Gene description for RPS20
Gene name ribosomal protein S20
Gene symbol RPS20
Other names/aliases S20
Species Homo sapiens
 Database cross references - RPS20
ExoCarta ExoCarta_6224
Vesiclepedia VP_6224
Entrez Gene 6224
HGNC 10405
MIM 603682
UniProt P60866  
 RPS20 identified in exosomes derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for RPS20
Molecular Function
    RNA binding GO:0003723 HDA
    structural constituent of ribosome GO:0003735 HDA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 NAS
    protein binding GO:0005515 IPI
    MDM2/MDM4 family protein binding GO:0097371 IPI
    ubiquitin ligase inhibitor activity GO:1990948 IDA
Biological Process
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    translation GO:0006412 IC
    translation GO:0006412 NAS
    positive regulation of signal transduction by p53 class mediator GO:1901798 IDA
Subcellular Localization
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    cytosolic ribosome GO:0022626 IDA
    cytosolic small ribosomal subunit GO:0022627 HDA
    cytosolic small ribosomal subunit GO:0022627 IBA
    cytosolic small ribosomal subunit GO:0022627 IDA
    cytosolic small ribosomal subunit GO:0022627 NAS
    synapse GO:0045202 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified RPS20 in exosomes
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
13
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
16
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
17
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
21
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
31
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
32
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
33
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
36
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
38
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
40
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
47
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
48
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
49
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
50
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPS20
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
2 SPATS2  
Proximity Label-MS Homo sapiens
3 SECISBP2  
Proximity Label-MS Homo sapiens
4 UBL4A 8266
Affinity Capture-MS Homo sapiens
5 EIF3C 8663
Proximity Label-MS Homo sapiens
6 TTC4  
Co-fractionation Homo sapiens
7 TOP3B 8940
Proximity Label-MS Homo sapiens
8 MAP4 4134
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
9 KIF20A 10112
Affinity Capture-MS Homo sapiens
10 UBC 7316
Affinity Capture-MS Homo sapiens
11 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
12 EIF4E2  
Proximity Label-MS Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
14 APEX1 328
Affinity Capture-RNA Homo sapiens
15 CCDC43 124808
Proximity Label-MS Homo sapiens
16 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
17 KIF23 9493
Affinity Capture-MS Homo sapiens
18 NDRG1 10397
Affinity Capture-MS Homo sapiens
19 GNS 2799
Co-fractionation Homo sapiens
20 METAP2 10988
Affinity Capture-MS Homo sapiens
21 PSMB6 5694
Co-fractionation Homo sapiens
22 RPS9 6203
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
23 GSPT1 2935
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
24 EIF3E 3646
Co-fractionation Homo sapiens
25 SFN 2810
Affinity Capture-MS Homo sapiens
26 ZNF598 90850
Proximity Label-MS Homo sapiens
27 LYN 4067
Proximity Label-MS Homo sapiens
28 MECP2 4204
Affinity Capture-MS Homo sapiens
29 ARIH2 10425
Affinity Capture-MS Homo sapiens
30 RPS11 6205
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
31 RPL19 6143
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
32 RBM14 10432
Affinity Capture-MS Homo sapiens
33 KIF14 9928
Affinity Capture-MS Homo sapiens
34 EMC9  
Affinity Capture-MS Homo sapiens
