Gene description for DDX5
Gene name DEAD (Asp-Glu-Ala-Asp) box helicase 5
Gene symbol DDX5
Other names/aliases G17P1
HLR1
HUMP68
p68
Species Homo sapiens
 Database cross references - DDX5
ExoCarta ExoCarta_1655
Vesiclepedia VP_1655
Entrez Gene 1655
HGNC 2746
MIM 180630
UniProt P17844  
 DDX5 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
 Gene ontology annotations for DDX5
Molecular Function
    DNA clamp loader activity GO:0003689 IEA
    RNA binding GO:0003723 HDA
    RNA helicase activity GO:0003724 IBA
    RNA helicase activity GO:0003724 IMP
    RNA helicase activity GO:0003724 NAS
    mRNA binding GO:0003729 IBA
    mRNA 3'-UTR binding GO:0003730 IDA
    protein binding GO:0005515 IPI
    calmodulin binding GO:0005516 IEA
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    enzyme binding GO:0019899 IEA
    MH2 domain binding GO:0035500 IPI
    pre-mRNA binding GO:0036002 IDA
    ribonucleoprotein complex binding GO:0043021 IDA
    SMAD binding GO:0046332 IPI
    calcium-dependent protein binding GO:0048306 IEA
    nuclear androgen receptor binding GO:0050681 IDA
    cohesin loader activity GO:0061775 IEA
    R-SMAD binding GO:0070412 IPI
    primary miRNA binding GO:0070878 IDA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
    promoter-specific chromatin binding GO:1990841 ISS
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    alternative mRNA splicing, via spliceosome GO:0000380 IBA
    alternative mRNA splicing, via spliceosome GO:0000380 IMP
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IDA
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IMP
    mRNA splicing, via spliceosome GO:0000398 IC
    nuclear-transcribed mRNA catabolic process GO:0000956 IDA
    epithelial to mesenchymal transition GO:0001837 IMP
    chromatin remodeling GO:0006338 IEA
    regulation of transcription by RNA polymerase II GO:0006357 IMP
    mRNA transcription GO:0009299 IMP
    BMP signaling pathway GO:0030509 IMP
    estrogen receptor signaling pathway GO:0030520 IMP
    androgen receptor signaling pathway GO:0030521 IMP
    primary miRNA processing GO:0031053 IMP
    positive regulation of DNA damage response, signal transduction by p53 class mediator GO:0043517 IMP
    regulation of viral genome replication GO:0045069 IEA
    myoblast differentiation GO:0045445 ISS
    regulation of osteoblast differentiation GO:0045667 ISS
    rhythmic process GO:0048511 IEA
    regulation of androgen receptor signaling pathway GO:0060765 IMP
    miRNA transcription GO:0061614 ISS
    intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 IMP
    chromatin looping GO:0140588 IEA
    regulation of miRNA transcription GO:1902893 IMP
    regulation of skeletal muscle cell differentiation GO:2001014 ISS
Subcellular Localization
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    nuclear speck GO:0016607 IDA
    extracellular exosome GO:0070062 HDA
    catalytic step 2 spliceosome GO:0071013 IDA
    ribonucleoprotein complex GO:1990904 IBA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified DDX5 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
12
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
24
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
31
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
33
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
45
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for DDX5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Cdk1 12534
Affinity Capture-MS Mus musculus
2 PPP1CB 5500
Co-fractionation Homo sapiens
3 HDAC2 3066
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
4 SHC1 6464
Affinity Capture-MS Homo sapiens
5 ERO1L 30001
Co-fractionation Homo sapiens
6 SKI 6497
Affinity Capture-MS Homo sapiens
7 CRK 1398
Affinity Capture-MS Homo sapiens
8 DDX17 10521
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
9 EBNA-LP  
