Gene ontology annotations for RPL15
Experiment description of studies that identified RPL15 in sEVs
1
Experiment ID
76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20224111
Organism
Homo sapiens
Experiment description
Proteomics analysis of bladder cancer exosomes.
Authors
"Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name
MCP
Publication year
2010
Sample
Bladder cancer cells
Sample name
HT1376
Isolation/purification methods
Differential centrifugation Sucrose density gradient
Flotation density
1.10-1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [MALDI TOF/TOF] Western blotting FACS
2
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
6
Experiment ID
412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MCF7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
7
Experiment ID
414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
8
Experiment ID
426
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
9
Experiment ID
427
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Breast cancer cells
Sample name
MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
10
Experiment ID
494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
Osteoarthritic cartilage
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
11
Experiment ID
496
MISEV standards
✘
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
Healthy cartilage
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
12
Experiment ID
497
MISEV standards
✘
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
13
Experiment ID
498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35931686
Organism
Homo sapiens
Experiment description
Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors
"Varela-EirÃÂn M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, GarcÃÂa-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name
Cell Death Dis
Publication year
2022
Sample
Chondrocytes
Sample name
T/C-28a2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
14
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
15
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
16
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
17
Experiment ID
283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘
Negative markers
✔
DLS
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25890246
Organism
Homo sapiens
Experiment description
Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors
"Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name
Methods
Publication year
2015
Sample
Colorectal cancer cells
Sample name
LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Centrifugal concentration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
18
Experiment ID
407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
19
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
20
Experiment ID
419
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
21
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
22
Experiment ID
420
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Embryonic kidney cells
Sample name
HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
23
Experiment ID
405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Foreskin fibroblasts
Sample name
BJ
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
24
Experiment ID
363
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
25
Experiment ID
364
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
26
Experiment ID
365
MISEV standards
✘
Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
33991177
Organism
Homo sapiens
Experiment description
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors
"Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name
Proteomics
Publication year
2021
Sample
Gastric cancer cells
Sample name
MKN1 - 100K pellet
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
27
Experiment ID
234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-C3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
28
Experiment ID
235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
29
Experiment ID
236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
30
Experiment ID
237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
31
Experiment ID
417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Lymphoma cells
Sample name
Raji
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
32
Experiment ID
