Experiment description of studies that identified UBR5 in exosomes

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

Protein-protein interactions for UBR5

Protein Interactor ExoCarta ID Identification method PubMed Species 1 DSN1 79980 Affinity Capture-MS Homo sapiens 2 MCRS1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 3 UBE2H 7328 Affinity Capture-MS Homo sapiens 4 OTUD5 55593 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Co-localization Homo sapiens 5 AFF4 27125 Co-fractionation Homo sapiens 6 HOOK1   Proximity Label-MS Homo sapiens 7 SPRTN   Affinity Capture-MS Homo sapiens 8 UBE2A   Reconstituted Complex Homo sapiens 9 EEF1G 1937 Co-fractionation Homo sapiens 10 PMS1   Affinity Capture-Western Homo sapiens 11 KPNA1 3836 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 12 BUB1   Affinity Capture-MS Homo sapiens 13 MSH2 4436 Co-fractionation Homo sapiens 14 WNK1 65125 Affinity Capture-Western Homo sapiens 15 ZBED6CL   Affinity Capture-MS Homo sapiens 16 TPD52L1 7164 Co-fractionation Homo sapiens 17 MOAP1   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Biochemical Activity Homo sapiens 18 VPRBP 9730 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Co-fractionation Homo sapiens 19 PDCD1   Affinity Capture-MS Homo sapiens 20 SUB1 10923 Affinity Capture-MS Homo sapiens 21 EBNA-LP   Affinity Capture-MS 22 DBN1 1627 Affinity Capture-MS Homo sapiens 23 BUB1B   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 24 UBC 7316 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Co-crystal Structure Homo sapiens 25 CCT4 10575 Affinity Capture-MS Homo sapiens 26 CHEK2   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 27 CALM1 801 Affinity Capture-Western Homo sapiens 28 VHL   Affinity Capture-MS Homo sapiens 29 ANKRD28 23243 Proximity Label-MS Homo sapiens 30 STX11 8676 Affinity Capture-MS Homo sapiens 31 EEF1A2 1917 Affinity Capture-MS Homo sapiens 32 ZNF207 7756 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 33 TCEA1 6917 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Co-localization Homo sapiens Affinity Capture-Western Homo sapiens 34 KIAA1429 25962 Affinity Capture-MS Homo sapiens 35 DPPA4   Affinity Capture-MS Homo sapiens 36 WTAP 9589 Affinity Capture-MS Homo sapiens 37 PPL 5493 Affinity Capture-MS Homo sapiens 38 NR1I2   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Biochemical Activity Homo sapiens 39 WDR48 57599 Affinity Capture-MS Homo sapiens 40 PGK1 5230 Affinity Capture-MS Homo sapiens 41 PFKL 5211 Co-fractionation Homo sapiens 42 TNRC6A 27327 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 43 GTF2E2   Affinity Capture-MS Homo sapiens 44 KIF23 9493 Affinity Capture-MS Homo sapiens 45 PCK1 5105 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 46 DYRK2 8445 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 47 GKN1   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 48 H2AFV 94239 Affinity Capture-MS Homo sapiens 49 TOB1   Affinity Capture-Western Homo sapiens 50 ACTR1A 10121 Co-fractionation Homo sapiens 51 F9 2158 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 POU5F1   Affinity Capture-MS Homo sapiens 53 MARCH5   Affinity Capture-MS Homo sapiens 54 PPEF1   Affinity Capture-MS Homo sapiens 55 PSMC2 5701 Co-fractionation Homo sapiens 56 Cenpe   Affinity Capture-MS Mus musculus 57 HNRNPU 3192 Co-fractionation Homo sapiens 58 MMP19 4327 Affinity Capture-MS Homo sapiens 59 MRS2   Affinity Capture-MS Homo sapiens 60 DNAJC16   Affinity Capture-MS Homo sapiens 61 POLDIP3 84271 Affinity Capture-MS Homo sapiens 62 Ubr5   Affinity Capture-MS Mus musculus 63 ASH2L 9070 Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 