Gene description for RPL18
Gene name ribosomal protein L18
Gene symbol RPL18
Other names/aliases L18
Species Homo sapiens
 Database cross references - RPL18
ExoCarta ExoCarta_6141
Vesiclepedia VP_6141
Entrez Gene 6141
HGNC 10310
MIM 604179
UniProt Q07020  
 RPL18 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Keratinocytes 19530224    
Keratinocytes 19530224    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPL18
Molecular Function
    RNA binding GO:0003723 IBA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 NAS
    protein binding GO:0005515 IPI
Biological Process
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 IDA
    cytoplasmic translation GO:0002181 NAS
    translation GO:0006412 NAS
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 NAS
    endoplasmic reticulum GO:0005783 IDA
    rough endoplasmic reticulum GO:0005791 IEA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    focal adhesion GO:0005925 HDA
    membrane GO:0016020 HDA
    cytosolic large ribosomal subunit GO:0022625 HDA
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic ribosome GO:0022626 IDA
 Experiment description of studies that identified RPL18 in sEVs
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 494
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 496
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
14
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 234
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
24
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 236
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
26
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
27
Experiment ID 189
MISEV standards
EM
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 190
MISEV standards
EM
Biophysical techniques
HSC70
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 200
MISEV standards
EM
Biophysical techniques
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 254
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 255
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 256
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 257
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 258
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 259
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 260
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
40
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
41
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
45
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
47
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
48
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
49
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
50
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
51
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
52
Experiment ID 275
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
53
Experiment ID 274
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
54
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
55
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
56
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
57
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL18
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF771  
Affinity Capture-MS Homo sapiens
2 UBL4A 8266
Affinity Capture-MS Homo sapiens
3 ZNF346  
Affinity Capture-MS Homo sapiens
4 RIN3  
Affinity Capture-MS Homo sapiens
5 SKI 6497
Affinity Capture-MS Homo sapiens
6 EBNA-LP  
Affinity Capture-MS
7 KIF20A 10112
Affinity Capture-MS Homo sapiens
8 MRPL27 51264
Affinity Capture-MS Homo sapiens
9 NHP2L1 4809
Co-fractionation Homo sapiens
10 UTP3 57050
Affinity Capture-MS Homo sapiens
11 SOX2  
Affinity Capture-MS Homo sapiens
12 MRPS18C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 NOL8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
15 DDA1  
Affinity Capture-MS Homo sapiens
16 KIF23 9493
Affinity Capture-MS Homo sapiens
17 UBE2O 63893
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 METAP2 10988
Affinity Capture-MS Homo sapiens
19 FBL 2091
Co-fractionation Homo sapiens
20 RPS9 6203
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
21 RPF2 84154
Affinity Capture-MS Homo sapiens
22 CENPQ  
Affinity Capture-MS Homo sapiens
23 SFN 2810
Affinity Capture-MS Homo sapiens
24 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 ARIH2 10425
Affinity Capture-MS Homo sapiens
26 RPS11 6205
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
27 MRPL47 57129
Affinity Capture-MS Homo sapiens
28 EEF1A1 1915
Co-fractionation Homo sapiens
29 KIF14 9928
Affinity Capture-MS Homo sapiens
30 EMC9  
Affinity Capture-MS Homo sapiens
31 Cstf2t  
Two-hybrid Mus musculus
32 CHMP4C 92421
Affinity Capture-MS Homo sapiens
33 RRP9 9136
Affinity Capture-MS Homo sapiens
34 RBM4B  
Affinity Capture-MS Homo sapiens
