Gene description for TUFM
Gene name Tu translation elongation factor, mitochondrial
Gene symbol TUFM
Other names/aliases COXPD4
EF-TuMT
EFTU
P43
Species Homo sapiens
 Database cross references - TUFM
ExoCarta ExoCarta_7284
Vesiclepedia VP_7284
Entrez Gene 7284
HGNC 12420
MIM 602389
UniProt P49411  
 TUFM identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 19415654    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for TUFM
Molecular Function
    RNA binding GO:0003723 HDA
    translation elongation factor activity GO:0003746 IBA
    translation elongation factor activity GO:0003746 IDA
    GTPase activity GO:0003924 IEA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
Biological Process
    translational elongation GO:0006414 IDA
    response to ethanol GO:0045471 IEA
    mitochondrial translational elongation GO:0070125 IBA
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial outer membrane GO:0005741 TAS
    membrane GO:0016020 HDA
    mitochondrial nucleoid GO:0042645 IDA
    synapse GO:0045202 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified TUFM in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 65
MISEV standards
✘ Biophysical techniques
✔
HSP60|HSP27|GAPDH|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19415654    
Organism Homo sapiens
Experiment description Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.
Authors "Staubach S, Razawi H, Hanisch FG."
Journal name PROTEOMICS
Publication year 2009
Sample Breast cancer cells
Sample name MCF-7
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
8
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
15
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
30
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
32
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
45
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for TUFM
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FDPS 2224
Co-fractionation Homo sapiens
2 UBL4A 8266
Affinity Capture-MS Homo sapiens
3 SKI 6497
Affinity Capture-MS Homo sapiens
4 NFATC1 4772
Affinity Capture-MS Homo sapiens
5 CAP1 10487
Co-fractionation Homo sapiens
6 MTG2  
Proximity Label-MS Homo sapiens
7 RBX1 9978
Co-fractionation Homo sapiens
8 C9orf78 51759
Affinity Capture-MS Homo sapiens
9 MRPL27 51264
Proximity Label-MS Homo sapiens
10 UBC 7316
Affinity Capture-MS Homo sapiens
11 GFM2 84340
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 MRPS18C  
Proximity Label-MS Homo sapiens
13 CUL7 9820
Affinity Capture-MS Homo sapiens
14 WDR76  
Affinity Capture-MS Homo sapiens
15 DTX3  
Affinity Capture-MS Homo sapiens
16 MRPL13  
Proximity Label-MS Homo sapiens
17 IARS2 55699
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
18 DEFA5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 HEXB 3074
Co-fractionation Homo sapiens
20 PPEF1  
Affinity Capture-MS Homo sapiens
21 HSP90B1 7184
Proximity Label-MS Homo sapiens
22 SLC30A9 10463
Proximity Label-MS Homo sapiens
23 MECP2 4204
Affinity Capture-MS Homo sapiens
24 NSFL1C 55968
Co-fractionation Homo sapiens
25 PREPL 9581
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 RPS11 6205
Co-fractionation Homo sapiens
27 MRPL47 57129
Proximity Label-MS Homo sapiens
28 RPL19 6143
Co-fractionation Homo sapiens
29 SLC25A3 5250
Co-fractionation Homo sapiens
30 KIF14 9928
Affinity Capture-MS Homo sapiens
31 RBMX 27316
Proximity Label-MS Homo sapiens
32 BAG5 9529
