Gene description for UBB
Gene name ubiquitin B
Gene symbol UBB
Other names/aliases -
Species Homo sapiens
 Database cross references - UBB
ExoCarta ExoCarta_7314
Vesiclepedia VP_7314
Entrez Gene 7314
HGNC 12463
MIM 191339
UniProt P0CG47  
 UBB identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Breast milk 17641064    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Saliva 19199708    
Tracheobronchial cells 19190083    
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for UBB
Molecular Function
    protein binding GO:0005515 IPI
    protein tag activity GO:0031386 IBA
    ubiquitin protein ligase binding GO:0031625 IBA
Biological Process
    male meiosis I GO:0007141 IEA
    female meiosis I GO:0007144 IEA
    female gonad development GO:0008585 IEA
    protein ubiquitination GO:0016567 IBA
    modification-dependent protein catabolic process GO:0019941 IBA
    hypothalamus gonadotrophin-releasing hormone neuron development GO:0021888 IEA
    positive regulation of protein ubiquitination GO:0031398 IDA
    regulation of neuron apoptotic process GO:0043523 IDA
    mitochondrion transport along microtubule GO:0047497 IDA
    neuron projection morphogenesis GO:0048812 IMP
    regulation of mitochondrial membrane potential GO:0051881 IDA
    fat pad development GO:0060613 IEA
    regulation of proteasomal protein catabolic process GO:0061136 IDA
    seminiferous tubule development GO:0072520 IEA
    energy homeostasis GO:0097009 IEA
    positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902255 IDA
    positive regulation of protein monoubiquitination GO:1902527 IMP
Subcellular Localization
    extracellular space GO:0005615 HDA
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial outer membrane GO:0005741 TAS
    endoplasmic reticulum membrane GO:0005789 TAS
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 TAS
    endosome membrane GO:0010008 TAS
    endocytic vesicle membrane GO:0030666 TAS
    vesicle GO:0031982 HDA
    neuron projection GO:0043005 IDA
    neuronal cell body GO:0043025 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified UBB in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 46
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|MHCII|CD81|CD86
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors "Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Colostrum
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
3
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
4
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
5
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
10
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
13
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
20
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
21
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
22
Experiment ID 34
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
TSG101|CD63|MHCI|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19190083    
Organism Homo sapiens
Experiment description Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Authors "Kesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK"
Journal name FASEB
Publication year 2009
Sample Tracheobronchial cells
Sample name Tracheobronchial epithelial cells
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.16 -1.18 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
FACS
23
Experiment ID 193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 194
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 195
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UBB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HIST1H2BJ 8970
Cross-Linking-MS (XL-MS) Homo sapiens
2 CITED1 4435
Affinity Capture-MS Homo sapiens
3 FAM58A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 CIB4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 LIG4 3981
Two-hybrid Homo sapiens
6 AFG3L2 10939
Affinity Capture-MS Homo sapiens
7 CENPH  
Affinity Capture-MS Homo sapiens
8 BTBD6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 TRAPPC2 6399
Affinity Capture-MS Homo sapiens
10 SPRTN  
Affinity Capture-MS Homo sapiens
11 UBE2A  
Affinity Capture-MS Homo sapiens
12 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
13 REEP5 7905
Proximity Label-MS Homo sapiens
14 MAGEA3  
Affinity Capture-MS Homo sapiens
15 NME3 4832
Affinity Capture-MS Homo sapiens
16 ZFAND2B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SLC45A2 51151
Affinity Capture-MS Homo sapiens
18 USP48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 PSMA4 5685
Affinity Capture-MS Homo sapiens
20 HIST1H2BN 8341
Cross-Linking-MS (XL-MS) Homo sapiens
21 TPTE2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 USP5 8078
Cross-Linking-MS (XL-MS) Homo sapiens
23 EIF2B2 8892
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 ADRB2  
Affinity Capture-MS Homo sapiens
25 DNAJB2 3300
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 PLSCR4  
Two-hybrid Homo sapiens
27 HYPM  
Affinity Capture-MS Homo sapiens
28 GMCL1P1  
Affinity Capture-MS Homo sapiens
29 PRKACG  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 FBXL21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 APBA3  
Affinity Capture-MS Homo sapiens
32 HIST1H2BB 3018
Cross-Linking-MS (XL-MS) Homo sapiens
33 CNP 1267
Affinity Capture-MS Homo sapiens
