Gene description for RPL35
Gene name ribosomal protein L35
Gene symbol RPL35
Other names/aliases L35
Species Homo sapiens
 Database cross references - RPL35
ExoCarta ExoCarta_11224
Vesiclepedia VP_11224
Entrez Gene 11224
HGNC 10344
UniProt P42766  
 RPL35 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Squamous carcinoma cells 20124223    
 Gene ontology annotations for RPL35
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA binding GO:0003729 IBA
    structural constituent of ribosome GO:0003735 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 NAS
Biological Process
    maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000463 IBA
    cytoplasmic translation GO:0002181 IC
    cytoplasmic translation GO:0002181 NAS
    translation GO:0006412 NAS
Subcellular Localization
    nucleolus GO:0005730 TAS
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    cytosolic large ribosomal subunit GO:0022625 HDA
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic ribosome GO:0022626 IDA
 Experiment description of studies that identified RPL35 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
20
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
21
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
22
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
26
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RPL35
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ARHGEF2 9181
Affinity Capture-MS Homo sapiens
2 ZBTB11  
Affinity Capture-MS Homo sapiens
3 AATF  
Affinity Capture-MS Homo sapiens
4 ZNF346  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 RIN3  
Affinity Capture-MS Homo sapiens
6 TOP2B 7155
Cross-Linking-MS (XL-MS) Homo sapiens
7 DDX21 9188
Affinity Capture-MS Homo sapiens
8 NMNAT1  
Affinity Capture-MS Homo sapiens
9 KIF20A 10112
Affinity Capture-MS Homo sapiens
10 MRPL27 51264
Affinity Capture-MS Homo sapiens
11 MRPS18C  
Affinity Capture-MS Homo sapiens
12 GPATCH4 54865
Affinity Capture-MS Homo sapiens
13 KIF23 9493
Affinity Capture-MS Homo sapiens
14 UBE2O 63893
Affinity Capture-MS Homo sapiens
15 SF3B1 23451
Affinity Capture-MS Homo sapiens
16 METAP2 10988
Affinity Capture-MS Homo sapiens
17 RPS9 6203
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
18 GSPT1 2935
Affinity Capture-MS Homo sapiens
19 RPF2 84154
Affinity Capture-MS Homo sapiens
20 FAM207A  
Cross-Linking-MS (XL-MS) Homo sapiens
21 SFN 2810
Affinity Capture-MS Homo sapiens
22 RPS11 6205
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
23 MRPL47 57129
Affinity Capture-MS Homo sapiens
24 RPL19 6143
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
25 KIF14 9928
Affinity Capture-MS Homo sapiens
26 CHMP4C 92421
Affinity Capture-MS Homo sapiens
27 RPL17 6139
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
28 KIFC1 3833
Affinity Capture-MS Homo sapiens
29 TARBP2  
Affinity Capture-MS Homo sapiens
30 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
31 MAPRE1 22919
Affinity Capture-MS Homo sapiens
32 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
33 RPL18A 6142
Co-fractionation Homo sapiens
34 PABPC1 26986
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
35 TRIM21 6737
Affinity Capture-MS Homo sapiens
36 RPL31 6160
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 NOC4L 79050
Affinity Capture-MS Homo sapiens
38 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
39 RRP1B 23076
Affinity Capture-MS Homo sapiens
40 PRKRIR  
Affinity Capture-MS Homo sapiens