Affinity Capture-MS Homo sapiens
33 CLU 1191
Co-fractionation Homo sapiens
34 NLRX1 79671
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
35 TMEM25  
Affinity Capture-MS Homo sapiens
36 ESRRB  
Affinity Capture-MS Homo sapiens
37 PABPC1 26986
Co-fractionation Homo sapiens
38 YAP1 10413
Affinity Capture-MS Homo sapiens
39 TRIM21 6737
Affinity Capture-MS Homo sapiens
40 SLX4  
Affinity Capture-MS Homo sapiens
41 RPL31 6160
Co-fractionation Homo sapiens
42 MRPS6  
Proximity Label-MS Homo sapiens
43 VWA8 23078
Proximity Label-MS Homo sapiens
44 SYNCRIP 10492
Proximity Label-MS Homo sapiens
45 ECHS1 1892
Proximity Label-MS Homo sapiens
46 BANF1 8815
Affinity Capture-MS Homo sapiens
47 CYC1 1537
Co-fractionation Homo sapiens
48 DBT 1629
Proximity Label-MS Homo sapiens
49 CUL2 8453
Affinity Capture-MS Homo sapiens
50 CAPN1 823
Co-fractionation Homo sapiens
51 MRPL41 64975
Proximity Label-MS Homo sapiens
52 ANLN 54443
Affinity Capture-MS Homo sapiens
53 PNPLA8 50640
Proximity Label-MS Homo sapiens
54 MRPL14 64928
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
55 PLAA 9373
Co-fractionation Homo sapiens
56 RARS2  
Proximity Label-MS Homo sapiens
57 EARS2  
Proximity Label-MS Homo sapiens
58 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
59 HADHA 3030
Proximity Label-MS Homo sapiens
60 DAP3 7818
Proximity Label-MS Homo sapiens
61 MRPL24  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
62 NUBP2 10101
Co-fractionation Homo sapiens
63 YBX1 4904
Co-fractionation Homo sapiens
64 SIRT7  
Affinity Capture-MS Homo sapiens
65 PRKAR1A 5573
Co-fractionation Homo sapiens
66 MRPL16  
Proximity Label-MS Homo sapiens
67 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
68 DCPS 28960
Co-fractionation Homo sapiens
69 GADD45GIP1  
Proximity Label-MS Homo sapiens
70 HMBOX1  
Two-hybrid Homo sapiens
71 VARS2  
Proximity Label-MS Homo sapiens
72 GTF3C4 9329
Co-fractionation Homo sapiens
73 FN1 2335
Affinity Capture-MS Homo sapiens
74 HNRNPR 10236
Proximity Label-MS Homo sapiens
75 PCBP1 5093
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
76 RPA3 6119
Proximity Label-MS Homo sapiens
77 DLST 1743
Proximity Label-MS Homo sapiens
78 HSPA1A 3303
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
79 DLAT 1737
Proximity Label-MS Homo sapiens
80 NFATC2  
Affinity Capture-MS Homo sapiens
81 LYRM4 57128
Proximity Label-MS Homo sapiens
82 MRPL18 29074
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
83 RPS16 6217
Co-fractionation Homo sapiens
84 HSPE1 3336
Proximity Label-MS Homo sapiens
85 GRK5 2869
Affinity Capture-MS Homo sapiens
86 GLS 2744
Proximity Label-MS Homo sapiens
87 FBXL6  
Affinity Capture-MS Homo sapiens
88 CLPX 10845
Proximity Label-MS Homo sapiens
89 MACF1 23499
Co-fractionation Homo sapiens
90 ZEB1  
Affinity Capture-MS Homo sapiens
91 LARS2 23395
Proximity Label-MS Homo sapiens
92 COX5A 9377
Proximity Label-MS Homo sapiens
93 BMPR1A 657
Affinity Capture-MS Homo sapiens
94 HSP90AA1 3320
Co-fractionation Homo sapiens
95 ATAD3A 55210
Proximity Label-MS Homo sapiens
96 NIPSNAP1 8508
Proximity Label-MS Homo sapiens
97 NME4 4833
Proximity Label-MS Homo sapiens
98 RPS24 6229
Co-fractionation Homo sapiens
99 GAPDH 2597
Co-fractionation Homo sapiens
100 PPP1R2 5504
Co-fractionation Homo sapiens
101 HNRNPL 3191
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
102 ACOT1 641371
Proximity Label-MS Homo sapiens
103 FECH 2235
