Gene description for H2AFZ
Gene name H2A histone family, member Z
Gene symbol H2AFZ
Other names/aliases H2A.Z-1
H2A.z
H2A/z
H2AZ
Species Homo sapiens
 Database cross references - H2AFZ
ExoCarta ExoCarta_3015
Vesiclepedia VP_3015
Entrez Gene 3015
HGNC 4741
MIM 142763
UniProt P0C0S5  
 H2AFZ identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Neuroblastoma cells 25944692    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Thymus 23844026    
 Gene ontology annotations for H2AFZ
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 IDA
    protein binding GO:0005515 IPI
    structural constituent of chromatin GO:0030527 IBA
    chromatin DNA binding GO:0031490 IDA
    nucleosomal DNA binding GO:0031492 IDA
    protein heterodimerization activity GO:0046982 IEA
Biological Process
    chromatin organization GO:0006325 NAS
    heterochromatin formation GO:0031507 IBA
    positive regulation of transcription by RNA polymerase II GO:0045944 IMP
    cellular response to estradiol stimulus GO:0071392 IMP
Subcellular Localization
    nucleosome GO:0000786 IBA
    nucleosome GO:0000786 IPI
    euchromatin GO:0000791 IDA
    heterochromatin GO:0000792 IDA
    Barr body GO:0001740 IDA
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified H2AFZ in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
10
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
11
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
12
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
13
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for H2AFZ
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
3 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 BAHD1  
Affinity Capture-MS Homo sapiens
5 MCM7 4176
Affinity Capture-MS Homo sapiens
6 HIST1H4K 8362
Affinity Capture-Western Homo sapiens
7 CDC26 246184
Affinity Capture-MS Homo sapiens
8 RFC1 5981
Affinity Capture-MS Homo sapiens
9 MSL1 339287
Affinity Capture-MS Homo sapiens
10 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
11 CBX1 10951
Affinity Capture-MS Homo sapiens
12 ZNHIT1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 MBTD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 HDAC2 3066
Affinity Capture-MS Homo sapiens
15 ARID5B 84159
Affinity Capture-MS Homo sapiens
16 JMJD1C 221037
Affinity Capture-MS Homo sapiens
17 VAPA 9218
Affinity Capture-MS Homo sapiens
18 YEATS4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 TRRAP 8295
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 JADE3  
Affinity Capture-MS Homo sapiens
21 XPC  
Affinity Capture-MS Homo sapiens
22 BTF3 689
Affinity Capture-MS Homo sapiens
23 TPX2  
Affinity Capture-MS Homo sapiens
24 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 PBRM1 55193
Affinity Capture-MS Homo sapiens
26 ACTC1 70
Proximity Label-MS Homo sapiens
27 HIST1H2BJ 8970
Cross-Linking-MS (XL-MS) Homo sapiens
28 NSD1  
Affinity Capture-MS Homo sapiens
29 HIST1H4D 8360
Affinity Capture-Western Homo sapiens
30 KIF20A 10112
Affinity Capture-MS Homo sapiens
31 USP16  
Biochemical Activity Homo sapiens
32 MAP4K4 9448
Affinity Capture-MS Homo sapiens
33 HIST3H2BB 128312
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 SAP30 8819
Affinity Capture-MS Homo sapiens
35 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
36 INCENP 3619
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
37 KDM4A  
Affinity Capture-MS Homo sapiens
38 ZBTB1  
Affinity Capture-MS Homo sapiens
39 PRKDC 5591
Affinity Capture-MS Homo sapiens
40 ANP32B 10541
Affinity Capture-MS Homo sapiens
41 CENPA  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
42 JAZF1  
Affinity Capture-MS Homo sapiens
43 USP36  
Affinity Capture-MS Homo sapiens
44 RAI1 10743
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 PSIP1 11168
Affinity Capture-MS Homo sapiens
46 WTAP 9589
Affinity Capture-MS Homo sapiens
47 DDX23 9416
Proximity Label-MS Homo sapiens