41 MAGEB2 4113
Affinity Capture-MS Homo sapiens
42 RANBP6 26953
Affinity Capture-MS Homo sapiens
43 SND1 27044
Co-fractionation Homo sapiens
44 SEC61B 10952
Affinity Capture-MS Homo sapiens
45 SREK1 140890
Affinity Capture-MS Homo sapiens
46 MRPL41 64975
Affinity Capture-MS Homo sapiens
47 ANLN 54443
Affinity Capture-MS Homo sapiens
48 TMPO 7112
Affinity Capture-MS Homo sapiens
49 RBM39 9584
Affinity Capture-MS Homo sapiens
50 HADHB 3032
Affinity Capture-MS Homo sapiens
51 TMSB10 9168
Cross-Linking-MS (XL-MS) Homo sapiens
52 ABT1 29777
Affinity Capture-MS Homo sapiens
53 DAP3 7818
Affinity Capture-MS Homo sapiens
54 MRPL24  
Affinity Capture-MS Homo sapiens
55 MRPL16  
Affinity Capture-MS Homo sapiens
56 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 RAD18  
Affinity Capture-MS Homo sapiens
58 Fbxl16  
Affinity Capture-MS Mus musculus
59 PAPD5 64282
Affinity Capture-MS Homo sapiens
60 GADD45GIP1  
Affinity Capture-MS Homo sapiens
61 ATP1B3 483
Co-fractionation Homo sapiens
62 PRPSAP1 5635
Co-fractionation Homo sapiens
63 FN1 2335
Affinity Capture-MS Homo sapiens
64 ZNF512  
Affinity Capture-MS Homo sapiens
65 APOBEC3F 200316
Affinity Capture-MS Homo sapiens
66 RPA3 6119
Proximity Label-MS Homo sapiens
67 LTV1  
Affinity Capture-MS Homo sapiens
68 UBA52 7311
Co-fractionation Homo sapiens
69 RPL35A 6165
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
70 DDX54 79039
Affinity Capture-MS Homo sapiens
71 EIF3CL 728689
Co-fractionation Homo sapiens
72 PLCZ1  
Cross-Linking-MS (XL-MS) Homo sapiens
73 MRPL18 29074
Affinity Capture-MS Homo sapiens
74 RPS16 6217
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 U2SURP 23350
Affinity Capture-MS Homo sapiens
76 PKHD1L1 93035
Cross-Linking-MS (XL-MS) Homo sapiens
77 FTL 2512
Affinity Capture-MS Homo sapiens
78 TLX1  
Affinity Capture-MS Homo sapiens
79 YBX1 4904
Affinity Capture-MS Homo sapiens
80 RPS27A 6233
Cross-Linking-MS (XL-MS) Homo sapiens
81 FASN 2194
Positive Genetic Homo sapiens
82 PDE4B  
Protein-RNA Homo sapiens
83 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 MDK 4192
Affinity Capture-MS Homo sapiens
85 G3BP2 9908
Affinity Capture-MS Homo sapiens
86 KRR1 11103
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 LARP7 51574
Affinity Capture-MS Homo sapiens
88 RPS24 6229
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
89 NCL 4691
Affinity Capture-MS Homo sapiens
90 ZNF768 79724
Affinity Capture-MS Homo sapiens
91 CUL7 9820
Affinity Capture-MS Homo sapiens
92 MRPL55  
Affinity Capture-MS Homo sapiens
93 PURA 5813
Affinity Capture-MS Homo sapiens
94 MRPL28 10573
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 REPIN1  
Affinity Capture-MS Homo sapiens
96 SEC61A1 29927
Affinity Capture-MS Homo sapiens
97 PRKAA1 5562
Affinity Capture-MS Homo sapiens
98 MRPL48  
Affinity Capture-MS Homo sapiens
99 EIF2S3 1968
Affinity Capture-MS Homo sapiens
100 KIAA0020 9933
Affinity Capture-MS Homo sapiens
101 RPS17 6218
Affinity Capture-MS Homo sapiens
102 RSL24D1  
Affinity Capture-MS Homo sapiens
103 TARDBP 23435
Affinity Capture-MS Homo sapiens
104 BTF3 689
Affinity Capture-MS Homo sapiens
105 VPRBP 9730
Affinity Capture-MS Homo sapiens
106 RPL14 9045
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
107 MRPL50 54534
Affinity Capture-MS Homo sapiens
108 CAND1 55832
Affinity Capture-MS Homo sapiens
109 RSBN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 RPS3 6188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
111 RPS18 6222
