Gene description for RPL27A
Gene name ribosomal protein L27a
Gene symbol RPL27A
Other names/aliases L27A
Species Homo sapiens
 Database cross references - RPL27A
ExoCarta ExoCarta_6157
Vesiclepedia VP_6157
Entrez Gene 6157
HGNC 10329
MIM 603637
UniProt P46776  
 RPL27A identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPL27A
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 NAS
    protein binding GO:0005515 IPI
Biological Process
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    translation GO:0006412 NAS
Subcellular Localization
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 NAS
    endoplasmic reticulum GO:0005783 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    cytosolic large ribosomal subunit GO:0022625 HDA
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic ribosome GO:0022626 IDA
    synapse GO:0045202 IEA
 Experiment description of studies that identified RPL27A in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 494
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 496
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
14
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 274
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
38
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL27A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SIAH1  
Two-hybrid Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 SRP19 6728
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 LUZP4  
Affinity Capture-MS Homo sapiens
7 ISG15 9636
Affinity Capture-MS Homo sapiens
8 RPL26L1 51121
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
9 MRPL24  
Affinity Capture-MS Homo sapiens
10 TRMT1L 81627
Affinity Capture-MS Homo sapiens
11 SPRTN  
Affinity Capture-MS Homo sapiens
12 UBL4A 8266
Affinity Capture-MS Homo sapiens
13 QARS 5859
Co-fractionation Homo sapiens
14 WDR3  
Affinity Capture-MS Homo sapiens
15 RPS3A 6189
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
16 ZNF320  
Affinity Capture-MS Homo sapiens
17 EIF2S3 1968
Affinity Capture-MS Homo sapiens
18 MRPL30  
Affinity Capture-MS Homo sapiens
19 RPL30 6156
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
20 PPIE 10450
Affinity Capture-MS Homo sapiens
21 SSB 6741
Affinity Capture-MS Homo sapiens
22 ZNF431  
Affinity Capture-MS Homo sapiens
23 BTF3 689
Affinity Capture-MS Homo sapiens
24 VPRBP 9730
Affinity Capture-MS Homo sapiens
25 RPL13A 23521
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
26 RPL37A 6168
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
27 ABCF1 23
Co-fractionation Homo sapiens
28 EBNA-LP  
Affinity Capture-MS
29 RBAK  
Affinity Capture-MS Homo sapiens
30 NOP56 10528
Affinity Capture-MS Homo sapiens
31 EME1  
Affinity Capture-MS Homo sapiens
32 RPS19 6223
Co-fractionation Homo sapiens
33 RPL10 6134
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
34 RPL15 6138
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
35 MRPL1  
Affinity Capture-MS Homo sapiens
36 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
37 RPL14 9045
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
38 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
39 MRPL50 54534
Affinity Capture-MS Homo sapiens
40 RANBP3 8498
Co-fractionation Homo sapiens
41 CAND1 55832
Affinity Capture-MS Homo sapiens
42 MRPL38  
Affinity Capture-MS Homo sapiens
43 ZNF92  
Affinity Capture-MS Homo sapiens
44 PDZD8 118987
Affinity Capture-MS Homo sapiens
45 ZBTB1  
Affinity Capture-MS Homo sapiens
46 SOX2  
Affinity Capture-MS Homo sapiens
47 MRPL22  
Affinity Capture-MS Homo sapiens
48 FAU 2197
Co-fractionation Homo sapiens
49 RPS3 6188