35 AGO2 27161
Affinity Capture-RNA Homo sapiens
36 CHMP4C 92421
Affinity Capture-MS Homo sapiens
37 TCP1 6950
Co-fractionation Homo sapiens
38 ANKRD17 26057
Proximity Label-MS Homo sapiens
39 YBX2 51087
Affinity Capture-MS Homo sapiens
40 TUFM 7284
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
41 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
42 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
43 RPL18A 6142
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
44 PABPC1 26986
Proximity Label-MS Homo sapiens
45 TRIM21 6737
Affinity Capture-MS Homo sapiens
46 SLX4  
Affinity Capture-MS Homo sapiens
47 RPL31 6160
Co-fractionation Homo sapiens
48 RAD1  
Affinity Capture-MS Homo sapiens
49 SYNCRIP 10492
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
50 ASCC2 84164
Proximity Label-MS Homo sapiens
51 HIST1H1C 3006
Cross-Linking-MS (XL-MS) Homo sapiens
52 CUL2 8453
Affinity Capture-MS Homo sapiens
53 SND1 27044
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
54 SEC61B 10952
Affinity Capture-MS Homo sapiens
55 ANLN 54443
Affinity Capture-MS Homo sapiens
56 MRPL14 64928
Co-fractionation Homo sapiens
57 EIF3G 8666
Proximity Label-MS Homo sapiens
58 HSPA5 3309
Cross-Linking-MS (XL-MS) Homo sapiens
59 RBM39 9584
Affinity Capture-MS Homo sapiens
60 HBS1L 10767
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
61 NPM3 10360
Affinity Capture-MS Homo sapiens
62 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 WIBG 84305
Co-fractionation Homo sapiens
64 FN1 2335
Affinity Capture-MS Homo sapiens
65 STRAP 11171
Proximity Label-MS Homo sapiens
66 HIST1H1B 3009
Affinity Capture-MS Homo sapiens
67 EIF3CL 728689
Co-fractionation Homo sapiens
68 PCBP1 5093
Proximity Label-MS Homo sapiens
69 RPL17 6139
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
70 RPA3 6119
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
71 LTV1  
Proximity Label-MS Homo sapiens
72 RPL35A 6165
Co-fractionation Homo sapiens
73 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
74 CSDE1 7812
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
75 SCAPER  
Proximity Label-MS Homo sapiens
76 GCN1L1 10985
Proximity Label-MS Homo sapiens
77 RPS16 6217
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
78 YBX1 4904
Proximity Label-MS Homo sapiens
79 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
80 PDE4B  
Protein-RNA Homo sapiens
81 GRB2 2885
Affinity Capture-MS Homo sapiens
82 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 CAPZB 832
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
84 G3BP2 9908
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
85 RPS24 6229
Co-fractionation Homo sapiens
86 NCL 4691
Affinity Capture-MS Homo sapiens
87 EIF4B 1975
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
88 CYLD  
Affinity Capture-MS Homo sapiens
89 FAM50A 9130
Cross-Linking-MS (XL-MS) Homo sapiens
90 ACO2 50
Affinity Capture-MS Homo sapiens
91 NFX1  
Proximity Label-MS Homo sapiens
92 RPL23A 6147
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
93 PHF8  
Proximity Label-MS Homo sapiens
94 COL6A3 1293
Cross-Linking-MS (XL-MS) Homo sapiens
95 SPRTN  
Affinity Capture-MS Homo sapiens
96 KRT6B 3854
Proximity Label-MS Homo sapiens
97 EIF2S3 1968
Affinity Capture-MS Homo sapiens
98 RPS17 6218
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
99 TARDBP 23435
Affinity Capture-MS Homo sapiens
100 FMR1 2332
Proximity Label-MS Homo sapiens
101 BTF3 689
Affinity Capture-MS Homo sapiens
102 USP16  
Proximity Label-MS Homo sapiens
103 RPL14 9045
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
104 RIOK3 8780
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
105 CAND1 55832
Affinity Capture-MS Homo sapiens
106 RPS3 6188
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
107 RPS18 6222
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
