Gene description for LARP1
Gene name La ribonucleoprotein domain family, member 1
Gene symbol LARP1
Other names/aliases LARP
Species Homo sapiens
 Database cross references - LARP1
ExoCarta ExoCarta_23367
Vesiclepedia VP_23367
Entrez Gene 23367
HGNC 29531
MIM 612059
UniProt Q6PKG0  
 LARP1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for LARP1
Molecular Function
    RNA cap binding GO:0000339 IDA
    RNA 7-methylguanosine cap binding GO:0000340 IDA
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    mRNA 3'-UTR binding GO:0003730 IDA
    protein binding GO:0005515 IPI
    eukaryotic initiation factor 4E binding GO:0008190 IPI
    translation activator activity GO:0008494 IMP
    translation initiation factor binding GO:0031369 IDA
    ribosomal small subunit binding GO:0043024 IDA
    cadherin binding GO:0045296 HDA
    mRNA 5'-UTR binding GO:0048027 IDA
    mRNA 5'-UTR binding GO:0048027 IMP
Biological Process
    translational initiation GO:0006413 IMP
    cell population proliferation GO:0008283 IMP
    post-transcriptional regulation of gene expression GO:0010608 IDA
    positive regulation of macroautophagy GO:0016239 IMP
    negative regulation of translation GO:0017148 IMP
    TOR signaling GO:0031929 IMP
    TORC1 signaling GO:0038202 IMP
    positive regulation of viral genome replication GO:0045070 IMP
    positive regulation of translation GO:0045727 IBA
    negative regulation of translational initiation GO:0045947 IMP
    positive regulation of translational initiation GO:0045948 IMP
    mRNA stabilization GO:0048255 IMP
    cellular response to rapamycin GO:0072752 IMP
    response to amino acid starvation GO:1990928 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 TAS
    cytoplasmic stress granule GO:0010494 IBA
    cytoplasmic stress granule GO:0010494 IDA
    membrane GO:0016020 HDA
    TORC1 complex GO:0031931 IDA
 Experiment description of studies that identified LARP1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
29
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for LARP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDCA5  
Co-fractionation Homo sapiens
2 EIF3A 8661
Co-fractionation Homo sapiens
3 DGCR8  
Affinity Capture-MS Homo sapiens
4 RPSAP58 388524
Affinity Capture-MS Homo sapiens
5 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
6 HNRNPC 3183
Affinity Capture-MS Homo sapiens
7 H1FNT  
Affinity Capture-MS Homo sapiens
8 PABPC1 26986
Co-fractionation Homo sapiens
9 NUPL2 11097
Affinity Capture-MS Homo sapiens
10 PAXIP1  
Affinity Capture-MS Homo sapiens
11 RPS3A 6189
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
12 NCAPH 23397
Affinity Capture-MS Homo sapiens
13 ANLN 54443
Affinity Capture-MS Homo sapiens
14 EIF3C 8663
Co-fractionation Homo sapiens
15 EIF3K 27335
Co-fractionation Homo sapiens
16 MTOR 2475
Co-fractionation Homo sapiens
17 PSMD11 5717
Co-fractionation Homo sapiens
18 TARDBP 23435
Affinity Capture-MS Homo sapiens
19 YWHAE 7531
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 FGFBP1 9982
Affinity Capture-MS Homo sapiens
21 Ybx1 22608
Affinity Capture-MS Mus musculus
22 LARP1B 55132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
23 NOP56 10528
Affinity Capture-MS Homo sapiens
24 CAT 847
Cross-Linking-MS (XL-MS) Homo sapiens
25 TSG101 7251
Affinity Capture-MS Homo sapiens
26 RPL10 6134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 KIF20A 10112
Affinity Capture-MS Homo sapiens
28 SRGAP2 23380
Affinity Capture-MS Homo sapiens
29 CSNK2A1 1457
Biochemical Activity Homo sapiens
30 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
31 CAND1 55832
Affinity Capture-MS Homo sapiens
32 PSMD10 5716
Co-fractionation Homo sapiens
33 NLRP2  
Co-fractionation Homo sapiens
34 KLF4  
Affinity Capture-MS Homo sapiens
35 Ywhaz 22631
Two-hybrid Mus musculus
36 EIF4E2  
Affinity Capture-MS Homo sapiens
37 TACC2 10579
Co-fractionation Homo sapiens
