Gene description for SDHA
Gene name succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Gene symbol SDHA
Other names/aliases CMD1GG
FP
PGL5
SDH1
SDH2
SDHF
Species Homo sapiens
 Database cross references - SDHA
ExoCarta ExoCarta_6389
Vesiclepedia VP_6389
Entrez Gene 6389
HGNC 10680
MIM 600857
UniProt P31040  
 SDHA identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for SDHA
Molecular Function
    protein binding GO:0005515 IPI
    succinate dehydrogenase (quinone) activity GO:0008177 IBA
    succinate dehydrogenase (quinone) activity GO:0008177 IMP
    succinate dehydrogenase (quinone) activity GO:0008177 IMP
    electron transfer activity GO:0009055 IBA
    flavin adenine dinucleotide binding GO:0050660 IBA
Biological Process
    tricarboxylic acid cycle GO:0006099 IEA
    tricarboxylic acid cycle GO:0006099 NAS
    tricarboxylic acid cycle GO:0006099 TAS
    succinate metabolic process GO:0006105 IDA
    mitochondrial electron transport, succinate to ubiquinone GO:0006121 IBA
    mitochondrial electron transport, succinate to ubiquinone GO:0006121 NAS
    nervous system development GO:0007399 IMP
    respiratory electron transport chain GO:0022904 IDA
    proton motive force-driven mitochondrial ATP synthesis GO:0042776 NAS
Subcellular Localization
    nucleolus GO:0005730 IDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 ISS
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial matrix GO:0005759 TAS
    respiratory chain complex II (succinate dehydrogenase) GO:0045273 IBA
    respiratory chain complex II (succinate dehydrogenase) GO:0045273 IDA
    respiratory chain complex II (succinate dehydrogenase) GO:0045273 ISS
    respiratory chain complex II (succinate dehydrogenase) GO:0045273 TAS
 Experiment description of studies that identified SDHA in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
21
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
24
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
33
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for SDHA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 HIST1H2BC 8347
Affinity Capture-MS Homo sapiens
4 RIT1 6016
Negative Genetic Homo sapiens
5 MCM3 4172
Affinity Capture-MS Homo sapiens
6 SMC3 9126
Affinity Capture-MS Homo sapiens
7 TMEM14B  
Co-fractionation Homo sapiens
8 HDAC4  
Affinity Capture-MS Homo sapiens
9 PMPCA 23203
Proximity Label-MS Homo sapiens
10 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
11 CHCHD3 54927
Affinity Capture-MS Homo sapiens
12 MTCH1 23787
Co-fractionation Homo sapiens
13 IDH3A 3419
Affinity Capture-MS Homo sapiens
14 C6orf57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 ARHGAP39  
Affinity Capture-MS Homo sapiens
16 LDHB 3945
Affinity Capture-MS Homo sapiens
17 RPL30 6156
Affinity Capture-MS Homo sapiens
18 RIN3  
Affinity Capture-MS Homo sapiens
19 KCTD10 83892
Affinity Capture-MS Homo sapiens
20 ATP1B1 481
Co-fractionation Homo sapiens
21 ARL6IP5 10550
Affinity Capture-MS Homo sapiens
22 RPA2 6118
Proximity Label-MS Homo sapiens
23 KPNB1 3837
Affinity Capture-MS Homo sapiens
24 YWHAQ 10971
Affinity Capture-MS Homo sapiens
25 LDHA 3939
Affinity Capture-MS Homo sapiens
26 PRPH 5630
Affinity Capture-MS Homo sapiens
27 C9orf78 51759
Affinity Capture-MS Homo sapiens