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
112 RNPS1 10921
Co-fractionation Homo sapiens
113 B3GNT2 10678
Affinity Capture-MS Homo sapiens
114 DDX24 57062
Affinity Capture-MS Homo sapiens
115 H1FX 8971
Affinity Capture-MS Homo sapiens
116 RRP12 23223
Affinity Capture-MS Homo sapiens
117 PRC1 9055
Affinity Capture-MS Homo sapiens
118 MRPS23 51649
Affinity Capture-MS Homo sapiens
119 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
120 KRI1  
Affinity Capture-MS Homo sapiens
121 RPLP2 6181
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
122 PAK1IP1  
Affinity Capture-MS Homo sapiens
123 KLF4  
Affinity Capture-MS Homo sapiens
124 VCAM1 7412
Affinity Capture-MS Homo sapiens
125 DDX6 1656
Affinity Capture-MS Homo sapiens
126 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 RPL34 6164
Co-fractionation Homo sapiens
128 CUL1 8454
Affinity Capture-MS Homo sapiens
129 RBM42  
Affinity Capture-MS Homo sapiens
130 OASL 8638
Affinity Capture-MS Homo sapiens
131 TWF1 5756
Cross-Linking-MS (XL-MS) Homo sapiens
132 GAR1 54433
Affinity Capture-MS Homo sapiens
133 ZCRB1  
Affinity Capture-MS Homo sapiens
134 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
135 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
136 TRIM26 7726
Affinity Capture-MS Homo sapiens
137 MRPL45 84311
Affinity Capture-MS Homo sapiens
138 CDKN1A  
Two-hybrid Homo sapiens
139 RPL4 6124
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
140 DRG1 4733
Affinity Capture-MS Homo sapiens
141 MSX2  
Affinity Capture-MS Homo sapiens
142 VRK1 7443
Affinity Capture-MS Homo sapiens
143 TUBB2B 347733
Two-hybrid Homo sapiens
144 DDX10  
Affinity Capture-MS Homo sapiens
145 MRPS18B 28973
Affinity Capture-MS Homo sapiens
146 NKRF 55922
Affinity Capture-MS Homo sapiens
147 REXO4  
Affinity Capture-MS Homo sapiens
148 MRPL3  
Affinity Capture-MS Homo sapiens
149 Rrbp1  
Affinity Capture-MS Mus musculus
150 RPLP0 6175
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
151 DDX27 55661
Affinity Capture-MS Homo sapiens
152 CYLD  
Affinity Capture-MS Homo sapiens
153 C7orf50 84310
Affinity Capture-MS Homo sapiens
154 RSL1D1 26156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
156 RPS2 6187
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
157 MRPS35 60488
Affinity Capture-MS Homo sapiens
158 RC3H2  
Affinity Capture-MS Homo sapiens
159 MRPS11  
Affinity Capture-MS Homo sapiens
160 MRPL9 65005
Affinity Capture-MS Homo sapiens
161 EGFR 1956
Negative Genetic Homo sapiens
162 RPS27 6232
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
163 CDK2 1017
Affinity Capture-MS Homo sapiens
164 CEP250 11190
Affinity Capture-MS Homo sapiens
165 MYC  
Affinity Capture-MS Homo sapiens
166 CEBPZ  
Affinity Capture-MS Homo sapiens
167 SET 6418
Affinity Capture-MS Homo sapiens
168 RPL23A 6147
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 DDRGK1 65992
Affinity Capture-MS Homo sapiens
170 NOP16 51491
Affinity Capture-MS Homo sapiens
171 RPL26 6154
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
172 FTSJ3 117246
Affinity Capture-MS Homo sapiens
173 PA2G4 5036
Cross-Linking-MS (XL-MS) Homo sapiens
174 RPL13 6137
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
175 SURF6  
Affinity Capture-MS Homo sapiens
176 TXNDC16 57544
Affinity Capture-MS Homo sapiens
177 PARP1 142
Affinity Capture-MS Homo sapiens
178 ILF3 3609
Affinity Capture-MS Homo sapiens
179 HMGB1 3146
Cross-Linking-MS (XL-MS) Homo sapiens
180 FOLR1 2348