108 PGK1 5230
Cross-Linking-MS (XL-MS) Homo sapiens
109 B3GNT2 10678
Affinity Capture-MS Homo sapiens
110 HSP90AA1 3320
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
111 HELZ 9931
Proximity Label-MS Homo sapiens
112 COPS6 10980
Affinity Capture-MS Homo sapiens
113 PRC1 9055
Affinity Capture-MS Homo sapiens
114 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 TOM1 10043
Co-fractionation Homo sapiens
116 SUN2 25777
Two-hybrid Homo sapiens
117 VCAM1 7412
Affinity Capture-MS Homo sapiens
118 DDX6 1656
Affinity Capture-MS Homo sapiens
119 Eif3a 13669
Affinity Capture-MS Mus musculus
120 CUL1 8454
Affinity Capture-MS Homo sapiens
121 RBM42  
Affinity Capture-MS Homo sapiens
122 RRP7A 27341
Co-fractionation Homo sapiens
123 LARP4B 23185
Proximity Label-MS Homo sapiens
124 ATXN2 6311
Proximity Label-MS Homo sapiens
125 VRK3 51231
Affinity Capture-MS Homo sapiens
126 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
127 DDX21 9188
Affinity Capture-MS Homo sapiens
128 RPL4 6124
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
129 DRG1 4733
Affinity Capture-MS Homo sapiens
130 EIF2A 83939
Proximity Label-MS Homo sapiens
131 UBAP2L 9898
Proximity Label-MS Homo sapiens
132 ZMYM1 79830
Cross-Linking-MS (XL-MS) Homo sapiens
133 VRK1 7443
Affinity Capture-MS Homo sapiens
134 GPBP1L1  
Proximity Label-MS Homo sapiens
135 Rrbp1  
Affinity Capture-MS Mus musculus
136 RPLP0 6175
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
137 RPLP0P6 220717
Co-fractionation Homo sapiens
138 Ksr1  
Affinity Capture-MS Mus musculus
139 RAD21 5885
Affinity Capture-Western Homo sapiens
140 LOC101929876 101929876
Co-fractionation Homo sapiens
141 RPL32 6161
Co-fractionation Homo sapiens
142 RPS2 6187
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
143 RC3H2  
Affinity Capture-MS Homo sapiens
144 UBAP2 55833
Proximity Label-MS Homo sapiens
145 EGFR 1956
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
146 FUS 2521
Affinity Capture-MS Homo sapiens
147 TNRC6B  
Proximity Label-MS Homo sapiens
148 RPS27 6232
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
149 CDK2 1017
Affinity Capture-MS Homo sapiens
150 MYC  
Affinity Capture-MS Homo sapiens
151 CEBPZ  
Proximity Label-MS Homo sapiens
152 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
153 DDRGK1 65992
Affinity Capture-MS Homo sapiens
154 LARP4 113251
Proximity Label-MS Homo sapiens
155 EIF3H 8667
Co-fractionation Homo sapiens
156 SLC16A1 6566
Cross-Linking-MS (XL-MS) Homo sapiens
157 RPL13 6137
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
158 GIGYF2 26058
Proximity Label-MS Homo sapiens
159 PRRC2A 7916
Proximity Label-MS Homo sapiens
160 GPBP1  
Proximity Label-MS Homo sapiens
161 ILF3 3609
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
162 ATXN3 4287
Affinity Capture-MS Homo sapiens
163 PGRMC1 10857
Co-fractionation Homo sapiens
164 FXR1 8087
Proximity Label-MS Homo sapiens
165 GKAP1  
Proximity Label-MS Homo sapiens
166 RPS12 6206
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
167 CAPZA2 830
Co-fractionation Homo sapiens
168 RPL23 9349
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
169 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
170 RPS5 6193
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
171 YTHDF3  
Proximity Label-MS Homo sapiens
172 RPS26 6231
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
173 CDV3 55573
Proximity Label-MS Homo sapiens
174 DHX38 9785
Co-fractionation Homo sapiens
175 YBX3 8531
Proximity Label-MS Homo sapiens
176 RPL7A 6130
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
177 PUM1 9698
Proximity Label-MS Homo sapiens
178 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
179 PSMD1 5707
Proximity Label-MS Homo sapiens
180 CUL4A 8451
Affinity Capture-MS Homo sapiens
181 RALY 22913
Co-fractionation Homo sapiens
182 NUPL2 11097