35 DNAJB7  
Affinity Capture-MS Homo sapiens
36 PURG  
Affinity Capture-MS Homo sapiens
37 RPL18A 6142
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
38 TTC19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 PABPC1 26986
Co-fractionation Homo sapiens
40 EEF1E1 9521
Co-fractionation Homo sapiens
41 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 TRIM21 6737
Affinity Capture-MS Homo sapiens
43 SLX4  
Affinity Capture-MS Homo sapiens
44 RPL31 6160
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
45 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
46 HECTD1 25831
Affinity Capture-MS Homo sapiens
47 CUL2 8453
Affinity Capture-MS Homo sapiens
48 MAGEB2 4113
Affinity Capture-MS Homo sapiens
49 GTPBP4 23560
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 SLC25A5 292
Co-fractionation Homo sapiens
51 CNBP 7555
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ANLN 54443
Affinity Capture-MS Homo sapiens
53 HIST1H2AD 3013
Co-fractionation Homo sapiens
54 RBM39 9584
Affinity Capture-MS Homo sapiens
55 DNAJC21  
Affinity Capture-MS Homo sapiens
56 NOC3L 64318
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 MRPL24  
Affinity Capture-MS Homo sapiens
58 MRPL16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 NPM3 10360
Affinity Capture-MS Homo sapiens
60 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 FN1 2335
Affinity Capture-MS Homo sapiens
63 ZNF512  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
64 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
65 PCBP1 5093
Affinity Capture-MS Homo sapiens
66 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
67 RPL35A 6165
Co-fractionation Homo sapiens
68 DDX54 79039
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 PATZ1  
Affinity Capture-MS Homo sapiens
70 GNL3 26354
Affinity Capture-MS Homo sapiens
71 RPS16 6217
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
72 DNAJC28  
Affinity Capture-MS Homo sapiens
73 NUDT21 11051
Co-fractionation Homo sapiens
74 RPS27A 6233
Co-fractionation Homo sapiens
75 RPLP0 6175
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
76 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 NLE1 54475
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 RRP1 8568
Affinity Capture-MS Homo sapiens
79 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
80 G3BP2 9908
Affinity Capture-MS Homo sapiens
81 H2AFB3  
Affinity Capture-MS Homo sapiens
82 RPS15A 6210
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
83 RPS24 6229
Co-fractionation Homo sapiens
84 NCL 4691
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
85 EIF4B 1975
Affinity Capture-MS Homo sapiens
86 ATP5B 506
Co-fractionation Homo sapiens
87 PTGES3 10728
Co-fractionation Homo sapiens
88 HNF1B  
Affinity Capture-MS Homo sapiens
89 MRPL28 10573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 NVL  
Affinity Capture-MS Homo sapiens
91 HERC5 51191
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 MRPL48  
Affinity Capture-MS Homo sapiens
93 SPRTN  
Affinity Capture-MS Homo sapiens
94 EIF2S3 1968
Affinity Capture-MS Homo sapiens
95 KIAA0020 9933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 RPS17 6218
Co-fractionation Homo sapiens
97 RPA2 6118
Affinity Capture-MS Homo sapiens
98 VPRBP 9730
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 URB1 9875
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 NOP56 10528
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
101 RPL14 9045
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
102 CAND1 55832
Affinity Capture-MS Homo sapiens
103 RPS3 6188
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
104 RPS18 6222
Co-fractionation Homo sapiens
105 B3GNT2 10678
Affinity Capture-MS Homo sapiens
106 DDX24 57062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 COPS6 10980
Affinity Capture-MS Homo sapiens
108 PRC1 9055
Affinity Capture-MS Homo sapiens
109 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 RECQL4  
Affinity Capture-MS Homo sapiens
111 OBSL1 23363
Affinity Capture-MS Homo sapiens
112 NSUN4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 PAK1IP1  
Affinity Capture-MS Homo sapiens
114 VCAM1 7412
Affinity Capture-MS Homo sapiens
115 DDX6 1656
Affinity Capture-MS Homo sapiens
116 CUL1 8454
Affinity Capture-MS Homo sapiens
117 RBM42  
Affinity Capture-MS Homo sapiens
118 RRP7A 27341
Affinity Capture-MS Homo sapiens
119 RPL10L 140801
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
120 MRPS35 60488
Affinity Capture-MS Homo sapiens
121 ACTA2 59
Co-fractionation Homo sapiens
122 RHOA 387
Co-fractionation Homo sapiens
123 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
124 DDX21 9188
Affinity Capture-MS Homo sapiens
125 CDKN1A  
Two-hybrid Homo sapiens
126 RPL4 6124
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
