Gene description for AURKB
Gene name	aurora kinase B
Gene symbol	AURKB
Other names/aliases	AIK2 AIM-1 AIM1 ARK2 AurB IPL1 PPP1R48 STK12 STK5 aurkb-sv1 aurkb-sv2
Species	Homo sapiens
Database cross references - AURKB
ExoCarta	ExoCarta_9212
Vesiclepedia	VP_9212
Entrez Gene	9212
HGNC	11390
MIM	604970
UniProt	Q96GD4
AURKB identified in sEVs derived from the following tissue/cell type
Gastric cancer cells	33991177
Gastric cancer cells	33991177
Gastric cancer cells	33991177

Gene ontology annotations for AURKB

Molecular Function     protein serine/threonine kinase activity GO:0004674 EXP     protein serine/threonine kinase activity GO:0004674 IDA     protein serine/threonine kinase activity GO:0004674 IDA     protein serine/threonine kinase activity GO:0004674 TAS     protein serine/threonine/tyrosine kinase activity GO:0004712 TAS     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     kinase binding GO:0019900 IPI     protein serine kinase activity GO:0106310 IEA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     mitotic cell cycle GO:0000278 NAS     mitotic cytokinesis GO:0000281 NAS     negative regulation of B cell apoptotic process GO:0002903 IDA     spindle organization GO:0007051 IMP     mitotic spindle organization GO:0007052 IBA     positive regulation of microtubule depolymerization GO:0031117 IDA     positive regulation of telomere maintenance GO:0032206 IMP     regulation of cytokinesis GO:0032465 IBA     negative regulation of cytokinesis GO:0032466 ISS     positive regulation of cytokinesis GO:0032467 IMP     positive regulation of cytokinesis GO:0032467 TAS     protein localization to kinetochore GO:0034501 IMP     cellular response to UV GO:0034644 IDA     cleavage furrow formation GO:0036089 IDA     post-translational protein modification GO:0043687 ISS     cell cycle G2/M phase transition GO:0044839 IDA     mitotic cytokinesis checkpoint signaling GO:0044878 ISS     negative regulation of innate immune response GO:0045824 IDA     mitotic spindle midzone assembly GO:0051256 IMP     mitotic spindle midzone assembly GO:0051256 NAS     mitotic spindle midzone assembly GO:0051256 TAS     regulation of chromosome segregation GO:0051983 TAS     midbody abscission GO:0061952 ISS     positive regulation of mitotic sister chromatid segregation GO:0062033 IDA     positive regulation of mitotic cell cycle spindle assembly checkpoint GO:0090267 NAS     mitotic spindle assembly GO:0090307 NAS     repair of mitotic kinetochore microtubule attachment defect GO:0140273 IDA     negative regulation of cGAS/STING signaling pathway GO:0160049 IDA     regulation of signal transduction by p53 class mediator GO:1901796 TAS     positive regulation of mitotic sister chromatid separation GO:1901970 NAS     positive regulation of attachment of mitotic spindle microtubules to kinetochore GO:1902425 NAS     positive regulation of mitotic cytokinesis GO:1903490 NAS     positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore GO:1905116 IDA     mitotic sister chromatid biorientation GO:1990758 IDA Subcellular Localization     kinetochore GO:0000776 IBA     kinetochore GO:0000776 IDA     kinetochore GO:0000776 IDA     condensed chromosome, centromeric region GO:0000779 IDA     spindle pole GO:0000922 IBA     nucleus GO:0005634 IBA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     centrosome GO:0005813 IBA     spindle GO:0005819 TAS     cytosol GO:0005829 TAS     spindle microtubule GO:0005876 IBA     chromocenter GO:0010369 IEA     microtubule cytoskeleton GO:0015630 IDA     midbody GO:0030496 IBA     midbody GO:0030496 IDA     midbody GO:0030496 TAS     chromosome passenger complex GO:0032133 IBA     chromosome passenger complex GO:0032133 IPI     chromosome passenger complex GO:0032133 TAS     spindle midzone GO:0051233 IBA     mitotic spindle pole GO:0097431 IEA     mitotic spindle midzone GO:1990023 IEA