PMS2   Affinity Capture-MS Homo sapiens 65 APC   Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 66 ARPC1B 10095 Affinity Capture-MS Homo sapiens 67 Mcm3 17215 Affinity Capture-MS Mus musculus 68 CUL1 8454 Affinity Capture-MS Homo sapiens 69 HUWE1 10075 Affinity Capture-MS Homo sapiens 70 MRPL4 51073 Affinity Capture-MS Homo sapiens 71 WDR5 11091 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 72 FAF2 23197 Affinity Capture-MS Homo sapiens 73 TOB2   Affinity Capture-Western Homo sapiens 74 MAD2L1 4085 Affinity Capture-Western Homo sapiens 75 FBXW5   Affinity Capture-MS Homo sapiens 76 EEF1A1 1915 Co-fractionation Homo sapiens Co-fractionation Homo sapiens 77 GFI1B   Affinity Capture-MS Homo sapiens 78 GSK3B 2932 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 79 KIF14 9928 Affinity Capture-MS Homo sapiens 80 DDX58 23586 Affinity Capture-RNA Homo sapiens 81 NCOA1   Affinity Capture-MS Homo sapiens 82 AGO2 27161 Affinity Capture-Western Homo sapiens 83 MAPK1 5594 Biochemical Activity Homo sapiens Affinity Capture-Western Homo sapiens 84 DDX23 9416 Co-fractionation Homo sapiens 85 XPO1 7514 Affinity Capture-MS Homo sapiens 86 GEMIN5 25929 Affinity Capture-MS Homo sapiens 87 PPP1CA 5499 Reconstituted Complex Homo sapiens 88 RPS9 6203 Affinity Capture-MS Homo sapiens 89 NOLC1 9221 Co-fractionation Homo sapiens 90 BICD1 636 Proximity Label-MS Homo sapiens 91 TCP1 6950 Affinity Capture-MS Homo sapiens 92 MAPK3 5595 Affinity Capture-Western Homo sapiens 93 PRPF8 10594 Co-fractionation Homo sapiens 94 CAPZA1 829 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 95 GSPT1 2935 Affinity Capture-Western Homo sapiens 96 CTDP1 9150 Affinity Capture-MS Homo sapiens 97 CDKN1A   Affinity Capture-MS Homo sapiens 98 UTP15 84135 Co-fractionation Homo sapiens 99 SUPT5H 6829 Affinity Capture-MS Homo sapiens 100 NONO 4841 Affinity Capture-MS Homo sapiens 101 UBAP2L 9898 Affinity Capture-MS Homo sapiens 102 BAG6 7917 Affinity Capture-MS Homo sapiens 103 SNRNP200 23020 Co-fractionation Homo sapiens 104 TULP3 7289 Affinity Capture-MS Homo sapiens 105 UBR5 51366 Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens Biochemical Activity Homo sapiens 106 PABPC1 26986 Co-crystal Structure Homo sapiens 107 CHMP4B 128866 Affinity Capture-MS Homo sapiens 108 SREBF2 6721 Positive Genetic Homo sapiens 109 BARD1 580 Two-hybrid Homo sapiens 110 RNF168   Affinity Capture-Western Homo sapiens 111 SLX4   Affinity Capture-MS Homo sapiens 112 PTK2B 2185 Affinity Capture-Western Homo sapiens 113 FBXL6   Affinity Capture-MS Homo sapiens 114 PNMA2   Affinity Capture-MS Homo sapiens 115 SMAD2 4087 Two-hybrid Homo sapiens 116 CIB1 10519 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 117 DSP 1832 Affinity Capture-MS Homo sapiens 118 CRY2   Affinity Capture-MS Homo sapiens 119 PTRF 284119 Co-fractionation Homo sapiens 120 C19orf48   Affinity Capture-MS Homo sapiens 121 UBE2D3 7323 Reconstituted Complex Homo sapiens 122 C1orf115   Affinity Capture-MS Homo sapiens 123 IGFL3   Affinity Capture-MS Homo sapiens 124 DNAJC30   Affinity Capture-MS Homo sapiens 125 Bub1   Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus 126 UBE2B 7320 Reconstituted Complex Homo sapiens 127 RPS15A 6210 Affinity Capture-MS Homo sapiens 128 CEBPA   Affinity Capture-Western Homo sapiens Protein-peptide Homo sapiens Affinity Capture-Western Homo sapiens 129 GAR1 54433 Affinity Capture-MS Homo sapiens 130 MYH4   Affinity Capture-MS Homo sapiens 131 RPS6KA1 6195 Affinity Capture-Western Homo sapiens 132 VCP 7415 Affinity Capture-MS Homo sapiens 133 IGBP1 3476 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 