28 UQCRB 7381
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
29 UBC 7316
Affinity Capture-MS Homo sapiens
30 ZC3H4 23211
Co-fractionation Homo sapiens
31 SYNE2 23224
Co-fractionation Homo sapiens
32 RPL12 6136
Affinity Capture-MS Homo sapiens
33 CAND1 55832
Affinity Capture-MS Homo sapiens
34 SDHC 6391
Co-fractionation Homo sapiens
35 SMPDL3B 27293
Affinity Capture-MS Homo sapiens
36 COPA 1314
Affinity Capture-MS Homo sapiens
37 UQCRFS1 7386
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
38 DNAJC15  
Proximity Label-MS Homo sapiens
39 NDUFS2 4720
Co-fractionation Homo sapiens
40 CCDC90B  
Proximity Label-MS Homo sapiens
41 OXCT1 5019
Co-fractionation Homo sapiens
42 SLC25A3 5250
Affinity Capture-MS Homo sapiens
43 GRB7 2886
Affinity Capture-MS Homo sapiens
44 KIAA1429 25962
Affinity Capture-MS Homo sapiens
45 CHCHD4  
Affinity Capture-MS Homo sapiens
46 HIST1H2BD 3017
Affinity Capture-MS Homo sapiens
47 PSMC5 5705
Affinity Capture-MS Homo sapiens
48 PPIA 5478
Affinity Capture-MS Homo sapiens
49 NDUFS3 4722
Co-fractionation Homo sapiens
50 TFAM 7019
Affinity Capture-MS Homo sapiens
51 KIF23 9493
Affinity Capture-MS Homo sapiens
52 SDHB 6390
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
53 COPS6 10980
Affinity Capture-MS Homo sapiens
54 CHCHD2  
Affinity Capture-MS Homo sapiens
55 HDLBP 3069
Affinity Capture-MS Homo sapiens
56 COPS5 10987
Affinity Capture-MS Homo sapiens
57 HINT2 84681
Proximity Label-MS Homo sapiens
58 MDH1 4190
Co-fractionation Homo sapiens
59 SLC27A2 11001
Co-fractionation Homo sapiens
60 YWHAG 7532
Affinity Capture-MS Homo sapiens
61 MDH2 4191
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
62 CPNE1 8904
Co-fractionation Homo sapiens
63 MCM6 4175
Affinity Capture-MS Homo sapiens
64 PROCR 10544
Co-fractionation Homo sapiens
65 PRDX3 10935
Affinity Capture-MS Homo sapiens
66 SURF1  
Proximity Label-MS Homo sapiens
67 RPN2 6185
Affinity Capture-MS Homo sapiens
68 EXD2  
Proximity Label-MS Homo sapiens
69 ITGA4 3676
Affinity Capture-MS Homo sapiens
70 PDIA6 10130
Affinity Capture-MS Homo sapiens
71 KIF2C 11004
Affinity Capture-MS Homo sapiens
72 NDUFV1 4723
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
73 ATG16L1 55054
Affinity Capture-MS Homo sapiens
74 PGAM1 5223
Affinity Capture-MS Homo sapiens
75 DHODH 1723
Co-fractionation Homo sapiens
76 ATP5H 10476
Affinity Capture-MS Homo sapiens
77 CCT7 10574
Affinity Capture-MS Homo sapiens
78 LDHAL6A  
Affinity Capture-MS Homo sapiens
79 CUL1 8454
Affinity Capture-MS Homo sapiens
80 TIMM50 92609
Co-fractionation Homo sapiens
81 MYCN  
Affinity Capture-MS Homo sapiens
82 WBP2 23558
Reconstituted Complex Homo sapiens
83 ASNS 440
Affinity Capture-MS Homo sapiens
84 CSNK2B 1460
Two-hybrid Homo sapiens
85 HK1 3098
Co-fractionation Homo sapiens
86 UQCRQ 27089
Co-fractionation Homo sapiens
87 MTERF3  
Co-fractionation Homo sapiens
88 KIF14 9928
Affinity Capture-MS Homo sapiens
89 POTEKP 440915
Affinity Capture-MS Homo sapiens
90 YWHAB 7529
Affinity Capture-MS Homo sapiens
91 PTPN3  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
92 PPIAL4A 653505
Affinity Capture-MS Homo sapiens
93 PCSK1  
Affinity Capture-MS Homo sapiens
94 BAG5 9529
Affinity Capture-MS Homo sapiens
95 FARSA 2193
