Gene description for HLA-C
Gene name major histocompatibility complex, class I, C
Gene symbol HLA-C
Other names/aliases D6S204
HLA-JY3
HLC-C
PSORS1
Species Homo sapiens
 Database cross references - HLA-C
ExoCarta ExoCarta_3107
Vesiclepedia VP_3107
Entrez Gene 3107
HGNC 4933
MIM 142840
UniProt P10321  
 HLA-C identified in exosomes derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 19837982    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Malignant pleural effusions 14975938    
Malignant pleural effusions 14975938    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Nasopharyngeal carcinoma cells 25857718    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Squamous carcinoma cells 20124223    
Urine 19056867    
 Gene ontology annotations for HLA-C
Molecular Function
    signaling receptor binding GO:0005102 IBA
    protein binding GO:0005515 IPI
    peptide antigen binding GO:0042605 IBA
    peptide antigen binding GO:0042605 IDA
    TAP binding GO:0046977 IDA
Biological Process
    positive regulation of T cell mediated cytotoxicity GO:0001916 IBA
    adaptive immune response GO:0002250 IEA
    antigen processing and presentation of endogenous peptide antigen via MHC class Ib GO:0002476 IBA
    antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent GO:0002486 IBA
    antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent GO:0002486 IDA
    immune response GO:0006955 IBA
    immune response GO:0006955 NAS
    innate immune response GO:0045087 IEA
Subcellular Localization
    Golgi membrane GO:0000139 TAS
    extracellular space GO:0005615 IBA
    endoplasmic reticulum GO:0005783 IDA
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 NAS
    plasma membrane GO:0005886 TAS
    external side of plasma membrane GO:0009897 IBA
    cell surface GO:0009986 IDA
    ER to Golgi transport vesicle membrane GO:0012507 TAS
    membrane GO:0016020 HDA
    secretory granule membrane GO:0030667 TAS
    phagocytic vesicle membrane GO:0030670 TAS
    early endosome membrane GO:0031901 TAS
    MHC class I protein complex GO:0042612 IDA
    recycling endosome membrane GO:0055038 TAS
    extracellular exosome GO:0070062 HDA
    lumenal side of endoplasmic reticulum membrane GO:0098553 TAS
 Experiment description of studies that identified HLA-C in exosomes
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
5
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
12
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
13
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 52
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 14975938    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes isolated from human malignant pleural effusions.
Authors "Bard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN"
Journal name AJRCMB
Publication year 2004
Sample Malignant pleural effusions
Sample name Pleural Fluid - Lung cancer
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
20
Experiment ID 53
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 14975938    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes isolated from human malignant pleural effusions.
Authors "Bard MP, Hegmans JP, Hemmes A, Luider TM, Willemsen R, Severijnen LA, van Meerbeeck JP, Burgers SA, Hoogsteden HC, Lambrecht BN"
Journal name AJRCMB
Publication year 2004
Sample Malignant pleural effusions
Sample name Pleural Fluid - Mesothelioma
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
21
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
25
Experiment ID 219
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name C666-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 220
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP69
