Gene description for HIST1H3A
Gene name histone cluster 1, H3a
Gene symbol HIST1H3A
Other names/aliases H3/A
H3FA
Species Homo sapiens
 Database cross references - HIST1H3A
ExoCarta ExoCarta_8350
Vesiclepedia VP_8350
Entrez Gene 8350
HGNC 4766
MIM 602810
UniProt P68431  
 HIST1H3A identified in sEVs derived from the following tissue/cell type
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for HIST1H3A
Molecular Function
    DNA binding GO:0003677 IEA
    protein binding GO:0005515 IDA
    protein binding GO:0005515 IPI
    structural constituent of chromatin GO:0030527 IEA
    cadherin binding GO:0045296 HDA
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    chromatin organization GO:0006325 NAS
    nucleosome assembly GO:0006334 IDA
    nucleosome assembly GO:0006334 IMP
    gene expression GO:0010467 IDA
    telomere organization GO:0032200 TAS
    epigenetic regulation of gene expression GO:0040029 IDA
Subcellular Localization
    nucleosome GO:0000786 IDA
    nucleosome GO:0000786 IPI
    extracellular region GO:0005576 TAS
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    membrane GO:0016020 HDA
    protein-containing complex GO:0032991 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified HIST1H3A in sEVs
1
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
2
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
3
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
5
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
8
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
9
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
10
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
21
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
30
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
31
Experiment ID 143
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
32
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
33
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for HIST1H3A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
2 CDCA2 157313
Proximity Label-MS Homo sapiens
3 ING4  
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
4 PPP1CB 5500
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
5 HDAC2 3066
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
6 UBE2A  
Affinity Capture-MS Homo sapiens
7 EIF3C 8663
Cross-Linking-MS (XL-MS) Homo sapiens
8 TOP2B 7155
Proximity Label-MS Homo sapiens
9 HNRNPK 3190
Cross-Linking-MS (XL-MS) Homo sapiens
10 WDR87  
Cross-Linking-MS (XL-MS) Homo sapiens
11 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
12 PPP1CC 5501
Cross-Linking-MS (XL-MS) Homo sapiens
13 BRD2  
Proximity Label-MS Homo sapiens
14 UBC 7316
Cross-Linking-MS (XL-MS) Homo sapiens
15 DNAH8 1769
Cross-Linking-MS (XL-MS) Homo sapiens
16 TAF1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Protein-peptide Homo sapiens
17 Ywhaz 22631
Reconstituted Complex Mus musculus
Affinity Capture-MS Mus musculus
18 PRKDC 5591
Co-localization Homo sapiens
19 PABPN1L  
Cross-Linking-MS (XL-MS) Homo sapiens
20 GPATCH4 54865
Proximity Label-MS Homo sapiens
21 HDAC3 8841
Reconstituted Complex Homo sapiens
22 LAMA2 3908
Cross-Linking-MS (XL-MS) Homo sapiens
23 GATAD2B 57459
Reconstituted Complex Homo sapiens
24 CHAF1A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 KIF23 9493
Proximity Label-MS Homo sapiens
26 UBE2K 3093
Affinity Capture-Western Homo sapiens
27 H2AFV 94239
Cross-Linking-MS (XL-MS) Homo sapiens
28 ATAD5  
Proximity Label-MS Homo sapiens
29 HELLS 3070
Proximity Label-MS Homo sapiens
30 MECP2 4204
Proximity Label-MS Homo sapiens
31 WDR5 11091
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
32 MTA2 9219
Affinity Capture-MS Homo sapiens
33 Hspa9 15526
Affinity Capture-MS Mus musculus
34 BRPF1  
Co-crystal Structure Homo sapiens
35 KIFC1 3833
Proximity Label-MS Homo sapiens
36 C11orf63  
Cross-Linking-MS (XL-MS) Homo sapiens
37 HIST1H2AG 8969
Cross-Linking-MS (XL-MS) Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 CARM1 10498
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
39 MYH9 4627
Cross-Linking-MS (XL-MS) Homo sapiens
40 TTN 7273
Cross-Linking-MS (XL-MS) Homo sapiens
41 CBX5 23468
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
42 SYNE1 23345
Cross-Linking-MS (XL-MS) Homo sapiens
43 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
Co-localization Homo sapiens
44 WHSC1L1  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
45 SUMO1 7341
Cross-Linking-MS (XL-MS) Homo sapiens
46 CAPN1 823
Cross-Linking-MS (XL-MS) Homo sapiens
47 AHCTF1 25909
Proximity Label-MS Homo sapiens
48 SRPK1 6732
Proximity Label-MS Homo sapiens
49 ATXN1 6310
Two-hybrid Homo sapiens
50 SMYD5 10322
Biochemical Activity Homo sapiens
51 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
52 HIST1H3F 8968