38 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
39 RPS3 6188
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
40 ILF2 3608
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
42 LRPPRC 10128
Co-fractionation Homo sapiens
43 RPS18 6222
Co-fractionation Homo sapiens
44 SURF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 CAPZB 832
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
46 RPS6 6194
Affinity Capture-MS Homo sapiens
47 RPS20 6224
Proximity Label-MS Homo sapiens
48 SART3 9733
Affinity Capture-MS Homo sapiens
49 GSPT2 23708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 RDX 5962
Co-fractionation Homo sapiens
51 PRR11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
53 IMPDH2 3615
Co-fractionation Homo sapiens
54 SRP19 6728
Affinity Capture-MS Homo sapiens
55 KIF23 9493
Affinity Capture-MS Homo sapiens
56 USP10 9100
Affinity Capture-MS Homo sapiens
57 ZNF638 27332
Affinity Capture-MS Homo sapiens
58 KIF5B 3799
Co-fractionation Homo sapiens
59 MAGI1  
Affinity Capture-MS Homo sapiens
60 COPS5 10987
Affinity Capture-MS Homo sapiens
61 FBXW7  
Affinity Capture-MS Homo sapiens
62 PRC1 9055
Affinity Capture-MS Homo sapiens
63 BHLHA15  
Affinity Capture-MS Homo sapiens
64 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 SNRPC 6631
Affinity Capture-MS Homo sapiens
66 FBL 2091
Proximity Label-MS Homo sapiens
67 YWHAG 7532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 KLF15  
Affinity Capture-MS Homo sapiens
69 RPS9 6203
Co-fractionation Homo sapiens
70 GSPT1 2935
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
71 SRSF3 6428
Affinity Capture-MS Homo sapiens
72 EIF3E 3646
Co-fractionation Homo sapiens
73 DCLK1 9201
Affinity Capture-MS Homo sapiens
74 TESK2  
Affinity Capture-MS Homo sapiens
75 ITGA4 3676
Affinity Capture-MS Homo sapiens
76 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
77 SRP68 6730
Affinity Capture-MS Homo sapiens
78 ABT1 29777
Affinity Capture-MS Homo sapiens
79 YWHAH 7533
Affinity Capture-MS Homo sapiens
80 ATG16L1 55054
Affinity Capture-MS Homo sapiens
81 DDX6 1656
Affinity Capture-MS Homo sapiens
82 SFN 2810
Co-fractionation Homo sapiens
83 LRFN1  
Affinity Capture-MS Homo sapiens
84 KSR1  
Affinity Capture-MS Homo sapiens
85 TGM2 7052
Co-fractionation Homo sapiens
86 CALR 811
Co-fractionation Homo sapiens
87 Eif3a 13669
Affinity Capture-MS Mus musculus
88 CUL1 8454
Affinity Capture-MS Homo sapiens
89 MYCN  
Affinity Capture-MS Homo sapiens
90 RBM42  
Affinity Capture-MS Homo sapiens
91 OASL 8638
Affinity Capture-MS Homo sapiens
92 RPS11 6205
Affinity Capture-MS Homo sapiens
93 PABPC4 8761
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 FAM120A 23196
Affinity Capture-MS Homo sapiens
95 RPS2 6187
Affinity Capture-MS Homo sapiens
96 KIF14 9928
Affinity Capture-MS Homo sapiens
97 LARP4B 23185
Affinity Capture-MS Homo sapiens
98 HSPA8 3312
Affinity Capture-MS Homo sapiens
99 LIN28A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 YWHAB 7529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
101 CPEB1  
Affinity Capture-MS Homo sapiens
102 KLF16  
Affinity Capture-MS Homo sapiens
103 CHMP4C 92421
Affinity Capture-MS Homo sapiens
104 AURKA 6790
Affinity Capture-MS Homo sapiens
105 KLF5  
Affinity Capture-MS Homo sapiens
106 SRP9 6726
Affinity Capture-MS Homo sapiens
107 DLD 1738
Affinity Capture-MS Homo sapiens
108 SLC25A10 1468
Co-fractionation Homo sapiens
109 WASL 8976
Co-fractionation Homo sapiens
110 CNOT2  
Affinity Capture-MS Homo sapiens
111 LIN28B  
Affinity Capture-MS Homo sapiens
112 ZNF346  
Affinity Capture-MS Homo sapiens
113 RBM47 54502
Affinity Capture-MS Homo sapiens
114 CUL4B 8450
Affinity Capture-MS Homo sapiens
115 PARK2  
Affinity Capture-MS Homo sapiens
116 RPS10 6204
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
117 SIPA1L1 26037
Affinity Capture-MS Homo sapiens
118 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 YBX2 51087