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 221
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25857718    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins
Authors "Chan YK, Zhang H, Liu P, Tsao GS, Li Lung M, Mak NK, Ngok-Shun Wong R, Ying-Kit Yue P"
Journal name Int J Cancer
Publication year 2015
Sample Nasopharyngeal carcinoma cells
Sample name NP460
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.17-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
29
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for HLA-C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 RNF149 284996
Affinity Capture-MS Homo sapiens
2 DCBLD2 131566
Affinity Capture-MS Homo sapiens
3 INTS4  
Affinity Capture-MS Homo sapiens
4 HMOX1 3162
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 AHCTF1 25909
Affinity Capture-MS Homo sapiens
6 GJD3  
Proximity Label-MS Homo sapiens
7 EPHX4 253152
Affinity Capture-MS Homo sapiens
8 PISD  
Affinity Capture-MS Homo sapiens
9 QSOX1 5768
Affinity Capture-MS Homo sapiens
10 DNAJC11 55735
Affinity Capture-MS Homo sapiens
11 SLC22A8 9376
Affinity Capture-MS Homo sapiens
12 PON2 5445
Affinity Capture-MS Homo sapiens
13 KLK8 11202
Affinity Capture-MS Homo sapiens
14 GPX8 493869
Affinity Capture-MS Homo sapiens
15 C1orf27 54953
Affinity Capture-MS Homo sapiens
16 TCTN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 CD3D 915
Affinity Capture-MS Homo sapiens
18 MARCKS 4082
Proximity Label-MS Homo sapiens
19 GALNT1 2589
Affinity Capture-MS Homo sapiens
20 HLA-E 3133
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 HLA-F 3134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 C3orf58 205428
Affinity Capture-MS Homo sapiens
23 ATP1B1 481
Affinity Capture-MS Homo sapiens
24 MON2 23041
Affinity Capture-MS Homo sapiens
25 TM9SF2 9375
Affinity Capture-MS Homo sapiens
26 LPHN1  
Affinity Capture-MS Homo sapiens
27 ADRB2  
Affinity Capture-MS Homo sapiens
28 TMEM206 55248
Affinity Capture-MS Homo sapiens
29 TUBB8 347688
Affinity Capture-MS Homo sapiens
30 PRRG4  
Two-hybrid Homo sapiens
31 BSCL2  
Affinity Capture-MS Homo sapiens
32 ST8SIA4 7903
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 HSD17B11 51170
Proximity Label-MS Homo sapiens
34 UBC 7316
Affinity Capture-MS Homo sapiens
35 FANCI 55215
Affinity Capture-MS Homo sapiens
36 DNAJC25 548645
Proximity Label-MS Homo sapiens
37 TMEM67 91147
Affinity Capture-MS Homo sapiens
38 STX4 6810
Proximity Label-MS Homo sapiens
39 HSD17B12 51144
Affinity Capture-MS Homo sapiens
40 CPT1A 1374
Affinity Capture-MS Homo sapiens
41 PI4KA 5297
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 SLC39A3  
Affinity Capture-MS Homo sapiens
43 TGFBR1 7046
Affinity Capture-MS Homo sapiens
44 KIAA1429 25962
Affinity Capture-MS Homo sapiens
45 NETO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 B3GAT1  
Proximity Label-MS Homo sapiens
47 DTX2 113878
Proximity Label-MS Homo sapiens
48 B3GNT2 10678
Affinity Capture-MS Homo sapiens
49 HLA-DRB3 3125
Affinity Capture-MS Homo sapiens
50 KIF23 9493
Affinity Capture-MS Homo sapiens
51 PCK1 5105
Affinity Capture-MS Homo sapiens
52 HLA-B 3106
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 ASIC1  
Affinity Capture-MS Homo sapiens
54 RNASE4 6038
Affinity Capture-MS Homo sapiens
55 LILRB1  
Reconstituted Complex Homo sapiens
56 FBXW7  
Affinity Capture-MS Homo sapiens
57 ACSL4 2182
Affinity Capture-MS Homo sapiens
58 CLEC2B  
Affinity Capture-MS Homo sapiens
59 HLA-H 3136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 LGR4 55366
Affinity Capture-MS Homo sapiens
61 ADGRG6 57211
Affinity Capture-MS Homo sapiens
62 NCR3  
Affinity Capture-MS Homo sapiens
63 SSR1 6745
Proximity Label-MS Homo sapiens