Proximity Label-MS Homo sapiens
183 ABCF3 55324
Proximity Label-MS Homo sapiens
184 UBE2H 7328
Affinity Capture-MS Homo sapiens
185 RIOK1 83732
Proximity Label-MS Homo sapiens
186 ZC3H7A  
Proximity Label-MS Homo sapiens
187 LARP1B 55132
Proximity Label-MS Homo sapiens
188 RPS19 6223
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
189 BYSL 705
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
190 SSB 6741
Affinity Capture-MS Homo sapiens
191 FUBP3 8939
Proximity Label-MS Homo sapiens
192 PSMD10 5716
Co-fractionation Homo sapiens
193 PTPN1 5770
Co-fractionation Homo sapiens
194 FAU 2197
Co-fractionation Homo sapiens
195 ATG13 9776
Affinity Capture-MS Homo sapiens
196 DIMT1 27292
Affinity Capture-MS Homo sapiens
197 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 RPL10A 4736
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
199 TNRC6A 27327
Proximity Label-MS Homo sapiens
200 DYNC1LI2 1783
Co-fractionation Homo sapiens
201 MCM2 4171
Affinity Capture-MS Homo sapiens
202 EIF3B 8662
Affinity Capture-MS Homo sapiens
203 C2orf44  
Cross-Linking-MS (XL-MS) Homo sapiens
204 ITGA4 3676
Affinity Capture-MS Homo sapiens
205 RPL29 6159
Co-fractionation Homo sapiens
206 YAF2  
Affinity Capture-MS Homo sapiens
207 PABPC4 8761
Proximity Label-MS Homo sapiens
208 RBM8A 9939
Affinity Capture-MS Homo sapiens
209 FOXP1 27086
Protein-RNA Homo sapiens
210 LIN28A  
Affinity Capture-MS Homo sapiens
211 Bcas2  
Affinity Capture-MS Mus musculus
212 RPL27 6155
Co-fractionation Homo sapiens
213 CNOT2  
Proximity Label-MS Homo sapiens
214 RPL9 6133
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
215 LSM14B 149986
Proximity Label-MS Homo sapiens
216 CUL4B 8450
Affinity Capture-MS Homo sapiens
217 PLEKHO1 51177
Two-hybrid Homo sapiens
218 RPS10 6204
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
219 PNO1 56902
Co-fractionation Homo sapiens
220 RPL5 6125
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
221 MKRN2 23609
Proximity Label-MS Homo sapiens
222 CNOT1 23019
Proximity Label-MS Homo sapiens
223 RPA2 6118
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
224 BARD1 580
Two-hybrid Homo sapiens
225 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
226 RPL36 25873
Co-fractionation Homo sapiens
227 RPA4  
Proximity Label-MS Homo sapiens
228 RPLP1 6176
Co-fractionation Homo sapiens
229 ENY2 56943
Affinity Capture-MS Homo sapiens
230 HMGB2 3148
Affinity Capture-MS Homo sapiens
231 RPL11 6135
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
232 LARP1 23367
Proximity Label-MS Homo sapiens
233 HABP4  
Proximity Label-MS Homo sapiens
234 ZAK 51776
Proximity Label-MS Homo sapiens
235 SPATS2L 26010
Proximity Label-MS Homo sapiens
236 TDRD3  
Proximity Label-MS Homo sapiens
237 ECT2 1894
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
238 HSP90AB1 3326
Cross-Linking-MS (XL-MS) Homo sapiens
239 RPL21 6144
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
240 FBXO6 26270
Affinity Capture-MS Homo sapiens
241 MDM4  
Affinity Capture-Western Homo sapiens
242 POLR2A 5430
Co-fractionation Homo sapiens
243 SEMA4A  
Proximity Label-MS Homo sapiens
244 NCAPH 23397
Affinity Capture-MS Homo sapiens
245 RABAC1 10567
Two-hybrid Homo sapiens
246 FXR2 9513
Proximity Label-MS Homo sapiens
247 RPS13 6207
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
248 RPS14 6208
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
249 RPL12 6136
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
250 PIK3CA 5290
Two-hybrid Homo sapiens
251 RPL22 6146
Co-fractionation Homo sapiens
252 HDLBP 3069
Proximity Label-MS Homo sapiens
253 RPL18 6141
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
254 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
255 Eif3e 16341
Affinity Capture-MS Mus musculus
256 TSR1 55720
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
257 REEP6  