Affinity Capture-Western
Affinity Capture-MS
10 KIF20A 10112
Affinity Capture-MS Homo sapiens
11 VHL  
Affinity Capture-MS Homo sapiens
12 PRPF40A 55660
Co-fractionation Homo sapiens
13 SOX2  
Affinity Capture-MS Homo sapiens
14 SBDS 51119
Co-fractionation Homo sapiens
15 CENPA  
Affinity Capture-MS Homo sapiens
16 APEX1 328
Affinity Capture-RNA Homo sapiens
17 FBXW4 6468
Affinity Capture-MS Homo sapiens
18 DDX23 9416
Proximity Label-MS Homo sapiens
19 IGF2BP3 10643
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
20 KIF23 9493
Affinity Capture-MS Homo sapiens
21 NDRG1 10397
Affinity Capture-MS Homo sapiens
22 FBXO46  
Affinity Capture-MS Homo sapiens
23 SF3B1 23451
Affinity Capture-MS Homo sapiens
24 AI837181  
Affinity Capture-MS Mus musculus
25 FBL 2091
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
26 SFN 2810
Affinity Capture-MS Homo sapiens
27 ZWINT  
Affinity Capture-MS Homo sapiens
28 MECP2 4204
Affinity Capture-MS Homo sapiens
29 FKBP10 60681
Co-fractionation Homo sapiens
30 RPL19 6143
Co-fractionation Homo sapiens
31 RBM14 10432
Affinity Capture-MS Homo sapiens
32 KIF14 9928
Affinity Capture-MS Homo sapiens
33 EMC9  
Affinity Capture-MS Homo sapiens
34 RBMX 27316
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
35 UNK  
Affinity Capture-RNA Homo sapiens
36 XRCC4  
Co-fractionation Homo sapiens
37 CHMP4C 92421
Affinity Capture-MS Homo sapiens
38 AURKA 6790
Affinity Capture-MS Homo sapiens
39 MTCH2 23788
Affinity Capture-MS Homo sapiens
40 DBNL 28988
Co-fractionation Homo sapiens
41 CAPZA1 829
Co-fractionation Homo sapiens
42 MEPCE 56257
Affinity Capture-MS Homo sapiens
43 SUPT5H 6829
Affinity Capture-MS Homo sapiens
44 PSME1 5720
Co-fractionation Homo sapiens
45 RPS6KB1 6198
Co-fractionation Homo sapiens
46 PABPC1 26986
Co-fractionation Homo sapiens
47 YAP1 10413
Affinity Capture-MS Homo sapiens
48 TYK2 7297
Affinity Capture-MS Homo sapiens
49 TRIM21 6737
Affinity Capture-MS Homo sapiens
50 SLX4  
Affinity Capture-MS Homo sapiens
51 RPL31 6160
Proximity Label-MS Homo sapiens
52 SYNCRIP 10492
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
53 HECTD1 25831
Affinity Capture-MS Homo sapiens
54 CUL2 8453
Affinity Capture-MS Homo sapiens
55 GTPBP4 23560
Co-fractionation Homo sapiens
56 SRPK1 6732
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
57 RMND5A 64795
Affinity Capture-MS Homo sapiens
58 CCNT1  
Affinity Capture-MS Homo sapiens
59 MGMT 4255
Affinity Capture-MS Homo sapiens
Co-localization Homo sapiens
60 ZNF326 284695
Affinity Capture-MS Homo sapiens
61 ANLN 54443
Affinity Capture-MS Homo sapiens
62 RNF40 9810
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
63 RBM39 9584
Affinity Capture-MS Homo sapiens
64 CD2BP2 10421
Affinity Capture-MS Homo sapiens
65 IFI16 3428
Affinity Capture-MS Homo sapiens
66 PRKAR1A 5573
Co-fractionation Homo sapiens
67 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 EPRS 2058
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
69 FN1 2335
Affinity Capture-MS Homo sapiens
70 TBP  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
71 CAMSAP2  
Co-fractionation Homo sapiens
72 PCBP1 5093
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
73 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
74 ILK 3611
Affinity Capture-MS Homo sapiens
75 AKT1 207
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
76 PRKDC 5591
Co-fractionation Homo sapiens
77 RPS16 6217
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
78 TNNT1  
Two-hybrid Homo sapiens
79 WDR77 79084
Affinity Capture-MS Homo sapiens
80 ZEB1  
Affinity Capture-MS Homo sapiens
81 CDC37 11140
Affinity Capture-MS Homo sapiens
82 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
83 RAB11FIP1 80223
Co-fractionation Homo sapiens
84 SGK2  
Affinity Capture-MS Homo sapiens
85 WWP2 11060
Affinity Capture-MS Homo sapiens
86 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