Affinity Capture-MS Homo sapiens
96 PSMC2 5701
Affinity Capture-MS Homo sapiens
97 DLD 1738
Co-fractionation Homo sapiens
98 PAWR 5074
Affinity Capture-MS Homo sapiens
99 CYB5R3 1727
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
100 PSMD1 5707
Co-fractionation Homo sapiens
101 C6orf203  
Proximity Label-MS Homo sapiens
102 LMNA 4000
Affinity Capture-MS Homo sapiens
103 HIST1H2BG 8339
Affinity Capture-MS Homo sapiens
104 SAMM50 25813
Co-fractionation Homo sapiens
105 SUCLG1 8802
Co-fractionation Homo sapiens
106 CRY1  
Affinity Capture-MS Homo sapiens
107 RAB14 51552
Co-fractionation Homo sapiens
108 UBXN10  
Affinity Capture-MS Homo sapiens
109 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 SIRT3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 PDZRN3 23024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 RAB21 23011
Affinity Capture-MS Homo sapiens
113 HSP90B1 7184
Affinity Capture-MS Homo sapiens
114 APEX1 328
Affinity Capture-MS Homo sapiens
115 GDF15 9518
Affinity Capture-MS Homo sapiens
116 DARS 1615
Affinity Capture-MS Homo sapiens
117 NDFIP2 54602
Affinity Capture-MS Homo sapiens
118 EPRS 2058
Affinity Capture-MS Homo sapiens
119 HSCB 150274
Proximity Label-MS Homo sapiens
120 CHMP4B 128866
Affinity Capture-MS Homo sapiens
121 GRAMD4 23151
Affinity Capture-MS Homo sapiens
122 YWHAE 7531
Affinity Capture-MS Homo sapiens
123 NTRK1 4914
Affinity Capture-MS Homo sapiens
124 TPI1 7167
Affinity Capture-MS Homo sapiens
125 NDUFA2 4695
Co-fractionation Homo sapiens
126 BANF1 8815
Affinity Capture-MS Homo sapiens
127 CYC1 1537
Co-fractionation Homo sapiens
128 UQCRC1 7384
Affinity Capture-MS Homo sapiens
129 CRY2  
Affinity Capture-MS Homo sapiens
130 SERPINH1 871
Affinity Capture-MS Homo sapiens
131 DDX1 1653
Affinity Capture-MS Homo sapiens
132 LYRM4 57128
Co-fractionation Homo sapiens
133 HIST1H2BF 8343
Affinity Capture-MS Homo sapiens
134 CUL2 8453
Affinity Capture-MS Homo sapiens
135 MTRF1L  
Proximity Label-MS Homo sapiens
136 RAB10 10890
Affinity Capture-MS Homo sapiens
137 PSMD2 5708
Affinity Capture-MS Homo sapiens
138 RTP4  
Affinity Capture-MS Homo sapiens
139 TMEM70  
Proximity Label-MS Homo sapiens
140 ACN9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 PDSS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 SLC25A5 292
Affinity Capture-MS Homo sapiens
143 PMVK 10654
Affinity Capture-MS Homo sapiens
144 LRRC8A 56262
Co-fractionation Homo sapiens
145 MAT2A 4144
Affinity Capture-MS Homo sapiens
146 TPR 7175
Affinity Capture-MS Homo sapiens
147 HLA-B 3106
Affinity Capture-MS Homo sapiens
148 SDHAF1  
Affinity Capture-MS Homo sapiens
149 FGD5  
Affinity Capture-MS Homo sapiens
150 HIST1H2AD 3013
Affinity Capture-MS Homo sapiens
151 ACAT1 38
Co-fractionation Homo sapiens
152 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
153 GLOD4 51031
Co-fractionation Homo sapiens
154 TMED9 54732
Affinity Capture-MS Homo sapiens
155 ATP6V0D1 9114
Affinity Capture-MS Homo sapiens
156 ACLY 47
Co-fractionation Homo sapiens
157 ASS1 445
Affinity Capture-MS Homo sapiens
158 METTL14  
Affinity Capture-MS Homo sapiens
159 DGKG  
Affinity Capture-MS Homo sapiens
160 MTIF2 4528
Proximity Label-MS Homo sapiens
161 PSMC1 5700
Affinity Capture-MS Homo sapiens
162 YWHAZ 7534
