Gene description for UQCRC2
Gene name ubiquinol-cytochrome c reductase core protein II
Gene symbol UQCRC2
Other names/aliases MC3DN5
QCR2
UQCR2
Species Homo sapiens
 Database cross references - UQCRC2
ExoCarta ExoCarta_7385
Vesiclepedia VP_7385
Entrez Gene 7385
HGNC 12586
MIM 191329
UniProt P22695  
 UQCRC2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 17956143    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for UQCRC2
Molecular Function
    metalloendopeptidase activity GO:0004222 IEA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    oxidative phosphorylation GO:0006119 TAS
    mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 NAS
    proteolysis GO:0006508 IEA
    aerobic respiration GO:0009060 TAS
    cellular respiration GO:0045333 NAS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 TAS
    respiratory chain complex III GO:0045275 IDA
 Experiment description of studies that identified UQCRC2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for UQCRC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RPSA 3921
Co-fractionation Homo sapiens
2 COX5A 9377
Co-fractionation Homo sapiens
3 ATP6V1B2 526
Co-fractionation Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 AFG3L2 10939
Co-fractionation Homo sapiens
6 EMC2 9694
Co-fractionation Homo sapiens
7 POR 5447
Co-fractionation Homo sapiens
8 SPRTN  
Affinity Capture-MS Homo sapiens
9 CCT3 7203
Co-fractionation Homo sapiens
10 RAB1A 5861
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
11 ATP6V1A 523
Co-fractionation Homo sapiens
12 VAPA 9218
Co-fractionation Homo sapiens
13 SSR2  
Co-fractionation Homo sapiens
14 SKI 6497
Affinity Capture-MS Homo sapiens
15 MTX1 4580
Co-fractionation Homo sapiens
16 TPP1 1200
Co-fractionation Homo sapiens
17 TPM2 7169
Co-fractionation Homo sapiens
18 RPA2 6118
Proximity Label-MS Homo sapiens
19 LAP3 51056
Affinity Capture-MS Homo sapiens
20 ADRB2  
Affinity Capture-MS Homo sapiens
21 ALDH2 217
Co-fractionation Homo sapiens
22 NDUFB5 4711
Co-fractionation Homo sapiens
23 ARMCX3 51566
Co-fractionation Homo sapiens
24 APOE 348
Co-fractionation Homo sapiens
25 MRPL37 51253
Co-fractionation Homo sapiens
26 UQCRB 7381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
27 HSP90AB1 3326
Co-fractionation Homo sapiens
28 NDUFS7 374291
Co-fractionation Homo sapiens
29 CCT6B 10693
Co-fractionation Homo sapiens
30 UQCR10 29796
Affinity Capture-MS Homo sapiens
31 NDUFA4 4697
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
32 Csk 12988
Affinity Capture-MS Mus musculus
33 ASXL1  
Affinity Capture-MS Homo sapiens
34 HSD17B12 51144
Co-fractionation Homo sapiens
35 NDUFS2 4720
Co-fractionation Homo sapiens
36 APP 351
Co-fractionation Homo sapiens
37 SLC25A24 29957
Co-fractionation Homo sapiens
38 TOMM22 56993
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
39 LRPPRC 10128
Co-fractionation Homo sapiens
40 CTSD 1509
Co-fractionation Homo sapiens
41 C9orf78 51759
Affinity Capture-MS Homo sapiens
42 NDUFB9 4715
Co-fractionation Homo sapiens
43 MGST1 4257
Co-fractionation Homo sapiens
44 COIL  
Proximity Label-MS Homo sapiens
45 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
46 B3GNT2 10678
Affinity Capture-MS Homo sapiens
47 OGDH 4967
Co-fractionation Homo sapiens
48 PRDX3 10935
Co-fractionation Homo sapiens
49 PC 5091
Co-fractionation Homo sapiens
50 NDUFB8 4714
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
51 COQ9  
Affinity Capture-MS Homo sapiens
52 SDHB 6390
Co-fractionation Homo sapiens
53 COX7A2L 9167