87 MCM5 4174
Affinity Capture-MS Homo sapiens
88 HDAC3 8841
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
89 NCL 4691
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
90 HNRNPL 3191
Affinity Capture-MS Homo sapiens
91 EIF4B 1975
Co-fractionation Homo sapiens
92 CYLD  
Affinity Capture-MS Homo sapiens
93 RDX 5962
Co-fractionation Homo sapiens
94 SNW1 22938
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
95 SYN1  
Co-fractionation Homo sapiens
96 SNRPA1 6627
Co-fractionation Homo sapiens
97 DERL1 79139
Affinity Capture-MS Homo sapiens
98 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
99 MCM3 4172
Co-fractionation Homo sapiens
100 LUZP4  
Affinity Capture-MS Homo sapiens
101 SPRTN  
Affinity Capture-MS Homo sapiens
102 MAGEA3  
Affinity Capture-MS Homo sapiens
103 KCTD10 83892
Affinity Capture-MS Homo sapiens
104 TARDBP 23435
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
105 DAPK1 1612
Affinity Capture-MS Homo sapiens
106 RPA2 6118
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
107 NACA 4666
Co-fractionation Homo sapiens
108 THRAP3 9967
Co-fractionation Homo sapiens
109 ZFR 51663
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
110 EIF4A1 1973
Co-fractionation Homo sapiens
111 CAND1 55832
Affinity Capture-MS Homo sapiens
112 SNRPF 6636
Affinity Capture-MS Homo sapiens
113 GFRA1 2674
Co-fractionation Homo sapiens
114 MAPK10 5602
Affinity Capture-MS Homo sapiens
115 WTAP 9589
Affinity Capture-MS Homo sapiens
116 TNK1  
Affinity Capture-MS Homo sapiens
117 B3GNT2 10678
Affinity Capture-MS Homo sapiens
118 COPS6 10980
Affinity Capture-MS Homo sapiens
119 PRC1 9055
Affinity Capture-MS Homo sapiens
120 SRRM2 23524
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
121 KHDRBS1 10657
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
122 OBSL1 23363
Affinity Capture-MS Homo sapiens
123 LRSAM1 90678
Co-fractionation Homo sapiens
124 U2AF1 7307
Co-fractionation Homo sapiens
125 VCAM1 7412
Affinity Capture-MS Homo sapiens
126 PFN2 5217
Co-fractionation Homo sapiens
127 PHF1  
Affinity Capture-MS Homo sapiens
128 CUL1 8454
Affinity Capture-MS Homo sapiens
129 RBM42  
Affinity Capture-MS Homo sapiens
130 FANCD2  
Affinity Capture-MS Homo sapiens
131 ATXN2 6311
Co-fractionation Homo sapiens
132 CCT2 10576
Co-fractionation Homo sapiens
133 GTF2I 2969
Co-fractionation Homo sapiens
134 IPO11 51194
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 HNRNPA0 10949
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
136 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
137 DDX21 9188
Affinity Capture-MS Homo sapiens
138 RBM6 10180
Affinity Capture-MS Homo sapiens
139 EIF2A 83939
Co-fractionation Homo sapiens
140 PSMD14 10213
Affinity Capture-MS Homo sapiens
141 VRK1 7443
Affinity Capture-MS Homo sapiens
142 C12orf49  
Negative Genetic Homo sapiens
143 CCT6A 908
Co-fractionation Homo sapiens
144 SNRPD1 6632
Co-fractionation Homo sapiens
145 NKRF 55922
Affinity Capture-MS Homo sapiens
146 NR2E1  
Affinity Capture-Western Homo sapiens
147 LUC7L2 51631
Co-fractionation Homo sapiens
148 Bag2  
Affinity Capture-MS Mus musculus
149 H19 283120
Protein-RNA Homo sapiens
150 GMPS 8833
Co-fractionation Homo sapiens
151 GET4 51608
Co-fractionation Homo sapiens
152 Ksr1  
Affinity Capture-MS Mus musculus
153 AIMP2 7965
Affinity Capture-MS Homo sapiens
154 NFX1  
Affinity Capture-MS Homo sapiens
155 CARS 833
Co-fractionation Homo sapiens
156 PSMA3 5684
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
157 SMARCAD1  
Affinity Capture-MS Homo sapiens
158 DHX36 170506
Co-fractionation Homo sapiens
159 XPO1 7514
Affinity Capture-MS Homo sapiens
160 IKZF3  
Affinity Capture-MS Homo sapiens
161 EGFR 1956
Affinity Capture-MS Homo sapiens
162 FUS 2521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
163 METTL3  
Affinity Capture-MS Homo sapiens
164 IKZF1  
Affinity Capture-MS Homo sapiens