Affinity Capture-MS Homo sapiens
181 SRP19 6728
Affinity Capture-MS Homo sapiens
182 KNOP1 400506
Affinity Capture-MS Homo sapiens
183 RPS4X 6191
Co-fractionation Homo sapiens
184 UTP23  
Affinity Capture-MS Homo sapiens
185 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
186 RPS5 6193
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
187 NIFK 84365
Affinity Capture-MS Homo sapiens
188 MRPS21  
Affinity Capture-MS Homo sapiens
189 RPS26 6231
Co-fractionation Homo sapiens
190 SFSWAP  
Cross-Linking-MS (XL-MS) Homo sapiens
191 NOC2L 26155
Affinity Capture-MS Homo sapiens
192 RPSA 3921
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
193 YBX3 8531
Affinity Capture-MS Homo sapiens
194 RPL7A 6130
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
195 GLYR1 84656
Affinity Capture-MS Homo sapiens
196 KRAS 3845
Negative Genetic Homo sapiens
197 DDX31  
Affinity Capture-MS Homo sapiens
198 MRPS9 64965
Affinity Capture-MS Homo sapiens
199 RALY 22913
Affinity Capture-MS Homo sapiens
200 MRPS27 23107
Affinity Capture-MS Homo sapiens
201 UBE2H 7328
Affinity Capture-MS Homo sapiens
202 RPL26L1 51121
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 MRPL30  
Affinity Capture-MS Homo sapiens
204 MRPL17  
Affinity Capture-MS Homo sapiens
205 SP1  
Affinity Capture-MS Homo sapiens
206 SDAD1  
Affinity Capture-MS Homo sapiens
207 EPB41L5 57669
Affinity Capture-MS Homo sapiens
208 RPS19 6223
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
209 LUZP4  
Affinity Capture-MS Homo sapiens
210 SSB 6741
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 FAU 2197
Cross-Linking-MS (XL-MS) Homo sapiens
212 ATG13 9776
Affinity Capture-MS Homo sapiens
213 CAPZB 832
Affinity Capture-MS Homo sapiens
214 RPL10A 4736
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
215 WDR74 54663
Affinity Capture-MS Homo sapiens
216 CCDC137  
Affinity Capture-MS Homo sapiens
217 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
218 SSR1 6745
Affinity Capture-MS Homo sapiens
219 SRP14 6727
Affinity Capture-MS Homo sapiens
220 RC3H1 149041
Affinity Capture-MS Homo sapiens
221 ITGA4 3676
Affinity Capture-MS Homo sapiens
222 LOC101929876 101929876
Co-fractionation Homo sapiens
223 DDX18 8886
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
224 FAM111A 63901
Affinity Capture-MS Homo sapiens
225 RBM8A 9939
Affinity Capture-MS Homo sapiens
226 RBM19 9904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
227 FOXP1 27086
Protein-RNA Homo sapiens
228 LIN28A  
Affinity Capture-MS Homo sapiens
229 RPL27 6155
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
230 MRPS25 64432
Affinity Capture-MS Homo sapiens
231 RPL9 6133
Co-fractionation Homo sapiens
232 CUL4B 8450
Affinity Capture-MS Homo sapiens
233 PARK2  
Affinity Capture-MS Homo sapiens
234 RPS10 6204
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
235 ACACA 31
Positive Genetic Homo sapiens
236 RPL5 6125
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
237 ZCCHC3  
Affinity Capture-MS Homo sapiens
238 CHMP4B 128866
Affinity Capture-MS Homo sapiens
239 RPL36 25873
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
240 RPA4  
Proximity Label-MS Homo sapiens
241 RPN1 6184
Co-fractionation Homo sapiens
242 SGSM3  
Two-hybrid Homo sapiens
243 ENY2 56943
Affinity Capture-MS Homo sapiens
244 MRPL11 65003
Affinity Capture-MS Homo sapiens
245 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
246 MRPL2 51069
Affinity Capture-MS Homo sapiens
247 HMGB2 3148