Affinity Capture-MS Homo sapiens
53 Hspa8 15481
Affinity Capture-MS Mus musculus
54 NASP 4678
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
55 TARBP1 6894
Cross-Linking-MS (XL-MS) Homo sapiens
56 LRRC59 55379
Cross-Linking-MS (XL-MS) Homo sapiens
57 TYMS 7298
Cross-Linking-MS (XL-MS) Homo sapiens
58 BKRF4  
Reconstituted Complex
59 SIRT7  
Reconstituted Complex Homo sapiens
60 BPTF 2186
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
61 EBNA1BP2 10969
Proximity Label-MS Homo sapiens
62 EPRS 2058
Cross-Linking-MS (XL-MS) Homo sapiens
63 RBBP4 5928
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 HIST1H2BO 8348
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
65 ZNF512  
Proximity Label-MS Homo sapiens
66 PRMT5 10419
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
67 HIST1H1B 3009
Cross-Linking-MS (XL-MS) Homo sapiens
Co-localization Homo sapiens
68 CTCFL  
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
69 SPEN 23013
Proximity Label-MS Homo sapiens
70 ESCO1  
Biochemical Activity Homo sapiens
71 WWC1  
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
72 KIAA1109 84162
Cross-Linking-MS (XL-MS) Homo sapiens
73 HIST1H1A 3024
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
74 PLCZ1  
Cross-Linking-MS (XL-MS) Homo sapiens
75 SGTA 6449
Cross-Linking-MS (XL-MS) Homo sapiens
76 HAT1 8520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
77 ASH1L 55870
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
78 PABPC3 5042
Cross-Linking-MS (XL-MS) Homo sapiens
79 IRF1  
Affinity Capture-Western Homo sapiens
80 GRIP1  
Biochemical Activity Homo sapiens
81 SUPT16H 11198
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
82 Ywhag 22628
Affinity Capture-MS Mus musculus
83 U2SURP 23350
Cross-Linking-MS (XL-MS) Homo sapiens
84 CDAN1 146059
Affinity Capture-MS Homo sapiens
85 HSPE1 3336
Cross-Linking-MS (XL-MS) Homo sapiens
86 RPS27A 6233
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
87 KAT8  
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
88 GRB2 2885
Affinity Capture-MS Homo sapiens
89 MTA1 9112
Proximity Label-MS Homo sapiens
90 HNRNPUL2 221092
Cross-Linking-MS (XL-MS) Homo sapiens
91 KMT2B  
Biochemical Activity Homo sapiens
92 PSMB7 5695
Cross-Linking-MS (XL-MS) Homo sapiens
93 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
94 BIN2 51411
Cross-Linking-MS (XL-MS) Homo sapiens
95 RUVBL2 10856
Cross-Linking-MS (XL-MS) Homo sapiens
96 SIRT1  
Biochemical Activity Homo sapiens
97 HDAC8 55869
Biochemical Activity Homo sapiens
98 PARP2  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 DYNC1H1 1778
Cross-Linking-MS (XL-MS) Homo sapiens
100 MED16 10025
Affinity Capture-MS Homo sapiens
101 ERCC6  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
102 GAPDH 2597
Cross-Linking-MS (XL-MS) Homo sapiens
103 Rbm25  
Affinity Capture-MS Mus musculus
104 ACO2 50
Affinity Capture-MS Homo sapiens
105 FOLH1B  
Proximity Label-MS Homo sapiens
106 EHMT1  
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Proximity Label-MS Homo sapiens
107 PRRC2C 23215
Cross-Linking-MS (XL-MS) Homo sapiens
108 HNF1B  
Reconstituted Complex Homo sapiens
109 Prpf40a  
Affinity Capture-MS Mus musculus
110 DNMT1 1786
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
111 PHF8  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
112 LUC7L 55692
Cross-Linking-MS (XL-MS) Homo sapiens
113 KNOP1 400506
Proximity Label-MS Homo sapiens
114 MORC2  
Affinity Capture-Western Homo sapiens
115 CDCA5  
Proximity Label-MS Homo sapiens
116 H2AFJ 55766
Cross-Linking-MS (XL-MS) Homo sapiens
117 SMC3 9126
Cross-Linking-MS (XL-MS) Homo sapiens
118 CAMSAP1 157922
Cross-Linking-MS (XL-MS) Homo sapiens
119 ANP32A 8125
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
120 KAT5  
Biochemical Activity Homo sapiens
121 BTF3 689
Affinity Capture-MS Homo sapiens
122 VPRBP 9730
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
123 NACA 4666
Cross-Linking-MS (XL-MS) Homo sapiens
124 THRAP3 9967
Cross-Linking-MS (XL-MS) Homo sapiens
125 PCDH11X  
Cross-Linking-MS (XL-MS) Homo sapiens
126 TRIM33 51592
Protein-peptide Homo sapiens
127 ATM 472
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
128 RBM34  
Proximity Label-MS Homo sapiens
129 SETDB1  
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
130 PSIP1 11168
Proximity Label-MS Homo sapiens
131 DAXX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 XRCC1 7515
Proximity Label-MS Homo sapiens
133 NR1H4  
Biochemical Activity Homo sapiens
134 NCOR1  
Reconstituted Complex Homo sapiens
135 KIF22  
Proximity Label-MS Homo sapiens
136 ZFHX3  
Cross-Linking-MS (XL-MS) Homo sapiens
137 MPHOSPH8 54737
Protein-peptide Homo sapiens
138 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
139 NPM1 4869