165 RANBP9 10048
Affinity Capture-MS Homo sapiens
166 CDK2 1017
Affinity Capture-MS Homo sapiens
167 CEP250 11190
Affinity Capture-MS Homo sapiens
168 MAP2K3 5606
Affinity Capture-MS Homo sapiens
169 TADA2A  
Affinity Capture-MS Homo sapiens
170 PIAS1 8554
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
171 MYC  
Affinity Capture-MS Homo sapiens
172 DYNC1LI1 51143
Co-fractionation Homo sapiens
173 PRSS1 5644
Co-fractionation Homo sapiens
174 CUL7 9820
Affinity Capture-MS Homo sapiens
175 DDRGK1 65992
Affinity Capture-MS Homo sapiens
176 RNF43  
Proximity Label-MS Homo sapiens
177 EIF3F 8665
Affinity Capture-MS Homo sapiens
178 STK24 8428
Affinity Capture-MS Homo sapiens
179 SPOP  
Affinity Capture-MS Homo sapiens
180 HNRNPH2 3188
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
181 ILF3 3609
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
182 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 FOLR1 2348
Affinity Capture-MS Homo sapiens
184 AURKB 9212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 OTUB1 55611
Affinity Capture-MS Homo sapiens
186 NIFK 84365
Proximity Label-MS Homo sapiens
187 HNRNPK 3190
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
188 Bcas2  
Affinity Capture-MS Mus musculus
189 RAD50 10111
Co-fractionation Homo sapiens
190 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
191 GOLIM4 27333
Co-fractionation Homo sapiens
192 KHDRBS2  
Affinity Capture-MS Homo sapiens
193 DHX38 9785
Co-fractionation Homo sapiens
194 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
195 EP300 2033
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
196 KRAS 3845
Negative Genetic Homo sapiens
197 MAST3  
Affinity Capture-MS Homo sapiens
198 PRMT1 3276
Affinity Capture-MS Homo sapiens
199 CPSF6 11052
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
200 NUDT5 11164
Co-fractionation Homo sapiens
201 CUL4A 8451
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 TCP1 6950
Co-fractionation Homo sapiens
203 RALY 22913
Co-fractionation Homo sapiens
204 MCM7 4176
Co-fractionation Homo sapiens
205 UBE2H 7328
Affinity Capture-MS Homo sapiens
206 HNRNPC 3183
Affinity Capture-MS Homo sapiens
207 TCEB1 6921
Co-fractionation Homo sapiens
208 Fus  
Affinity Capture-MS Mus musculus
209 CTPS2 56474
Co-fractionation Homo sapiens
210 SP1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
211 CD4 920
Affinity Capture-MS Homo sapiens
212 SSB 6741
Co-fractionation Homo sapiens
213 TRMT6 51605
Co-fractionation Homo sapiens
214 HNRNPR 10236
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
215 PSMD10 5716
Co-fractionation Homo sapiens
216 RPS6KB2  
Affinity Capture-MS Homo sapiens
217 MYOD1  
Affinity Capture-Western Homo sapiens
218 ATG13 9776
Affinity Capture-MS Homo sapiens
219 CAPZB 832
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
220 DROSHA  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
221 TRIM28 10155
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
222 CTNNB1 1499
Co-fractionation Homo sapiens
223 MCM2 4171
Affinity Capture-MS Homo sapiens
224 EWSR1 2130
Co-fractionation Homo sapiens
225 SF3A2 8175
Affinity Capture-MS Homo sapiens
226 SRP14 6727
Co-fractionation Homo sapiens
227 ITGA4 3676
Affinity Capture-MS Homo sapiens
228 DDX18 8886
Co-fractionation Homo sapiens
229 TFCP2 7024
Affinity Capture-MS Homo sapiens
230 PABPC4 8761
Co-fractionation Homo sapiens
231 RBM8A 9939
Affinity Capture-MS Homo sapiens
232 PSME3 10197
Affinity Capture-MS Homo sapiens
233 VTN 7448
Co-fractionation Homo sapiens
234 CUL4B 8450
Affinity Capture-MS Homo sapiens
235 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 YPEL5 51646
Affinity Capture-MS Homo sapiens
237 ACACA 31
Positive Genetic Homo sapiens
238 CHMP4B 128866
Affinity Capture-MS Homo sapiens
239 BTF3 689
Affinity Capture-MS Homo sapiens
240 NTRK1 4914
Affinity Capture-MS Homo sapiens
241 U2AF2 11338