34 HIST3H2BB 128312
Cross-Linking-MS (XL-MS) Homo sapiens
35 IL36RN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 BASP1 10409
Affinity Capture-MS Homo sapiens
37 DHX57 90957
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 SLC17A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 VWA5A 4013
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 NR2C2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 FAXC  
Affinity Capture-MS Homo sapiens
42 APP 351
PCA Homo sapiens
43 KXD1 79036
Affinity Capture-MS Homo sapiens
44 RPS3 6188
Cross-Linking-MS (XL-MS) Homo sapiens
45 TGM2 7052
Affinity Capture-MS Homo sapiens
46 ZNF215  
Affinity Capture-MS Homo sapiens
47 LMO2  
Affinity Capture-MS Homo sapiens
48 PPTC7 160760
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 LOC102724334 102724334
Cross-Linking-MS (XL-MS) Homo sapiens
50 RHEB 6009
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 RNF31 55072
Affinity Capture-MS Homo sapiens
52 GAGE1  
Affinity Capture-MS Homo sapiens
53 SCN1B  
Affinity Capture-MS Homo sapiens
54 SYCE3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 CTLA4  
Affinity Capture-MS Homo sapiens
56 HIST1H2BM 8342
Cross-Linking-MS (XL-MS) Homo sapiens
57 IGF1R 3480
Affinity Capture-MS Homo sapiens
58 MCM2 4171
Affinity Capture-MS Homo sapiens
59 UBE2K 3093
Cross-Linking-MS (XL-MS) Homo sapiens
60 SLC13A2 9058
Affinity Capture-MS Homo sapiens
61 WDR83  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 FAM8A1 51439
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 SUMO2 6613
Affinity Capture-MS Homo sapiens
64 RAB3B 5865
Proximity Label-MS Homo sapiens
65 UBQLN1 29979
Two-hybrid Homo sapiens
66 IMPDH2 3615
Proximity Label-MS Homo sapiens
67 UBE2L3 7332
Affinity Capture-MS Homo sapiens
68 PQLC2L  
Affinity Capture-MS Homo sapiens
69 HDAC6 10013
Affinity Capture-MS Homo sapiens
70 PFDN4 5203
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 GCG  
Affinity Capture-MS Homo sapiens
72 ZFYVE1 53349
Affinity Capture-MS Homo sapiens
73 NPM1 4869
Proximity Label-MS Homo sapiens
74 CALCOCO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
75 ASB9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
76 TNFAIP3 7128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 PRPS1 5631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 PRDX2 7001
Affinity Capture-MS Homo sapiens
79 MAGED2 10916
Affinity Capture-MS Homo sapiens
80 NUB1 51667
Affinity Capture-MS Homo sapiens
81 HIST1H2BA 255626
Cross-Linking-MS (XL-MS) Homo sapiens
82 HBG2 3048
Affinity Capture-MS Homo sapiens
83 CLRN2  
Affinity Capture-MS Homo sapiens
84 POLI  
Two-hybrid Homo sapiens
85 ITGA4 3676
Affinity Capture-MS Homo sapiens
86 HSPA1A 3303
Cross-Linking-MS (XL-MS) Homo sapiens
87 TDRD5  
Affinity Capture-MS Homo sapiens
88 VCAM1 7412
Affinity Capture-MS Homo sapiens
89 CEP57  
Affinity Capture-MS Homo sapiens
90 ATP6V0D1 9114
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 METTL23  
Affinity Capture-MS Homo sapiens
92 RNF126  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 GNG8  
Affinity Capture-MS Homo sapiens
94 CYP7B1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 SDCBP 6386
Two-hybrid Homo sapiens
96 USP7 7874
Co-crystal Structure Homo sapiens
97 FAF2 23197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 ZNRF1  
Affinity Capture-MS Homo sapiens
99 HAO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 UBAC1 10422
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
101 NEDD4 4734
Affinity Capture-MS Homo sapiens
102 TAX1BP1 8887
Two-hybrid Homo sapiens
103 RNF11 26994
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 HMGA1 3159
Affinity Capture-MS Homo sapiens
105 PRPH2 5961
Affinity Capture-MS Homo sapiens
106 KCNE3  
Affinity Capture-MS Homo sapiens
107 RNF181  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
108 LTBR 4055
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 CAV3 859
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 PFN1 5216
Affinity Capture-MS Homo sapiens
111 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
112 AURKA 6790
Affinity Capture-MS Homo sapiens
113 UBE2E3 10477
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 SPDYE7P  
Affinity Capture-MS Homo sapiens
115 HAUS2  
Affinity Capture-MS Homo sapiens
116 RAD23B 5887
Two-hybrid Homo sapiens
117 GYG2  
Affinity Capture-MS Homo sapiens
118 MTCH2 23788
Proximity Label-MS Homo sapiens
119 ATG4A  
Affinity Capture-MS Homo sapiens
120 ENSA 2029
Affinity Capture-MS Homo sapiens
121 KCNG1 3755
Affinity Capture-MS Homo sapiens
122 MED20 9477
Affinity Capture-MS Homo sapiens
123 NRSN1  
Affinity Capture-MS Homo sapiens
124 UXT 8409
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 CRY1  
Affinity Capture-MS Homo sapiens
126 PSMC4 5704
Affinity Capture-MS Homo sapiens
127 CDKN1A  
Affinity Capture-MS Homo sapiens
128 PCBD1 5092
Affinity Capture-MS Homo sapiens
129 UBE2D4  
Affinity Capture-MS Homo sapiens
130 PDGFRB 5159
Affinity Capture-MS Homo sapiens
131 SNAP91 9892
Affinity Capture-MS Homo sapiens
132 HRSP12 10247
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 OR4N2  
Affinity Capture-MS Homo sapiens
134 TUBGCP4 27229
Affinity Capture-MS Homo sapiens
135 PSMD14 10213
Affinity Capture-MS Homo sapiens
