 13 LAMP2 3920 Proximity Label-MS Homo sapiens 14 EDNRB 1910 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 15 KLRB1   Affinity Capture-MS Homo sapiens 16 LRPPRC 10128 Co-fractionation Homo sapiens 17 RIPK3 11035 Affinity Capture-MS Homo sapiens 18 BORA   Affinity Capture-MS Homo sapiens 19 B3GAT1   Proximity Label-MS Homo sapiens 20 TBC1D22A   Affinity Capture-MS Homo sapiens 21 HLA-B 3106 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 MRPL23 6150 Affinity Capture-MS Homo sapiens 23 SPAG9 9043 Co-fractionation Homo sapiens 24 KCNH4   Affinity Capture-MS Homo sapiens 25 PVRIG   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 DDX58 23586 Affinity Capture-RNA Homo sapiens 27 SEMA4C 54910 Affinity Capture-MS Homo sapiens 28 CLEC14A   Affinity Capture-MS Homo sapiens 29 STX6 10228 Proximity Label-MS Homo sapiens 30 ITGA8 8516 Affinity Capture-MS Homo sapiens 31 DGCR2 9993 Affinity Capture-MS Homo sapiens 32 ARFGEF2 10564 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Negative Genetic Homo sapiens 33 EBAG9 9166 Proximity Label-MS Homo sapiens 34 SLU7   Co-fractionation Homo sapiens 35 NHLH2   Affinity Capture-MS Homo sapiens 36 GPR17 2840 Affinity Capture-MS Homo sapiens 37 LAMTOR1 55004 Proximity Label-MS Homo sapiens 38 VSIG4   Affinity Capture-MS Homo sapiens 39 BSG 682 Affinity Capture-MS Homo sapiens 40 GCGR   Affinity Capture-MS Homo sapiens 41 CTDP1 9150 Affinity Capture-MS Homo sapiens 42 P2RY8   Affinity Capture-MS Homo sapiens 43 RAB4A 5867 Proximity Label-MS Homo sapiens 44 MYH9 4627 Co-fractionation Homo sapiens 45 TRIM16 10626 Co-fractionation Homo sapiens 46 NTRK1 4914 Affinity Capture-MS Homo sapiens 47 PDIA3 2923 Co-fractionation Homo sapiens 48 GPR182   Affinity Capture-MS Homo sapiens 49 RAB2A 5862 Proximity Label-MS Homo sapiens 50 PEPD 5184 Co-fractionation Homo sapiens 51 ITFG3 83986 Affinity Capture-MS Homo sapiens 52 ELOVL5 60481 Proximity Label-MS Homo sapiens 53 SLC2A9   Affinity Capture-MS Homo sapiens 54 UPK2 7379 Affinity Capture-MS Homo sapiens 55 HNRNPDL 9987 Co-fractionation Homo sapiens 56 CD40 958 Affinity Capture-MS Homo sapiens 57 AIFM1 9131 Co-fractionation Homo sapiens 58 SIGLECL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 59 MSH2 4436 Affinity Capture-MS Homo sapiens 60 LRRC25   Affinity Capture-MS Homo sapiens 61 NPTN 27020 Affinity Capture-MS Homo sapiens 62 PRKAR2A 5576 Co-fractionation Homo sapiens 63 PRKAR1A 5573 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 64 MGARP   Affinity Capture-MS Homo sapiens 65 HSD3B7 80270 Proximity Label-MS Homo sapiens 66 NPY2R   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 EGFR 1956 Affinity Capture-MS Homo sapiens 68 PRKCI 5584 Co-fractionation Homo sapiens 69 PRMT5 10419 Co-fractionation Homo sapiens 70 RPA3 6119 Proximity Label-MS Homo sapiens 71 GPR45   Affinity Capture-MS Homo sapiens 72 RAB9A 9367 Proximity Label-MS Homo sapiens 73 CD244 51744 Affinity Capture-MS Homo sapiens 74 PGAM1 5223 Cross-Linking-MS (XL-MS) Homo sapiens 75 MSN 4478 Co-fractionation Homo sapiens 76 DNAJC13 23317 Affinity Capture-MS Homo sapiens 77 DENND6A 201627 Proximity Label-MS Homo sapiens 78 TMEM87A 25963 Affinity Capture-MS Homo sapiens 79 MYCBP 26292 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 81 PRKCSH 5589 Co-fractionation Homo sapiens 82 ALDH3A2 224 Affinity Capture-MS Homo sapiens 83 TMEM9 252839 Affinity Capture-MS Homo sapiens 84 HLA-DMB 3109 Affinity Capture-MS Homo sapiens 85 OPALIN   Affinity Capture-MS Homo sapiens 86 MFSD4   Affinity Capture-MS Homo sapiens 87 OSTM1 28962 Affinity Capture-MS Homo sapiens 88 CLEC2D   Affinity Capture-MS Homo sapiens 89 MEN1 4221 Affinity Capture-MS Homo sapiens 90 DPY30 84661 Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens 91 EFNB1 1947 Affinity Capture-MS Homo sapiens 92 NHLRC2 374354 Affinity Capture-MS Homo sapiens 93 SLAMF1 6504 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 94 GZMH   Affinity Capture-MS Homo sapiens 95 TCL1B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 96 NCL 4691 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 97 RAB7A 7879 Proximity Label-MS Homo sapiens 98 RAB11A 8766 Proximity Label-MS Homo sapiens 99 ORAI1 84876 Affinity Capture-MS Homo sapiens 100 FXYD3 5349 Affinity Capture-MS Homo sapiens 101 PSMC4 5704 Co-fractionation Homo sapiens 102 SPINT2 10653 Affinity Capture-MS Homo sapiens 103 FKBP2 2286 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 104 CSGALNACT1 55790 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 105 ADGRG2 10149 Affinity Capture-MS Homo sapiens 106 TATDN3   Affinity Capture-MS Homo sapiens View the network

Pathways in which ARFGEF1 is involved

No pathways found