Proximity Label-MS Homo sapiens
104 THNSL1 79896
Proximity Label-MS Homo sapiens
105 MRPS16  
Proximity Label-MS Homo sapiens
106 AIMP1 9255
Co-fractionation Homo sapiens
107 RPL23A 6147
Co-fractionation Homo sapiens
108 EXOSC6 118460
Two-hybrid Homo sapiens
109 MRPL28 10573
Proximity Label-MS Homo sapiens
110 ABCB7 22
Proximity Label-MS Homo sapiens
111 NDUFS6  
Proximity Label-MS Homo sapiens
112 ASB14  
Affinity Capture-MS Homo sapiens
113 GTPBP3  
Proximity Label-MS Homo sapiens
114 PDHA1 5160
Proximity Label-MS Homo sapiens
115 AFG3L2 10939
Proximity Label-MS Homo sapiens
116 KIF23 9493
Affinity Capture-MS Homo sapiens
117 MRPL48  
Proximity Label-MS Homo sapiens
118 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 SARS2 54938
Co-fractionation Homo sapiens
120 ATP5J2-PTCD1  
Proximity Label-MS Homo sapiens
121 MRPS30 10884
Proximity Label-MS Homo sapiens
122 KLK5 25818
Affinity Capture-MS Homo sapiens
123 GTPBP10  
Proximity Label-MS Homo sapiens
124 BTF3 689
Affinity Capture-MS Homo sapiens
125 ADRB2  
Affinity Capture-MS Homo sapiens
126 UCHL1 7345
Affinity Capture-MS Homo sapiens
127 NOP56 10528
Affinity Capture-MS Homo sapiens
128 RPL14 9045
Co-fractionation Homo sapiens
129 NENF 29937
Co-fractionation Homo sapiens
130 MRPL49 740
Proximity Label-MS Homo sapiens
131 NDUFS2 4720
Proximity Label-MS Homo sapiens
132 RPS3 6188
Co-fractionation Homo sapiens
133 MUC20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 WTAP 9589
Affinity Capture-MS Homo sapiens
135 B3GNT2 10678
Affinity Capture-MS Homo sapiens
136 OGDH 4967
Proximity Label-MS Homo sapiens
137 HSPA2 3306
Co-fractionation Homo sapiens
138 NUDT19 390916
Proximity Label-MS Homo sapiens
139 SUPV3L1 6832
Proximity Label-MS Homo sapiens
140 HARS2 23438
Proximity Label-MS Homo sapiens
141 PRC1 9055
Affinity Capture-MS Homo sapiens
142 AP1G1 164
Co-fractionation Homo sapiens
143 NDUFA5 4698
Proximity Label-MS Homo sapiens
144 OBSL1 23363
Affinity Capture-MS Homo sapiens
145 DGAT2L6  
Two-hybrid Homo sapiens
146 RAB5B 5869
Co-fractionation Homo sapiens
147 LACTB 114294
Co-fractionation Homo sapiens
148 VCAM1 7412
Affinity Capture-MS Homo sapiens
149 DDX6 1656
Co-fractionation Homo sapiens
150 ETFA 2108
Proximity Label-MS Homo sapiens
151 MRPS7 51081
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
152 TACO1  
Proximity Label-MS Homo sapiens
153 FASTKD2  
Proximity Label-MS Homo sapiens
154 HK1 3098
Co-fractionation Homo sapiens
155 NACA2 342538
Co-fractionation Homo sapiens
156 QRSL1  
Proximity Label-MS Homo sapiens
157 LMAN1 3998
Co-fractionation Homo sapiens
158 GTF2I 2969
Co-fractionation Homo sapiens
159 NNT 23530
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
160 MRPS35 60488
Proximity Label-MS Homo sapiens
161 SEPHS1 22929
Co-fractionation Homo sapiens
162 CHMP7 91782
Co-fractionation Homo sapiens
163 PPP5C 5536
Co-fractionation Homo sapiens
164 ERO1L 30001
Co-fractionation Homo sapiens
165 MRPL45 84311
Proximity Label-MS Homo sapiens
166 NDUFA8 4702
Co-fractionation Homo sapiens
167 PPT2  
Co-fractionation Homo sapiens
168 ATPAF1  
Proximity Label-MS Homo sapiens
169 MRPL51 51258
Proximity Label-MS Homo sapiens
170 PDHX 8050
Proximity Label-MS Homo sapiens
171 PLK1 5347
Affinity Capture-MS Homo sapiens
172 POLDIP2 26073
Proximity Label-MS Homo sapiens
173 ASB10  
Affinity Capture-MS Homo sapiens
174 MRPL3  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