136 WSB2 55884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 DAZAP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
138 PLEKHB2 55041
Two-hybrid Homo sapiens
139 UBAC2 337867
Affinity Capture-MS Homo sapiens
140 RAB30 27314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 LGALS13  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 RPS27A 6233
Cross-Linking-MS (XL-MS) Homo sapiens
143 MKRN2 23609
Affinity Capture-RNA Homo sapiens
144 APOL2 23780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 C16orf58 64755
Affinity Capture-MS Homo sapiens
146 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 C4orf22  
Affinity Capture-MS Homo sapiens
148 METTL21C  
Affinity Capture-MS Homo sapiens
149 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
150 PPARD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 WIPI1 55062
Affinity Capture-MS Homo sapiens
152 IL20RA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
153 GRTP1 79774
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 ARL16  
Affinity Capture-MS Homo sapiens
155 UBC 7316
Cross-Linking-MS (XL-MS) Homo sapiens
156 PRMT2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 DHFRL1  
Proximity Label-MS Homo sapiens
158 LAGE3  
Affinity Capture-MS Homo sapiens
159 VCPKMT  
Affinity Capture-MS Homo sapiens
160 TEX19  
Affinity Capture-MS Homo sapiens
161 NICN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 ARL2BP 23568
Affinity Capture-MS Homo sapiens
163 MAGOH 4116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
165 CEP76  
Affinity Capture-MS Homo sapiens
166 COPS7B 64708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 BRAP  
Two-hybrid Homo sapiens
168 RASL10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 INF2 64423
Affinity Capture-MS Homo sapiens
170 H3F3C 440093
Cross-Linking-MS (XL-MS) Homo sapiens
171 TNFRSF10A 8797
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 FAM73B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 ANKRD9  
Affinity Capture-MS Homo sapiens
174 HIST2H2BE 8349
Cross-Linking-MS (XL-MS) Homo sapiens
175 MGMT 4255
Affinity Capture-MS Homo sapiens
176 KDF1  
Affinity Capture-MS Homo sapiens
177 FAM86B2  
Affinity Capture-MS Homo sapiens
178 RAD51D  
Affinity Capture-MS Homo sapiens
179 VWA2 340706
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 CSNK1G3 1456
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 KCNS3 3790
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 UBE2S  
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
183 PCTP  
Affinity Capture-MS Homo sapiens
184 RNF40 9810
Affinity Capture-MS Homo sapiens
185 PAEP  
Affinity Capture-MS Homo sapiens
186 QPCT 25797
Affinity Capture-MS Homo sapiens
187 RAPGEF5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
188 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
189 RPN2 6185
Proximity Label-MS Homo sapiens
190 PANK2 80025
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 CDC73  
Affinity Capture-MS Homo sapiens
192 RNF166  
Affinity Capture-MS Homo sapiens
193 VPS36 51028
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 CAPN15  
Affinity Capture-MS Homo sapiens
195 CPA6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 NME1-NME2 654364
Affinity Capture-MS Homo sapiens
197 ECT2 1894
Two-hybrid Homo sapiens
198 RPN1 6184
Proximity Label-MS Homo sapiens
199 COMMD8 54951
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 HIST2H2BF 440689
Cross-Linking-MS (XL-MS) Homo sapiens
201 YAF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 IQCB1  
Affinity Capture-MS Homo sapiens
203 SRSF1 6426
Affinity Capture-MS Homo sapiens
204 COPS8 10920
Affinity Capture-MS Homo sapiens
205 TNFRSF1A 7132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 PSMA2 5683
Affinity Capture-MS Homo sapiens
207 SKP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 RAD18  
Affinity Capture-MS Homo sapiens
209 CBLN4  
Affinity Capture-MS Homo sapiens
210 TMCO6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 AKAP13 11214
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
212 TRIM11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 BCAP31 10134
Proximity Label-MS Homo sapiens
214 FBXO6 26270
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
215 METTL21B  
Affinity Capture-MS Homo sapiens
216 EFCAB11  
Affinity Capture-MS Homo sapiens
217 ABCB1 5243
Affinity Capture-Western Homo sapiens
218 TMEM136  
Affinity Capture-MS Homo sapiens
219 SUZ12  
Affinity Capture-MS Homo sapiens
220 HIST3H3 8290
Cross-Linking-MS (XL-MS) Homo sapiens
221 FN1 2335
Affinity Capture-MS Homo sapiens
222 HIST1H2BO 8348
Cross-Linking-MS (XL-MS) Homo sapiens
223 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
224 AURKB 9212
Affinity Capture-MS Homo sapiens
225 NLGN4Y 22829
Affinity Capture-MS Homo sapiens
226 ARIH2 10425
Affinity Capture-MS Homo sapiens
227 CEP250 11190
Affinity Capture-MS Homo sapiens
228 CUL9  
Affinity Capture-MS Homo sapiens
229 MED10  
Affinity Capture-MS Homo sapiens
230 MYO1D 4642
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
231 TADA2A  
Affinity Capture-MS Homo sapiens
232 PCDHA4 56144
Affinity Capture-MS Homo sapiens
233 CRYBA4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
234 H2AFB1  
Affinity Capture-MS Homo sapiens
235 FBXO2 26232
Affinity Capture-MS Homo sapiens
236 EPN3 55040