Affinity Capture-MS Homo sapiens
248 HIST1H2AI 8329
Affinity Capture-MS Homo sapiens
249 LARP1 23367
Affinity Capture-MS Homo sapiens
250 WDR46  
Affinity Capture-MS Homo sapiens
251 Brwd3  
Affinity Capture-MS Mus musculus
252 LAMC3  
Two-hybrid Homo sapiens
253 SF3B2 10992
Affinity Capture-MS Homo sapiens
254 MRPL40 64976
Affinity Capture-MS Homo sapiens
255 ITPR2 3709
Cross-Linking-MS (XL-MS) Homo sapiens
256 METTL14  
Affinity Capture-MS Homo sapiens
257 CHERP 10523
Affinity Capture-MS Homo sapiens
258 ECT2 1894
Affinity Capture-MS Homo sapiens
259 MRPS14  
Affinity Capture-MS Homo sapiens
260 KPNB1 3837
Affinity Capture-MS Homo sapiens
261 HSP90AB1 3326
Cross-Linking-MS (XL-MS) Homo sapiens
262 RPL21 6144
Co-fractionation Homo sapiens
263 ZC3H8  
Affinity Capture-MS Homo sapiens
264 DHX30 22907
Affinity Capture-MS Homo sapiens
265 HNRNPUL1 11100
Cross-Linking-MS (XL-MS) Homo sapiens
266 TRANK1 9881
Cross-Linking-MS (XL-MS) Homo sapiens
267 NCAPH 23397
Affinity Capture-MS Homo sapiens
268 PSPC1 55269
Affinity Capture-MS Homo sapiens
269 RPS13 6207
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
270 RPS14 6208
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
271 RPL12 6136
Co-fractionation Homo sapiens
272 RPL22 6146
Co-fractionation Homo sapiens
273 HP1BP3 50809
Affinity Capture-MS Homo sapiens
274 ACTN2 88
Two-hybrid Homo sapiens
275 RPL18 6141
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
276 KTN1 3895
Affinity Capture-MS Homo sapiens
277 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 HDGF 3068
Affinity Capture-MS Homo sapiens
279 RBM17 84991
Affinity Capture-MS Homo sapiens
280 ZNF574  
Affinity Capture-MS Homo sapiens
281 DDX50 79009
Affinity Capture-MS Homo sapiens
282 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
283 RPS25 6230
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
284 MAX  
Reconstituted Complex Homo sapiens
285 FBXL6  
Affinity Capture-MS Homo sapiens
286 RPL6 6128
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
287 PDHA1 5160
Affinity Capture-MS Homo sapiens
288 G3BP1 10146
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
289 MRPS10 55173
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 CCT7 10574
Cross-Linking-MS (XL-MS) Homo sapiens
291 FKBP14  
Cross-Linking-MS (XL-MS) Homo sapiens
292 PDZD8 118987
Affinity Capture-MS Homo sapiens
293 UFL1 23376
Affinity Capture-MS Homo sapiens
294 RPL38 6169
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
295 API5 8539
Affinity Capture-MS Homo sapiens
296 GTPBP4 23560
Affinity Capture-MS Homo sapiens
297 ADH4  
Two-hybrid Homo sapiens
298 AKAP17A  
Affinity Capture-MS Homo sapiens
299 RPS7 6201
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
300 RPL8 6132
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
301 HNRNPF 3185
Cross-Linking-MS (XL-MS) Homo sapiens
302 RPL28 6158
Co-fractionation Homo sapiens
303 MRPS31  
Affinity Capture-MS Homo sapiens
304 RPL36AL 6166
Affinity Capture-MS Homo sapiens
305 RBM34  
Affinity Capture-MS Homo sapiens
306 PURB 5814
Affinity Capture-MS Homo sapiens
307 DDX56  
Affinity Capture-MS Homo sapiens
308 EIF5 1983
Affinity Capture-MS Homo sapiens
309 BOP1 23246
Affinity Capture-MS Homo sapiens
310 GNL2 29889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
311 CRBN  
Affinity Capture-MS Homo sapiens
312 RPS12 6206
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
313 RIT1 6016
Negative Genetic Homo sapiens
314 RPS3A 6189