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
140 MDC1  
Proximity Label-MS Homo sapiens
141 MKI67  
Proximity Label-MS Homo sapiens
142 GRWD1 83743
Affinity Capture-Western Homo sapiens
143 DNAJC7 7266
Cross-Linking-MS (XL-MS) Homo sapiens
144 ZNF644  
Proximity Label-MS Homo sapiens
145 NSD1  
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
146 PHF1  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
147 SETD1A 9739
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
148 USP7 7874
Biochemical Activity Homo sapiens
149 DNAH2 146754
Cross-Linking-MS (XL-MS) Homo sapiens
150 MAD2L1 4085
Reconstituted Complex Homo sapiens
151 DLGAP5  
Cross-Linking-MS (XL-MS) Homo sapiens
152 GSK3B 2932
Affinity Capture-MS Homo sapiens
153 GAR1 54433
Cross-Linking-MS (XL-MS) Homo sapiens
154 YWHAB 7529
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
155 CCT2 10576
Cross-Linking-MS (XL-MS) Homo sapiens
156 MCM6 4175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 HIST2H3C 126961
Affinity Capture-MS Homo sapiens
158 UBN2  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
159 RLF 6018
Proximity Label-MS Homo sapiens
160 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
161 HNRNPA0 10949
Cross-Linking-MS (XL-MS) Homo sapiens
162 HIST1H4A 8359
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
163 TOP3B 8940
Affinity Capture-MS Homo sapiens
164 CABIN1  
Affinity Capture-MS Homo sapiens
165 WHSC1 7468
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
166 CCNB3  
Cross-Linking-MS (XL-MS) Homo sapiens
167 NBN 4683
Affinity Capture-Western Homo sapiens
168 TRIM24  
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
169 VRK1 7443
Proximity Label-MS Homo sapiens
170 BCAS3 54828
Reconstituted Complex Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
171 RPL35 11224
Cross-Linking-MS (XL-MS) Homo sapiens
172 RAG1  
Biochemical Activity Homo sapiens
173 HIST3H2BB 128312
Cross-Linking-MS (XL-MS) Homo sapiens
174 HMOX2 3163
Cross-Linking-MS (XL-MS) Homo sapiens
175 RAD18  
Affinity Capture-MS Homo sapiens
176 RLIM 51132
Affinity Capture-MS Homo sapiens
177 LUC7L2 51631
Cross-Linking-MS (XL-MS) Homo sapiens
178 HIST2H2AC 8338
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
179 MBD2 8932
Proximity Label-MS Homo sapiens
180 UBTF 7343
Proximity Label-MS Homo sapiens
181 GSG2  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
182 CTR9 9646
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
183 ACTR10 55860
Cross-Linking-MS (XL-MS) Homo sapiens
184 l(1)G0148  
Biochemical Activity Drosophila melanogaster
185 SETD7 80854
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
186 PMVK 10654
Cross-Linking-MS (XL-MS) Homo sapiens
187 TPX2  
Proximity Label-MS Homo sapiens
188 PHIP 55023
Proximity Label-MS Homo sapiens
189 SMCHD1 23347
Proximity Label-MS Homo sapiens
190 LEO1 123169
Affinity Capture-Western Homo sapiens
191 TP53BP1 7158
Co-crystal Structure Homo sapiens
192 ZBTB24  
Affinity Capture-Western Homo sapiens
193 TAF1B  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
194 CYLC2  
Cross-Linking-MS (XL-MS) Homo sapiens
195 SETD2  
Biochemical Activity Homo sapiens
Protein-peptide Homo sapiens
196 CSRP2BP  
Biochemical Activity Homo sapiens
197 EGFR 1956
Cross-Linking-MS (XL-MS) Homo sapiens
198 HNRNPA1L2 144983
Cross-Linking-MS (XL-MS) Homo sapiens
199 Ywhae 22627
Affinity Capture-MS Mus musculus
200 HIST3H3 8290
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
201 Kat2a  
Biochemical Activity Mus musculus
202 EFTUD2 9343
Cross-Linking-MS (XL-MS) Homo sapiens
203 SET 6418
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
204 EHMT2 10919
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
205 NIPBL 25836
Proximity Label-MS Homo sapiens
206 DDB1 1642
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
207 BMI1  
Affinity Capture-Western Homo sapiens
208 HIST1H1T 3010
Cross-Linking-MS (XL-MS) Homo sapiens
209 SIRT3  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
210 Wdr41  
Affinity Capture-MS Mus musculus
211 TAF4 6874
Cross-Linking-MS (XL-MS) Homo sapiens
212 PIN4 5303
Cross-Linking-MS (XL-MS) Homo sapiens
213 DSP 1832
Cross-Linking-MS (XL-MS) Homo sapiens
214 GATAD2A 54815
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
215 RPL13 6137
Cross-Linking-MS (XL-MS) Homo sapiens
216 HMGB4  
Cross-Linking-MS (XL-MS) Homo sapiens
217 CEP290  
Cross-Linking-MS (XL-MS) Homo sapiens
218 UBN1  
Affinity Capture-MS Homo sapiens
219 GPBP1  
Cross-Linking-MS (XL-MS) Homo sapiens
220 TAF1A  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
221 H3F3A 3020
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
222 NUCKS1 64710
Cross-Linking-MS (XL-MS) Homo sapiens
223 HDAC6 10013
Reconstituted Complex Homo sapiens
224 ADAMTS14  
Cross-Linking-MS (XL-MS) Homo sapiens