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
237 POLR2F  
Affinity Capture-MS Homo sapiens
238 GPR21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
239 PPAPDC1A  
Affinity Capture-MS Homo sapiens
240 AKT2 208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
241 TSPAN16  
Affinity Capture-MS Homo sapiens
242 BCL2L1 598
Affinity Capture-MS Homo sapiens
243 UBL7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
244 FNTB 2342
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
245 MFN2 9927
Proximity Label-MS Homo sapiens
246 HAX1  
Proximity Label-MS Homo sapiens
247 B9D2 80776
Affinity Capture-MS Homo sapiens
248 FAM188A 80013
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 RNF185  
Affinity Capture-MS Homo sapiens
250 SLC51A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 CDH19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 HUWE1 10075
Affinity Capture-MS Homo sapiens
253 TMEM31  
Affinity Capture-MS Homo sapiens
254 CHDC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
255 DENND6A 201627
Proximity Label-MS Homo sapiens
256 TRIM5 85363
Two-hybrid Homo sapiens
257 CRYAA 1409
Affinity Capture-MS Homo sapiens
258 FBXL15  
Affinity Capture-MS Homo sapiens
259 UBQLN2 29978
Two-hybrid Homo sapiens
260 MYCBP 26292
Affinity Capture-MS Homo sapiens
261 UBE3A 7337
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
262 ARRB2 409
Affinity Capture-MS Homo sapiens
263 C7orf69  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 GLT1D1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
265 FAM153B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
266 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
267 CDC20 991
Affinity Capture-MS Homo sapiens
268 FADS3 3995
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
269 SWSAP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 USP25  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
271 CUTA 51596
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
272 USP46 64854
Co-crystal Structure Homo sapiens
273 TP53 7157
Affinity Capture-MS Homo sapiens
274 FUZ 80199
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
275 TUBG1 7283
Affinity Capture-MS Homo sapiens
276 AP2S1 1175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
277 NUCKS1 64710
Affinity Capture-MS Homo sapiens
278 MCM5 4174
Affinity Capture-MS Homo sapiens
279 RSPH14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
280 FBXL16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
281 CHURC1  
Affinity Capture-MS Homo sapiens
282 FANCG 2189
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
283 RNF19B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 IKBKG 8517
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
285 LITAF 9516
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 SSR1 6745
Proximity Label-MS Homo sapiens
287 SQSTM1 8878
Proximity Label-MS Homo sapiens
288 ARPC5 10092
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 OR1D4  
Affinity Capture-MS Homo sapiens
290 UBE3B 89910
Affinity Capture-MS Homo sapiens
291 ZMYND12  
Affinity Capture-MS Homo sapiens
292 DFFB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
293 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
294 APBB3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 TRAPPC13 80006
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
296 OR2G6  
Affinity Capture-MS Homo sapiens
297 BUB3 9184
Affinity Capture-MS Homo sapiens
298 UBE2D2 7322
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
299 KIAA1715 80856
Proximity Label-MS Homo sapiens
300 BRK1 55845
Affinity Capture-MS Homo sapiens
301 TNNC1  
Affinity Capture-MS Homo sapiens
302 UBB 7314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
303 USP30  
Co-crystal Structure Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
304 KDM1A 23028
Proximity Label-MS Homo sapiens
305 CLMN  
Affinity Capture-MS Homo sapiens
306 EZH2  
Affinity Capture-MS Homo sapiens
307 DAAM2 23500
Affinity Capture-MS Homo sapiens
308 H3F3A 3020
Cross-Linking-MS (XL-MS) Homo sapiens
309 H2AFZ 3015
Affinity Capture-MS Homo sapiens
310 ARRB1 408
Affinity Capture-MS Homo sapiens
311 AIRE  
Affinity Capture-MS Homo sapiens
312 SPANXA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 MTURN  
Two-hybrid Homo sapiens
314 AANAT  
Affinity Capture-MS Homo sapiens
315 INPP5K 51763
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
316 KDM5C  
Affinity Capture-MS Homo sapiens
317 TNNC2  
Affinity Capture-MS Homo sapiens
318 WDR90  
Affinity Capture-MS Homo sapiens
319 SLC14A1  
Affinity Capture-MS Homo sapiens
320 SPINK7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
321 EID1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
322 NR1I3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
323 AR 367
Affinity Capture-MS Homo sapiens
324 PRSS3 5646
Affinity Capture-MS Homo sapiens
325 HLA-DRB3 3125
Affinity Capture-MS Homo sapiens
326 CKAP4 10970
Proximity Label-MS Homo sapiens
327 PLEKHN1  
Affinity Capture-MS Homo sapiens
328 TGM5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
329 LIMK2 3985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
330 CLEC4E  
Affinity Capture-MS Homo sapiens
331 DPP8 54878
Affinity Capture-MS Homo sapiens
332 HSD17B3  
Affinity Capture-MS Homo sapiens
333 C17orf59 54785