127 RBM28 55131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 DRG1 4733
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 VRK1 7443
Affinity Capture-MS Homo sapiens
130 DDX10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 MRPL51 51258
Affinity Capture-MS Homo sapiens
132 REXO4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 MRPL3  
Affinity Capture-MS Homo sapiens
134 LYAR 55646
Affinity Capture-MS Homo sapiens
135 Rrbp1  
Affinity Capture-MS Mus musculus
136 MAGOH 4116
Affinity Capture-MS Homo sapiens
137 IARS 3376
Co-fractionation Homo sapiens
138 RPLP0P6 220717
Co-fractionation Homo sapiens
139 DDX27 55661
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
140 CYLD  
Affinity Capture-MS Homo sapiens
141 KDF1  
Affinity Capture-MS Homo sapiens
142 RSL1D1 26156
Affinity Capture-MS Homo sapiens
143 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
144 RPL32 6161
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
145 ZNF770 54989
Affinity Capture-MS Homo sapiens
146 RPS2 6187
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
147 XPO1 7514
Affinity Capture-MS Homo sapiens
148 RC3H2  
Affinity Capture-MS Homo sapiens
149 MRPL9 65005
Affinity Capture-MS Homo sapiens
150 SRSF5 6430
Affinity Capture-MS Homo sapiens
151 EGFR 1956
Negative Genetic Homo sapiens
152 FAM90A1  
Affinity Capture-MS Homo sapiens
153 FUS 2521
Affinity Capture-MS Homo sapiens
154 HSP90AA5P 730211
Co-fractionation Homo sapiens
155 RPS27 6232
Co-fractionation Homo sapiens
156 CDK2 1017
Affinity Capture-MS Homo sapiens
157 CEP250 11190
Affinity Capture-MS Homo sapiens
158 MYC  
Affinity Capture-MS Homo sapiens
159 BAG1 573
Affinity Capture-MS Homo sapiens
160 CEBPZ  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 SART3 9733
Affinity Capture-MS Homo sapiens
162 CUL7 9820
Affinity Capture-MS Homo sapiens
163 AHNAK2 113146
Cross-Linking-MS (XL-MS) Homo sapiens
164 H2AFB2  
Affinity Capture-MS Homo sapiens
165 CCDC140  
Affinity Capture-MS Homo sapiens
166 RPL26 6154
Co-fractionation Homo sapiens
167 FTSJ3 117246
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 HUWE1 10075
Affinity Capture-MS Homo sapiens
169 RPL19 6143
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
170 PA2G4 5036
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 RPL13 6137
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
172 SURF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 ILF3 3609
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 FOLR1 2348
Affinity Capture-MS Homo sapiens
177 RPS12 6206
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
178 RPS4X 6191
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
179 UTP23  
Affinity Capture-MS Homo sapiens
180 RPS10P5 93144
Co-fractionation Homo sapiens
181 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
182 RPS5 6193
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
183 NIFK 84365
Co-fractionation Homo sapiens
184 RPS26 6231
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
185 NOC2L 26155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 EEF1D 1936
Co-fractionation Homo sapiens
187 RPL7A 6130
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
188 IL7R  
Protein-RNA Homo sapiens
189 ARF1 375
Proximity Label-MS Homo sapiens
190 EIF2AK2 5610
Reconstituted Complex Homo sapiens
191 C1QBP 708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 KRAS 3845
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
193 PRMT1 3276
Affinity Capture-MS Homo sapiens
194 MRPS9 64965
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 ZNF668  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 RPSA 3921
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
197 RPL26L1 51121
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 MRPL17  
Affinity Capture-MS Homo sapiens
199 CD4 920
Affinity Capture-MS Homo sapiens
200 CENPC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 RPS19 6223
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
202 SSB 6741
Cross-Linking-MS (XL-MS) Homo sapiens
203 FAU 2197
Co-fractionation Homo sapiens
204 HNRNPUL2 221092
Co-fractionation Homo sapiens
205 ATG13 9776
Affinity Capture-MS Homo sapiens
206 CAPZB 832
Affinity Capture-MS Homo sapiens
207 RPL10A 4736
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
208 MCM2 4171
Affinity Capture-MS Homo sapiens
209 ZBTB47  
Affinity Capture-MS Homo sapiens
210 DDRGK1 65992
Affinity Capture-MS Homo sapiens
211 ITGA4 3676
Affinity Capture-MS Homo sapiens
212 LOC101929876 101929876
Co-fractionation Homo sapiens
213 DDX18 8886
Affinity Capture-MS Homo sapiens
214 TFCP2 7024
Affinity Capture-MS Homo sapiens
215 PABPC4 8761
Co-fractionation Homo sapiens
216 RBM8A 9939
Affinity Capture-MS Homo sapiens
217 RBM19 9904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 HSPA8 3312
Cross-Linking-MS (XL-MS) Homo sapiens