225 RIF1  
Proximity Label-MS Homo sapiens
226 FAM71E2  
Cross-Linking-MS (XL-MS) Homo sapiens
227 PRMT7  
Biochemical Activity Homo sapiens
228 KDM4C  
Biochemical Activity Homo sapiens
229 PRDM6 93166
Affinity Capture-Western Homo sapiens
230 PHF19  
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
231 DAW1  
Affinity Capture-MS Homo sapiens
232 SETD1B 23067
Biochemical Activity Homo sapiens
233 NAV3 89795
Cross-Linking-MS (XL-MS) Homo sapiens
234 ESR1  
Affinity Capture-MS Homo sapiens
235 Puf60 67959
Affinity Capture-MS Mus musculus
236 PRKCA 5578
Biochemical Activity Homo sapiens
237 DDX42 11325
Cross-Linking-MS (XL-MS) Homo sapiens
238 MTA3 57504
Proximity Label-MS Homo sapiens
239 KAT6A  
Biochemical Activity Homo sapiens
240 ANK3  
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
241 CKAP4 10970
Cross-Linking-MS (XL-MS) Homo sapiens
242 PSMD3 5709
Cross-Linking-MS (XL-MS) Homo sapiens
243 PRMT1 3276
Biochemical Activity Homo sapiens
244 Uhrf1  
Affinity Capture-Western Mus musculus
Biochemical Activity Mus musculus
Far Western Mus musculus
Protein-peptide Mus musculus
245 RCOR1  
Affinity Capture-Western Homo sapiens
246 CUL4A 8451
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
247 RALY 22913
Affinity Capture-MS Homo sapiens
248 XPC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 MCM7 4176
Affinity Capture-MS Homo sapiens
250 CBX1 10951
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
251 SNRPG 6637
Cross-Linking-MS (XL-MS) Homo sapiens
252 ANK2 287
Cross-Linking-MS (XL-MS) Homo sapiens
253 DNAJC8 22826
Cross-Linking-MS (XL-MS) Homo sapiens
254 YWHAE 7531
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
255 CENPC  
Proximity Label-MS Homo sapiens
256 HIST1H2BJ 8970
Cross-Linking-MS (XL-MS) Homo sapiens
257 EGLN1 54583
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
258 RET 5979
Affinity Capture-MS Homo sapiens
259 DNAH1 25981
Cross-Linking-MS (XL-MS) Homo sapiens
260 MYOD1  
Affinity Capture-Western Homo sapiens
261 ZMAT2  
Proximity Label-MS Homo sapiens
262 HIST2H2AA3 8337
Cross-Linking-MS (XL-MS) Homo sapiens
263 KAT7  
Biochemical Activity Homo sapiens
264 BAZ2A  
Proximity Label-MS Homo sapiens
265 TRIM28 10155
Co-localization Homo sapiens
266 HIST1H2BM 8342
Cross-Linking-MS (XL-MS) Homo sapiens
267 MCM2 4171
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
268 BAZ1A 11177
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
269 SMARCA1 6594
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
270 SPAG9 9043
Cross-Linking-MS (XL-MS) Homo sapiens
271 KDM2A  
Proximity Label-MS Homo sapiens
272 NFE2L2 4780
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
273 LASP1 3927
Affinity Capture-Western Homo sapiens
274 SUV39H1  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
275 KMT2D 8085
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
276 MBD1  
Affinity Capture-Western Homo sapiens
277 HIST2H3PS2 440686
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 PSMC2 5701
Cross-Linking-MS (XL-MS) Homo sapiens
279 SRP14 6727
Cross-Linking-MS (XL-MS) Homo sapiens
280 HMGA2 8091
Proximity Label-MS Homo sapiens
281 RCC1 1104
Reconstituted Complex Homo sapiens
282 ITGA4 3676
Affinity Capture-MS Homo sapiens
283 ATRX 546
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
284 RPL29 6159
Cross-Linking-MS (XL-MS) Homo sapiens
285 PALB2  
Affinity Capture-Western Homo sapiens
286 TMEM132D  
Two-hybrid Homo sapiens
287 SMARCA2 6595
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
288 GPRIN1 114787
Cross-Linking-MS (XL-MS) Homo sapiens
289 HIST2H4A 8370
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 MSL3  
Biochemical Activity Homo sapiens
291 HSPA8 3312
Reconstituted Complex Homo sapiens
292 MDH2 4191
Cross-Linking-MS (XL-MS) Homo sapiens
293 CHD1 1105
Co-crystal Structure Homo sapiens
Proximity Label-MS Homo sapiens
294 PPM1D  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
295 PTGES2 80142
Cross-Linking-MS (XL-MS) Homo sapiens
296 FAT4 79633
Cross-Linking-MS (XL-MS) Homo sapiens
297 MYO18A 399687
Cross-Linking-MS (XL-MS) Homo sapiens
298 LMNA 4000
Cross-Linking-MS (XL-MS) Homo sapiens
299 SHPRH  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
300 NEB 4703
Cross-Linking-MS (XL-MS) Homo sapiens
301 KAT6B  
Biochemical Activity Homo sapiens
302 BTF3L4 91408
Cross-Linking-MS (XL-MS) Homo sapiens
303 MYH15  
Cross-Linking-MS (XL-MS) Homo sapiens
304 BLM 641
Proximity Label-MS Homo sapiens
305 Ywhaq 22630
Affinity Capture-MS Mus musculus
306 DNMT3A 1788
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
307 CAST 831
Cross-Linking-MS (XL-MS) Homo sapiens
308 NOP2 4839
Cross-Linking-MS (XL-MS) Homo sapiens
309 CBX3 11335
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
310 WDR61 80349