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
315 RPL30 6156
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
316 IPO7 10527
Affinity Capture-MS Homo sapiens
317 RPL13A 23521
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
318 RPL37A 6168
Co-fractionation Homo sapiens
319 RPL10 6134
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
320 RPL15 6138
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
321 MRPL52  
Affinity Capture-MS Homo sapiens
322 COPS5 10987
Affinity Capture-MS Homo sapiens
323 TOP2A 7153
Affinity Capture-MS Homo sapiens
324 RPS20 6224
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
325 MRPL20 55052
Affinity Capture-MS Homo sapiens
326 TFAM 7019
Affinity Capture-MS Homo sapiens
327 PABPC4L 132430
Affinity Capture-MS Homo sapiens
328 MRPS5 64969
Affinity Capture-MS Homo sapiens
329 FBXW7  
Affinity Capture-MS Homo sapiens
330 RPL24 6152
Co-fractionation Homo sapiens
331 MRPS24 64951
Affinity Capture-MS Homo sapiens
332 MRPS26 64949
Affinity Capture-MS Homo sapiens
333 TTF1  
Affinity Capture-MS Homo sapiens
334 STAU2 27067
Affinity Capture-MS Homo sapiens
335 PRKRA 8575
Affinity Capture-MS Homo sapiens
336 SRP68 6730
Affinity Capture-MS Homo sapiens
337 NOC3L 64318
Affinity Capture-MS Homo sapiens
338 MYCN  
Affinity Capture-MS Homo sapiens
339 MAK16  
Affinity Capture-MS Homo sapiens
340 CTCF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
341 FCF1  
Affinity Capture-MS Homo sapiens
342 MRPS30 10884
Affinity Capture-MS Homo sapiens
343 SETD8  
Affinity Capture-MS Homo sapiens
344 RPS23 6228
Co-fractionation Homo sapiens
345 SRP9 6726
Affinity Capture-MS Homo sapiens
346 MRPL32 64983
Affinity Capture-MS Homo sapiens
347 COX15 1355
Affinity Capture-MS Homo sapiens
348 MRPS34 65993
Affinity Capture-MS Homo sapiens
349 HSP90B1 7184
Cross-Linking-MS (XL-MS) Homo sapiens
350 STAU1 6780
Affinity Capture-MS Homo sapiens
351 SRSF6 6431
Affinity Capture-MS Homo sapiens
352 PTCD3 55037
Affinity Capture-MS Homo sapiens
353 VCP 7415
Affinity Capture-MS Homo sapiens
354 RPL27A 6157
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
355 RPS15A 6210
Co-fractionation Homo sapiens
356 MRPS33  
Affinity Capture-MS Homo sapiens
357 GLTSCR2  
Affinity Capture-MS Homo sapiens
358 RPF1  
Affinity Capture-MS Homo sapiens
359 BMS1  
Affinity Capture-MS Homo sapiens
360 IPO5 3843
Affinity Capture-MS Homo sapiens
361 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
362 FANCD2  
Affinity Capture-MS Homo sapiens
363 RPL23 9349
Co-fractionation Homo sapiens
364 MRPL35  
Affinity Capture-MS Homo sapiens
365 DNAJC2 27000
Affinity Capture-MS Homo sapiens
366 NAT10 55226
Affinity Capture-MS Homo sapiens
367 RLIM 51132
Affinity Capture-MS Homo sapiens
368 RPS6 6194
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
369 RPL3 6122
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
370 NAP1L1 4673
Cross-Linking-MS (XL-MS) Homo sapiens
371 RPL7 6129
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
372 MRPL15 29088
Affinity Capture-MS Homo sapiens
373 AURKB 9212
Affinity Capture-MS Homo sapiens
374 PSTPIP1 9051
Affinity Capture-MS Homo sapiens
375 AGO4  
Affinity Capture-MS Homo sapiens
376 DKC1 1736
Affinity Capture-MS Homo sapiens
377 NIN 51199
Proximity Label-MS Homo sapiens
378 RPL7L1 285855
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
379 VDAC1 7416
Affinity Capture-MS Homo sapiens
380 RPL11 6135
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
381 MRPL46  