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
242 FLNB 2317
Co-fractionation Homo sapiens
243 RPA4  
Proximity Label-MS Homo sapiens
244 DHX9 1660
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
245 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
246 RYBP  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
247 RBM10  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
248 HNRNPDL 9987
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
249 OGT 8473
Reconstituted Complex Homo sapiens
250 AHCY 191
Co-fractionation Homo sapiens
251 METTL14  
Affinity Capture-MS Homo sapiens
252 ECT2 1894
Affinity Capture-MS Homo sapiens
253 EEF2 1938
Co-fractionation Homo sapiens
254 DTX2 113878
Proximity Label-MS Homo sapiens
255 YY1 7528
Affinity Capture-Western Homo sapiens
256 FBXO6 26270
Affinity Capture-MS Homo sapiens
257 HNRNPUL1 11100
Co-fractionation Homo sapiens
258 POLR2A 5430
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
259 PRPF19 27339
Co-fractionation Homo sapiens
260 PSPC1 55269
Affinity Capture-MS Homo sapiens
261 TOP1 7150
Affinity Capture-MS Homo sapiens
262 PIK3CA 5290
Two-hybrid Homo sapiens
263 SKIV2L2 23517
Co-fractionation Homo sapiens
264 MATR3 9782
Affinity Capture-MS Homo sapiens
265 RNF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
266 ARAF 369
Affinity Capture-MS Homo sapiens
267 HDGF 3068
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
268 CBX7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
269 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
270 CCT8 10694
Co-fractionation Homo sapiens
271 SMN1 6606
Affinity Capture-MS Homo sapiens
272 THUMPD3 25917
Co-fractionation Homo sapiens
273 ASF1B  
Co-fractionation Homo sapiens
274 PIN1 5300
Reconstituted Complex Homo sapiens
275 USP36  
Affinity Capture-MS Homo sapiens
276 RPA1 6117
Affinity Capture-MS Homo sapiens
277 SNRPA 6626
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
278 HNRNPM 4670
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
279 ABL1 25
Affinity Capture-MS Homo sapiens
280 CREBBP  
Affinity Capture-Western Homo sapiens
281 DDX58 23586
Affinity Capture-RNA Homo sapiens
282 CCT7 10574
Co-fractionation Homo sapiens
283 PDZD8 118987
Affinity Capture-MS Homo sapiens
284 UFL1 23376
Affinity Capture-MS Homo sapiens
285 MBNL1 4154
Affinity Capture-Western Homo sapiens
286 MED12  
Affinity Capture-MS Homo sapiens
287 HNRNPH3 3189
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
288 HNRNPF 3185
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
289 C14orf166 51637
Co-fractionation Homo sapiens
290 ERG  
Affinity Capture-MS Homo sapiens
291 SSRP1 6749
Affinity Capture-MS Homo sapiens
292 MAEA 10296
Affinity Capture-MS Homo sapiens
293 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 CRBN  
Affinity Capture-MS Homo sapiens
295 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
296 CCT3 7203
Co-fractionation Homo sapiens
297 SCARNA22  
Affinity Capture-RNA Homo sapiens
298 PPIE 10450
Affinity Capture-MS Homo sapiens
299 Ybx1 22608
Affinity Capture-MS Mus musculus
300 RPL10 6134
Affinity Capture-MS Homo sapiens
301 CCT4 10575
Co-fractionation Homo sapiens
302 CALM1 801
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
303 SNRPD2 6633
Co-fractionation Homo sapiens
304 TMPO 7112
Affinity Capture-MS Homo sapiens
305 ILF2 3608
Co-fractionation Homo sapiens
306 GSK3A 2931
Affinity Capture-MS Homo sapiens
307 TCEA1 6917
Affinity Capture-MS Homo sapiens
308 KIAA1429 25962
Affinity Capture-MS Homo sapiens
309 RPS20 6224
Co-fractionation Homo sapiens
310 PRDX3 10935
Co-fractionation Homo sapiens
311 TGFB1 7040
Affinity Capture-MS Homo sapiens
312 HSPA5 3309
Co-fractionation Homo sapiens
313 ATXN2L 11273
Co-fractionation Homo sapiens
314 COPS5 10987
Affinity Capture-MS Homo sapiens
315 SNRPC 6631
Affinity Capture-MS Homo sapiens
316 EED  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