134 TXN2 25828 Affinity Capture-Western Homo sapiens 135 HNRNPLL 92906 Affinity Capture-MS Homo sapiens 136 RING1 6015 Co-localization Homo sapiens 137 PHB 5245 Affinity Capture-MS Homo sapiens 138 RECQL5   Affinity Capture-MS Homo sapiens 139 ACTN1 87 Affinity Capture-MS Homo sapiens 140 HSPA5 3309 Co-fractionation Homo sapiens 141 TUBB 203068 Co-fractionation Homo sapiens 142 RRP1B 23076 Affinity Capture-MS Homo sapiens 143 TERT   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 144 FOXG1   Affinity Capture-MS Homo sapiens 145 CDC73   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 146 RPS2 6187 Affinity Capture-MS Homo sapiens 147 AMBRA1   Affinity Capture-MS Homo sapiens 148 CALR3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 149 SIRT7   Affinity Capture-MS Homo sapiens 150 UBXN7 26043 Affinity Capture-MS Homo sapiens 151 UQCRC2 7385 Co-fractionation Homo sapiens 152 UBE2L3 7332 Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 153 AURKA 6790 Affinity Capture-MS Homo sapiens 154 SRSF1 6426 Co-fractionation Homo sapiens 155 RPL14 9045 Affinity Capture-MS Homo sapiens 156 CUL3 8452 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 157 DUSP26 78986 Affinity Capture-MS Homo sapiens 158 XPNPEP3 63929 Affinity Capture-MS Homo sapiens 159 LYZL1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 160 C16orf72 29035 Affinity Capture-MS Homo sapiens 161 KIAA1524 57650 Two-hybrid Homo sapiens 162 METTL3   Affinity Capture-MS Homo sapiens 163 PGR   Reconstituted Complex Homo sapiens 164 ATMIN   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 165 SPTBN1 6711 Affinity Capture-MS Homo sapiens 166 WDR43 23160 Co-fractionation Homo sapiens 167 AURKB 9212 Affinity Capture-MS Homo sapiens 168 EFTUD2 9343 Co-fractionation Homo sapiens 169 SLC25A11 8402 Affinity Capture-MS Homo sapiens 170 UBE2D2 7322 Biochemical Activity Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 171 MAPK6   Affinity Capture-MS Homo sapiens 172 Igbp1 58845 Two-hybrid Rattus norvegicus 173 MYC   Affinity Capture-Western Homo sapiens Biochemical Activity Homo sapiens 174 ZUFSP 221302 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 175 NLRP3   Affinity Capture-MS Homo sapiens 176 SET 6418 Co-fractionation Homo sapiens 177 PRMT2   Affinity Capture-MS Homo sapiens 178 Cep78   Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus 179 ACTN4 81 Affinity Capture-MS Homo sapiens 180 TOLLIP 54472 Proximity Label-MS Homo sapiens 181 UBE2O 63893 Co-fractionation Homo sapiens 182 SERINC5 256987 Affinity Capture-MS Homo sapiens 183 DDB1 1642 Affinity Capture-Western Homo sapiens Co-fractionation Homo sapiens 184 PPAN 56342 Affinity Capture-MS Homo sapiens 185 Bub1b 12236 Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus 186 RPS11 6205 Affinity Capture-MS Homo sapiens 187 RNF2   Co-localization Homo sapiens 188 BMI1   Affinity Capture-MS Homo sapiens Co-localization Homo sapiens Affinity Capture-Western Homo sapiens 189 XRCC3   Affinity Capture-MS Homo sapiens 190 P4HA3 283208 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 191 POGLUT1 56983 Affinity Capture-MS Homo sapiens 192 PML 5371 Affinity Capture-MS Homo sapiens 193 Ostm1   Affinity Capture-MS Mus musculus Reconstituted Complex Mus musculus 194 SUPT16H 11198 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Co-localization Homo sapiens 195 UBXN1 51035 Affinity Capture-MS Homo sapiens 196 CCDC8   Affinity Capture-MS Homo sapiens 197 ACTBL2 345651 Affinity Capture-MS Homo sapiens 198 SATB1 6304 Two-hybrid Homo sapiens 199 UBE2D1 7321 Co-fractionation Homo sapiens 200 PAIP1 10605 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 