48 EPC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 RUVBL1 8607
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 SRCAP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 GATAD2B 57459
Affinity Capture-MS Homo sapiens
52 MEAF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 C11orf30  
Affinity Capture-MS Homo sapiens
54 VPS72  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 KIF23 9493
Affinity Capture-MS Homo sapiens
56 MCM2 4171
Affinity Capture-MS Homo sapiens
57 DDB1 1642
Affinity Capture-MS Homo sapiens
58 SMARCA1 6594
Affinity Capture-MS Homo sapiens
59 H2AFV 94239
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
60 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
61 ING3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 PRC1 9055
Affinity Capture-MS Homo sapiens
63 ARID4B  
Affinity Capture-MS Homo sapiens
64 PSMD9 5715
Co-fractionation Homo sapiens
65 MRPL12 6182
Cross-Linking-MS (XL-MS) Homo sapiens
66 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
67 MED27  
Affinity Capture-MS Homo sapiens
68 ASB9  
Affinity Capture-MS Homo sapiens
69 OBSL1 23363
Affinity Capture-MS Homo sapiens
70 SMC2 10592
Affinity Capture-Western Homo sapiens
71 MCM6 4175
Affinity Capture-MS Homo sapiens
72 HMGA1 3159
Affinity Capture-MS Homo sapiens
73 NOL3 8996
Co-fractionation Homo sapiens
74 ZNF644  
Affinity Capture-MS Homo sapiens
75 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
76 CDC27 996
Affinity Capture-MS Homo sapiens
77 BCOR  
Affinity Capture-MS Homo sapiens
78 ASH2L 9070
Affinity Capture-MS Homo sapiens
79 HP1BP3 50809
Affinity Capture-MS Homo sapiens
80 NAP1L4 4676
Affinity Capture-MS Homo sapiens
81 WIZ 58525
Affinity Capture-MS Homo sapiens
82 H2AFY2 55506
Affinity Capture-MS Homo sapiens
83 WDR5 11091
Affinity Capture-MS Homo sapiens
84 NCK1 4690
Affinity Capture-MS Homo sapiens
85 HIST1H4G 8369
Affinity Capture-Western Homo sapiens
86 CLGN 1047
Cross-Linking-MS (XL-MS) Homo sapiens
87 ZNF280C  
Affinity Capture-MS Homo sapiens
88 MTA2 9219
Affinity Capture-MS Homo sapiens
89 MTA1 9112
Affinity Capture-MS Homo sapiens
90 USP37  
Proximity Label-MS Homo sapiens
91 KIF14 9928
Affinity Capture-MS Homo sapiens
92 DYNC1H1 1778
Cross-Linking-MS (XL-MS) Homo sapiens
93 KANSL1  
Affinity Capture-MS Homo sapiens
94 COMMD3-BMI1 100532731
Affinity Capture-MS Homo sapiens
95 H2AFZ 3015
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
96 ZMYM3  
Affinity Capture-MS Homo sapiens
97 PHF10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 HMGXB4 10042
Affinity Capture-MS Homo sapiens
99 RBBP7 5931
Affinity Capture-MS Homo sapiens
100 CDYL 9425
Affinity Capture-MS Homo sapiens
101 UBQLN1 29979
Affinity Capture-MS Homo sapiens
102 HIST1H4A 8359
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
103 RFC5 5985
Affinity Capture-MS Homo sapiens
104 SMARCA5 8467
Affinity Capture-MS Homo sapiens
105 HIST1H4E 8367
Affinity Capture-Western Homo sapiens
106 KAT7  
Affinity Capture-MS Homo sapiens
107 PHF14 9678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 MAGEC1  
Two-hybrid Homo sapiens
109 CBX3 11335
Affinity Capture-MS Homo sapiens
110 CFDP1  
Affinity Capture-MS Homo sapiens
111 ACACA 31
Negative Genetic Homo sapiens
112 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
113 SMARCA4 6597
Affinity Capture-MS Homo sapiens
114 CHMP4B 128866
Affinity Capture-MS Homo sapiens
115 POGZ 23126
Affinity Capture-MS Homo sapiens
116 SRBD1  
Affinity Capture-MS Homo sapiens
117 RNF168  
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
118 DPF2  
Affinity Capture-MS Homo sapiens
119 ACTL6A 86
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 CBX5 23468
Affinity Capture-MS Homo sapiens
121 XRCC5 7520
Affinity Capture-MS Homo sapiens
122 SUZ12  
Affinity Capture-MS Homo sapiens
123 BANF1 8815
Affinity Capture-MS Homo sapiens
124 FH 2271
Co-fractionation Homo sapiens