Affinity Capture-MS Homo sapiens
163 LMNB1 4001
Affinity Capture-MS Homo sapiens
164 ATP1A1 476
Affinity Capture-MS Homo sapiens
165 HIGD1A 25994
Co-fractionation Homo sapiens
166 EIF2S1 1965
Affinity Capture-MS Homo sapiens
167 SIRT7  
Affinity Capture-MS Homo sapiens
168 HSPA4 3308
Affinity Capture-MS Homo sapiens
169 UQCRC2 7385
Affinity Capture-MS Homo sapiens
170 EEF2 1938
Affinity Capture-MS Homo sapiens
171 LMNB2 84823
Affinity Capture-MS Homo sapiens
172 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 ATP5F1 515
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
174 RMND1 55005
Proximity Label-MS Homo sapiens
175 PDIA3 2923
Affinity Capture-MS Homo sapiens
176 EGFR 1956
Negative Genetic Homo sapiens
177 HSD17B10 3028
Affinity Capture-MS Homo sapiens
178 FBXO6 26270
Affinity Capture-MS Homo sapiens
179 EIF4A1 1973
Co-fractionation Homo sapiens
180 EEF1B2 1933
Affinity Capture-MS Homo sapiens
181 FN1 2335
Affinity Capture-MS Homo sapiens
182 NXF1 10482
Affinity Capture-RNA Homo sapiens
183 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
184 TOMM70A 9868
Co-fractionation Homo sapiens
185 AURKB 9212
Affinity Capture-MS Homo sapiens
186 MRPL1  
Co-fractionation Homo sapiens
187 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
188 BIRC6 57448
Affinity Capture-MS Homo sapiens
189 GCN1L1 10985
Co-fractionation Homo sapiens
190 DUSP4 1846
Affinity Capture-MS Homo sapiens
191 CPNE3 8895
Co-fractionation Homo sapiens
192 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
193 EPHA2 1969
Proximity Label-MS Homo sapiens
194 MYC  
Affinity Capture-MS Homo sapiens
195 RPA3 6119
Proximity Label-MS Homo sapiens
196 RUVBL2 10856
Affinity Capture-MS Homo sapiens
197 EMC2 9694
Affinity Capture-MS Homo sapiens
198 SLC2A14 144195
Co-fractionation Homo sapiens
199 CCT8 10694
Affinity Capture-MS Homo sapiens
200 EEF1G 1937
Affinity Capture-MS Homo sapiens
201 CCT2 10576
Affinity Capture-MS Homo sapiens
202 IMPAD1 54928
Co-fractionation Homo sapiens
203 HSPB2  
Two-hybrid Homo sapiens
204 ACAD9 28976
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
205 DUSP9  
Affinity Capture-MS Homo sapiens
206 RPN1 6184
Affinity Capture-MS Homo sapiens
207 GANAB 23193
Affinity Capture-MS Homo sapiens
208 PDSS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 HSPD1 3329
Co-fractionation Homo sapiens
210 HSPA9 3313
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
211 NDUFV2 4729
Co-fractionation Homo sapiens
212 PDP1 54704
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 RPL26 6154
Affinity Capture-MS Homo sapiens
214 NFATC2  
Affinity Capture-MS Homo sapiens
215 MARC1  
Co-fractionation Homo sapiens
216 HIST1H2BI 8346
Affinity Capture-MS Homo sapiens
217 TAP1 6890
Co-fractionation Homo sapiens
218 MCUR1 63933
Proximity Label-MS Homo sapiens
219 DNAJC6  
Affinity Capture-MS Homo sapiens
220 CPT1A 1374
Affinity Capture-MS Homo sapiens
221 DSP 1832
Affinity Capture-MS Homo sapiens
222 SDHAF2 54949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 MIB1 57534
Affinity Capture-MS Homo sapiens
224 CLPP 8192
Proximity Label-MS Homo sapiens
225 APOA1BP 128240
Co-fractionation Homo sapiens
226 CS 1431
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
227 ARRB2 409
Affinity Capture-MS Homo sapiens