175 RNMTL1  
Proximity Label-MS Homo sapiens
176 AGPS 8540
Co-fractionation Homo sapiens
177 MRPL39 54148
Proximity Label-MS Homo sapiens
178 CYLD  
Affinity Capture-MS Homo sapiens
179 OGT 8473
Reconstituted Complex Homo sapiens
180 KDF1  
Affinity Capture-MS Homo sapiens
181 NDUFAF1  
Proximity Label-MS Homo sapiens
182 MRPL44  
Proximity Label-MS Homo sapiens
183 MRPL12 6182
Proximity Label-MS Homo sapiens
184 RPL32 6161
Co-fractionation Homo sapiens
185 IBA57  
Proximity Label-MS Homo sapiens
186 AIFM1 9131
Affinity Capture-MS Homo sapiens
187 CANX 821
Co-fractionation Homo sapiens
188 RPS2 6187
Co-fractionation Homo sapiens
189 XPO1 7514
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
190 MRPS11  
Proximity Label-MS Homo sapiens
191 MTIF3  
Two-hybrid Homo sapiens
192 CAMK1D 57118
Co-fractionation Homo sapiens
193 PPA1 5464
Co-fractionation Homo sapiens
194 MRPL9 65005
Proximity Label-MS Homo sapiens
195 ATP5F1 515
Proximity Label-MS Homo sapiens
196 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
197 HSD17B10 3028
Proximity Label-MS Homo sapiens
198 BCS1L 617
Proximity Label-MS Homo sapiens
199 FUS 2521
Affinity Capture-MS Homo sapiens
200 GAB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 SYP  
Two-hybrid Homo sapiens
202 CDK2 1017
Affinity Capture-MS Homo sapiens
203 BIRC6 57448
Affinity Capture-MS Homo sapiens
204 ZMYM6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 CNR2  
Affinity Capture-MS Homo sapiens
206 BAG1 573
Affinity Capture-MS Homo sapiens
207 IL12RB1  
Affinity Capture-MS Homo sapiens
208 CMTM5  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
209 ACAD9 28976
Proximity Label-MS Homo sapiens
210 RCN2 5955
Co-fractionation Homo sapiens
211 DDRGK1 65992
Affinity Capture-MS Homo sapiens
212 BMI1  
Affinity Capture-MS Homo sapiens
213 MRPS17 51373
Proximity Label-MS Homo sapiens
214 NDUFV2 4729
Proximity Label-MS Homo sapiens
215 BRD9 65980
Affinity Capture-MS Homo sapiens
216 ZDHHC15 158866
Two-hybrid Homo sapiens
217 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 EIF3H 8667
Affinity Capture-MS Homo sapiens
219 DSP 1832
Co-fractionation Homo sapiens
220 KRT18 3875
Co-fractionation Homo sapiens
221 CLPP 8192
Proximity Label-MS Homo sapiens
222 CS 1431
Proximity Label-MS Homo sapiens
223 C17orf80 55028
Proximity Label-MS Homo sapiens
224 SPOP  
Affinity Capture-MS Homo sapiens
225 SGK1  
Affinity Capture-MS Homo sapiens
226 ALDH4A1 8659
Proximity Label-MS Homo sapiens
227 POLG  
Proximity Label-MS Homo sapiens
228 PDPR 55066
Proximity Label-MS Homo sapiens
229 FOLR1 2348
Affinity Capture-MS Homo sapiens
230 ENG 2022
Co-fractionation Homo sapiens
231 ASB12  
Affinity Capture-MS Homo sapiens
232 PTBP1 5725
Co-fractionation Homo sapiens
233 PPP2R2C 5522
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
234 SCPEP1 59342
Co-fractionation Homo sapiens
235 PMPCA 23203
Proximity Label-MS Homo sapiens
236 RPS5 6193
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
237 RPS26 6231
Co-fractionation Homo sapiens
238 CHMP4C 92421
Affinity Capture-MS Homo sapiens
239 GFM1 85476
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
240 ARF1 375
Co-fractionation Homo sapiens
241 C1QBP 708
Affinity Capture-MS Homo sapiens
242 KRAS 3845
Negative Genetic Homo sapiens
243 ATOH1  
Affinity Capture-MS Homo sapiens
244 ASL 435
Co-fractionation Homo sapiens
245 PRMT1 3276
Affinity Capture-MS Homo sapiens