411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Mammary cancer-associated fibroblasts
Sample name
mCAF
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
33
Experiment ID
254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
MNT-1
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
34
Experiment ID
255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
G1
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
35
Experiment ID
256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
501mel
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
36
Experiment ID
257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
Daju
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
37
Experiment ID
258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
SKMEL28
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
38
Experiment ID
259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
A375M
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
39
Experiment ID
260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
"Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
1205Lu
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
40
Experiment ID
126
MISEV standards
✘
Biophysical techniques
✔
GAPDH
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry [LTQ-FT Ultra]
PubMed ID
Unpublished / Not applicable
Organism
Homo sapiens
Experiment description
Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors
"Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name
Mesenchymal Stem Cell Therapy
Publication year
2011
Sample
Mesenchymal stem cells
Sample name
huES9.E1
Isolation/purification methods
HPLC
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Antobody array Mass spectrometry
41
Experiment ID
488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Homo sapiens
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Mesenchymal stem cells
Sample name
UCMSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
42
Experiment ID
418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Monocytic leukemia cells
Sample name
THP-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
43
Experiment ID
418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Monocytic leukemia cells
Sample name
THP-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
44
Experiment ID
224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
"Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
45
Experiment ID
413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Normal mammary epithelial cells
Sample name
MCF10A
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
46
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
47
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
48
Experiment ID
406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
BxPC3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
49
Experiment ID
415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
50
Experiment ID
434
MISEV standards
✘
Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Size exclusion chromatography
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
51
Experiment ID
435
MISEV standards
✘
Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic cancer cells
Sample name
PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation OptiPrep density gradient centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
52
Experiment ID
408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPDE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
53
Experiment ID
409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pancreatic duct epithalial cells
Sample name
HPNE
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
54
Experiment ID
416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
Pluripotent stem cells
Sample name
PSC
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
55
Experiment ID
834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
56
Experiment ID
835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
35333565
Organism
Homo sapiens
Experiment description
LAMP2A regulates the loading of proteins into exosomes
Authors
"Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name
Sci Adv
Publication year
2022
Sample
Retinal pigment epithelial cells
Sample name
ARPE-19
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
57
Experiment ID
191
MISEV standards
✘
Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
"Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