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
50 RB1CC1 9821
Affinity Capture-MS Homo sapiens
51 ATG13 9776
Affinity Capture-MS Homo sapiens
52 RPS18 6222
Co-fractionation Homo sapiens
53 MRPS35 60488
Affinity Capture-MS Homo sapiens
54 CAPZB 832
Affinity Capture-MS Homo sapiens
55 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 RPS20 6224
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
57 METAP2 10988
Affinity Capture-MS Homo sapiens
58 MRPL20 55052
Affinity Capture-MS Homo sapiens
59 B3GNT2 10678
Affinity Capture-MS Homo sapiens
60 MRPL40 64976
Affinity Capture-MS Homo sapiens
61 PRC1 9055
Affinity Capture-MS Homo sapiens
62 GTF2F2 2963
Reconstituted Complex Homo sapiens
63 TGFB1 7040
Affinity Capture-MS Homo sapiens
64 KIF23 9493
Affinity Capture-MS Homo sapiens
65 MCM2 4171
Affinity Capture-MS Homo sapiens
66 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
67 FNTB 2342
Affinity Capture-MS Homo sapiens
68 EIF3B 8662
Affinity Capture-MS Homo sapiens
69 COPS5 10987
Affinity Capture-MS Homo sapiens
70 FBXW7  
Affinity Capture-MS Homo sapiens
71 RPL24 6152
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
72 MRPL45 84311
Affinity Capture-MS Homo sapiens
73 NPM1 4869
Affinity Capture-MS Homo sapiens
74 DDX24 57062
Affinity Capture-MS Homo sapiens
75 ZNF100  
Affinity Capture-MS Homo sapiens
76 HIST1H2AB 8335
Cross-Linking-MS (XL-MS) Homo sapiens
77 RPS9 6203
Co-fractionation Homo sapiens
78 GADD45GIP1  
Affinity Capture-MS Homo sapiens
79 GSPT1 2935
Affinity Capture-MS Homo sapiens
80 MALSU1  
Affinity Capture-MS Homo sapiens
81 ADARB1 104
Affinity Capture-MS Homo sapiens
82 DICER1  
Affinity Capture-MS Homo sapiens
83 PRKRA 8575
Affinity Capture-MS Homo sapiens
84 MRS2  
Affinity Capture-MS Homo sapiens
85 ITGA4 3676
Affinity Capture-MS Homo sapiens
86 EED  
Affinity Capture-MS Homo sapiens
87 SRP68 6730
Affinity Capture-MS Homo sapiens
88 KLF4  
Affinity Capture-MS Homo sapiens
89 VCAM1 7412
Affinity Capture-MS Homo sapiens
90 DDX6 1656
Affinity Capture-MS Homo sapiens
91 SFN 2810
Affinity Capture-MS Homo sapiens
92 ZNF346  
Affinity Capture-MS Homo sapiens
93 MECP2 4204
Affinity Capture-MS Homo sapiens
94 Eif3a 13669
Affinity Capture-MS Mus musculus
95 CUL1 8454
Affinity Capture-MS Homo sapiens
96 TFCP2 7024
Affinity Capture-MS Homo sapiens
97 ARIH2 10425
Affinity Capture-MS Homo sapiens
98 RBM42  
Affinity Capture-MS Homo sapiens
99 RNF220  
Affinity Capture-MS Homo sapiens
100 RPS11 6205
Co-fractionation Homo sapiens
101 MRPL47 57129
Affinity Capture-MS Homo sapiens
102 RPL19 6143
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
103 DVL2 1856
Affinity Capture-MS Homo sapiens
104 CTCF  
Affinity Capture-MS Homo sapiens
105 KIF14 9928
Affinity Capture-MS Homo sapiens
106 RPL10L 140801
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
107 PES1 23481
Co-fractionation Homo sapiens
108 MRPL39 54148
Affinity Capture-MS Homo sapiens
109 TPT1 7178
Affinity Capture-MS Homo sapiens
110 EMC9  
Affinity Capture-MS Homo sapiens
111 TRIM31  
Affinity Capture-MS Homo sapiens
112 AGO2 27161
Affinity Capture-RNA Homo sapiens
113 MRPS30 10884
Affinity Capture-MS Homo sapiens
114 CHMP4C 92421
Affinity Capture-MS Homo sapiens
115 RPS23 6228
Co-fractionation Homo sapiens
116 RPL27 6155
Co-fractionation Homo sapiens
117 SRP9 6726
Affinity Capture-MS Homo sapiens
118 RPS26 6231
Co-fractionation Homo sapiens
119 MRPL11 65003
Affinity Capture-MS Homo sapiens
120 MUS81  
Affinity Capture-MS Homo sapiens
121 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
122 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 RPL9 6133
Co-fractionation Homo sapiens
124 PRKCI 5584