125 RFC4 5984
Affinity Capture-MS Homo sapiens
126 SUDS3  
Affinity Capture-MS Homo sapiens
127 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
128 NECAP1 25977
Affinity Capture-MS Homo sapiens
129 H2AFY 9555
Affinity Capture-MS Homo sapiens
130 PPM1G 5496
Affinity Capture-MS Homo sapiens
131 RYBP  
Affinity Capture-MS Homo sapiens
132 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
133 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
134 IPO9 55705
Affinity Capture-MS Homo sapiens
135 SMARCC2 6601
Affinity Capture-MS Homo sapiens
136 CD3EAP  
Proximity Label-MS Homo sapiens
137 KPNA1 3836
Affinity Capture-MS Homo sapiens
138 ZMYM4  
Affinity Capture-MS Homo sapiens
139 ANLN 54443
Affinity Capture-MS Homo sapiens
140 OGFOD1  
Co-fractionation Homo sapiens
141 BRD7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 NUMA1 4926
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 MIER3 166968
Affinity Capture-MS Homo sapiens
144 HIST1H4H 8365
Affinity Capture-Western Homo sapiens
145 MIER1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 HIST1H3A 8350
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
147 SMARCE1 6605
Affinity Capture-MS Homo sapiens
148 METTL14  
Affinity Capture-MS Homo sapiens
149 TARBP1 6894
Cross-Linking-MS (XL-MS) Homo sapiens
150 BAZ1B 9031
Affinity Capture-MS Homo sapiens
151 HIST2H3C 126961
Cross-Linking-MS (XL-MS) Homo sapiens
152 LMNB1 4001
Proximity Label-MS Homo sapiens
153 RC3H2  
Affinity Capture-MS Homo sapiens
154 ECT2 1894
Affinity Capture-MS Homo sapiens
155 NCKAP1 10787
Affinity Capture-MS Homo sapiens
156 RLIM 51132
Affinity Capture-MS Homo sapiens
157 HCFC1 3054
Affinity Capture-MS Homo sapiens
158 SMARCB1 6598
Affinity Capture-MS Homo sapiens
159 BRD8 10902
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 SUPT5H 6829
Affinity Capture-MS Homo sapiens
161 UBC 7316
Affinity Capture-MS Homo sapiens
162 PHF2  
Affinity Capture-MS Homo sapiens
163 BPTF 2186
Affinity Capture-MS Homo sapiens
164 ADNP 23394
Affinity Capture-MS Homo sapiens
165 H1F0 3005
Affinity Capture-MS Homo sapiens
166 EP400  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
167 RPL32 6161
Cross-Linking-MS (XL-MS) Homo sapiens
168 MORF4L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 ANP32E 81611
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 BRMS1L  
Affinity Capture-MS Homo sapiens
171 HIST1H2BO 8348
Affinity Capture-MS Homo sapiens
172 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
173 ASB16 92591
Affinity Capture-MS Homo sapiens
174 AURKB 9212
Affinity Capture-MS Homo sapiens
175 ACTR6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 HIST1H3B 8358
Affinity Capture-MS Homo sapiens
177 DMAP1 55929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 HIST1H4B 8366
Affinity Capture-Western Homo sapiens
179 MRGBP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 NCAPH 23397
Reconstituted Complex Homo sapiens
181 MYC  
Affinity Capture-MS Homo sapiens
182 HIST1H2BA 255626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
183 NAP1L1 4673
Affinity Capture-MS Homo sapiens
184 PHF6  
Affinity Capture-MS Homo sapiens
185 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
186 ING5  
Affinity Capture-MS Homo sapiens
187 EPN1 29924
Affinity Capture-MS Homo sapiens
188 TOP1 7150
Affinity Capture-MS Homo sapiens
189 EHMT2 10919
Affinity Capture-MS Homo sapiens
190 KAT5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 HIST1H4F 8361
Affinity Capture-Western Homo sapiens
192 BAZ1A 11177
Affinity Capture-MS Homo sapiens
193 ACTL6B  
Affinity Capture-MS Homo sapiens
194 CHD8 57680
Affinity Capture-MS Homo sapiens
195 HIST1H3I 8354
Affinity Capture-MS Homo sapiens
196 RNF2  
Affinity Capture-MS Homo sapiens
197 CBX2  
Affinity Capture-MS Homo sapiens
198 HIST1H4I 8294
Affinity Capture-Western Homo sapiens
199 TRNT1 51095
Co-fractionation Homo sapiens