58
Experiment ID
410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
34108659
Organism
Homo sapiens
Experiment description
Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors
"Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name
Nat Cell Biol
Publication year
2021
Sample
T lymphocytes
Sample name
Jurkat
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein mRNA
Methods used in the study
RT-qPCR Western blotting Mass spectrometry Flow cytometry
59
Experiment ID
217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
"Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for RPL15
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
TRMT1L
81627
Affinity Capture-MS
Homo sapiens
2
UBL4A
8266
Affinity Capture-MS
Homo sapiens
3
ZNF346
Affinity Capture-MS
Homo sapiens
4
SRPK2
6733
Affinity Capture-MS
Homo sapiens
5
DYNC1I2
1781
Proximity Label-MS
Homo sapiens
6
KIF20A
10112
Affinity Capture-MS
Homo sapiens
7
NHP2L1
4809
Co-fractionation
Homo sapiens
8
PNMAL1
Affinity Capture-MS
Homo sapiens
9
SOX2
Affinity Capture-MS
Homo sapiens
10
RIOK1
83732
Affinity Capture-MS
Homo sapiens
11
NOL8
Affinity Capture-MS
Homo sapiens
12
CUL7
9820
Affinity Capture-MS
Homo sapiens
13
CENPU
Affinity Capture-MS
Homo sapiens
14
GPATCH4
54865
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
15
DDA1
Affinity Capture-MS
Homo sapiens
16
WHSC1
7468
Proximity Label-MS
Homo sapiens
17
DARS
1615
Co-fractionation
Homo sapiens
18
DNAJC19
131118
Affinity Capture-MS
Homo sapiens
19
KIF23
9493
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
20
UBE2O
63893
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
21
METAP2
10988
Affinity Capture-MS
Homo sapiens
22
FBL
2091
Co-fractionation
Homo sapiens
23
ARMCX3
51566
Affinity Capture-MS
Homo sapiens
24
RPS9
6203
Co-fractionation
Homo sapiens
25
RPF2
84154
Affinity Capture-MS
Homo sapiens
26
NSMCE4A
Affinity Capture-MS
Homo sapiens
27
POLR2C
5432
Proximity Label-MS
Homo sapiens
28
MECP2
4204
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
29
ARIH2
10425
Affinity Capture-MS
Homo sapiens
30
RPS11
6205
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
31
EEF1A1
1915
Co-fractionation
Homo sapiens
32
KIF14
9928
Affinity Capture-MS
Homo sapiens
33
CLASP2
23122
Affinity Capture-MS
Homo sapiens
34
EMC9
Affinity Capture-MS
Homo sapiens
35
CHMP4C
92421
Affinity Capture-MS
Homo sapiens
36
TARBP2
Affinity Capture-MS
Homo sapiens
37
RBM4B
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
38
TUFM
7284
Co-fractionation
Homo sapiens
39
RPL18A
6142
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
40
PABPC1
26986
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
41
EEF1E1
9521
Co-fractionation
Homo sapiens
42
TRIM21
6737
Affinity Capture-MS
Homo sapiens
43
RPL31
6160
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
44
GTF3C2
Affinity Capture-MS
Homo sapiens
45
MEOX2
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
46
YWHAQ
10971
Reconstituted Complex
Homo sapiens
47
CENPC
Affinity Capture-MS
Homo sapiens
48
ZRSR2
Affinity Capture-MS
Homo sapiens
49
CUL2
8453
Affinity Capture-MS
Homo sapiens
50
SRPK3
Affinity Capture-MS
Homo sapiens
51
MAGEB2
4113
Affinity Capture-MS
Homo sapiens
52
SEC61B
10952
Affinity Capture-MS
Homo sapiens
53
SRPK1
6732
Affinity Capture-MS
Homo sapiens
54
U2SURP
23350
Affinity Capture-MS
Homo sapiens
55
PIPSL
266971
Affinity Capture-MS
Homo sapiens
56
SLC25A5
292
Co-fractionation
Homo sapiens
57
CD3EAP
Proximity Label-MS
Homo sapiens
58
CNBP
7555
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
59
ANLN
54443
Affinity Capture-MS
Homo sapiens
60
GTF3C3
9330
Affinity Capture-MS
Homo sapiens
61
ABT1
29777
Affinity Capture-MS
Homo sapiens
62
SIRT7
Affinity Capture-MS
Homo sapiens
63
NPM3
10360
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
64
ACTBL2
345651
Affinity Capture-MS
Homo sapiens
65
Fbxl16
Affinity Capture-MS
Mus musculus
66
EBNA1BP2
10969
Affinity Capture-MS
Homo sapiens
67
RPL7L1
285855
Affinity Capture-MS
Homo sapiens
68
EIF2S2
8894
Co-fractionation
Homo sapiens
69
NIP7
51388
Affinity Capture-MS
Homo sapiens
70
FN1
2335
Affinity Capture-MS
Homo sapiens
71
ZNF512
Affinity Capture-MS
Homo sapiens
72
PRMT5
10419
Affinity Capture-MS
Homo sapiens
73
PCBP1
5093
Affinity Capture-MS
Homo sapiens
74
RPA3
6119
Affinity Capture-MS
Homo sapiens
Proximity Label-MS
Homo sapiens
75
MAGEB10
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