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
54 PTPMT1 114971
Affinity Capture-MS Homo sapiens
55 CYB5R1 51706
Co-fractionation Homo sapiens
56 RCN2 5955
Co-fractionation Homo sapiens
57 FBXW7  
Affinity Capture-MS Homo sapiens
58 PRC1 9055
Affinity Capture-MS Homo sapiens
59 NDUFA5 4698
Co-fractionation Homo sapiens
60 COA3 28958
Co-fractionation Homo sapiens
61 COX7A2 1347
Co-fractionation Homo sapiens
62 ETFA 2108
Co-fractionation Homo sapiens
63 SSR1 6745
Co-fractionation Homo sapiens
64 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 ATP2A2 488
Co-fractionation Homo sapiens
66 DDOST 1650
Co-fractionation Homo sapiens
67 MYCN  
Affinity Capture-MS Homo sapiens
68 RAB5B 5869
Co-fractionation Homo sapiens
69 ATP5O 539
Co-fractionation Homo sapiens
70 ATP5C1 509
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
71 VAPB 9217
Co-fractionation Homo sapiens
72 C20orf24  
Co-fractionation Homo sapiens
73 LACTB 114294
Co-fractionation Homo sapiens
74 NDUFV1 4723
Co-fractionation Homo sapiens
75 PHB 5245
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
76 CLTC 1213
Co-fractionation Homo sapiens
77 SCD5  
Co-fractionation Homo sapiens
78 IDH3A 3419
Co-fractionation Homo sapiens
79 MECP2 4204
Affinity Capture-MS Homo sapiens
80 RAB35 11021
Proximity Label-MS Homo sapiens
81 ANKRD34C  
Co-fractionation Homo sapiens
82 SSR3 6747
Co-fractionation Homo sapiens
83 CYTB 4519
Affinity Capture-MS Homo sapiens
84 FAF2 23197
Affinity Capture-MS Homo sapiens
85 HK1 3098
Co-fractionation Homo sapiens
86 UQCRQ 27089
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
87 NDUFS5 4725
Co-fractionation Homo sapiens
88 FANCD2  
Affinity Capture-MS Homo sapiens
89 NDUFB10 4716
Co-fractionation Homo sapiens
90 SFXN1 94081
Co-fractionation Homo sapiens
91 RAB1B 81876
Co-fractionation Homo sapiens
92 LMAN1 3998
Co-fractionation Homo sapiens
93 INSIG2  
Affinity Capture-MS Homo sapiens
94 KLF16  
Affinity Capture-MS Homo sapiens
95 NNT 23530
Co-fractionation Homo sapiens
96 FKBP10 60681
Co-fractionation Homo sapiens
97 PPM1E  
Affinity Capture-MS Homo sapiens
98 COPB1 1315
Co-fractionation Homo sapiens
99 DLD 1738
Co-fractionation Homo sapiens
100 NDUFA9 4704
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
101 MTCH2 23788
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
102 P4HA1 5033
Co-fractionation Homo sapiens
103 NDUFS4 4724
Co-fractionation Homo sapiens
104 COX15 1355
Affinity Capture-MS Homo sapiens
105 NDUFB7 4713
Co-fractionation Homo sapiens
106 PARK2  
Affinity Capture-MS Homo sapiens
107 Ddb1 13194
Affinity Capture-MS Mus musculus
108 PRKCSH 5589
Co-fractionation Homo sapiens
109 STOM 2040
Affinity Capture-MS Homo sapiens
110 HSP90B1 7184
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
111 NDUFA8 4702
Co-fractionation Homo sapiens
112 PSMC1 5700
Co-fractionation Homo sapiens
113 TUFM 7284
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
114 ATF2  
Affinity Capture-MS Homo sapiens
115 KPNA4 3840
Co-fractionation Homo sapiens
116 CIAO1 9391
Affinity Capture-MS Homo sapiens
117 UBR5 51366
Co-fractionation Homo sapiens
118 RAP1B 5908
Co-fractionation Homo sapiens
119 PHB2 11331
Co-fractionation Homo sapiens
120 VCP 7415
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
121 NTRK1 4914
Affinity Capture-MS Homo sapiens
122 ACADM 34
Co-fractionation Homo sapiens
123 RAP1A 5906
Co-fractionation Homo sapiens
124 PON2 5445
Co-fractionation Homo sapiens
125 CCDC8  
Affinity Capture-MS Homo sapiens
126 CYC1 1537