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
311 HIST1H1D 3007
Cross-Linking-MS (XL-MS) Homo sapiens
312 MAPT  
Cross-Linking-MS (XL-MS) Homo sapiens
313 DEK 7913
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
314 RPA2 6118
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
315 BARD1 580
Affinity Capture-Western Homo sapiens
316 HIST1H1E 3008
Cross-Linking-MS (XL-MS) Homo sapiens
Co-localization Homo sapiens
317 CDH1 999
Proximity Label-MS Homo sapiens
318 RPL36 25873
Cross-Linking-MS (XL-MS) Homo sapiens
319 KIF11 3832
Affinity Capture-MS Homo sapiens
320 PARP10 84875
Biochemical Activity Homo sapiens
321 HMBS 3145
Cross-Linking-MS (XL-MS) Homo sapiens
322 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
323 L3MBTL2  
Protein-peptide Homo sapiens
324 PELP1 27043
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
325 CSTB 1476
Affinity Capture-Western Homo sapiens
326 HDAC5 10014
Reconstituted Complex Homo sapiens
327 DNTTIP2  
Proximity Label-MS Homo sapiens
328 KIF20B  
Proximity Label-MS Homo sapiens
329 KDM5A  
Biochemical Activity Homo sapiens
330 H3F3C 440093
Cross-Linking-MS (XL-MS) Homo sapiens
331 Hat1  
Affinity Capture-MS Mus musculus
Reconstituted Complex Mus musculus
332 RAN 5901
Cross-Linking-MS (XL-MS) Homo sapiens
333 HIST1H2AI 8329
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
334 WDR46  
Cross-Linking-MS (XL-MS) Homo sapiens
335 TONSL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
336 OLA1 29789
Cross-Linking-MS (XL-MS) Homo sapiens
337 KMT2A  
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Proximity Label-MS Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
338 CDC73  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
339 CHERP 10523
Cross-Linking-MS (XL-MS) Homo sapiens
340 BAZ1B 9031
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
341 SMARCA5 8467
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
342 MGA  
Proximity Label-MS Homo sapiens
343 RSF1  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
344 AHNAK 79026
Cross-Linking-MS (XL-MS) Homo sapiens
345 HIST2H4B 554313
Proximity Label-MS Homo sapiens
346 UHRF2  
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
347 Rbbp7 245688
Affinity Capture-MS Mus musculus
348 H1F0 3005
Proximity Label-MS Homo sapiens
349 POLR2A 5430
Cross-Linking-MS (XL-MS) Homo sapiens
350 RFC1 5981
Proximity Label-MS Homo sapiens
351 PDCD4 27250
Cross-Linking-MS (XL-MS) Homo sapiens
352 TOP1 7150
Proximity Label-MS Homo sapiens
353 SOX11  
Cross-Linking-MS (XL-MS) Homo sapiens
354 HP1BP3 50809
Proximity Label-MS Homo sapiens
355 DNAJC3 5611
Cross-Linking-MS (XL-MS) Homo sapiens
356 KDM8  
Biochemical Activity Homo sapiens
357 PARP1 142
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
358 PUS1 80324
Cross-Linking-MS (XL-MS) Homo sapiens
359 SFMBT1 51460
Affinity Capture-Western Homo sapiens
360 HDGF 3068
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
361 XRCC5 7520
Proximity Label-MS Homo sapiens
362 CHD7  
Proximity Label-MS Homo sapiens
363 CBX7  
Affinity Capture-Western Homo sapiens
364 PHB2 11331
Cross-Linking-MS (XL-MS) Homo sapiens
365 GIPC1 10755
Cross-Linking-MS (XL-MS) Homo sapiens
366 SLC25A6 293
Cross-Linking-MS (XL-MS) Homo sapiens
367 LIG3 3980
Proximity Label-MS Homo sapiens
368 MRPL11 65003
Cross-Linking-MS (XL-MS) Homo sapiens
369 ASF1B  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
370 MCM5 4174
Affinity Capture-MS Homo sapiens
371 KAT2B  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-localization Homo sapiens
372 Rbbp4 19646
Affinity Capture-MS Mus musculus
373 RPA1 6117
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
374 MEN1 4221
Biochemical Activity Homo sapiens
375 ZZEF1 23140
Cross-Linking-MS (XL-MS) Homo sapiens
376 PDHA1 5160
Affinity Capture-MS Homo sapiens
377 PBRM1 55193
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Proximity Label-MS Homo sapiens
378 CREBBP  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
379 FBXO44  
Affinity Capture-Western Homo sapiens
380 MORC3 23515
Proximity Label-MS Homo sapiens
381 KIFAP3 22920
Affinity Capture-Western Homo sapiens
382 KDM6B 23135
Biochemical Activity Homo sapiens
383 TOP2A 7153
Proximity Label-MS Homo sapiens
384 PCNA 5111
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
385 HDGFRP2 84717
Cross-Linking-MS (XL-MS) Homo sapiens
386 KDM1A 23028
Biochemical Activity Homo sapiens
Protein-peptide Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
387 CDK13 8621
Cross-Linking-MS (XL-MS) Homo sapiens
388 LRRK2 120892
Affinity Capture-MS Homo sapiens
389 SRCAP  
Proximity Label-MS Homo sapiens
390 SARNP 84324
Proximity Label-MS Homo sapiens
391 EID1  
Reconstituted Complex Homo sapiens
392 UHRF1 29128
Protein-peptide Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Protein-peptide Homo sapiens