76
ZNF692
Affinity Capture-MS
Homo sapiens
77
ZMYND8
23613
Affinity Capture-MS
Homo sapiens
78
RPL35A
6165
Co-fractionation
Homo sapiens
79
DDX54
79039
Affinity Capture-MS
Homo sapiens
80
ZNF687
Affinity Capture-MS
Homo sapiens
81
SPATA5
166378
Affinity Capture-MS
Homo sapiens
82
ZFP62
Affinity Capture-MS
Homo sapiens
83
ASH1L
55870
Affinity Capture-MS
Homo sapiens
84
RPS15A
6210
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
85
GNL3
26354
Co-fractionation
Homo sapiens
86
DDX55
Affinity Capture-MS
Homo sapiens
87
RPS16
6217
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
88
WDR77
79084
Affinity Capture-MS
Homo sapiens
89
RPS27A
6233
Co-fractionation
Homo sapiens
90
RPLP0
6175
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
91
RRS1
23212
Affinity Capture-MS
Homo sapiens
92
NLE1
54475
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
93
LCK
3932
Proximity Label-MS
Homo sapiens
94
CAPZB
832
Affinity Capture-MS
Homo sapiens
95
G3BP2
9908
Affinity Capture-MS
Homo sapiens
96
SPTY2D1
Affinity Capture-MS
Homo sapiens
97
PWP1
11137
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
98
KRR1
11103
Affinity Capture-MS
Homo sapiens
99
RPS24
6229
Co-fractionation
Homo sapiens
100
NCL
4691
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
101
PPAN
56342
Affinity Capture-MS
Homo sapiens
102
PURA
5813
Affinity Capture-MS
Homo sapiens
103
NVL
Affinity Capture-MS
Homo sapiens
104
H1FOO
132243
Affinity Capture-MS
Homo sapiens
105
HERC5
51191
Affinity Capture-MS
Homo sapiens
106
KIAA0020
9933
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
107
RSL24D1
Affinity Capture-MS
Homo sapiens
108
TARDBP
23435
Affinity Capture-MS
Homo sapiens
109
RPA2
6118
Affinity Capture-MS
Homo sapiens
110
VPRBP
9730
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
111
URB1
9875
Affinity Capture-MS
Homo sapiens
112
NOP56
10528
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
113
RPL14
9045
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
114
URB2
Affinity Capture-MS
Homo sapiens
115
CAND1
55832
Affinity Capture-MS
Homo sapiens
116
RSBN1
Affinity Capture-MS
Homo sapiens
117
RBM34
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
118
PWP2
5822
Affinity Capture-MS
Homo sapiens
119
RPS3
6188
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
120
DNAJB6
10049
Affinity Capture-MS
Homo sapiens
121
RPS18
6222
Co-fractionation
Homo sapiens
122
PRR11
Affinity Capture-MS
Homo sapiens
123
B3GNT2
10678
Affinity Capture-MS
Homo sapiens
124
DDX24
57062
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
125
COPS6
10980
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
126
RRP12
23223
Affinity Capture-MS
Homo sapiens
127
PRC1
9055
Affinity Capture-MS
Homo sapiens
128
NPM1
4869
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
129
RECQL4
Affinity Capture-MS
Homo sapiens
130
OBSL1
23363
Affinity Capture-MS
Homo sapiens
131
NSUN4
Affinity Capture-MS
Homo sapiens
132
U2AF1
7307
Co-fractionation
Homo sapiens
133
TRIM25
7706
Affinity Capture-MS
Homo sapiens
134
CUL1
8454
Affinity Capture-MS
Homo sapiens
135
DHX36
170506
Affinity Capture-MS
Homo sapiens
136
RPL10L
140801
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
137
PHF10
Affinity Capture-MS
Homo sapiens
138
CDH1
999
Proximity Label-MS
Homo sapiens
139
HIST1H4A
8359
Affinity Capture-MS
Homo sapiens
140
DDX21
9188
Affinity Capture-MS
Homo sapiens
141
RPL4
6124
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
142
RBM28
55131
Affinity Capture-MS
Homo sapiens
143
DRG1
4733
Affinity Capture-MS
Homo sapiens
144
VRK1
7443
Affinity Capture-MS
Homo sapiens
145
TSPYL5
Affinity Capture-MS
Homo sapiens
146
DDX10
Affinity Capture-MS
Homo sapiens
147
REXO4
Affinity Capture-MS
Homo sapiens
148
LUC7L2
51631
Co-fractionation
Homo sapiens
149
LYAR
55646
Affinity Capture-MS
Homo sapiens
150
RPS6
6194
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
151
MAGOH
4116
Affinity Capture-MS
Homo sapiens
152
IARS
3376
Co-fractionation
Homo sapiens
153
RPLP0P6
220717
Co-fractionation
Homo sapiens
154
CYLD
Affinity Capture-MS
Homo sapiens
155
ASB18
Affinity Capture-MS
Homo sapiens
156
KDF1
Affinity Capture-MS
Homo sapiens
157
PPAN-P2RY11
Affinity Capture-MS
Homo sapiens
158
RPL32
6161
Co-fractionation
Homo sapiens
159
MAP7
9053
Affinity Capture-MS
Homo sapiens
160
RPS2
6187
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
161
RC3H2