Affinity Capture-MS Homo sapiens
382 GNB2L1 10399
Affinity Capture-MS Homo sapiens
383 EIF3D 8664
Co-fractionation Homo sapiens
384 TRIM71  
Affinity Capture-MS Homo sapiens
385 MRPL42  
Affinity Capture-MS Homo sapiens
386 ARRB2 409
Affinity Capture-MS Homo sapiens
387 NEDD8 4738
Affinity Capture-MS Homo sapiens
388 BKRF1  
Affinity Capture-MS
389 RPL10L 140801
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
390 MINA 84864
Affinity Capture-MS Homo sapiens
391 NOL10  
Affinity Capture-MS Homo sapiens
392 ZNF746  
Affinity Capture-MS Homo sapiens
393 LGALS3 3958
Affinity Capture-MS Homo sapiens
394 Ccdc77  
Affinity Capture-MS Mus musculus
395 CUL5 8065
Affinity Capture-MS Homo sapiens
396 SMURF1 57154
Affinity Capture-MS Homo sapiens
397 RPS15 6209
Affinity Capture-MS Homo sapiens
398 SRP72 6731
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
399 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
400 NSA2  
Affinity Capture-MS Homo sapiens
401 MRPS18A  
Affinity Capture-MS Homo sapiens
402 RPS28 6234
Affinity Capture-MS Homo sapiens
403 MOV10 4343
Affinity Capture-MS Homo sapiens
404 MRPL13  
Affinity Capture-MS Homo sapiens
405 TRIP4 9325
Affinity Capture-MS Homo sapiens
406 TRIM31  
Affinity Capture-MS Homo sapiens
407 PINK1  
Affinity Capture-MS Homo sapiens
408 RPS8 6202
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
409 HNRNPU 3192
Co-fractionation Homo sapiens
410 C9orf72  
Affinity Capture-MS Homo sapiens
411 CLIC2 1193
Affinity Capture-MS Homo sapiens
412 ZNF770 54989
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RPL35 is involved
PathwayEvidenceSource
Axon guidance IEA Reactome
Cap-dependent Translation Initiation TAS Reactome
Cellular response to starvation IEA Reactome
Cellular responses to stimuli IEA Reactome
Cellular responses to stress IEA Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Eukaryotic Translation Elongation IEA Reactome
Eukaryotic Translation Initiation TAS Reactome
Eukaryotic Translation Termination IEA Reactome
Formation of a pool of free 40S subunits TAS Reactome
GTP hydrolysis and joining of the 60S ribosomal subunit TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
Influenza Viral RNA Transcription and Replication TAS Reactome
L13a-mediated translational silencing of Ceruloplasmin expression TAS Reactome
Major pathway of rRNA processing in the nucleolus and cytosol TAS Reactome
Metabolism IEA Reactome
Metabolism of amino acids and derivatives IEA Reactome
Metabolism of proteins TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of RNA TAS Reactome
Nervous system development IEA Reactome
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) TAS Reactome
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) TAS Reactome
Nonsense-Mediated Decay (NMD) TAS Reactome
Peptide chain elongation IEA Reactome
Regulation of expression of SLITs and ROBOs IEA Reactome
Response of EIF2AK4 (GCN2) to amino acid deficiency IEA Reactome
rRNA processing TAS Reactome
rRNA processing in the nucleus and cytosol TAS Reactome
Selenoamino acid metabolism IEA Reactome
Selenocysteine synthesis IEA Reactome
Signaling by ROBO receptors IEA Reactome
SRP-dependent cotranslational protein targeting to membrane IEA Reactome
SRP-dependent cotranslational protein targeting to membrane TAS Reactome
Translation TAS Reactome
Translation IEA Reactome
Viral Infection Pathways TAS Reactome
Viral mRNA Translation TAS Reactome





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