Affinity Capture-MS Homo sapiens
120 GLE1 2733
Affinity Capture-MS Homo sapiens
121 MAPRE1 22919
Affinity Capture-MS Homo sapiens
122 PSMD14 10213
Co-fractionation Homo sapiens
123 SRSF6 6431
Affinity Capture-MS Homo sapiens
124 PURG  
Affinity Capture-MS Homo sapiens
125 DDX21 9188
Affinity Capture-MS Homo sapiens
126 Pabpc1 18458
Affinity Capture-MS Mus musculus
127 RPL5 6125
Affinity Capture-MS Homo sapiens
128 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
129 RPL35 11224
Affinity Capture-MS Homo sapiens
130 RB1CC1 9821
Affinity Capture-MS Homo sapiens
131 Srp72  
Affinity Capture-MS Mus musculus
132 FOXL2  
Affinity Capture-MS Homo sapiens
133 CSNK1A1 1452
Affinity Capture-MS Homo sapiens
134 BARD1 580
Affinity Capture-MS Homo sapiens
135 NTRK1 4914
Affinity Capture-MS Homo sapiens
136 FGF8  
Affinity Capture-MS Homo sapiens
137 VIM 7431
Co-fractionation Homo sapiens
138 IFI16 3428
Affinity Capture-MS Homo sapiens
139 U2AF2 11338
Affinity Capture-MS Homo sapiens
140 REXO4  
Affinity Capture-MS Homo sapiens
141 CDH1 999
Proximity Label-MS Homo sapiens
142 LUC7L2 51631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
143 YWHAQ 10971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
144 RPA4  
Proximity Label-MS Homo sapiens
145 BCL2L1 598
Two-hybrid Homo sapiens
146 CTPS1 1503
Co-fractionation Homo sapiens
147 Rrbp1  
Affinity Capture-MS Mus musculus
148 MAP4 4134
Co-fractionation Homo sapiens
149 CUL2 8453
Affinity Capture-MS Homo sapiens
150 RRP1B 23076
Affinity Capture-MS Homo sapiens
151 KCTD3  
Affinity Capture-MS Homo sapiens
152 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
153 Ksr1  
Affinity Capture-MS Mus musculus
154 FGF13  
Affinity Capture-MS Homo sapiens
155 ARRDC3 57561
Affinity Capture-MS Homo sapiens
156 SRPK1 6732
Biochemical Activity Homo sapiens
157 NFX1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
158 TRIM16 10626
Co-fractionation Homo sapiens
159 RPL11 6135
Affinity Capture-MS Homo sapiens
160 RPLP0 6175
Affinity Capture-MS Homo sapiens
161 ELAVL2 1993
Affinity Capture-MS Homo sapiens
162 METAP2 10988
Affinity Capture-MS Homo sapiens
163 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 PAIP2B  
Affinity Capture-MS Homo sapiens
165 HNRNPD 3184
Affinity Capture-MS Homo sapiens
166 ACTN1 87
Co-fractionation Homo sapiens
167 EIF4B 1975
Co-fractionation Homo sapiens
168 RBM39 9584
Affinity Capture-MS Homo sapiens
169 RPS19 6223
Affinity Capture-MS Homo sapiens
170 RPL31 6160
Affinity Capture-MS Homo sapiens
171 UBE2H 7328
Affinity Capture-MS Homo sapiens
172 FOXG1  
Affinity Capture-MS Homo sapiens
173 TRIM31  
Affinity Capture-MS Homo sapiens
174 CLK3  
Affinity Capture-MS Homo sapiens
175 Rbm47  
Two-hybrid Mus musculus
176 RC3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 ECT2 1894
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 DHX15 1665
Co-fractionation Homo sapiens
179 SIRT7  
Affinity Capture-MS Homo sapiens
180 SRSF4 6429
Affinity Capture-MS Homo sapiens
181 SRSF1 6426
Affinity Capture-MS Homo sapiens
182 MEX3A  
Affinity Capture-RNA Homo sapiens
183 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 CTCF  
Affinity Capture-MS Homo sapiens
185 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 YWHAZ 7534
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
187 SRSF5 6430
Affinity Capture-MS Homo sapiens
188 SSB 6741
Affinity Capture-MS Homo sapiens
189 NUP43 348995
Proximity Label-MS Homo sapiens
190 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 FUS 2521
Affinity Capture-MS Homo sapiens
192 MYC  
Affinity Capture-MS Homo sapiens
193 SUZ12  
Affinity Capture-MS Homo sapiens
194 PHLPP1  
Proximity Label-MS Homo sapiens
195 AURKB 9212
Affinity Capture-MS Homo sapiens
196 PRR3  
Affinity Capture-MS Homo sapiens
197 PIP4K2A 5305
Co-fractionation Homo sapiens
198 MKRN2 23609
Affinity Capture-MS Homo sapiens
199 CBX6  