Co-fractionation Homo sapiens
127 UQCRC1 7384
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
128 RPN1 6184
Co-fractionation Homo sapiens
129 GANAB 23193
Co-fractionation Homo sapiens
130 TECR 9524
Co-fractionation Homo sapiens
131 RAB10 10890
Co-fractionation Homo sapiens
132 MCCC1 56922
Affinity Capture-MS Homo sapiens
133 AGPS 8540
Co-fractionation Homo sapiens
134 HNRNPA3 220988
Co-fractionation Homo sapiens
135 HDAC5 10014
Affinity Capture-MS Homo sapiens
136 VDAC2 7417
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
137 CYP27A1  
Co-fractionation Homo sapiens
138 ATP5B 506
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
139 COX4I1 1327
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
140 KDF1  
Affinity Capture-MS Homo sapiens
141 SSR4 6748
Co-fractionation Homo sapiens
142 SQRDL 58472
Co-fractionation Homo sapiens
143 ZNF326 284695
Co-fractionation Homo sapiens
144 CISD3 284106
Affinity Capture-MS Homo sapiens
145 NDUFA12 55967
Co-fractionation Homo sapiens
146 C15orf48  
Affinity Capture-MS Homo sapiens
147 SFPQ 6421
Co-fractionation Homo sapiens
148 CACNA1A  
Two-hybrid Homo sapiens
149 IPO5 3843
Co-fractionation Homo sapiens
150 HADHB 3032
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
151 HADHA 3030
Co-fractionation Homo sapiens
152 RPN2 6185
Co-fractionation Homo sapiens
153 CANX 821
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
154 KCND3 3752
Affinity Capture-Western Homo sapiens
155 BCKDHB 594
Co-fractionation Homo sapiens
156 EMC8 10328
Co-fractionation Homo sapiens
157 RAB5A 5868
Co-fractionation Homo sapiens
158 SDHA 6389
Affinity Capture-MS Homo sapiens
159 PCCB 5096
Co-fractionation Homo sapiens
160 SIRT7  
Affinity Capture-MS Homo sapiens
161 CCT6A 908
Co-fractionation Homo sapiens
162 ATP5A1 498
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
163 HMOX2 3163
Co-fractionation Homo sapiens
164 EEF2 1938
Co-fractionation Homo sapiens
165 GOLT1B 51026
Affinity Capture-MS Homo sapiens
166 Rmdn3  
Affinity Capture-MS Mus musculus
167 LAMTOR2 28956
Co-fractionation Homo sapiens
168 CUL3 8452
Affinity Capture-MS Homo sapiens
169 SLX1B  
Affinity Capture-MS Homo sapiens
170 LONP1 9361
Co-fractionation Homo sapiens
171 SRSF5 6430
Co-fractionation Homo sapiens
172 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
173 FKBP8 23770
Co-fractionation Homo sapiens
174 CPT1A 1374
Co-fractionation Homo sapiens
175 ARF6 382
Proximity Label-MS Homo sapiens
176 FBXO6 26270
Affinity Capture-MS Homo sapiens
177 COX6B1 1340
Affinity Capture-MS Homo sapiens
178 DNAJB14  
Affinity Capture-MS Homo sapiens
179 RAB6B 51560
Co-fractionation Homo sapiens
180 RIPK4  
Affinity Capture-MS Homo sapiens
181 CDC42 998
Co-fractionation Homo sapiens
182 ZNF782  
Co-fractionation Homo sapiens
183 PMPCB 9512
Proximity Label-MS Homo sapiens
184 SOAT1 6646
Affinity Capture-MS Homo sapiens
185 TOMM6  
Co-fractionation Homo sapiens
186 DKC1 1736
Co-fractionation Homo sapiens
187 PPP2R1A 5518
Co-fractionation Homo sapiens
188 RPA3 6119
Proximity Label-MS Homo sapiens
189 PINK1  
Affinity Capture-MS Homo sapiens
190 TMCO1 54499
Co-fractionation Homo sapiens
191 P4HB 5034
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
192 DLST 1743
Affinity Capture-MS Homo sapiens
193 ASPH 444
Co-fractionation Homo sapiens
194 PSMC5 5705
Co-fractionation Homo sapiens
195 ACTB 60
Co-fractionation Homo sapiens
196 DUSP21  
Affinity Capture-MS Homo sapiens
197 CYB5R3 1727
Co-fractionation Homo sapiens
198 RHOB 388
Proximity Label-MS Homo sapiens