246 MRPS9 64965
Proximity Label-MS Homo sapiens
247 CHMP2A 27243
Co-fractionation Homo sapiens
248 MRPS27 23107
Proximity Label-MS Homo sapiens
249 SLIRP 81892
Proximity Label-MS Homo sapiens
250 RAB1A 5861
Co-fractionation Homo sapiens
251 NDUFS1 4719
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
252 MRPL30  
Proximity Label-MS Homo sapiens
253 MRPL17  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
254 ANGEL2 90806
Proximity Label-MS Homo sapiens
255 PDK3 5165
Proximity Label-MS Homo sapiens
256 FAM9B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
257 GATB  
Proximity Label-MS Homo sapiens
258 ARL6IP1 23204
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
259 RPS6KB2  
Affinity Capture-MS Homo sapiens
260 CARS2 79587
Proximity Label-MS Homo sapiens
261 LRPPRC 10128
Proximity Label-MS Homo sapiens
262 POR 5447
Co-fractionation Homo sapiens
263 HNRNPAB 3182
Proximity Label-MS Homo sapiens
264 RDX 5962
Co-fractionation Homo sapiens
265 NDUFS3 4722
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
266 CRYZ 1429
Proximity Label-MS Homo sapiens
267 PRKCDBP 112464
Co-fractionation Homo sapiens
268 MCM2 4171
Affinity Capture-MS Homo sapiens
269 SDHB 6390
Proximity Label-MS Homo sapiens
270 TIMMDC1  
Proximity Label-MS Homo sapiens
271 HINT2 84681
Proximity Label-MS Homo sapiens
272 BAGE2  
Affinity Capture-MS Homo sapiens
273 ST8SIA4 7903
Affinity Capture-MS Homo sapiens
274 NDUFV1 4723
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
275 ATG16L1 55054
Affinity Capture-MS Homo sapiens
276 NT5DC2 64943
Proximity Label-MS Homo sapiens
277 TFCP2 7024
Affinity Capture-MS Homo sapiens
278 MRPL4 51073
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
279 MTERF3  
Proximity Label-MS Homo sapiens
280 HSPA8 3312
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
281 MDH2 4191
Proximity Label-MS Homo sapiens
282 ALAS1  
Proximity Label-MS Homo sapiens
283 ATAD3B 83858
Proximity Label-MS Homo sapiens
284 MRPS25 64432
Proximity Label-MS Homo sapiens
285 MRPS33  
Proximity Label-MS Homo sapiens
286 P4HA1 5033
Co-fractionation Homo sapiens
287 THEM4  
Proximity Label-MS Homo sapiens
288 FASTKD5  
Proximity Label-MS Homo sapiens
289 RPL9 6133
Co-fractionation Homo sapiens
290 CUL4B 8450
Affinity Capture-MS Homo sapiens
291 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
292 COPE 11316
Affinity Capture-MS Homo sapiens
293 PAM16  
Proximity Label-MS Homo sapiens
294 CHMP4B 128866
Affinity Capture-MS Homo sapiens
295 RPA2 6118
Proximity Label-MS Homo sapiens
296 RAN 5901
Co-fractionation Homo sapiens
297 COPS5 10987
Affinity Capture-MS Homo sapiens
298 U2AF2 11338
Affinity Capture-MS Homo sapiens
299 C10orf2 56652
Proximity Label-MS Homo sapiens
300 PPA2 27068
Proximity Label-MS Homo sapiens
301 RPN1 6184
Co-fractionation Homo sapiens
302 NARS2  
Proximity Label-MS Homo sapiens
303 MRPL11 65003
Co-fractionation Homo sapiens
304 MRPL50 54534
Proximity Label-MS Homo sapiens
305 PSMD2 5708
Cross-Linking-MS (XL-MS) Homo sapiens
306 HDAC5 10014
Affinity Capture-MS Homo sapiens
307 ALDH2 217
Proximity Label-MS Homo sapiens
308 MRPL2 51069
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
309 IPO9 55705
Co-fractionation Homo sapiens
310 RPL11 6135
Co-fractionation Homo sapiens
311 HNRNPDL 9987
Proximity Label-MS Homo sapiens
312 APOE 348
Co-fractionation Homo sapiens
313 NTRK1 4914
Affinity Capture-MS Homo sapiens
314 ACAT1 38