Biochemical Activity Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Proximity Label-MS Homo sapiens
Protein-peptide Homo sapiens
393 KDM2B 84678
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
394 RAC1 5879
Affinity Capture-MS Homo sapiens
395 PRKCB 5579
Biochemical Activity Homo sapiens
396 SSRP1 6749
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
397 DYNC2H1 79659
Cross-Linking-MS (XL-MS) Homo sapiens
398 KIF4A 24137
Proximity Label-MS Homo sapiens
399 TIMM44 10469
Cross-Linking-MS (XL-MS) Homo sapiens
400 EP300 2033
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
401 HNRNPA2B1 3181
Cross-Linking-MS (XL-MS) Homo sapiens
402 SLFN11 91607
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
403 AP2B1 163
Proximity Label-MS Homo sapiens
404 ZNF280C  
Proximity Label-MS Homo sapiens
405 KMT2C 58508
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
406 PAXIP1  
Biochemical Activity Homo sapiens
407 TLK2  
Affinity Capture-MS Homo sapiens
408 RACGAP1 29127
Proximity Label-MS Homo sapiens
409 TSSK6 83983
Biochemical Activity Homo sapiens
410 TNRC18  
Cross-Linking-MS (XL-MS) Homo sapiens
411 PHLDA2 7262
Cross-Linking-MS (XL-MS) Homo sapiens
412 TAF3 83860
Cross-Linking-MS (XL-MS) Homo sapiens
413 HIST1H2BB 3018
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
414 KDM6A  
Biochemical Activity Homo sapiens
415 BASP1 10409
Cross-Linking-MS (XL-MS) Homo sapiens
416 INCENP 3619
Proximity Label-MS Homo sapiens
417 KDM4A  
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
418 NAV2  
Cross-Linking-MS (XL-MS) Homo sapiens
419 XIRP2  
Cross-Linking-MS (XL-MS) Homo sapiens
420 SNRPD2 6633
Cross-Linking-MS (XL-MS) Homo sapiens
421 ANKRD18B 441459
Cross-Linking-MS (XL-MS) Homo sapiens
422 USP36  
Affinity Capture-MS Homo sapiens
423 TRIM49  
Cross-Linking-MS (XL-MS) Homo sapiens
424 CHD4 1108
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-localization Homo sapiens
Protein-peptide Homo sapiens
425 Ywhab 54401
Affinity Capture-MS Mus musculus
426 ROCK2 9475
Cross-Linking-MS (XL-MS) Homo sapiens
427 DYRK1A 1859
Biochemical Activity Homo sapiens
428 ZNF280D  
Proximity Label-MS Homo sapiens
429 ANP32B 10541
Reconstituted Complex Homo sapiens
430 Hspa1b 15511
Affinity Capture-MS Mus musculus
431 CUX1 1523
Proximity Label-MS Homo sapiens
432 ZNF512B  
Proximity Label-MS Homo sapiens
433 C4orf27  
Reconstituted Complex Homo sapiens
434 YWHAG 7532
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
435 HMGA1 3159
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
436 CCDC6 8030
Cross-Linking-MS (XL-MS) Homo sapiens
437 LRRC4B  
Cross-Linking-MS (XL-MS) Homo sapiens
438 EED  
Far Western Homo sapiens
Proximity Label-MS Homo sapiens
439 NUSAP1 51203
Proximity Label-MS Homo sapiens
440 ASH2L 9070
Biochemical Activity Homo sapiens
441 SPHK2 56848
Affinity Capture-Western Homo sapiens
442 ARHGAP10 79658
Cross-Linking-MS (XL-MS) Homo sapiens
443 H2AFY2 55506
Cross-Linking-MS (XL-MS) Homo sapiens
Proximity Label-MS Homo sapiens
444 CHD3 1107
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
445 ADSS 159
Affinity Capture-MS Homo sapiens
446 ALG5 29880
Cross-Linking-MS (XL-MS) Homo sapiens
447 TRIP12 9320
Proximity Label-MS Homo sapiens
448 COBLL1 22837
Cross-Linking-MS (XL-MS) Homo sapiens
449 SETD8  
Affinity Capture-MS Homo sapiens
450 H2AFZ 3015
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
451 PPP1CA 5499
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
452 RBBP7 5931
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
453 BRIP1  
Affinity Capture-Western Homo sapiens
454 Rcc1  
Affinity Capture-MS Mus musculus
455 HMGN2 3151
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
456 REXO4  
Proximity Label-MS Homo sapiens
457 ATAD2 29028
Proximity Label-MS Homo sapiens
458 PRDM2  
Biochemical Activity Homo sapiens
459 GCC2 9648
Cross-Linking-MS (XL-MS) Homo sapiens
460 SMARCA4 6597
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
461 HMGN1  
Affinity Capture-MS Homo sapiens
462 SMC1A 8243
Cross-Linking-MS (XL-MS) Homo sapiens
463 MYH10 4628
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
464 BRD4 23476
FRET Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
465 Wdr5  
Affinity Capture-MS Mus musculus
466 H2AFY 9555
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
467 HIST1H2AB 8335
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
468 SMARCC2 6601
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
469 NUMA1 4926
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
470 Ywhah 22629
Affinity Capture-MS Mus musculus
471 COPS2 9318
Reconstituted Complex Homo sapiens
472 HIST1H3A 8350
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
473 RPL7A 6130
Cross-Linking-MS (XL-MS) Homo sapiens