200 RBBP5 5929
Affinity Capture-MS Homo sapiens
201 HMG20A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 LIG3 3980
Affinity Capture-MS Homo sapiens
203 UPF2 26019
Affinity Capture-MS Homo sapiens
204 BRD3 8019
Co-fractionation Homo sapiens
205 HIST1H2BI 8346
Affinity Capture-MS Homo sapiens
206 SUPT16H 11198
Affinity Capture-MS Homo sapiens
207 MDM2  
Affinity Capture-MS Homo sapiens
208 SIRT1  
Affinity Capture-MS Homo sapiens
209 RARG  
Affinity Capture-Western Homo sapiens
210 CCDC8  
Affinity Capture-MS Homo sapiens
211 H2AFX 3014
Co-localization Homo sapiens
212 GATAD2A 54815
Affinity Capture-MS Homo sapiens
213 TOP2B 7155
Affinity Capture-MS Homo sapiens
214 CTCF  
Affinity Capture-MS Homo sapiens
215 FASN 2194
Positive Genetic Homo sapiens
216 RSF1  
Affinity Capture-MS Homo sapiens
217 SIRT6  
Affinity Capture-MS Homo sapiens
218 PARP1 142
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 HMGN4  
Affinity Capture-MS Homo sapiens
220 ARID2  
Affinity Capture-MS Homo sapiens
221 HIST1H2AC 8334
Affinity Capture-MS Homo sapiens
222 SIN3A  
Affinity Capture-MS Homo sapiens
223 HIST2H2BC 337873
Affinity Capture-MS Homo sapiens
224 PYGL 5836
Co-fractionation Homo sapiens
225 WWOX 51741
Affinity Capture-MS Homo sapiens
226 ULBP2 80328
Cross-Linking-MS (XL-MS) Homo sapiens
227 NUCKS1 64710
Affinity Capture-MS Homo sapiens
228 MCM5 4174
Affinity Capture-MS Homo sapiens
229 SMARCC1 6599
Affinity Capture-MS Homo sapiens
230 APEX1 328
Proximity Label-MS Homo sapiens
231 EZR 7430
Co-fractionation Homo sapiens
232 CHAMP1  
Affinity Capture-MS Homo sapiens
233 RIF1  
Affinity Capture-MS Homo sapiens
234 DPY30 84661
Affinity Capture-MS Homo sapiens
235 ACAA2 10449
Co-fractionation Homo sapiens
236 ZNF512  
Affinity Capture-MS Homo sapiens
237 MSH6 2956
Affinity Capture-MS Homo sapiens
238 THRAP3 9967
Affinity Capture-MS Homo sapiens
239 MORF4L2  
Affinity Capture-MS Homo sapiens
240 NELFA  
Cross-Linking-MS (XL-MS) Homo sapiens
241 RUVBL2 10856
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
243 CHD1L 9557
Affinity Capture-MS Homo sapiens
244 DDX58 23586
Affinity Capture-RNA Homo sapiens
245 PARP2  
Affinity Capture-MS Homo sapiens
246 TOP2A 7153
Affinity Capture-MS Homo sapiens
247 ESR1  
Affinity Capture-MS Homo sapiens
248 INO80C  
Affinity Capture-MS Homo sapiens
249 CHRAC1  
Affinity Capture-MS Homo sapiens
250 YEATS2  
Affinity Capture-MS Homo sapiens
251 UBB 7314
Affinity Capture-MS Homo sapiens
252 HIST1H4L 8368
Affinity Capture-Western Homo sapiens
253 CHD4 1108
Affinity Capture-MS Homo sapiens
254 WDR48 57599
Affinity Capture-MS Homo sapiens
255 TCF20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
256 HIST1H4J 8363
Affinity Capture-Western Homo sapiens
257 SDC4 6385
Affinity Capture-MS Homo sapiens
258 MYO1E 4643
Affinity Capture-MS Homo sapiens
259 RCOR1  
Affinity Capture-MS Homo sapiens
260 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
261 XRCC6 2547
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
262 EHMT1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 KAT6A  
Affinity Capture-MS Homo sapiens
264 UHRF1 29128
Affinity Capture-MS Homo sapiens
265 C9orf72  
Affinity Capture-MS Homo sapiens
266 RPL36AL 6166
Affinity Capture-MS Homo sapiens
267 RC3H1 149041
Affinity Capture-MS Homo sapiens
268 PWWP2A  
Affinity Capture-MS Homo sapiens
269 SSRP1 6749
Affinity Capture-MS Homo sapiens
270 RBBP4 5928
Affinity Capture-MS Homo sapiens
271 C16orf87 388272
Affinity Capture-MS Homo sapiens
272 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
273 TXNDC2  
Affinity Capture-MS Homo sapiens
274 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
275 EPC2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which H2AFZ is involved
PathwayEvidenceSource
Amyloid fiber formation TAS Reactome
Metabolism of proteins TAS Reactome





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