Proximity Label-MS Homo sapiens
315 MRPL40 64976
Proximity Label-MS Homo sapiens
316 AK2 204
Co-fractionation Homo sapiens
317 METTL14  
Affinity Capture-MS Homo sapiens
318 POLR3A 11128
Co-fractionation Homo sapiens
319 TRMT10C 54931
Proximity Label-MS Homo sapiens
320 PNPT1 87178
Proximity Label-MS Homo sapiens
321 ECT2 1894
Affinity Capture-MS Homo sapiens
322 FAM60A  
Affinity Capture-MS Homo sapiens
323 MRPL37 51253
Proximity Label-MS Homo sapiens
324 EEF2 1938
Co-fractionation Homo sapiens
325 MRPS14  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
326 HSP90AB1 3326
Co-fractionation Homo sapiens
327 NR3C1 2908
Affinity Capture-MS Homo sapiens
328 ZC3H4 23211
Proximity Label-MS Homo sapiens
329 FBXO6 26270
Affinity Capture-MS Homo sapiens
330 DHX30 22907
Proximity Label-MS Homo sapiens
331 HNRNPUL1 11100
Proximity Label-MS Homo sapiens
332 CORO1C 23603
Co-fractionation Homo sapiens
333 MRPS28  
Proximity Label-MS Homo sapiens
334 GATC  
Proximity Label-MS Homo sapiens
335 MRPL19 9801
Proximity Label-MS Homo sapiens
336 RPS13 6207
Co-fractionation Homo sapiens
337 EMC2 9694
Co-fractionation Homo sapiens
338 HSDL2 84263
Proximity Label-MS Homo sapiens
339 RPL12 6136
Co-fractionation Homo sapiens
340 PPP6C 5537
Affinity Capture-MS Homo sapiens
341 MRPS36 92259
Proximity Label-MS Homo sapiens
342 RNF2  
Affinity Capture-MS Homo sapiens
343 HSPD1 3329
Co-fractionation Homo sapiens
344 MRPL38  
Proximity Label-MS Homo sapiens
345 PUS1 80324
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
346 METTL15  
Proximity Label-MS Homo sapiens
347 ILF3 3609
Co-fractionation Homo sapiens
348 PIGR 5284
Affinity Capture-MS Homo sapiens
349 PROSC 11212
Co-fractionation Homo sapiens
350 HIF1A 3091
Affinity Capture-MS Homo sapiens
351 TUBB2A 7280
Co-fractionation Homo sapiens
352 MTHFD2 10797
Proximity Label-MS Homo sapiens
353 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
354 PHB2 11331
Co-fractionation Homo sapiens
355 TSFM 10102
Proximity Label-MS Homo sapiens
356 ATP5J 522
Proximity Label-MS Homo sapiens
357 NDUFAF2  
Proximity Label-MS Homo sapiens
358 RPL6 6128
Co-fractionation Homo sapiens
359 UQCC1 55245
Proximity Label-MS Homo sapiens
360 GTPBP6  
Proximity Label-MS Homo sapiens
361 ICT1 3396
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
362 MRPL53  
Proximity Label-MS Homo sapiens
363 ALDH1B1 219
Co-fractionation Homo sapiens
364 TNFRSF10D 8793
Two-hybrid Homo sapiens
365 KIAA1429 25962
Affinity Capture-MS Homo sapiens
366 NDUFA12 55967
Proximity Label-MS Homo sapiens
367 GRPEL1 80273
Proximity Label-MS Homo sapiens
368 MRPS10 55173
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
369 TUBB6 84617
Co-fractionation Homo sapiens
370 UFL1 23376
Affinity Capture-MS Homo sapiens
371 GUF1  
Proximity Label-MS Homo sapiens
372 NDUFS8 4728
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
373 MRPS18B 28973
Proximity Label-MS Homo sapiens
374 NDUFA2 4695
Proximity Label-MS Homo sapiens
375 AARS2  
Proximity Label-MS Homo sapiens
376 TRMT5  
Proximity Label-MS Homo sapiens
377 MGME1  
Proximity Label-MS Homo sapiens
378 RPL8 6132
Co-fractionation Homo sapiens
379 METTL3  
Affinity Capture-MS Homo sapiens
380 MRPS22 56945
Proximity Label-MS Homo sapiens
381 FLAD1 80308
Proximity Label-MS Homo sapiens
382 BCKDHA 593
Co-fractionation Homo sapiens
383 TIMM44 10469
Proximity Label-MS Homo sapiens
384 EP300 2033