474 YWHAZ 7534
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
475 CDCA8 55143
Proximity Label-MS Homo sapiens
476 PIEZO2  
Cross-Linking-MS (XL-MS) Homo sapiens
477 HIST2H2BF 440689
Proximity Label-MS Homo sapiens
478 PSMD8 5714
Cross-Linking-MS (XL-MS) Homo sapiens
479 CTNNB1 1499
Affinity Capture-MS Homo sapiens
480 GTF3C1  
Proximity Label-MS Homo sapiens
481 WIZ 58525
Proximity Label-MS Homo sapiens
482 UBR7  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
483 PALLD 23022
Cross-Linking-MS (XL-MS) Homo sapiens
484 PDIA3 2923
Cross-Linking-MS (XL-MS) Homo sapiens
485 ADNP 23394
Cross-Linking-MS (XL-MS) Homo sapiens
Proximity Label-MS Homo sapiens
486 RNF138  
Biochemical Activity Homo sapiens
487 Fhl3  
Affinity Capture-MS Mus musculus
488 MCM4 4173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
489 NAP1L1 4673
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
490 CTGLF11P  
Cross-Linking-MS (XL-MS) Homo sapiens
491 CBX2  
Proximity Label-MS Homo sapiens
492 SUZ12  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
493 PHF20  
Protein-peptide Homo sapiens
494 DNAH9  
Cross-Linking-MS (XL-MS) Homo sapiens
495 AURKB 9212
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
496 PAX5  
Affinity Capture-Western Homo sapiens
497 CDYL 9425
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
498 GLYR1 84656
Proximity Label-MS Homo sapiens
499 DKC1 1736
Cross-Linking-MS (XL-MS) Homo sapiens
500 MYO6 4646
Cross-Linking-MS (XL-MS) Homo sapiens
501 HIST1H2BA 255626
Cross-Linking-MS (XL-MS) Homo sapiens
502 AKAP5  
Affinity Capture-MS Homo sapiens
503 DNAJC9 23234
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
504 ASF1A 25842
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
505 AKT2 208
Biochemical Activity Homo sapiens
506 CDC45  
Affinity Capture-Western Homo sapiens
507 MMS22L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
508 SIRT2 22933
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
509 FBLIM1 54751
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
510 CHD8 57680
Proximity Label-MS Homo sapiens
511 SARS 6301
Cross-Linking-MS (XL-MS) Homo sapiens
512 Hspa4 15525
Affinity Capture-MS Mus musculus
513 BZW2 28969
Cross-Linking-MS (XL-MS) Homo sapiens
514 BRD3 8019
Cross-Linking-MS (XL-MS) Homo sapiens
Proximity Label-MS Homo sapiens
515 GNB2L1 10399
Affinity Capture-Western Homo sapiens
516 Pxn  
Affinity Capture-MS Mus musculus
517 H2AFX 3014
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-localization Homo sapiens
Co-localization Homo sapiens
518 PRR14L 253143
Cross-Linking-MS (XL-MS) Homo sapiens
519 LBR 3930
Reconstituted Complex Homo sapiens
520 SPTAN1 6709
Cross-Linking-MS (XL-MS) Homo sapiens
521 TAF15 8148
Reconstituted Complex Homo sapiens
522 PDZD2  
Cross-Linking-MS (XL-MS) Homo sapiens
523 KAT2A  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
524 SNAI1  
Affinity Capture-Western Homo sapiens
525 WBP11  
Cross-Linking-MS (XL-MS) Homo sapiens
526 UBA52 7311
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
527 HMGN5 79366
Cross-Linking-MS (XL-MS) Homo sapiens
528 SMNDC1  
Cross-Linking-MS (XL-MS) Homo sapiens
529 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
530 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
531 CREB1  
Affinity Capture-Western Homo sapiens
532 THAP7  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
533 E2F3  
Cross-Linking-MS (XL-MS) Homo sapiens
534 UBB 7314
Cross-Linking-MS (XL-MS) Homo sapiens
535 NUP50 10762
Cross-Linking-MS (XL-MS) Homo sapiens
536 EZH2  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Proximity Label-MS Homo sapiens
537 KIF18B 146909
Proximity Label-MS Homo sapiens
538 IPO4 79711
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
539 AIRE  
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
540 PXN 5829
Proximity Label-MS Homo sapiens
541 DNM3 26052
Cross-Linking-MS (XL-MS) Homo sapiens
542 XRCC6 2547
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
543 HIRA  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
544 HNRNPU 3192
Cross-Linking-MS (XL-MS) Homo sapiens
545 C9orf72  
Affinity Capture-MS Homo sapiens
546 USF1  
Cross-Linking-MS (XL-MS) Homo sapiens
547 PAF1 54623
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
548 CHAF1B  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
549 ESYT1 23344
Cross-Linking-MS (XL-MS) Homo sapiens
550 NEDD8 4738
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which HIST1H3A is involved
PathwayEvidenceSource
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 TAS Reactome
Activation of anterior HOX genes in hindbrain development during early embryogenesis IEA Reactome
Activation of HOX genes during differentiation IEA Reactome
Amyloid fiber formation TAS Reactome