Proximity Label-MS Homo sapiens
334 CNPPD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
335 UBA52 7311
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
336 TRAF1 7185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
337 INTU  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which UBB is involved
PathwayEvidenceSource
ABC transporter disorders TAS Reactome
ABC-family proteins mediated transport TAS Reactome
Activated NOTCH1 Transmits Signal to the Nucleus IEA Reactome
Activated NOTCH1 Transmits Signal to the Nucleus TAS Reactome
activated TAK1 mediates p38 MAPK activation TAS Reactome
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins TAS Reactome
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) TAS Reactome
Activation of NF-kappaB in B cells TAS Reactome
Adaptive Immune System TAS Reactome
Adaptive Immune System IEA Reactome
Aerobic respiration and respiratory electron transport TAS Reactome
Aggrephagy IEA Reactome
Aggrephagy TAS Reactome
Alpha-protein kinase 1 signaling pathway TAS Reactome
Amyloid fiber formation TAS Reactome
Antigen processing-Cross presentation IEA Reactome
Antigen processing: Ubiquitination & Proteasome degradation TAS Reactome
Antiviral mechanism by IFN-stimulated genes TAS Reactome
APC-Cdc20 mediated degradation of Nek2A TAS Reactome
APC/C-mediated degradation of cell cycle proteins TAS Reactome
APC/C:Cdc20 mediated degradation of Cyclin B TAS Reactome
APC/C:Cdc20 mediated degradation of mitotic proteins TAS Reactome
APC/C:Cdc20 mediated degradation of Securin TAS Reactome
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 TAS Reactome
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint TAS Reactome
Apoptosis IEA Reactome
Asparagine N-linked glycosylation TAS Reactome
Assembly Of The HIV Virion TAS Reactome
Assembly of the pre-replicative complex TAS Reactome
Asymmetric localization of PCP proteins TAS Reactome
AUF1 (hnRNP D0) binds and destabilizes mRNA TAS Reactome
Autodegradation of Cdh1 by Cdh1:APC/C TAS Reactome
Autodegradation of the E3 ubiquitin ligase COP1 TAS Reactome
Autophagy IEA Reactome
Autophagy TAS Reactome
Axon guidance TAS Reactome
Axon guidance IEA Reactome
Bacterial Infection Pathways TAS Reactome
Bacterial Infection Pathways IEA Reactome
Beta-catenin independent WNT signaling TAS Reactome
Budding and maturation of HIV virion TAS Reactome
C-type lectin receptors (CLRs) TAS Reactome
Calnexin/calreticulin cycle TAS Reactome
Cargo recognition for clathrin-mediated endocytosis TAS Reactome
Cdc20:Phospho-APC/C mediated degradation of Cyclin A TAS Reactome
CDK-mediated phosphorylation and removal of Cdc6 TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle Checkpoints TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cell death signalling via NRAGE, NRIF and NADE TAS Reactome
Cellular response to chemical stress TAS Reactome
Cellular response to hypoxia TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Cellular Senescence TAS Reactome
Chaperone Mediated Autophagy IEA Reactome
Circadian Clock IEA Reactome
Class I MHC mediated antigen processing & presentation TAS Reactome
Class I MHC mediated antigen processing & presentation IEA Reactome
Clathrin-mediated endocytosis TAS Reactome
CLEC7A (Dectin-1) signaling TAS Reactome
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants TAS Reactome
Constitutive Signaling by NOTCH1 HD Domain Mutants TAS Reactome
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants TAS Reactome
Constitutive Signaling by NOTCH1 PEST Domain Mutants TAS Reactome
Cyclin A:Cdk2-associated events at S phase entry TAS Reactome
Cyclin D associated events in G1 TAS Reactome
Cyclin E associated events during G1/S transition TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Cytokine Signaling in Immune system IEA Reactome
Cytosolic sensors of pathogen-associated DNA TAS Reactome
DDX58/IFIH1-mediated induction of interferon-alpha/beta TAS Reactome
Deactivation of the beta-catenin transactivating complex TAS Reactome
Death Receptor Signaling TAS Reactome
Dectin-1 mediated noncanonical NF-kB signaling TAS Reactome
Defective CFTR causes cystic fibrosis TAS Reactome
Degradation of AXIN TAS Reactome
Degradation of beta-catenin by the destruction complex TAS Reactome
Degradation of DVL TAS Reactome
Degradation of GLI1 by the proteasome TAS Reactome
Degradation of GLI2 by the proteasome IEA Reactome
Deubiquitination TAS Reactome
Deubiquitination IEA Reactome
Developmental Biology TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Disease IEA Reactome
Diseases of carbohydrate metabolism TAS Reactome
Diseases of metabolism TAS Reactome
Diseases of signal transduction by growth factor receptors and second messengers TAS Reactome
Disorders of transmembrane transporters TAS Reactome
DNA Damage Bypass TAS Reactome
DNA Damage Recognition in GG-NER TAS Reactome
DNA Double Strand Break Response TAS Reactome
DNA Double-Strand Break Repair TAS Reactome
DNA Repair TAS Reactome
DNA Replication TAS Reactome
DNA Replication Pre-Initiation TAS Reactome
Downregulation of ERBB2 signaling TAS Reactome
Downregulation of ERBB2:ERBB3 signaling TAS Reactome
Downregulation of ERBB4 signaling TAS Reactome
Downregulation of SMAD2/3:SMAD4 transcriptional activity TAS Reactome
Downregulation of SMAD2/3:SMAD4 transcriptional activity IEA Reactome