Affinity Capture-MS
Homo sapiens
162
TAF1B
Affinity Capture-MS
Homo sapiens
163
EGFR
1956
Negative Genetic
Homo sapiens
164
FAM90A1
Affinity Capture-MS
Homo sapiens
165
RPS27
6232
Co-fractionation
Homo sapiens
166
CEP250
11190
Affinity Capture-MS
Homo sapiens
167
MYC
Affinity Capture-MS
Homo sapiens
168
BAG1
573
Affinity Capture-MS
Homo sapiens
169
CEBPZ
Affinity Capture-MS
Homo sapiens
170
ZCCHC6
79670
Affinity Capture-MS
Homo sapiens
171
RPL23A
6147
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
172
DDRGK1
65992
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
173
RHOB
388
Proximity Label-MS
Homo sapiens
174
RPL26
6154
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
175
FTSJ3
117246
Affinity Capture-MS
Homo sapiens
176
HUWE1
10075
Affinity Capture-MS
Homo sapiens
177
AIMP1
9255
Co-fractionation
Homo sapiens
178
RPL19
6143
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
179
PA2G4
5036
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
180
RPL13
6137
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
181
SURF6
Affinity Capture-MS
Homo sapiens
182
RNF151
Affinity Capture-MS
Homo sapiens
183
PDGFB
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
184
ILF3
3609
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
185
TP53
7157
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
186
FOLR1
2348
Affinity Capture-MS
Homo sapiens
187
SPP1
6696
Two-hybrid
Homo sapiens
188
SRP19
6728
Affinity Capture-MS
Homo sapiens
189
RPS4X
6191
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
190
RPS10P5
93144
Co-fractionation
Homo sapiens
191
TSPYL1
7259
Affinity Capture-MS
Homo sapiens
192
RPS5
6193
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
193
NIFK
84365
Co-fractionation
Homo sapiens
194
RPS26
6231
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
195
ZNF195
Affinity Capture-MS
Homo sapiens
196
NOC2L
26155
Affinity Capture-MS
Homo sapiens
197
EEF1D
1936
Co-fractionation
Homo sapiens
198
RPL7A
6130
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
199
IL7R
Protein-RNA
Homo sapiens
200
C1QBP
708
Affinity Capture-MS
Homo sapiens
201
TOPORS
Affinity Capture-MS
Homo sapiens
202
KRAS
3845
Affinity Capture-MS
Homo sapiens
Negative Genetic
Homo sapiens
203
VASN
114990
Co-fractionation
Homo sapiens
204
TEX10
54881
Affinity Capture-MS
Homo sapiens
205
CUL4A
8451
Affinity Capture-MS
Homo sapiens
206
UBE2H
7328
Affinity Capture-MS
Homo sapiens
207
SENP3
26168
Affinity Capture-MS
Homo sapiens
208
RPL26L1
51121
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
209
MARCKS
4082
Proximity Label-MS
Homo sapiens
210
COPRS
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
211
SDAD1
Affinity Capture-MS
Homo sapiens
212
RPS19
6223
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
213
SRSF8
10929
Affinity Capture-MS
Homo sapiens
214
ATG13
9776
Affinity Capture-MS
Homo sapiens
215
DIMT1
27292
Affinity Capture-MS
Homo sapiens
216
RPL10A
4736
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
217
LLPH
Affinity Capture-MS
Homo sapiens
218
MCM2
4171
Affinity Capture-MS
Homo sapiens
219
CDK12
51755
Affinity Capture-MS
Homo sapiens
220
DUSP11
Affinity Capture-MS
Homo sapiens
221
ZSWIM8
23053
Affinity Capture-MS
Homo sapiens
222
LOC101929876
101929876
Co-fractionation
Homo sapiens
223
PABPC4
8761
Co-fractionation
Homo sapiens
224
RBM8A
9939
Affinity Capture-MS
Homo sapiens
225
RBM19
9904
Affinity Capture-MS
Homo sapiens
226
LIN28A
Affinity Capture-MS
Homo sapiens
227
PSME3
10197
Affinity Capture-MS
Homo sapiens
228
BRIX1
55299
Affinity Capture-MS
Homo sapiens
229
NF2
4771
Affinity Capture-MS
Homo sapiens
230
RPL27
6155
Co-fractionation
Homo sapiens
231
MYO18A
399687
Affinity Capture-MS
Homo sapiens
232
IPO7
10527
Affinity Capture-MS
Homo sapiens
233
RPL9
6133
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
234
CUL4B
8450
Affinity Capture-MS
Homo sapiens
235
PARK2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
236
ZC3H3
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
237
RPS10
6204
Co-fractionation
Homo sapiens
238
CLNS1A
1207
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
239
RPL5
6125
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
240
NOP2
4839
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
241
MCM10
55388
Affinity Capture-MS
Homo sapiens
242
CHMP4B
128866
Affinity Capture-MS
Homo sapiens
243
BTF3
689
Affinity Capture-MS
Homo sapiens
244
NTRK1
4914