Two-hybrid Homo sapiens
258 AHSA1 10598
Affinity Capture-MS Homo sapiens
259 PRMT3 10196
Co-fractionation Homo sapiens
260 RPL3L 6123
Co-fractionation Homo sapiens
261 RPS25 6230
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
262 YTHDF2 51441
Proximity Label-MS Homo sapiens
263 RPL6 6128
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
264 RPS21 6227
Co-fractionation Homo sapiens
265 FOLR1 2348
Affinity Capture-MS Homo sapiens
266 DDX3X 1654
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
267 PRRC2C 23215
Proximity Label-MS Homo sapiens
268 RPA1 6117
Co-fractionation Homo sapiens
269 HNRNPM 4670
Cross-Linking-MS (XL-MS) Homo sapiens
270 G3BP1 10146
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
271 CREBBP  
Two-hybrid Homo sapiens
272 PRRC2B  
Proximity Label-MS Homo sapiens
273 RPL34 6164
Co-fractionation Homo sapiens
274 PDZD8 118987
Affinity Capture-MS Homo sapiens
275 UFL1 23376
Affinity Capture-MS Homo sapiens
276 RPL38 6169
Co-fractionation Homo sapiens
277 RPS7 6201
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
278 RPL8 6132
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
279 RPS27L 51065
Co-fractionation Homo sapiens
280 SERBP1 26135
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
281 LGALS3 3958
Affinity Capture-MS Homo sapiens
282 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 UBA6 55236
Co-fractionation Homo sapiens
284 IGF2BP2 10644
Proximity Label-MS Homo sapiens
285 EIF5 1983
Affinity Capture-MS Homo sapiens
286 UBA52 7311
Co-fractionation Homo sapiens
287 EIF3L 51386
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
288 RPSA 3921
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
289 SRP19 6728
Affinity Capture-MS Homo sapiens
290 TNFAIP3 7128
Two-hybrid Homo sapiens
291 RIT1 6016
Negative Genetic Homo sapiens
292 IGF2BP1 10642
Proximity Label-MS Homo sapiens
293 CUEDC2  
Proximity Label-MS Homo sapiens
294 PAXIP1  
Two-hybrid Homo sapiens
295 RPS3A 6189
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
296 DOCK4 9732
Cross-Linking-MS (XL-MS) Homo sapiens
297 RPS4X 6191
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
298 RPL30 6156
Co-fractionation Homo sapiens
299 YTHDF1 54915
Proximity Label-MS Homo sapiens
300 TNRC18  
Cross-Linking-MS (XL-MS) Homo sapiens
301 RPL13A 23521
Co-fractionation Homo sapiens
302 RPL37A 6168
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
303 RPL10 6134
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
304 RPL15 6138
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
305 MRPL23 6150
Co-fractionation Homo sapiens
306 DHX57 90957
Proximity Label-MS Homo sapiens
307 APP 351
Reconstituted Complex Homo sapiens
308 ILF2 3608
Co-fractionation Homo sapiens
309 GSK3A 2931
Affinity Capture-MS Homo sapiens
310 TOP2A 7153
Affinity Capture-MS Homo sapiens
311 RNF10  
Proximity Label-MS Homo sapiens
312 IMPDH2 3615
Co-fractionation Homo sapiens
313 SP3  
Two-hybrid Homo sapiens
314 ATXN2L 11273
Proximity Label-MS Homo sapiens
315 KIF5B 3799
Co-fractionation Homo sapiens
316 COPS5 10987
Affinity Capture-MS Homo sapiens
317 FBXW7  
Affinity Capture-MS Homo sapiens
318 RPL24 6152
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
319 PSMD9 5715
Affinity Capture-MS Homo sapiens
320 CALM3 808
Affinity Capture-MS Homo sapiens
321 ABCE1 6059
Affinity Capture-MS Homo sapiens
322 ZCCHC3  
Proximity Label-MS Homo sapiens
323 SRP68 6730
Affinity Capture-MS Homo sapiens
324 MYCN  
Affinity Capture-MS Homo sapiens
325 SSR3 6747
Cross-Linking-MS (XL-MS) Homo sapiens
326 CTCF  
Affinity Capture-MS Homo sapiens
327 ESR1  
Affinity Capture-MS Homo sapiens
328 LSM12 124801
Proximity Label-MS Homo sapiens
329 TPT1 7178
Affinity Capture-MS Homo sapiens
330 RPS23 6228
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
331 SRP9 6726
Affinity Capture-MS Homo sapiens
332 PSMD4 5710