Downregulation of TGF-beta receptor signaling IEA Reactome
Downregulation of TGF-beta receptor signaling TAS Reactome
Downstream signaling events of B Cell Receptor (BCR) TAS Reactome
Downstream TCR signaling TAS Reactome
Dual Incision in GG-NER TAS Reactome
Dual incision in TC-NER TAS Reactome
E3 ubiquitin ligases ubiquitinate target proteins TAS Reactome
EGFR downregulation TAS Reactome
Endosomal Sorting Complex Required For Transport (ESCRT) TAS Reactome
ER Quality Control Compartment (ERQC) TAS Reactome
ER-Phagosome pathway IEA Reactome
Evasion by RSV of host interferon responses TAS Reactome
Fanconi Anemia Pathway TAS Reactome
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis TAS Reactome
Fc epsilon receptor (FCERI) signaling TAS Reactome
FCERI mediated NF-kB activation TAS Reactome
FLT3 Signaling TAS Reactome
FLT3 signaling by CBL mutants TAS Reactome
FLT3 signaling in disease TAS Reactome
Formation of Incision Complex in GG-NER TAS Reactome
Formation of TC-NER Pre-Incision Complex TAS Reactome
G1 Phase TAS Reactome
G1/S DNA Damage Checkpoints TAS Reactome
G1/S Transition TAS Reactome
G2/M Checkpoints TAS Reactome
G2/M Transition TAS Reactome
Gap-filling DNA repair synthesis and ligation in GG-NER TAS Reactome
Gap-filling DNA repair synthesis and ligation in TC-NER TAS Reactome
Gene expression (Transcription) TAS Reactome
Gene expression (Transcription) IEA Reactome
Generic Transcription Pathway TAS Reactome
Generic Transcription Pathway IEA Reactome
GLI3 is processed to GLI3R by the proteasome TAS Reactome
Global Genome Nucleotide Excision Repair (GG-NER) TAS Reactome
Glycogen metabolism TAS Reactome
Glycogen storage diseases TAS Reactome
Glycogen synthesis TAS Reactome
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 TAS Reactome
HDR through Homologous Recombination (HRR) TAS Reactome
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) TAS Reactome
Hedgehog 'off' state TAS Reactome
Hedgehog 'off' state IEA Reactome
Hedgehog 'on' state TAS Reactome
Hedgehog 'on' state IEA Reactome
Hedgehog ligand biogenesis TAS Reactome
Hh mutants abrogate ligand secretion TAS Reactome
Hh mutants are degraded by ERAD TAS Reactome
HIV Infection TAS Reactome
HIV Life Cycle TAS Reactome
Homology Directed Repair TAS Reactome
Host Interactions of HIV factors TAS Reactome
IKK complex recruitment mediated by RIP1 TAS Reactome
Immune System TAS Reactome
Immune System IEA Reactome
Inactivation of CSF3 (G-CSF) signaling TAS Reactome
Infection with Mycobacterium tuberculosis TAS Reactome
Infectious disease TAS Reactome
Infectious disease IEA Reactome
InlA-mediated entry of Listeria monocytogenes into host cells TAS Reactome
InlB-mediated entry of Listeria monocytogenes into host cell TAS Reactome
InlB-mediated entry of Listeria monocytogenes into host cell IEA Reactome
Innate Immune System TAS Reactome
Interferon alpha/beta signaling TAS Reactome
Interferon Signaling TAS Reactome
Interleukin-1 family signaling TAS Reactome
Interleukin-1 signaling TAS Reactome
Interleukin-17 signaling TAS Reactome
Interleukin-3, Interleukin-5 and GM-CSF signaling TAS Reactome
Intracellular signaling by second messengers TAS Reactome
Ion channel transport TAS Reactome
IRAK1 recruits IKK complex TAS Reactome
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation TAS Reactome
IRAK2 mediated activation of TAK1 complex TAS Reactome
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation TAS Reactome
Iron uptake and transport TAS Reactome
ISG15 antiviral mechanism TAS Reactome
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 TAS Reactome
Josephin domain DUBs TAS Reactome
KEAP1-NFE2L2 pathway TAS Reactome
Late endosomal microautophagy IEA Reactome
Late Phase of HIV Life Cycle TAS Reactome
Late SARS-CoV-2 Infection Events IEA Reactome
Listeria monocytogenes entry into host cells TAS Reactome
Listeria monocytogenes entry into host cells IEA Reactome
M Phase TAS Reactome
Macroautophagy TAS Reactome
Macroautophagy IEA Reactome
MAP kinase activation TAS Reactome
MAP3K8 (TPL2)-dependent MAPK1/3 activation TAS Reactome
MAPK family signaling cascades TAS Reactome
MAPK1/MAPK3 signaling TAS Reactome
MAPK6/MAPK4 signaling TAS Reactome
Maturation of protein E TAS Reactome
Maturation of protein E IEA Reactome
Membrane binding and targetting of GAG proteins TAS Reactome
Membrane Trafficking TAS Reactome
Metabolism TAS Reactome
Metabolism of carbohydrates TAS Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Metalloprotease DUBs TAS Reactome
Mitophagy TAS Reactome
Mitotic Anaphase TAS Reactome
Mitotic G1 phase and G1/S transition TAS Reactome
Mitotic G2-G2/M phases TAS Reactome
Mitotic Metaphase and Anaphase TAS Reactome
Modulation by Mtb of host immune system TAS Reactome
MyD88 cascade initiated on plasma membrane TAS Reactome
MyD88 dependent cascade initiated on endosome TAS Reactome
MyD88-independent TLR4 cascade TAS Reactome
MyD88:MAL(TIRAP) cascade initiated on plasma membrane TAS Reactome
Myoclonic epilepsy of Lafora TAS Reactome
N-glycan trimming in the ER and Calnexin/Calreticulin cycle TAS Reactome
Neddylation TAS Reactome
Negative regulation of FGFR1 signaling TAS Reactome
Negative regulation of FGFR2 signaling TAS Reactome
Negative regulation of FGFR3 signaling TAS Reactome