64 MAD2L2 10459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 ABCA2 20
Affinity Capture-MS Homo sapiens
66 NUS1  
Affinity Capture-MS Homo sapiens
67 GAL3ST2  
Affinity Capture-MS Homo sapiens
68 SCARB1 949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 NLGN2 57555
Affinity Capture-MS Homo sapiens
70 DNAJC16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 NCAPG2 54892
Affinity Capture-MS Homo sapiens
72 LIPG 9388
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 UFSP2 55325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 BTAF1 9044
Affinity Capture-MS Homo sapiens
75 RAB3B 5865
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 PRTN3 5657
Affinity Capture-MS Homo sapiens
77 KIR2DL3  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
78 ARFGEF2 10564
Affinity Capture-MS Homo sapiens
79 TSHB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 ST6GALNAC3  
Affinity Capture-MS Homo sapiens
81 FAF2 23197
Affinity Capture-MS Homo sapiens
82 EBAG9 9166
Proximity Label-MS Homo sapiens
83 BATF2  
Two-hybrid Homo sapiens
84 FAM20C 56975
Affinity Capture-MS Homo sapiens
85 NTSR1  
Affinity Capture-MS Homo sapiens
86 FANCD2  
Affinity Capture-MS Homo sapiens
87 METTL7A 25840
Proximity Label-MS Homo sapiens
88 HLA-G 3135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 FASTKD1  
Affinity Capture-MS Homo sapiens
90 ATP1A3 478
Affinity Capture-MS Homo sapiens
91 TMEM63B 55362
Affinity Capture-MS Homo sapiens
92 TMEM106C 79022
Affinity Capture-MS Homo sapiens
93 GPR50  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 KIAA1715 80856
Proximity Label-MS Homo sapiens
95 PXMP2  
Proximity Label-MS Homo sapiens
96 E2F4  
Affinity Capture-MS Homo sapiens
97 LRRC59 55379
Proximity Label-MS Homo sapiens
98 ZDHHC3 51304
Affinity Capture-MS Homo sapiens
99 FAM213A 84293
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 YBX1 4904
Two-hybrid Homo sapiens
101 CLPTM1L 81037
Affinity Capture-MS Homo sapiens
102 CNNM1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 POMGNT1 55624
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 TMED6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 FAM3C 10447
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 CHST14 113189
Affinity Capture-MS Homo sapiens
107 RNF213 57674
Affinity Capture-MS Homo sapiens
108 ADPGK 83440
Affinity Capture-MS Homo sapiens
109 ITGA6 3655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 RB1CC1 9821
Affinity Capture-MS Homo sapiens
111 CNNM3 26505
Affinity Capture-MS Homo sapiens
112 CEACAM21  
Affinity Capture-MS Homo sapiens
113 MTX1 4580
Affinity Capture-MS Homo sapiens
114 SCAP  
Affinity Capture-MS Homo sapiens
115 TARS2 80222
Affinity Capture-MS Homo sapiens
116 TUBA1A 7846
Affinity Capture-MS Homo sapiens
117 MCAM 4162
Proximity Label-MS Homo sapiens
118 DNAJB8  
Affinity Capture-MS Homo sapiens
119 CD8A 925
Reconstituted Complex Homo sapiens
120 CDKAL1  
Affinity Capture-MS Homo sapiens
121 CDH1 999
Proximity Label-MS Homo sapiens
122 NCAPD3 23310
Affinity Capture-MS Homo sapiens
123 ST6GAL1 6480
Affinity Capture-MS Homo sapiens
124 PIGT 51604
Affinity Capture-MS Homo sapiens
125 EIF2AK3  
Affinity Capture-MS Homo sapiens
126 GPR182  
Two-hybrid Homo sapiens
127 ITM2C 81618
Affinity Capture-MS Homo sapiens
128 HLA-DRB5 3127
Affinity Capture-MS Homo sapiens
129 MCOLN3  
Affinity Capture-MS Homo sapiens
130 IL27RA 9466
Affinity Capture-MS Homo sapiens
131 NMU  
Affinity Capture-MS Homo sapiens
132 LYPD1  
Affinity Capture-MS Homo sapiens
133 Calml3  
Affinity Capture-MS Mus musculus
134 DHFRL1  
Proximity Label-MS Homo sapiens
135 UGT1A9  
Affinity Capture-MS Homo sapiens
136 ITFG1 81533
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 DNAJC12  