219 LIN28A  
Affinity Capture-MS Homo sapiens
220 BRIX1 55299
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 NF2 4771
Affinity Capture-MS Homo sapiens
222 RPL27 6155
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
223 ATP5A1 498
Co-fractionation Homo sapiens
224 IPO7 10527
Affinity Capture-MS Homo sapiens
225 RPL9 6133
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
226 CUL4B 8450
Affinity Capture-MS Homo sapiens
227 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
228 RPS10 6204
Co-fractionation Homo sapiens
229 NOP2 4839
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
230 ACACA 31
Positive Genetic Homo sapiens
231 RPL5 6125
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
232 CHMP4B 128866
Affinity Capture-MS Homo sapiens
233 BTF3 689
Affinity Capture-MS Homo sapiens
234 NTRK1 4914
Affinity Capture-MS Homo sapiens
235 U2AF2 11338
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
236 ARNT 405
Affinity Capture-MS Homo sapiens
237 Srp72  
Affinity Capture-MS Mus musculus
238 RPL36 25873
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
239 RPA4  
Proximity Label-MS Homo sapiens
240 RPLP1 6176
Co-fractionation Homo sapiens
241 TUBA1B 10376
Co-fractionation Homo sapiens
242 ENY2 56943
Affinity Capture-MS Homo sapiens
243 MYL12A 10627
Co-fractionation Homo sapiens
244 RPL11 6135
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
245 Brwd3  
Affinity Capture-MS Mus musculus
246 RPL23A 6147
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
247 TNFAIP8L1  
Affinity Capture-MS Homo sapiens
248 METTL14  
Affinity Capture-MS Homo sapiens
249 ECT2 1894
Affinity Capture-MS Homo sapiens
250 EEF2 1938
Co-fractionation Homo sapiens
251 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
252 RPL21 6144
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
253 FNTA 2339
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
254 DHX30 22907
Affinity Capture-MS Homo sapiens
255 PDCD11 22984
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
256 NCAPH 23397
Affinity Capture-MS Homo sapiens
257 PSPC1 55269
Affinity Capture-MS Homo sapiens
258 RPS13 6207
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
259 RPS14 6208
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
260 RPL12 6136
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
261 RPL22 6146
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
262 HP1BP3 50809
Affinity Capture-MS Homo sapiens
263 FNTB 2342
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
265 C3orf17  
Affinity Capture-MS Homo sapiens
266 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
267 RPL3L 6123
Co-fractionation Homo sapiens
268 RPS25 6230
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
269 FANCC 2176
Two-hybrid Homo sapiens
270 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
271 RPS21 6227
Co-fractionation Homo sapiens
272 RPA1 6117
Affinity Capture-MS Homo sapiens
273 HNRNPM 4670
Co-fractionation Homo sapiens
274 G3BP1 10146
Affinity Capture-MS Homo sapiens
275 MRPS10 55173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
276 DDX58 23586
Affinity Capture-RNA Homo sapiens
277 MKI67  
Affinity Capture-MS Homo sapiens
278 MYBBP1A 10514
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
279 RPL34 6164
Co-fractionation Homo sapiens
280 PDZD8 118987
Affinity Capture-MS Homo sapiens
281 UFL1 23376
Affinity Capture-MS Homo sapiens
282 TRIM37  
Proximity Label-MS Homo sapiens
283 RPL38 6169
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
284 API5 8539
Affinity Capture-MS Homo sapiens
285 SEC61B 10952
Affinity Capture-MS Homo sapiens
286 IL17B 27190
Affinity Capture-MS Homo sapiens
287 RPS7 6201
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
288 RPL8 6132
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 RPL28 6158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 RPS27L 51065
Co-fractionation Homo sapiens
291 RBM34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
292 DDX56  
Affinity Capture-MS Homo sapiens
293 GNL2 29889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 UBE2H 7328
Affinity Capture-MS Homo sapiens
295 SRP19 6728
Affinity Capture-MS Homo sapiens
296 RIT1 6016
Negative Genetic Homo sapiens
297 RPS3A 6189
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
298 RPL30 6156
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
299 PPIE 10450
Affinity Capture-MS Homo sapiens
300 RPL13A 23521
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
301 RPL37A 6168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
302 RPL10 6134
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
303 RPL15 6138
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
304 DNAJC25 548645
Affinity Capture-MS Homo sapiens
305 BUD13  
Affinity Capture-MS Homo sapiens
306 ZBTB1  
Affinity Capture-MS Homo sapiens