Negative regulation of FGFR4 signaling TAS Reactome
Negative regulation of FLT3 TAS Reactome
Negative regulation of MAPK pathway TAS Reactome
Negative regulation of MET activity TAS Reactome
Negative regulation of NOTCH4 signaling IEA Reactome
Negative regulators of DDX58/IFIH1 signaling TAS Reactome
Nervous system development TAS Reactome
Nervous system development IEA Reactome
NF-kB is activated and signals survival TAS Reactome
NIK-->noncanonical NF-kB signaling TAS Reactome
NOD1/2 Signaling Pathway TAS Reactome
NOTCH1 Intracellular Domain Regulates Transcription IEA Reactome
NOTCH2 Activation and Transmission of Signal to the Nucleus IEA Reactome
NOTCH3 Activation and Transmission of Signal to the Nucleus IEA Reactome
NOTCH3 Activation and Transmission of Signal to the Nucleus TAS Reactome
NRIF signals cell death from the nucleus TAS Reactome
Nuclear events mediated by NFE2L2 TAS Reactome
Nucleotide Excision Repair TAS Reactome
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways TAS Reactome
Oncogene Induced Senescence TAS Reactome
Orc1 removal from chromatin TAS Reactome
Ovarian tumor domain proteases TAS Reactome
Oxidative Stress Induced Senescence TAS Reactome
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha TAS Reactome
p53-Dependent G1 DNA Damage Response TAS Reactome
p53-Dependent G1/S DNA damage checkpoint TAS Reactome
p53-Independent DNA Damage Response TAS Reactome
p53-Independent G1/S DNA damage checkpoint TAS Reactome
p75 NTR receptor-mediated signalling TAS Reactome
p75NTR recruits signalling complexes TAS Reactome
p75NTR signals via NF-kB TAS Reactome
PCP/CE pathway TAS Reactome
Peroxisomal protein import IEA Reactome
Peroxisomal protein import TAS Reactome
Pexophagy TAS Reactome
PINK1-PRKN Mediated Mitophagy TAS Reactome
PIP3 activates AKT signaling TAS Reactome
Plasma lipoprotein assembly, remodeling, and clearance TAS Reactome
Plasma lipoprotein clearance TAS Reactome
Post-translational protein modification TAS Reactome
Post-translational protein modification IEA Reactome
Prevention of phagosomal-lysosomal fusion TAS Reactome
Processing of DNA double-strand break ends TAS Reactome
Programmed Cell Death IEA Reactome
Programmed Cell Death TAS Reactome
Protein localization IEA Reactome
Protein localization TAS Reactome
Protein ubiquitination TAS Reactome
Protein ubiquitination IEA Reactome
PTEN Regulation TAS Reactome
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 TAS Reactome
Pyruvate metabolism TAS Reactome
RAF/MAP kinase cascade TAS Reactome
RAS processing TAS Reactome
Recognition of DNA damage by PCNA-containing replication complex TAS Reactome
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks TAS Reactome
Regulated Necrosis TAS Reactome
Regulation of activated PAK-2p34 by proteasome mediated degradation IEA Reactome
Regulation of APC/C activators between G1/S and early anaphase TAS Reactome
Regulation of Apoptosis IEA Reactome
Regulation of BACH1 activity TAS Reactome
Regulation of expression of SLITs and ROBOs TAS Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Regulation of FZD by ubiquitination TAS Reactome
Regulation of innate immune responses to cytosolic DNA TAS Reactome
Regulation of mitotic cell cycle TAS Reactome
Regulation of mRNA stability by proteins that bind AU-rich elements TAS Reactome
Regulation of necroptotic cell death TAS Reactome
Regulation of NF-kappa B signaling TAS Reactome
Regulation of PLK1 Activity at G2/M Transition TAS Reactome
Regulation of PTEN localization TAS Reactome
Regulation of PTEN stability and activity TAS Reactome
Regulation of pyruvate metabolism TAS Reactome
Regulation of RAS by GAPs TAS Reactome
Regulation of RUNX2 expression and activity IEA Reactome
Regulation of RUNX2 expression and activity TAS Reactome
Regulation of RUNX3 expression and activity TAS Reactome
Regulation of signaling by CBL TAS Reactome
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 TAS Reactome
Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation TAS Reactome
Regulation of TNFR1 signaling TAS Reactome
Regulation of TP53 Activity TAS Reactome
Regulation of TP53 Activity through Methylation TAS Reactome
Regulation of TP53 Activity through Phosphorylation TAS Reactome
Regulation of TP53 Degradation TAS Reactome
Regulation of TP53 Expression and Degradation TAS Reactome
Respiratory Syncytial Virus Infection Pathway TAS Reactome
Response of Mtb to phagocytosis TAS Reactome
RIPK1-mediated regulated necrosis TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RNA Polymerase II Transcription IEA Reactome
RSV-host interactions TAS Reactome
RUNX1 regulates transcription of genes involved in differentiation of HSCs TAS Reactome
S Phase TAS Reactome
SARS-CoV Infections TAS Reactome
SARS-CoV Infections IEA Reactome
SARS-CoV-1 activates/modulates innate immune responses TAS Reactome
SARS-CoV-1 Infection TAS Reactome
SARS-CoV-1-host interactions TAS Reactome
SARS-CoV-2 activates/modulates innate and adaptive immune responses TAS Reactome
SARS-CoV-2 Infection TAS Reactome
SARS-CoV-2 Infection IEA Reactome
SARS-CoV-2-host interactions TAS Reactome
SCF(Skp2)-mediated degradation of p27/p21 TAS Reactome
SCF-beta-TrCP mediated degradation of Emi1 TAS Reactome
Selective autophagy TAS Reactome
Selective autophagy IEA Reactome