Affinity Capture-MS Homo sapiens
125 CUL4B 8450
Affinity Capture-MS Homo sapiens
126 RPL4 6124
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
127 ZNF430  
Affinity Capture-MS Homo sapiens
128 CCAR2 57805
Co-fractionation Homo sapiens
129 RPS10 6204
Co-fractionation Homo sapiens
130 MARS 4141
Co-fractionation Homo sapiens
131 BLM 641
Affinity Capture-MS Homo sapiens
132 ZNF724P  
Affinity Capture-MS Homo sapiens
133 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
134 ZNF253  
Affinity Capture-MS Homo sapiens
135 VRK1 7443
Affinity Capture-MS Homo sapiens
136 RPL5 6125
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
137 RPL18A 6142
Co-fractionation Homo sapiens
138 TOP3B 8940
Affinity Capture-MS Homo sapiens
139 PABPC1 26986
Co-fractionation Homo sapiens
140 EEF1E1 9521
Co-fractionation Homo sapiens
141 CHMP4B 128866
Affinity Capture-MS Homo sapiens
142 HIST3H2BB 128312
Cross-Linking-MS (XL-MS) Homo sapiens
143 YAP1 10413
Affinity Capture-MS Homo sapiens
144 SRBD1  
Affinity Capture-MS Homo sapiens
145 VCP 7415
Affinity Capture-MS Homo sapiens
146 TRIM21 6737
Affinity Capture-MS Homo sapiens
147 MRPL51 51258
Affinity Capture-MS Homo sapiens
148 RPL31 6160
Co-fractionation Homo sapiens
149 RPS7 6201
Co-fractionation Homo sapiens
150 DTX2 113878
Proximity Label-MS Homo sapiens
151 TPM3 7170
Cross-Linking-MS (XL-MS) Homo sapiens
152 Srp72  
Affinity Capture-MS Mus musculus
153 RPL36 25873
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
154 RPA4  
Proximity Label-MS Homo sapiens
155 RPLP1 6176
Co-fractionation Homo sapiens
156 NOA1  
Affinity Capture-MS Homo sapiens
157 DHX9 1660
Co-fractionation Homo sapiens
158 HECTD1 25831
Affinity Capture-MS Homo sapiens
159 RIN3  
Affinity Capture-MS Homo sapiens
160 MAGOH 4116
Affinity Capture-MS Homo sapiens
161 RPLP0 6175
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
162 C3orf17  
Affinity Capture-MS Homo sapiens
163 MAGEB2 4113
Affinity Capture-MS Homo sapiens
164 CDK9 1025
Affinity Capture-MS Homo sapiens
165 RANBP6 26953
Affinity Capture-MS Homo sapiens
166 RPS15A 6210
Co-fractionation Homo sapiens
167 Ksr1  
Affinity Capture-MS Mus musculus
168 PRKACB 5567
Two-hybrid Homo sapiens
169 CYLD  
Affinity Capture-MS Homo sapiens
170 HNF1B  
Affinity Capture-MS Homo sapiens
171 LOC101929876 101929876
Co-fractionation Homo sapiens
172 MRPL2 51069
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 HMGB2 3148
Affinity Capture-MS Homo sapiens
174 RPL11 6135
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 PEX6  
Two-hybrid Homo sapiens
176 DUSP22  
Proximity Label-MS Homo sapiens
177 ZNF526  
Affinity Capture-MS Homo sapiens
178 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
179 MRPL44  
Affinity Capture-MS Homo sapiens
180 RPL32 6161
Co-fractionation Homo sapiens
181 RBM39 9584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 IPO5 3843
Affinity Capture-MS Homo sapiens
183 MRPL49 740
Affinity Capture-MS Homo sapiens
184 RPLP2 6181
Co-fractionation Homo sapiens
185 RPL23 9349
Co-fractionation Homo sapiens
186 RPS2 6187
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
187 KIF20A 10112
Affinity Capture-MS Homo sapiens
188 PANX1 24145
Proximity Label-MS Homo sapiens
189 RC3H2  
Affinity Capture-MS Homo sapiens
190 ZNF770 54989
Affinity Capture-MS Homo sapiens
191 DNAJC2 27000
Affinity Capture-MS Homo sapiens
192 DHX36 170506
Affinity Capture-MS Homo sapiens
193 RPL35 11224
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
194 TSPYL2  
Affinity Capture-MS Homo sapiens
195 RLIM 51132
Affinity Capture-MS Homo sapiens
196 GTF3C1  
Affinity Capture-MS Homo sapiens
197 MRPL9 65005