Affinity Capture-MS Homo sapiens
385 CAPN2 824
Co-fractionation Homo sapiens
386 UBE2H 7328
Affinity Capture-MS Homo sapiens
387 RIT1 6016
Negative Genetic Homo sapiens
388 C7orf55-LUC7L2  
Proximity Label-MS Homo sapiens
389 FMNL1 752
Affinity Capture-MS Homo sapiens
390 ATPIF1 93974
Proximity Label-MS Homo sapiens
391 SMURF1 57154
Affinity Capture-MS Homo sapiens
392 DPCD  
Proximity Label-MS Homo sapiens
393 USP5 8078
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
394 RPL37A 6168
Co-fractionation Homo sapiens
395 RPL15 6138
Co-fractionation Homo sapiens
396 MRPL10 124995
Proximity Label-MS Homo sapiens
397 ETFB 2109
Proximity Label-MS Homo sapiens
398 MCCC1 56922
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
399 MRPL52  
Proximity Label-MS Homo sapiens
400 PDHB 5162
Proximity Label-MS Homo sapiens
401 APP 351
Co-fractionation Homo sapiens
402 GSK3A 2931
Affinity Capture-MS Homo sapiens
403 HADH 3033
Proximity Label-MS Homo sapiens
404 ASB17  
Affinity Capture-MS Homo sapiens
405 KIF20A 10112
Affinity Capture-MS Homo sapiens
406 RPS20 6224
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
407 ATP5D 513
Proximity Label-MS Homo sapiens
408 MRPL20 55052
Proximity Label-MS Homo sapiens
409 PRDX3 10935
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
410 PC 5091
Co-fractionation Homo sapiens
411 TGFB1 7040
Affinity Capture-MS Homo sapiens
412 NDUFA7 4701
Proximity Label-MS Homo sapiens
413 SHMT2 6472
Proximity Label-MS Homo sapiens
414 MRPL23 6150
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
415 MRPS23 51649
Proximity Label-MS Homo sapiens
416 MRPS5 64969
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
417 FBXW7  
Affinity Capture-MS Homo sapiens
418 MRPS24 64951
Proximity Label-MS Homo sapiens
419 COA3 28958
Affinity Capture-Western Homo sapiens
420 WDR12 55759
Co-fractionation Homo sapiens
421 DDOST 1650
Co-fractionation Homo sapiens
422 MRPS26 64949
Proximity Label-MS Homo sapiens
423 ATP5O 539
Proximity Label-MS Homo sapiens
424 TSSK1B  
Affinity Capture-MS Homo sapiens
425 POLRMT 5442
Proximity Label-MS Homo sapiens
426 ATP5H 10476
Proximity Label-MS Homo sapiens
427 MYCN  
Affinity Capture-MS Homo sapiens
428 NDUFA6  
Proximity Label-MS Homo sapiens
429 MTIF2 4528
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
430 STOML2 30968
Proximity Label-MS Homo sapiens
431 GARS 2617
Proximity Label-MS Homo sapiens
432 LRRC59 55379
Co-fractionation Homo sapiens
433 TRMT61B  
Proximity Label-MS Homo sapiens
434 NDUFS4 4724
Proximity Label-MS Homo sapiens
435 MRPS34 65993
Proximity Label-MS Homo sapiens
436 ERBB3 2065
Affinity Capture-MS Homo sapiens
437 SFXN3 81855
Co-fractionation Homo sapiens
438 ACOT2 10965
Proximity Label-MS Homo sapiens
439 FUNDC1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
440 PTCD3 55037
Proximity Label-MS Homo sapiens
441 MMAB 326625
Proximity Label-MS Homo sapiens
442 VCP 7415
Co-fractionation Homo sapiens
443 TARS2 80222
Proximity Label-MS Homo sapiens
444 CRY2  
Affinity Capture-MS Homo sapiens
445 ERAL1  
Proximity Label-MS Homo sapiens
446 MRPL22  
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
447 RPS15A 6210
Co-fractionation Homo sapiens
448 NDUFAF3 25915
Proximity Label-MS Homo sapiens
449 ATP5B 506
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
450 COX4I1 1327
Proximity Label-MS Homo sapiens
451 MAT2A 4144
Co-fractionation Homo sapiens
452 PPIF 10105