228 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
229 FASN 2194
Affinity Capture-MS Homo sapiens
230 TMED10 10972
Affinity Capture-MS Homo sapiens
231 NEDD8 4738
Affinity Capture-MS Homo sapiens
232 AUH 549
Proximity Label-MS Homo sapiens
233 CKAP4 10970
Affinity Capture-MS Homo sapiens
234 JUP 3728
Affinity Capture-MS Homo sapiens
235 FBXL6  
Affinity Capture-MS Homo sapiens
236 TP53 7157
Affinity Capture-MS Homo sapiens
237 ICT1 3396
Affinity Capture-MS Homo sapiens
238 XRCC6 2547
Co-fractionation Homo sapiens
239 SUCLG2 8801
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
240 MCM5 4174
Affinity Capture-MS Homo sapiens
241 HSD17B4 3295
Affinity Capture-MS Homo sapiens
242 CKB 1152
Affinity Capture-MS Homo sapiens
243 CUL5 8065
Affinity Capture-MS Homo sapiens
244 PDHA1 5160
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
245 DNAJA3 9093
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
246 HLA-A 3105
Affinity Capture-MS Homo sapiens
247 SQSTM1 8878
Co-fractionation Homo sapiens
248 HSPB1 3315
Co-fractionation Homo sapiens
249 ELAVL1 1994
Affinity Capture-MS Homo sapiens
250 COX8A  
Proximity Label-MS Homo sapiens
251 TKT 7086
Affinity Capture-MS Homo sapiens
252 OTUB1 55611
Affinity Capture-MS Homo sapiens
253 EIF4A3 9775
Affinity Capture-MS Homo sapiens
254 C21orf33  
Proximity Label-MS Homo sapiens
255 MYL12A 10627
Affinity Capture-MS Homo sapiens
256 CDK1 983
Affinity Capture-MS Homo sapiens
257 SSBP1 6742
Proximity Label-MS Homo sapiens
258 SHMT2 6472
Affinity Capture-MS Homo sapiens
259 RAVER1 125950
Co-fractionation Homo sapiens
260 SFXN1 94081
Affinity Capture-MS Homo sapiens
261 UFL1 23376
Affinity Capture-MS Homo sapiens
262 NAMPT 10135
Affinity Capture-MS Homo sapiens
263 DNAJB11 51726
Affinity Capture-MS Homo sapiens
264 NDUFS8 4728
Co-fractionation Homo sapiens
265 TBRG4 9238
Proximity Label-MS Homo sapiens
266 CANX 821
Affinity Capture-MS Homo sapiens
267 AARS2  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
268 HNRNPH3 3189
Affinity Capture-MS Homo sapiens
269 C16orf72 29035
Affinity Capture-MS Homo sapiens
270 PINK1  
Affinity Capture-MS Homo sapiens
271 TMEM109 79073
Affinity Capture-MS Homo sapiens
272 ANXA5 308
Affinity Capture-MS Homo sapiens
273 CIT 11113
Affinity Capture-MS Homo sapiens
274 FLOT1 10211
Affinity Capture-MS Homo sapiens
275 C1QBP 708
Proximity Label-MS Homo sapiens
276 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
277 ATP6V0A2 23545
Affinity Capture-MS Homo sapiens
278 PEX5 5830
Affinity Capture-MS Homo sapiens
279 KRAS 3845
Negative Genetic Homo sapiens
280 C9orf72  
Affinity Capture-MS Homo sapiens
281 PGAM2 5224
Affinity Capture-MS Homo sapiens
282 METTL17  
Proximity Label-MS Homo sapiens
283 ATXN3 4287
Affinity Capture-MS Homo sapiens
284 SSRP1 6749
Affinity Capture-MS Homo sapiens
285 SUCLA2 8803
Co-fractionation Homo sapiens
286 HMGB3 3149
Affinity Capture-MS Homo sapiens
287 NDUFS6  
Co-fractionation Homo sapiens
288 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
289 MRPS9 64965
Co-fractionation Homo sapiens
290 CUL4A 8451
Affinity Capture-MS Homo sapiens
291 MAP4K1  
Affinity Capture-MS Homo sapiens
292 PPIB 5479
Co-fractionation Homo sapiens
293 DNAJC22  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here