199 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
200 ANK3  
Proximity Label-MS Homo sapiens
201 COX2 4513
Co-fractionation Homo sapiens
202 HSPD1 3329
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
203 TOMM5  
Co-fractionation Homo sapiens
204 COX7C 1350
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
205 PEX3 8504
Proximity Label-MS Homo sapiens
206 NFATC2  
Affinity Capture-MS Homo sapiens
207 RTN4 57142
Affinity Capture-Western Homo sapiens
208 NDUFS1 4719
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
209 SCCPDH 51097
Co-fractionation Homo sapiens
210 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 CALR 811
Co-fractionation Homo sapiens
212 TPM3 7170
Co-fractionation Homo sapiens
213 IMMT 10989
Co-fractionation Homo sapiens
214 SNCA 6622
Affinity Capture-Western Homo sapiens
215 GLS 2744
Co-fractionation Homo sapiens
216 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
217 PSMB10 5699
Affinity Capture-MS Homo sapiens
218 CCT8 10694
Co-fractionation Homo sapiens
219 Ercc6l  
Affinity Capture-MS Mus musculus
220 C11orf52 91894
Proximity Label-MS Homo sapiens
221 ATP5J 522
Co-fractionation Homo sapiens
222 EHD4 30844
Co-fractionation Homo sapiens
223 EMC4 51234
Co-fractionation Homo sapiens
224 ICT1 3396
Affinity Capture-MS Homo sapiens
225 CS 1431
Proximity Label-MS Homo sapiens
226 UQCRH 7388
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
227 ZNF746  
Affinity Capture-MS Homo sapiens
228 ALDH1B1 219
Co-fractionation Homo sapiens
229 PDHA1 5160
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
230 DDX39B 7919
Co-fractionation Homo sapiens
231 HNRNPM 4670
Co-fractionation Homo sapiens
232 LRRC59 55379
Co-fractionation Homo sapiens
233 SQSTM1 8878
Proximity Label-MS Homo sapiens
234 SCD 6319
Co-fractionation Homo sapiens
235 Htt  
Affinity Capture-MS Mus musculus
236 PDHB 5162
Co-fractionation Homo sapiens
237 HSP90AA1 3320
Co-fractionation Homo sapiens
238 SLAMF1 6504
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 MYL12A 10627
Co-fractionation Homo sapiens
240 HNRNPK 3190
Co-fractionation Homo sapiens
241 CCT7 10574
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
242 ATAD3A 55210
Co-fractionation Homo sapiens
243 UFL1 23376
Affinity Capture-MS Homo sapiens
244 IDE 3416
Co-fractionation Homo sapiens
245 KIAA1429 25962
Affinity Capture-MS Homo sapiens
246 NIPSNAP1 8508
Co-fractionation Homo sapiens
247 NDUFS8 4728
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
248 NCL 4691
Co-fractionation Homo sapiens
249 PTGES2 80142
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
250 CAD 790
Co-fractionation Homo sapiens
251 AIMP2 7965
Affinity Capture-MS Homo sapiens
252 RAB7A 7879
Co-fractionation Homo sapiens
253 ATP1A1 476
Co-fractionation Homo sapiens
254 TCF3  
Affinity Capture-MS Homo sapiens
255 C1QBP 708
Co-fractionation Homo sapiens
256 SERBP1 26135
Affinity Capture-MS Homo sapiens
257 KRAS 3845
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
258 RAB5C 5878
Co-fractionation Homo sapiens
259 C9orf72  
Affinity Capture-MS Homo sapiens
260 VDAC3 7419
Co-fractionation Homo sapiens
261 SEC61A1 29927
Co-fractionation Homo sapiens
262 CORO1C 23603
Co-fractionation Homo sapiens
263 BCKDHA 593
Co-fractionation Homo sapiens
264 DDRGK1 65992
Affinity Capture-MS Homo sapiens
265 MGST3 4259
Co-fractionation Homo sapiens
266 RANBP2 5903
Co-fractionation Homo sapiens
267 EP300 2033
Affinity Capture-MS Homo sapiens
268 TCP1 6950
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here