Assembly of the ORC complex at the origin of replication TAS Reactome
Assembly of the pre-replicative complex TAS Reactome
B-WICH complex positively regulates rRNA expression TAS Reactome
Cell Cycle IEA Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cellular Senescence TAS Reactome
Chromatin modifications during the maternal to zygotic transition (MZT) IEA Reactome
Chromatin modifying enzymes TAS Reactome
Chromatin modifying enzymes IEA Reactome
Chromatin organization TAS Reactome
Chromatin organization IEA Reactome
Condensation of Prophase Chromosomes TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Cytokine Signaling in Immune system IEA Reactome
Defective pyroptosis TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Diseases of programmed cell death TAS Reactome
DNA methylation IEA Reactome
DNA Replication TAS Reactome
DNA Replication Pre-Initiation TAS Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes IEA Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes TAS Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes TAS Reactome
Epigenetic regulation of gene expression TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes TAS Reactome
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression IEA Reactome
ESR-mediated signaling TAS Reactome
Estrogen-dependent gene expression TAS Reactome
Factors involved in megakaryocyte development and platelet production TAS Reactome
Formation of the beta-catenin:TCF transactivating complex TAS Reactome
Gene expression (Transcription) TAS Reactome
Gene expression (Transcription) IEA Reactome
Gene Silencing by RNA TAS Reactome
Generic Transcription Pathway TAS Reactome
Generic Transcription Pathway IEA Reactome
HATs acetylate histones TAS Reactome
HATs acetylate histones IEA Reactome
HCMV Early Events TAS Reactome
HCMV Infection TAS Reactome
HCMV Late Events TAS Reactome
HDACs deacetylate histones TAS Reactome
HDMs demethylate histones TAS Reactome
Hemostasis TAS Reactome
Immune System TAS Reactome
Immune System IEA Reactome
Infectious disease TAS Reactome
Interleukin-7 signaling TAS Reactome
Interleukin-7 signaling IEA Reactome
M Phase TAS Reactome
Maternal to zygotic transition (MZT) IEA Reactome
Meiosis IEA Reactome
Meiotic recombination IEA Reactome
Metabolism of proteins TAS Reactome
Mitotic Prophase TAS Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis IEA Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis TAS Reactome
Negative epigenetic regulation of rRNA expression TAS Reactome
Negative epigenetic regulation of rRNA expression IEA Reactome
NoRC negatively regulates rRNA expression IEA Reactome
NoRC negatively regulates rRNA expression TAS Reactome
Oxidative Stress Induced Senescence TAS Reactome
PKMTs methylate histone lysines TAS Reactome
Positive epigenetic regulation of rRNA expression TAS Reactome
Positive epigenetic regulation of rRNA expression IEA Reactome
PRC2 methylates histones and DNA TAS Reactome
Pre-NOTCH Expression and Processing IEA Reactome
Pre-NOTCH Transcription and Translation IEA Reactome
Regulation of endogenous retroelements TAS Reactome
Regulation of endogenous retroelements IEA Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins TAS Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins IEA Reactome
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) IEA Reactome
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex TAS Reactome
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex IEA Reactome
Reproduction IEA Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases activate PKNs TAS Reactome
RMTs methylate histone arginines TAS Reactome
RNA Polymerase I Promoter Clearance TAS Reactome
RNA Polymerase I Promoter Escape TAS Reactome
RNA Polymerase I Promoter Opening TAS Reactome
RNA Polymerase I Transcription TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RNA Polymerase II Transcription IEA Reactome
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function TAS Reactome
RUNX1 regulates transcription of genes involved in differentiation of HSCs IEA Reactome
Senescence-Associated Secretory Phenotype (SASP) TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by Interleukins TAS Reactome
Signaling by Interleukins IEA Reactome
Signaling by NOTCH IEA Reactome
Signaling by Nuclear Receptors TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by WNT TAS Reactome
SIRT1 negatively regulates rRNA expression TAS Reactome
TCF dependent signaling in response to WNT TAS Reactome
Transcriptional regulation by RUNX1 TAS Reactome
Transcriptional regulation by RUNX1 IEA Reactome
Transcriptional regulation by small RNAs TAS Reactome
Transcriptional regulation of granulopoiesis IEA Reactome
Viral Infection Pathways TAS Reactome





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