201 NES 10763 Affinity Capture-MS Homo sapiens 202 DNAJC28   Affinity Capture-MS Homo sapiens 203 KIF2A 3796 Affinity Capture-MS Homo sapiens 204 ARRB2 409 Affinity Capture-MS Homo sapiens 205 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 206 FBXW11   Affinity Capture-Western Homo sapiens 207 SPTAN1 6709 Affinity Capture-MS Homo sapiens 208 CDC20 991 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 209 SIRT6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 210 MYL6 4637 Affinity Capture-MS Homo sapiens 211 PDGFD 80310 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 212 USP49 25862 Affinity Capture-MS Homo sapiens 213 TOPBP1 11073 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Biochemical Activity Homo sapiens 214 TP53 7157 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 215 KIF20A 10112 Affinity Capture-MS Homo sapiens 216 TUBG1 7283 Affinity Capture-MS Homo sapiens 217 EIF3I 8668 Co-fractionation Homo sapiens 218 RUVBL2 10856 Affinity Capture-MS Homo sapiens 219 FOXJ2   Affinity Capture-MS Homo sapiens 220 ZNF746   Affinity Capture-MS Homo sapiens 221 FOXB1   Affinity Capture-MS Homo sapiens 222 MEN1 4221 Affinity Capture-MS Homo sapiens 223 TUBGCP3 10426 Affinity Capture-MS Homo sapiens 224 NCOA2 10499 Affinity Capture-MS Homo sapiens 225 SHFM1 7979 Affinity Capture-MS Homo sapiens 226 CAPZB 832 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 227 KATNA1 11104 Affinity Capture-Western Homo sapiens 228 BUB3 9184 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 229 CEP250 11190 Affinity Capture-MS Homo sapiens 230 ATP6V1F 9296 Co-fractionation Homo sapiens 231 TRAP1 10131 Affinity Capture-MS Homo sapiens 232 RCOR1   Affinity Capture-MS Homo sapiens 233 DHX40   Proximity Label-MS Homo sapiens 234 MIF 4282 Affinity Capture-MS Homo sapiens 235 JAK3 3718 Affinity Capture-MS Homo sapiens 236 RNF38   Affinity Capture-MS Homo sapiens 237 TRIM37   Proximity Label-MS Homo sapiens 238 MRPS18B 28973 Co-fractionation Homo sapiens 239 MAGED1 9500 Affinity Capture-MS Homo sapiens 240 RANGAP1 5905 Co-fractionation Homo sapiens 241 ABHD10 55347 Affinity Capture-MS Homo sapiens 242 TMEM79   Affinity Capture-MS Homo sapiens 243 GSPT2 23708 Affinity Capture-Western Homo sapiens 244 CAD 790 Co-fractionation Homo sapiens 245 PRSS37   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 246 CDK9 1025 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Biochemical Activity Homo sapiens Co-localization Homo sapiens 247 DPF3   Affinity Capture-MS Homo sapiens 248 RPL8 6132 Affinity Capture-MS Homo sapiens 249 Mgp 17313 Affinity Capture-MS Mus musculus 250 BRD1 23774 Affinity Capture-MS Homo sapiens 251 C1QBP 708 Affinity Capture-MS Homo sapiens 252 ERG   Reconstituted Complex Homo sapiens 253 SNW1 22938 Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens 254 PAIP2   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 255 C9orf72   Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 256 AR 367 Affinity Capture-MS Homo sapiens 257 PSMB2 5690 Affinity Capture-MS Homo sapiens 258 ATOH1   Affinity Capture-MS Homo sapiens 259 SSRP1 6749 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 260 MATR3 9782 Co-fractionation Homo sapiens 261 FBXO38 81545 Proximity Label-MS Homo sapiens 262 RPA3 6119 Proximity Label-MS Homo sapiens 263 MAF   Affinity Capture-MS Homo sapiens 264 CEBPD   Affinity Capture-MS Homo sapiens 265 DDX28   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 266 CDC5L 988 Co-fractionation Homo sapiens 267 GTF2F2 2963 Co-fractionation Homo sapiens View the network

Pathways in which UBR5 is involved

No pathways found