Affinity Capture-MS Homo sapiens
198 MRPL16  
Affinity Capture-MS Homo sapiens
199 CUL3 8452
Affinity Capture-MS Homo sapiens
200 RPS8 6202
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
201 RPL21 6144
Co-fractionation Homo sapiens
202 RPL3 6122
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
203 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 GTF3C2  
Affinity Capture-MS Homo sapiens
205 THOC5 8563
Affinity Capture-MS Homo sapiens
206 KIF2A 3796
Affinity Capture-MS Homo sapiens
207 FAM90A1  
Affinity Capture-MS Homo sapiens
208 NAP1L1 4673
Affinity Capture-MS Homo sapiens
209 BBX 56987
Affinity Capture-MS Homo sapiens
210 MYC  
Affinity Capture-MS Homo sapiens
211 RPL7 6129
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
212 FN1 2335
Affinity Capture-MS Homo sapiens
213 DHX57 90957
Affinity Capture-MS Homo sapiens
214 AURKB 9212
Affinity Capture-MS Homo sapiens
215 RPS27 6232
Co-fractionation Homo sapiens
216 CDK2 1017
Affinity Capture-MS Homo sapiens
217 AGO4  
Affinity Capture-MS Homo sapiens
218 NCAPH 23397
Affinity Capture-MS Homo sapiens
219 RPS27L 51065
Co-fractionation Homo sapiens
220 PCBP1 5093
Affinity Capture-MS Homo sapiens
221 MRPL4 51073
Affinity Capture-MS Homo sapiens
222 HNRNPA1 3178
Co-fractionation Homo sapiens
223 PSPC1 55269
Affinity Capture-MS Homo sapiens
224 RPA3 6119
Proximity Label-MS Homo sapiens
225 RPS13 6207
Co-fractionation Homo sapiens
226 INO80B 83444
Affinity Capture-MS Homo sapiens
227 EGFR 1956
Negative Genetic Homo sapiens
228 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
229 RPS14 6208
Co-fractionation Homo sapiens
230 RPL35A 6165
Co-fractionation Homo sapiens
231 RPL12 6136
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
232 GZF1  
Affinity Capture-MS Homo sapiens
233 RPL22 6146
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
234 MYCN  
Affinity Capture-MS Homo sapiens
235 Ktn1  
Affinity Capture-MS Mus musculus
236 PPP6C 5537
Affinity Capture-MS Homo sapiens
237 RPL23A 6147
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
238 RPL18 6141
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
239 DDRGK1 65992
Affinity Capture-MS Homo sapiens
240 RNF2  
Affinity Capture-MS Homo sapiens
241 NBPF1  
Affinity Capture-MS Homo sapiens
242 G3BP1 10146
Affinity Capture-MS Homo sapiens
243 Rpl35 66489
Affinity Capture-MS Mus musculus
244 FSCN1 6624
Affinity Capture-MS Homo sapiens
245 Eif3e 16341
Affinity Capture-MS Mus musculus
246 ZNF708  
Affinity Capture-MS Homo sapiens
247 BMP4 652
Affinity Capture-MS Homo sapiens
248 FTSJ3 117246
Affinity Capture-MS Homo sapiens
249 C9orf72  
Affinity Capture-MS Homo sapiens
250 UBA52 7311
Co-fractionation Homo sapiens
251 HUWE1 10075
Affinity Capture-MS Homo sapiens
252 ZNF493  
Affinity Capture-MS Homo sapiens
253 RPS16 6217
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
254 AIMP1 9255
Co-fractionation Homo sapiens
255 RPL13 6137
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
256 EIF2S1 1965
Co-fractionation Homo sapiens
257 ZNF492  
Affinity Capture-MS Homo sapiens
258 MRPL42  
Affinity Capture-MS Homo sapiens
259 ENY2 56943
Affinity Capture-MS Homo sapiens
260 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
261 RPL3L 6123
Co-fractionation Homo sapiens
262 WDR36 134430
Affinity Capture-MS Homo sapiens
263 RPS25 6230
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
264 PARP1 142
Affinity Capture-MS Homo sapiens
265 BKRF1  
Affinity Capture-MS
266 UBE2O 63893
Affinity Capture-MS Homo sapiens
267 ILF3 3609
Affinity Capture-MS Homo sapiens
268 CUL2 8453
Affinity Capture-MS Homo sapiens
269 FBXL6  
Affinity Capture-MS Homo sapiens