Affinity Capture-MS
Homo sapiens
245
HIST1H1E
3008
Affinity Capture-MS
Homo sapiens
246
Srp72
Affinity Capture-MS
Mus musculus
247
RPL36
25873
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
248
RPA4
Proximity Label-MS
Homo sapiens
249
DHFRL1
Proximity Label-MS
Homo sapiens
250
ENY2
56943
Affinity Capture-MS
Homo sapiens
251
NKTR
Affinity Capture-MS
Homo sapiens
252
MYBBP1A
10514
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
253
RPL11
6135
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
254
METTL14
Affinity Capture-MS
Homo sapiens
255
ECT2
1894
Affinity Capture-MS
Homo sapiens
256
YTHDC2
64848
Affinity Capture-MS
Homo sapiens
257
U2AF2
11338
Co-fractionation
Homo sapiens
258
RPL21
6144
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
259
FNTA
2339
Affinity Capture-MS
Homo sapiens
260
ACE2
59272
Affinity Capture-MS
Homo sapiens
261
PDCD11
22984
Affinity Capture-MS
Homo sapiens
262
SAP30
8819
Affinity Capture-MS
Homo sapiens
263
NCAPH
23397
Affinity Capture-MS
Homo sapiens
264
PSPC1
55269
Affinity Capture-MS
Homo sapiens
265
RPS13
6207
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
266
ZC3H18
Affinity Capture-MS
Homo sapiens
267
RPS14
6208
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
268
RPL12
6136
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
269
RPL22
6146
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
270
ACTB
60
Affinity Capture-MS
Homo sapiens
271
RPLP1
6176
Co-fractionation
Homo sapiens
272
RPL18
6141
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
273
RNF2
Affinity Capture-MS
Homo sapiens
274
ZC3HAV1
56829
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
275
Eif3e
16341
Affinity Capture-MS
Mus musculus
276
EIF2S1
1965
Co-fractionation
Homo sapiens
277
ZNF624
57547
Affinity Capture-MS
Homo sapiens
278
PLEKHA4
57664
Affinity Capture-MS
Homo sapiens
279
RPL3L
6123
Co-fractionation
Homo sapiens
280
RPS25
6230
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
281
FBXL6
Affinity Capture-MS
Homo sapiens
282
RPL6
6128
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
283
RPS21
6227
Co-fractionation
Homo sapiens
284
KLHDC3
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
285
RPA1
6117
Affinity Capture-MS
Homo sapiens
286
EFNA1
Affinity Capture-MS
Homo sapiens
287
G3BP1
10146
Affinity Capture-MS
Homo sapiens
288
MKI67
Affinity Capture-MS
Homo sapiens
289
RPL34
6164
Co-fractionation
Homo sapiens
290
PDZD8
118987
Affinity Capture-MS
Homo sapiens
291
UFL1
23376
Affinity Capture-MS
Homo sapiens
292
RPL38
6169
Co-fractionation
Homo sapiens
293
API5
8539
Affinity Capture-MS
Homo sapiens
294
GTPBP4
23560
Affinity Capture-MS
Homo sapiens
295
GLI4
Affinity Capture-MS
Homo sapiens
296
RPS7
6201
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
297
RPL8
6132
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
298
TAF1C
Affinity Capture-MS
Homo sapiens
299
RPS27L
51065
Co-fractionation
Homo sapiens
300
SERBP1
26135
Affinity Capture-MS
Homo sapiens
301
RPL36AL
6166
Affinity Capture-MS
Homo sapiens
302
RC3H1
149041
Affinity Capture-MS
Homo sapiens
303
ATXN3
4287
Affinity Capture-MS
Homo sapiens
304
GNL2
29889
Affinity Capture-MS
Homo sapiens
305
RPSA
3921
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
306
ZBTB38
253461
Affinity Capture-MS
Homo sapiens
307
RPS12
6206
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
308
RIT1
6016
Negative Genetic
Homo sapiens
309
NOLC1
9221
Co-fractionation
Homo sapiens
310
QARS
5859
Co-fractionation
Homo sapiens
311
COIL
Proximity Label-MS
Homo sapiens
312
RPS3A
6189
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
313
ZNF714
Affinity Capture-MS
Homo sapiens
314
RPL30
6156
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
315
PPIE
10450
Affinity Capture-MS
Homo sapiens
316
FAM192A
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
317
RPL13A
23521
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
318
RPL37A
6168
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
319
DHX8
1659
Affinity Capture-MS
Homo sapiens
320
RPL10
6134
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
321
DNAJC25
548645
Affinity Capture-MS
Homo sapiens
322
DHX57
90957
Affinity Capture-MS
Homo sapiens
323
DNAJC15
Affinity Capture-MS
Homo sapiens
324
ILF2
3608
Affinity Capture-MS
Homo sapiens
325
GSK3A
2931
Two-hybrid
Homo sapiens
326
USP36
Affinity Capture-MS
Homo sapiens
327
EIF4ENIF1
56478
Two-hybrid