Proximity Label-MS Homo sapiens
333 DDX5 1655
Co-fractionation Homo sapiens
334 WIPI1 55062
Proximity Label-MS Homo sapiens
335 RPL27A 6157
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
336 EIF4G2 1982
Proximity Label-MS Homo sapiens
337 UPF1 5976
Proximity Label-MS Homo sapiens
338 ZC3H15 55854
Proximity Label-MS Homo sapiens
339 RPS15A 6210
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
340 COG4 25839
Co-fractionation Homo sapiens
341 USP10 9100
Proximity Label-MS Homo sapiens
342 ST13 6767
Cross-Linking-MS (XL-MS) Homo sapiens
343 ASCC3 10973
Proximity Label-MS Homo sapiens
344 IPO5 3843
Co-fractionation Homo sapiens
345 RPLP2 6181
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
346 FANCD2  
Affinity Capture-MS Homo sapiens
347 CDK9 1025
Affinity Capture-MS Homo sapiens
348 DNAJC2 27000
Affinity Capture-MS Homo sapiens
349 RPL35 11224
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
350 CTNNB1 1499
Affinity Capture-MS Homo sapiens
351 DHX29 54505
Cross-Linking-MS (XL-MS) Homo sapiens
352 RPS8 6202
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
353 RPL3 6122
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
354 RBMS1 5937
Proximity Label-MS Homo sapiens
355 RPL7 6129
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
356 AURKB 9212
Affinity Capture-MS Homo sapiens
357 MRPL1  
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
358 EIF4H 7458
Proximity Label-MS Homo sapiens
359 IL7R  
Protein-RNA Homo sapiens
360 TXNL1 9352
Proximity Label-MS Homo sapiens
361 RPS29 6235
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
362 BMP4 652
Affinity Capture-MS Homo sapiens
363 GNB2L1 10399
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
364 MDM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
365 EIF3D 8664
Co-fractionation Homo sapiens
366 MYLK 4638
Proximity Label-MS Homo sapiens
367 MPP6 51678
Two-hybrid Homo sapiens
368 NUFIP2 57532
Proximity Label-MS Homo sapiens
369 CUL5 8065
Affinity Capture-MS Homo sapiens
370 SMURF1 57154
Affinity Capture-MS Homo sapiens
371 SRP72 6731
Affinity Capture-MS Homo sapiens
372 CHD4 1108
Cross-Linking-MS (XL-MS) Homo sapiens
373 CNOT3 4849
Proximity Label-MS Homo sapiens
374 RPS28 6234
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
375 OTUD4  
Proximity Label-MS Homo sapiens
376 NRAS 4893
Two-hybrid Homo sapiens
377 SEC62 7095
Cross-Linking-MS (XL-MS) Homo sapiens
378 TRIP4 9325
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
379 IBTK 25998
Proximity Label-MS Homo sapiens
380 TRIM31  
Affinity Capture-MS Homo sapiens
381 CBX8 57332
Affinity Capture-MS Homo sapiens
382 RPS6 6194
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
383 EEFSEC 60678
Co-fractionation Homo sapiens
384 C9orf72  
Affinity Capture-MS Homo sapiens
385 PSPC1 55269
Affinity Capture-MS Homo sapiens
386 EXOSC1 51013
Affinity Capture-MS Homo sapiens
387 NEDD8 4738
Affinity Capture-MS Homo sapiens
388 ALDOA 226
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which RPS20 is involved
PathwayEvidenceSource
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S TAS Reactome
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
Formation of the ternary complex, and subsequently, the 43S complex TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
Ribosomal scanning and start codon recognition TAS Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV-1 Infection TAS Reactome
SARS-CoV-1 modulates host translation machinery TAS Reactome
SARS-CoV-1-host interactions TAS Reactome
SARS-CoV-2 Infection TAS Reactome
SARS-CoV-2 modulates host translation machinery TAS Reactome
SARS-CoV-2-host interactions TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Translation initiation complex formation TAS Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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