270 TP53 7157
Affinity Capture-MS Homo sapiens
271 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
272 FOLR1 2348
Affinity Capture-MS Homo sapiens
273 ZNF273  
Affinity Capture-MS Homo sapiens
274 MINA 84864
Affinity Capture-MS Homo sapiens
275 ZNF496  
Affinity Capture-MS Homo sapiens
276 ZNF746  
Affinity Capture-MS Homo sapiens
277 USP36  
Affinity Capture-MS Homo sapiens
278 PRRC2C 23215
Cross-Linking-MS (XL-MS) Homo sapiens
279 MRPS31  
Affinity Capture-MS Homo sapiens
280 MRPL18 29074
Affinity Capture-MS Homo sapiens
281 UIMC1  
Affinity Capture-MS Homo sapiens
282 CUL5 8065
Affinity Capture-MS Homo sapiens
283 RPS12 6206
Co-fractionation Homo sapiens
284 RPS4X 6191
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
285 ZNF48  
Affinity Capture-MS Homo sapiens
286 RPS15 6209
Co-fractionation Homo sapiens
287 SRP72 6731
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
288 ICT1 3396
Affinity Capture-MS Homo sapiens
289 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
290 G3BP2 9908
Affinity Capture-MS Homo sapiens
291 EIF4A3 9775
Affinity Capture-MS Homo sapiens
292 MRPS18C  
Affinity Capture-MS Homo sapiens
293 RPS5 6193
Co-fractionation Homo sapiens
294 RPF1  
Affinity Capture-MS Homo sapiens
295 AIMP2 7965
Co-fractionation Homo sapiens
296 RPL34 6164
Co-fractionation Homo sapiens
297 ZNF714  
Affinity Capture-MS Homo sapiens
298 TOP2A 7153
Affinity Capture-MS Homo sapiens
299 ESR1  
Affinity Capture-MS Homo sapiens
300 DRG1 4733
Affinity Capture-MS Homo sapiens
301 UFL1 23376
Affinity Capture-MS Homo sapiens
302 RPL10A 4736
Co-fractionation Homo sapiens
303 RPL38 6169
Co-fractionation Homo sapiens
304 RIOK2 55781
Affinity Capture-MS Homo sapiens
305 NCL 4691
Affinity Capture-MS Homo sapiens
306 SEC61B 10952
Affinity Capture-MS Homo sapiens
307 MRPL13  
Affinity Capture-MS Homo sapiens
308 RPSA 3921
Co-fractionation Homo sapiens
309 TRIP4 9325
Affinity Capture-MS Homo sapiens
310 RPL7A 6130
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
311 PINK1  
Affinity Capture-MS Homo sapiens
312 RBM8A 9939
Affinity Capture-MS Homo sapiens
313 RPS6 6194
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
314 RPL8 6132
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
315 C1QBP 708
Proximity Label-MS Homo sapiens
316 XRCC6 2547
Proximity Label-MS Homo sapiens
317 CUL7 9820
Affinity Capture-MS Homo sapiens
318 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
319 HNRNPU 3192
Affinity Capture-MS Homo sapiens
320 GNB2L1 10399
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
321 AR 367
Affinity Capture-MS Homo sapiens
322 DDX31  
Affinity Capture-MS Homo sapiens
323 RPL36AL 6166
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
324 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
325 MRPL55  
Affinity Capture-MS Homo sapiens
326 GNL3L 54552
Affinity Capture-MS Homo sapiens
327 MRPL28 10573
Affinity Capture-MS Homo sapiens
328 DARS 1615
Co-fractionation Homo sapiens
329 EXOSC1 51013
Affinity Capture-MS Homo sapiens
330 MRPS18A  
Affinity Capture-MS Homo sapiens
331 MRPL32 64983
Affinity Capture-MS Homo sapiens
332 MRPS9 64965
Affinity Capture-MS Homo sapiens
333 RPL17 6139
Co-fractionation Homo sapiens
334 EIF5 1983
Affinity Capture-MS Homo sapiens
335 HNRNPA2B1 3181
Co-fractionation Homo sapiens
336 PARN  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RPL27A is involved
PathwayEvidenceSource
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Post-translational protein modification TAS Reactome
Protein hydroxylation TAS Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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