317 MYCN  
Affinity Capture-MS Homo sapiens
318 CHD3 1107
Affinity Capture-Western Homo sapiens
319 IMPDH1 3614
Co-fractionation Homo sapiens
320 EDC4 23644
Co-fractionation Homo sapiens
321 POLD1 5424
Affinity Capture-MS Homo sapiens
322 RB1CC1 9821
Affinity Capture-MS Homo sapiens
323 ARMC8 25852
Affinity Capture-MS Homo sapiens
324 NONO 4841
Co-fractionation Homo sapiens
325 STAU1 6780
Affinity Capture-MS Homo sapiens
326 CCT5 22948
Co-fractionation Homo sapiens
327 UBE2I 7329
Biochemical Activity Homo sapiens
328 SMARCA4 6597
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
329 VCP 7415
Affinity Capture-MS Homo sapiens
330 DDX5 1655
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
331 SMAD3 4088
Reconstituted Complex Homo sapiens
332 DDX1 1653
Co-fractionation Homo sapiens
333 MBD3 53615
Affinity Capture-Western Homo sapiens
334 CDK9 1025
Affinity Capture-MS Homo sapiens
335 CEBPA  
Protein-peptide Homo sapiens
336 PRKACB 5567
Affinity Capture-MS Homo sapiens
337 DNAJB11 51726
Co-fractionation Homo sapiens
338 MAT2A 4144
Co-fractionation Homo sapiens
339 NUMA1 4926
Co-fractionation Homo sapiens
340 SFPQ 6421
Co-fractionation Homo sapiens
341 TAF15 8148
Co-fractionation Homo sapiens
342 NR4A1  
Affinity Capture-MS Homo sapiens
343 UPF1 5976
Co-fractionation Homo sapiens
344 DNAJC2 27000
Co-fractionation Homo sapiens
345 SNRPB 6628
Affinity Capture-MS Homo sapiens
346 RLIM 51132
Affinity Capture-MS Homo sapiens
347 SRSF1 6426
Co-fractionation Homo sapiens
348 ELAC2 60528
Co-fractionation Homo sapiens
349 SUZ12  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
350 SART1 9092
Co-fractionation Homo sapiens
351 NXF1 10482
Affinity Capture-RNA Homo sapiens
352 SF3A1 10291
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
353 AKAP8  
Two-hybrid Homo sapiens
Far Western Homo sapiens
354 IL7R  
Protein-RNA Homo sapiens
355 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
356 INO80B 83444
Affinity Capture-MS Homo sapiens
357 PRPSAP1 5635
Co-fractionation Homo sapiens
358 SF3B3 23450
Co-fractionation Homo sapiens
359 MDM2  
Affinity Capture-MS Homo sapiens
360 CCDC8  
Affinity Capture-MS Homo sapiens
361 BBLF2-BBLF3  
Two-hybrid
362 DHX15 1665
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
363 MAPKAPK2 9261
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
364 ARRB2 409
Affinity Capture-MS Homo sapiens
365 WDR4 10785
Co-fractionation Homo sapiens
366 SRRM1 10250
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
367 INPPL1 3636
Affinity Capture-MS Homo sapiens
368 WBP11  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
369 USP35  
Affinity Capture-MS Homo sapiens
370 CUL5 8065
Affinity Capture-MS Homo sapiens
371 DGCR8  
Affinity Capture-MS Homo sapiens
372 SMURF1 57154
Affinity Capture-MS Homo sapiens
373 ELAVL1 1994
Affinity Capture-MS Homo sapiens
374 HDAC1 3065
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
375 EIF4A3 9775
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
376 NUP35 129401
Proximity Label-MS Homo sapiens
377 GSTM3 2947
Co-fractionation Homo sapiens
378 RBFOX2 23543
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
379 RBM4 5936
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
380 ZNF217 7764
Affinity Capture-MS Homo sapiens
381 EZH2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
382 TRIP4 9325
Affinity Capture-MS Homo sapiens
383 AIRE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
384 TRIM31  
Affinity Capture-MS Homo sapiens
385 PINK1  
Affinity Capture-MS Homo sapiens
386 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
387 C9orf72  
Affinity Capture-MS Homo sapiens
388 DDX3X 1654
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
389 NEDD8 4738
Affinity Capture-MS Homo sapiens
390 CDC5L 988
Affinity Capture-MS Homo sapiens
391 NAE1 8883
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here