Affinity Capture-MS Homo sapiens
138 ELOVL5 60481
Proximity Label-MS Homo sapiens
139 HFE  
Affinity Capture-MS Homo sapiens
140 SEC61B 10952
Proximity Label-MS Homo sapiens
141 TAP2 6891
Affinity Capture-Western Homo sapiens
142 TXNDC11 51061
Affinity Capture-MS Homo sapiens
143 CHEK2  
Affinity Capture-MS Homo sapiens
144 UPK2 7379
Affinity Capture-MS Homo sapiens
145 HEATR6  
Affinity Capture-MS Homo sapiens
146 ANLN 54443
Affinity Capture-MS Homo sapiens
147 LMAN2L 81562
Affinity Capture-MS Homo sapiens
148 HTR3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 Ptpn2  
Affinity Capture-MS Mus musculus
150 Rab5c 19345
Affinity Capture-MS Mus musculus
151 HSPA5 3309
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
152 SGPL1 8879
Affinity Capture-MS Homo sapiens
153 LRFN3  
Affinity Capture-MS Homo sapiens
154 TMEM106B 54664
Affinity Capture-MS Homo sapiens
155 TMEM30A 55754
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 RPN2 6185
Proximity Label-MS Homo sapiens
157 AIFM1 9131
Affinity Capture-MS Homo sapiens
158 SORT1 6272
Affinity Capture-MS Homo sapiens
159 DNAJB12 54788
Affinity Capture-MS Homo sapiens
160 KIR2DL1  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
161 PPM1E  
Affinity Capture-MS Homo sapiens
162 ECT2 1894
Affinity Capture-MS Homo sapiens
163 GABRA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 TMEM223  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
165 HMOX2 3163
Affinity Capture-MS Homo sapiens
166 LAMP1 3916
Proximity Label-MS Homo sapiens
167 Bmpr1a  
Affinity Capture-MS Mus musculus
168 B3GNT3 10331
Affinity Capture-MS Homo sapiens
169 SLC30A9 10463
Affinity Capture-MS Homo sapiens
170 BCAP31 10134
Proximity Label-MS Homo sapiens
171 HSD3B7 80270
Proximity Label-MS Homo sapiens
172 CUL3 8452
Affinity Capture-MS Homo sapiens
173 ACAD10  
Affinity Capture-MS Homo sapiens
174 CLEC4A  
Affinity Capture-MS Homo sapiens
175 KLRD1  
Affinity Capture-MS Homo sapiens
176 GAA 2548
Affinity Capture-MS Homo sapiens
177 FBXO6 26270
Affinity Capture-MS Homo sapiens
178 ATP1B3 483
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
179 AQP3  
Affinity Capture-MS Homo sapiens
180 OPRL1 4987
Two-hybrid Homo sapiens
181 LRRC32 2615
Affinity Capture-MS Homo sapiens
182 IL5RA  
Affinity Capture-MS Homo sapiens
183 NPSR1  
Two-hybrid Homo sapiens
184 F3 2152
Affinity Capture-MS Homo sapiens
185 RPN1 6184
Proximity Label-MS Homo sapiens
186 TANK 10010
Two-hybrid Homo sapiens
187 AURKB 9212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 BTNL2  
Affinity Capture-MS Homo sapiens
189 MAPK6  
Affinity Capture-MS Homo sapiens
190 MTMR12 54545
Affinity Capture-MS Homo sapiens
191 UBE3C 9690
Affinity Capture-MS Homo sapiens
192 CNR2  
Affinity Capture-MS Homo sapiens
193 IL12RB1  
Affinity Capture-MS Homo sapiens
194 ATP2A1 487
Proximity Label-MS Homo sapiens
195 KLRG2 346689
Affinity Capture-MS Homo sapiens
196 A4GNT  
Affinity Capture-MS Homo sapiens
197 PSCA 8000
Affinity Capture-MS Homo sapiens
198 TMEM246 84302
Affinity Capture-MS Homo sapiens
199 MROH1 727957
Affinity Capture-MS Homo sapiens
200 AP1M2 10053
Affinity Capture-MS Homo sapiens
201 GALNT7 51809
Affinity Capture-MS Homo sapiens
202 DNAJC1 64215
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 PVR 5817
Affinity Capture-MS Homo sapiens
204 SLC18A1  
Affinity Capture-MS Homo sapiens
205 DNASE1L1 1774
Affinity Capture-MS Homo sapiens
206 RHOB 388
Proximity Label-MS Homo sapiens
207 HLA-DQB1 3119
Affinity Capture-MS Homo sapiens
208 METTL9 51108
Affinity Capture-MS Homo sapiens
209 GPR37  
Two-hybrid Homo sapiens
210 STX10 8677
Affinity Capture-MS Homo sapiens
211 KIR2DL2  
Co-crystal Structure Homo sapiens