Senescence-Associated Secretory Phenotype (SASP) TAS Reactome
Separation of Sister Chromatids TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by ALK fusions and activated point mutants TAS Reactome
Signaling by ALK in cancer TAS Reactome
Signaling by CSF1 (M-CSF) in myeloid cells IEA Reactome
Signaling by CSF3 (G-CSF) TAS Reactome
Signaling by EGFR TAS Reactome
Signaling by EGFR in Cancer TAS Reactome
Signaling by ERBB2 TAS Reactome
Signaling by ERBB4 TAS Reactome
Signaling by FGFR TAS Reactome
Signaling by FGFR1 TAS Reactome
Signaling by FGFR2 TAS Reactome
Signaling by FGFR3 TAS Reactome
Signaling by FGFR4 TAS Reactome
Signaling by Hedgehog TAS Reactome
Signaling by Hedgehog IEA Reactome
Signaling by Interleukins TAS Reactome
Signaling by Ligand-Responsive EGFR Variants in Cancer TAS Reactome
Signaling by MET TAS Reactome
Signaling by Non-Receptor Tyrosine Kinases TAS Reactome
Signaling by NOTCH IEA Reactome
Signaling by NOTCH TAS Reactome
Signaling by NOTCH1 IEA Reactome
Signaling by NOTCH1 TAS Reactome
Signaling by NOTCH1 HD Domain Mutants in Cancer TAS Reactome
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer TAS Reactome
Signaling by NOTCH1 in Cancer TAS Reactome
Signaling by NOTCH1 PEST Domain Mutants in Cancer TAS Reactome
Signaling by NOTCH2 IEA Reactome
Signaling by NOTCH3 IEA Reactome
Signaling by NOTCH3 TAS Reactome
Signaling by NOTCH4 IEA Reactome
Signaling by PTK6 TAS Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by ROBO receptors TAS Reactome
Signaling by ROBO receptors IEA Reactome
Signaling by TGF-beta Receptor Complex TAS Reactome
Signaling by TGF-beta Receptor Complex IEA Reactome
Signaling by TGFB family members TAS Reactome
Signaling by TGFB family members IEA Reactome
Signaling by the B Cell Receptor (BCR) TAS Reactome
Signaling by WNT TAS Reactome
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription IEA Reactome
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription TAS Reactome
Spry regulation of FGF signaling TAS Reactome
Stabilization of p53 TAS Reactome
Stimuli-sensing channels TAS Reactome
Suppression of phagosomal maturation TAS Reactome
Switching of origins to a post-replicative state TAS Reactome
Synthesis And Processing Of GAG, GAGPOL Polyproteins TAS Reactome
Synthesis of active ubiquitin: roles of E1 and E2 enzymes TAS Reactome
Synthesis of active ubiquitin: roles of E1 and E2 enzymes IEA Reactome
Synthesis of DNA TAS Reactome
TAK1-dependent IKK and NF-kappa-B activation TAS Reactome
TCF dependent signaling in response to WNT TAS Reactome
TCR signaling TAS Reactome
Termination of translesion DNA synthesis TAS Reactome
TGF-beta receptor signaling activates SMADs IEA Reactome
TGF-beta receptor signaling activates SMADs TAS Reactome
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) TAS Reactome
The role of GTSE1 in G2/M progression after G2 checkpoint TAS Reactome
TICAM1, RIP1-mediated IKK complex recruitment TAS Reactome
TICAM1,TRAF6-dependent induction of TAK1 complex TAS Reactome
TICAM1-dependent activation of IRF3/IRF7 TAS Reactome
TNF signaling TAS Reactome
TNFR1-induced NF-kappa-B signaling pathway TAS Reactome
TNFR2 non-canonical NF-kB pathway TAS Reactome
Toll Like Receptor 10 (TLR10) Cascade TAS Reactome
Toll Like Receptor 2 (TLR2) Cascade TAS Reactome
Toll Like Receptor 3 (TLR3) Cascade TAS Reactome
Toll Like Receptor 4 (TLR4) Cascade TAS Reactome
Toll Like Receptor 5 (TLR5) Cascade TAS Reactome
Toll Like Receptor 7/8 (TLR7/8) Cascade TAS Reactome
Toll Like Receptor 9 (TLR9) Cascade TAS Reactome
Toll Like Receptor TLR1:TLR2 Cascade TAS Reactome
Toll Like Receptor TLR6:TLR2 Cascade TAS Reactome
Toll-like Receptor Cascades TAS Reactome
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation TAS Reactome
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling TAS Reactome
TRAF6-mediated induction of TAK1 complex within TLR4 complex TAS Reactome
Transcription-Coupled Nucleotide Excision Repair (TC-NER) TAS Reactome
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer TAS Reactome
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer IEA Reactome
Transcriptional regulation by RUNX1 TAS Reactome
Transcriptional regulation by RUNX2 IEA Reactome
Transcriptional regulation by RUNX2 TAS Reactome
Transcriptional regulation by RUNX3 TAS Reactome
Transcriptional Regulation by TP53 TAS Reactome
Translation of Structural Proteins TAS Reactome
Translation of Structural Proteins IEA Reactome
Translesion Synthesis by POLH TAS Reactome
Translesion synthesis by POLI TAS Reactome
Translesion synthesis by POLK TAS Reactome
Translesion synthesis by REV1 TAS Reactome
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template TAS Reactome
Transport of small molecules TAS Reactome
TRIF (TICAM1)-mediated TLR4 signaling TAS Reactome
Ub-specific processing proteases TAS Reactome
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A TAS Reactome
Ubiquitin-dependent degradation of Cyclin D TAS Reactome
UCH proteinases IEA Reactome
UCH proteinases TAS Reactome
Vesicle-mediated transport TAS Reactome
Vif-mediated degradation of APOBEC3G TAS Reactome
Viral Infection Pathways TAS Reactome
Viral Infection Pathways IEA Reactome
VLDLR internalisation and degradation TAS Reactome
Vpu mediated degradation of CD4 TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here