Homo sapiens
328
TOP2A
7153
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
329
RPS20
6224
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
330
RPL24
6152
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
331
SPECC1L
23384
Affinity Capture-MS
Homo sapiens
332
COPS5
10987
Affinity Capture-MS
Homo sapiens
333
FBXW7
Affinity Capture-MS
Homo sapiens
334
IMPDH2
3615
Co-fractionation
Homo sapiens
335
H2AFY2
55506
Affinity Capture-MS
Homo sapiens
336
ADARB1
104
Affinity Capture-MS
Homo sapiens
337
TTF1
Affinity Capture-MS
Homo sapiens
338
PRKRA
8575
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
339
DDX51
Affinity Capture-MS
Homo sapiens
340
DNAJC16
Affinity Capture-MS
Homo sapiens
341
SRP68
6730
Affinity Capture-MS
Homo sapiens
342
RRP8
Affinity Capture-MS
Homo sapiens
343
SPHK2
56848
Affinity Capture-MS
Homo sapiens
344
SPATA5L1
79029
Affinity Capture-MS
Homo sapiens
345
RAB35
11021
Proximity Label-MS
Homo sapiens
346
MYCN
Affinity Capture-MS
Homo sapiens
347
NEDD8
4738
Affinity Capture-MS
Homo sapiens
348
CCDC86
Affinity Capture-MS
Homo sapiens
349
SETD8
Affinity Capture-MS
Homo sapiens
350
RPS23
6228
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
351
TRIM41
90933
Affinity Capture-MS
Homo sapiens
352
SRP9
6726
Affinity Capture-MS
Homo sapiens
353
STAU1
6780
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
354
IFI16
3428
Affinity Capture-MS
Homo sapiens
355
DICER1
Affinity Capture-MS
Homo sapiens
356
RPL27A
6157
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
357
SMC1A
8243
Cross-Linking-MS (XL-MS)
Homo sapiens
358
PML
5371
Affinity Capture-MS
Homo sapiens
359
H2AFY
9555
Affinity Capture-MS
Homo sapiens
360
FGF13
Affinity Capture-MS
Homo sapiens
361
RPF1
Affinity Capture-MS
Homo sapiens
362
CCDC59
Affinity Capture-MS
Homo sapiens
363
ASH2L
9070
Affinity Capture-MS
Homo sapiens
364
RBM5
Affinity Capture-MS
Homo sapiens
365
BMS1
Affinity Capture-MS
Homo sapiens
366
RPLP2
6181
Co-fractionation
Homo sapiens
367
FANCD2
Affinity Capture-MS
Homo sapiens
368
CUL3
8452
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
369
RPL23
9349
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
370
OTUD1
220213
Affinity Capture-MS
Homo sapiens
371
PANX1
24145
Proximity Label-MS
Homo sapiens
372
DNAJC2
27000
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
373
RPL35
11224
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Cross-Linking-MS (XL-MS)
Homo sapiens
374
TSPYL2
Affinity Capture-MS
Homo sapiens
375
RLIM
51132
Affinity Capture-MS
Homo sapiens
376
SRSF1
6426
Affinity Capture-MS
Homo sapiens
377
Rrbp1
Affinity Capture-MS
Mus musculus
378
RPL3
6122
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
379
NAP1L1
4673
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
380
BBX
56987
Affinity Capture-MS
Homo sapiens
381
RPL7
6129
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
382
ZC3H10
Affinity Capture-MS
Homo sapiens
383
AURKB
9212
Affinity Capture-MS
Homo sapiens
384
GTF3C6
Affinity Capture-MS
Homo sapiens
385
DCUN1D1
54165
Affinity Capture-MS
Homo sapiens
386
DKC1
1736
Affinity Capture-MS
Homo sapiens
387
MDM4
Affinity Capture-MS
Homo sapiens
388
NOL6
65083
Affinity Capture-MS
Homo sapiens
389
GNB2L1
10399
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
390
MDM2
Biochemical Activity
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
391
DNAJC13
23317
Affinity Capture-MS
Homo sapiens
392
EXOSC10
5394
Affinity Capture-MS
Homo sapiens
393
ZNF707
Affinity Capture-MS
Homo sapiens
394
ARRB2
409
Affinity Capture-MS
Homo sapiens
395
ZRANB2
9406
Affinity Capture-MS
Homo sapiens
396
CUL5
8065
Affinity Capture-MS
Homo sapiens
397
ZNF48
Affinity Capture-MS
Homo sapiens
398
RPS15
6209
Co-fractionation
Homo sapiens
399
NSA2
Affinity Capture-MS
Homo sapiens
400
EIF4A3
9775
Affinity Capture-MS
Homo sapiens
401
RPS28
6234
Co-fractionation
Homo sapiens
402
RBM4
5936
Affinity Capture-MS
Homo sapiens
403
ARRB1
408
Two-hybrid
Homo sapiens
404
TRIM31
Affinity Capture-MS
Homo sapiens
405
RPS8
6202
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
406
DNAJC1
64215
Affinity Capture-MS
Homo sapiens
407
HNRNPU
3192
Affinity Capture-MS
Homo sapiens
408
C9orf72
Affinity Capture-MS
Homo sapiens
409
CUEDC1
404093
Affinity Capture-MS
Homo sapiens
410
RPL17
6139
Co-fractionation
Homo sapiens
Co-fractionation
Homo sapiens
View the network
image/svg+xml
Pathways in which RPL15 is involved