212 HEATR1 55127
Affinity Capture-MS Homo sapiens
213 MTM1 4534
Affinity Capture-MS Homo sapiens
214 TMEM59 9528
Affinity Capture-MS Homo sapiens
215 LRRC8E 80131
Affinity Capture-MS Homo sapiens
216 DOCK3  
Affinity Capture-MS Homo sapiens
217 CCDC8  
Affinity Capture-MS Homo sapiens
218 LOC100507703  
Affinity Capture-MS Homo sapiens
219 NRG1 3084
Affinity Capture-MS Homo sapiens
220 SLC39A6 25800
Affinity Capture-MS Homo sapiens
221 ADAM30 11085
Affinity Capture-MS Homo sapiens
222 CDC25A  
Two-hybrid Homo sapiens
223 INS 3630
Affinity Capture-MS Homo sapiens
224 MR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 ARV1  
Affinity Capture-MS Homo sapiens
226 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
227 NAAA  
Affinity Capture-MS Homo sapiens
228 KIF14 9928
Affinity Capture-MS Homo sapiens
229 HLA-DRB1 3123
Affinity Capture-MS Homo sapiens
230 RHOBTB3 22836
Affinity Capture-MS Homo sapiens
231 IGHD  
Affinity Capture-MS Homo sapiens
232 VTI1A 143187
Affinity Capture-MS Homo sapiens
233 PDIA4 9601
Proximity Label-MS Homo sapiens
234 NEK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 ADAM33 80332
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 ASIC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
237 TNFSF14  
Affinity Capture-MS Homo sapiens
238 CD1B 910
Affinity Capture-MS Homo sapiens
239 WNT4  
Affinity Capture-MS Homo sapiens
240 CD1A 909
Affinity Capture-MS Homo sapiens
241 TNFSF9  
Affinity Capture-MS Homo sapiens
242 HLA-A 3105
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
243 NSDHL 50814
Affinity Capture-MS Homo sapiens
244 CLEC4E  
Affinity Capture-MS Homo sapiens
245 ERGIC1 57222
Proximity Label-MS Homo sapiens
246 DDX58 23586
Affinity Capture-RNA Homo sapiens
247 PTPRO 5800
Affinity Capture-MS Homo sapiens
248 STARD3 10948
Affinity Capture-MS Homo sapiens
249 ROR2 4920
Affinity Capture-MS Homo sapiens
250 Tgfbr1 21812
Affinity Capture-MS Mus musculus
251 Tuba3a 22144
Affinity Capture-MS Mus musculus
252 TLR9  
Affinity Capture-MS Homo sapiens
253 KIR3DL3  
Affinity Capture-MS Homo sapiens
254 KIR2DS2  
Reconstituted Complex Homo sapiens
255 OGFOD3 79701
Affinity Capture-MS Homo sapiens
256 LMF1 64788
Affinity Capture-MS Homo sapiens
257 TAPBP 6892
Affinity Capture-MS Homo sapiens
258 HLA-DQA1 3117
Affinity Capture-MS Homo sapiens
259 BRICD5  
Affinity Capture-MS Homo sapiens
260 EXT2 2132
Affinity Capture-MS Homo sapiens
261 CLSTN3 9746
Affinity Capture-MS Homo sapiens
262 SEC62 7095
Proximity Label-MS Homo sapiens
263 L2HGDH  
Affinity Capture-MS Homo sapiens
264 RAB7A 7879
Proximity Label-MS Homo sapiens
265 B2M 567
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 CIT 11113
Affinity Capture-MS Homo sapiens
267 EPHA2 1969
Proximity Label-MS Homo sapiens
268 ST14 6768
Affinity Capture-MS Homo sapiens
269 CISD2 493856
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 CUL7 9820
Affinity Capture-MS Homo sapiens
271 KRAS 3845
Proximity Label-MS Homo sapiens
272 RAB5C 5878
Proximity Label-MS Homo sapiens
273 C9orf72  
Affinity Capture-MS Homo sapiens
274 LILRB2  
Reconstituted Complex Homo sapiens
275 TMEM132A 54972
Affinity Capture-MS Homo sapiens
276 CKAP4 10970
Proximity Label-MS Homo sapiens
277 HLA-C 3107
FRET Homo sapiens
FRET Homo sapiens
278 ANKRD46 157567
Affinity Capture-MS Homo sapiens
279 PTCH1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
280 CAV1 857
Proximity Label-MS Homo sapiens
281 KIAA0922  
Affinity Capture-MS Homo sapiens
282 CALR3  
Proximity Label-MS Homo sapiens
283 ITM2B 9445
Affinity Capture-MS Homo sapiens
284 DERL1 79139
Proximity Label-MS Homo sapiens
285 RNF139  
Affinity Capture-Western Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here