307 DNAJC15  
Affinity Capture-MS Homo sapiens
308 ILF2 3608
Co-fractionation Homo sapiens
309 GSK3A 2931
Affinity Capture-MS Homo sapiens
310 USP36  
Affinity Capture-MS Homo sapiens
311 MRPS5 64969
Affinity Capture-MS Homo sapiens
312 TOP2A 7153
Affinity Capture-MS Homo sapiens
313 RPS20 6224
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
314 MRPL20 55052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 COPS5 10987
Affinity Capture-MS Homo sapiens
316 FBXW7  
Affinity Capture-MS Homo sapiens
317 RPL24 6152
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
318 MRPS24 64951
Affinity Capture-MS Homo sapiens
319 MRPL12 6182
Co-fractionation Homo sapiens
320 ADARB1 104
Affinity Capture-MS Homo sapiens
321 PRKRA 8575
Affinity Capture-MS Homo sapiens
322 DDX51  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
323 DNAJC16  
Affinity Capture-MS Homo sapiens
324 EED  
Affinity Capture-MS Homo sapiens
325 SRP68 6730
Affinity Capture-MS Homo sapiens
326 ABT1 29777
Affinity Capture-MS Homo sapiens
327 RRP8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
328 NAP1L4 4676
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
329 MYCN  
Affinity Capture-MS Homo sapiens
330 CTCF  
Affinity Capture-MS Homo sapiens
331 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
332 FCF1  
Affinity Capture-MS Homo sapiens
333 RPS23 6228
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
334 SRP9 6726
Affinity Capture-MS Homo sapiens
335 MRPL32 64983
Affinity Capture-MS Homo sapiens
336 STAU1 6780
Affinity Capture-MS Homo sapiens
337 SRSF6 6431
Affinity Capture-MS Homo sapiens
338 ZNF22  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
339 VCP 7415
Affinity Capture-MS Homo sapiens
340 RPL27A 6157
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
341 PML 5371
Affinity Capture-MS Homo sapiens
342 SPTY2D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
343 FGF13  
Affinity Capture-MS Homo sapiens
344 MRPS33  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
345 RPF1  
Affinity Capture-MS Homo sapiens
346 SPPL3  
Affinity Capture-MS Homo sapiens
347 ZNF644  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
348 SEC63 11231
Affinity Capture-MS Homo sapiens
349 RPLP2 6181
Co-fractionation Homo sapiens
350 FANCD2  
Affinity Capture-MS Homo sapiens
351 TRIM31  
Affinity Capture-MS Homo sapiens
352 DNAJC2 27000
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
353 RPL35 11224
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
354 CTNNB1 1499
Affinity Capture-MS Homo sapiens
355 RPS6 6194
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
356 RPL3 6122
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
357 NAP1L1 4673
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
358 RPL7 6129
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
359 ZC3H10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
360 AURKB 9212
Affinity Capture-MS Homo sapiens
361 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
362 DKC1 1736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
363 FBXO6 26270
Affinity Capture-MS Homo sapiens
364 INO80B 83444
Affinity Capture-MS Homo sapiens
365 DYRK2 8445
Affinity Capture-MS Homo sapiens
366 BMP4 652
Affinity Capture-MS Homo sapiens
367 DDX52  
Affinity Capture-MS Homo sapiens
368 GNB2L1 10399
Affinity Capture-MS Homo sapiens
369 MDM2  
Affinity Capture-MS Homo sapiens
370 CCDC8  
Affinity Capture-MS Homo sapiens
371 ARRB2 409
Affinity Capture-MS Homo sapiens
372 SIRT6  
Affinity Capture-MS Homo sapiens
373 DNAJC19 131118
Affinity Capture-MS Homo sapiens
374 MINA 84864
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
375 ZNF746  
Affinity Capture-MS Homo sapiens
376 MRPS31  
Affinity Capture-MS Homo sapiens
377 CUL5 8065
Affinity Capture-MS Homo sapiens
378 ZNF48  
Affinity Capture-MS Homo sapiens
379 RPS15 6209
Co-fractionation Homo sapiens
380 SRP72 6731
Affinity Capture-MS Homo sapiens
381 NSA2  
Affinity Capture-MS Homo sapiens
382 EIF4A3 9775
Affinity Capture-MS Homo sapiens
383 FANCA  
Two-hybrid Homo sapiens
384 RPS28 6234
Co-fractionation Homo sapiens
385 MRPL13  
Affinity Capture-MS Homo sapiens
386 TRIP4 9325
Affinity Capture-MS Homo sapiens
387 RPL23 9349
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
388 PINK1  
Affinity Capture-MS Homo sapiens
389 RPS8 6202
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
390 GRSF1 2926
Proximity Label-MS Homo sapiens
391 DNAJC1 64215
Affinity Capture-MS Homo sapiens
392 HNRNPU 3192
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
393 C9orf72  
Affinity Capture-MS Homo sapiens
394 RPL17 6139
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which RPL18 is involved
PathwayEvidenceSource
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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