Proximity Label-MS Homo sapiens
453 PDE12 201626
Proximity Label-MS Homo sapiens
454 SLC25A24 29957
Co-fractionation Homo sapiens
455 MRPL21 219927
Proximity Label-MS Homo sapiens
456 NDUFV3 4731
Proximity Label-MS Homo sapiens
457 FANCD2  
Affinity Capture-MS Homo sapiens
458 TRIM31  
Affinity Capture-MS Homo sapiens
459 NDUFB10 4716
Co-fractionation Homo sapiens
460 AMBRA1  
Affinity Capture-MS Homo sapiens
461 NDUFA9 4704
Proximity Label-MS Homo sapiens
462 LETM1 3954
Proximity Label-MS Homo sapiens
463 UQCRC2 7385
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
464 HMOX2 3163
Co-fractionation Homo sapiens
465 RLIM 51132
Affinity Capture-MS Homo sapiens
466 HCFC1 3054
Co-fractionation Homo sapiens
467 NFS1 9054
Proximity Label-MS Homo sapiens
468 RPS6 6194
Co-fractionation Homo sapiens
469 RPL3 6122
Co-fractionation Homo sapiens
470 ELAC2 60528
Proximity Label-MS Homo sapiens
471 PYCR2 29920
Proximity Label-MS Homo sapiens
472 RPL7 6129
Co-fractionation Homo sapiens
473 HIP1R 9026
Co-fractionation Homo sapiens
474 SUZ12  
Affinity Capture-MS Homo sapiens
475 MRPL15 29088
Proximity Label-MS Homo sapiens
476 AURKB 9212
Affinity Capture-MS Homo sapiens
477 ECI2 10455
Proximity Label-MS Homo sapiens
478 MRPL1  
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
479 AGO4  
Affinity Capture-MS Homo sapiens
480 MYO6 4646
Co-fractionation Homo sapiens
481 ASPH 444
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
482 SIRT2 22933
Affinity Capture-MS Homo sapiens
483 PLS3 5358
Co-fractionation Homo sapiens
484 CLTC 1213
Co-fractionation Homo sapiens
485 MRPL46  
Proximity Label-MS Homo sapiens
486 UBXN1 51035
Co-fractionation Homo sapiens
487 CCDC8  
Affinity Capture-MS Homo sapiens
488 RAB33A 9363
Affinity Capture-MS Homo sapiens
489 AK4 205
Proximity Label-MS Homo sapiens
490 DHX15 1665
Co-fractionation Homo sapiens
491 MRPL42  
Proximity Label-MS Homo sapiens
492 GLUD1 2746
Proximity Label-MS Homo sapiens
493 MRPS2 51116
Proximity Label-MS Homo sapiens
494 PDIA4 9601
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
495 PAFAH1B2 5049
Co-fractionation Homo sapiens
496 ZNF746  
Affinity Capture-MS Homo sapiens
497 MRPS31  
Proximity Label-MS Homo sapiens
498 SNCG 6623
Co-fractionation Homo sapiens
499 MRPL43 84545
Proximity Label-MS Homo sapiens
500 CUL5 8065
Affinity Capture-MS Homo sapiens
501 Ckap5 75786
Affinity Capture-MS Mus musculus
502 NDUFS7 374291
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
503 HIST1H1E 3008
Co-fractionation Homo sapiens
504 SUCLA2 8803
Proximity Label-MS Homo sapiens
505 NUP35 129401
Proximity Label-MS Homo sapiens
506 GSTM3 2947
Co-fractionation Homo sapiens
507 BECN1 8678
Affinity Capture-Western Homo sapiens
508 RPS23 6228
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
509 RPL23 9349
Co-fractionation Homo sapiens
510 PINK1  
Affinity Capture-MS Homo sapiens
511 RPS8 6202
Co-fractionation Homo sapiens
512 GRSF1 2926
Proximity Label-MS Homo sapiens
513 PTPRK 5796
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
514 NDUFAF4 29078
Proximity Label-MS Homo sapiens
515 C9orf72  
Affinity Capture-MS Homo sapiens
516 WARS 7453
Co-fractionation Homo sapiens
517 MRPS18A  
Proximity Label-MS Homo sapiens
518 RPL17 6139
Co-fractionation Homo sapiens
519 ECSIT 51295
Proximity Label-MS Homo sapiens
520 NAE1 8883
Co-fractionation Homo sapiens
521 DKKL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here