Affinity Capture-MS Homo sapiens
200 RBM4B  
Affinity Capture-MS Homo sapiens
201 CBY1  
Affinity Capture-MS Homo sapiens
202 PSPC1 55269
Affinity Capture-MS Homo sapiens
203 RPA3 6119
Proximity Label-MS Homo sapiens
204 RPS13 6207
Co-fractionation Homo sapiens
205 THAP3  
Affinity Capture-MS Homo sapiens
206 GIGYF1  
Affinity Capture-MS Homo sapiens
207 NOL12 79159
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 PABPC5 140886
Affinity Capture-MS Homo sapiens
209 RPS14 6208
Co-fractionation Homo sapiens
210 TOP1 7150
Affinity Capture-MS Homo sapiens
211 NFKB1 4790
Co-fractionation Homo sapiens
212 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 CGN  
Affinity Capture-MS Homo sapiens
214 PPP2R1A 5518
Co-fractionation Homo sapiens
215 DDRGK1 65992
Affinity Capture-MS Homo sapiens
216 RNF2  
Affinity Capture-MS Homo sapiens
217 FOXQ1  
Affinity Capture-MS Homo sapiens
218 Rpl35 66489
Affinity Capture-MS Mus musculus
219 CEBPA  
Protein-peptide Homo sapiens
220 CCDC155  
Two-hybrid Homo sapiens
221 EDEM1  
Affinity Capture-MS Homo sapiens
222 RPL26 6154
Affinity Capture-MS Homo sapiens
223 ZC3H3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
224 C9orf72  
Affinity Capture-MS Homo sapiens
225 RBMS2 5939
Affinity Capture-MS Homo sapiens
226 RPS16 6217
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
227 TNNT1  
Two-hybrid Homo sapiens
228 WDR77 79084
Affinity Capture-MS Homo sapiens
229 G3BP2 9908
Affinity Capture-MS Homo sapiens
230 HECTD1 25831
Affinity Capture-MS Homo sapiens
231 YBX1 4904
Affinity Capture-MS Homo sapiens
232 GRK5 2869
Affinity Capture-MS Homo sapiens
233 KIF13B 23303
Affinity Capture-MS Homo sapiens
234 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
235 MKRN1 23608
Affinity Capture-MS Homo sapiens
236 HOXA2  
Affinity Capture-MS Homo sapiens
237 SIRT6  
Affinity Capture-MS Homo sapiens
238 ILF3 3609
Affinity Capture-MS Homo sapiens
239 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
240 RPL6 6128
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
241 CIT 11113
Affinity Capture-MS Homo sapiens
242 RTKN 6242
Affinity Capture-MS Homo sapiens
243 RNH1 6050
Co-fractionation Homo sapiens
244 DENND1A 57706
Affinity Capture-MS Homo sapiens
245 APOBEC3D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
246 PPM1H  
Affinity Capture-MS Homo sapiens
247 MCM5 4174
Co-fractionation Homo sapiens
248 ZCRB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 CUL5 8065
Affinity Capture-MS Homo sapiens
250 RPS12 6206
Co-fractionation Homo sapiens
251 PRKACA 5566
Affinity Capture-MS Homo sapiens
252 RPS4X 6191
Co-fractionation Homo sapiens
253 MAGEL2  
Proximity Label-MS Homo sapiens
254 MKRN3  
Affinity Capture-MS Homo sapiens
255 PRMT1 3276
Affinity Capture-MS Homo sapiens
256 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
257 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
258 IPO5 3843
Co-fractionation Homo sapiens
259 STRBP 55342
Affinity Capture-MS Homo sapiens
260 ZBTB21  
Affinity Capture-MS Homo sapiens
261 RBMX 27316
Co-fractionation Homo sapiens
262 RPS5 6193
Co-fractionation Homo sapiens
263 NIFK 84365
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 MNDA 4332
Affinity Capture-MS Homo sapiens
265 KLF8  
Affinity Capture-MS Homo sapiens
266 ESR1  
Affinity Capture-MS Homo sapiens
267 DRG1 4733
Affinity Capture-MS Homo sapiens
268 UFL1 23376
Affinity Capture-MS Homo sapiens
269 KRR1 11103
Affinity Capture-MS Homo sapiens
270 MCM3 4172
Co-fractionation Homo sapiens
271 NEIL1  
Affinity Capture-MS Homo sapiens
272 SNIP1  
Affinity Capture-MS Homo sapiens
273 LIMA1 51474
Affinity Capture-MS Homo sapiens
274 EZH2  
Affinity Capture-MS Homo sapiens
275 IL17B 27190
Affinity Capture-MS Homo sapiens
276 RPSA 3921
Affinity Capture-MS Homo sapiens
277 SNRNP70 6625
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 PLS3 5358
Co-fractionation Homo sapiens
279 SRSF7 6432
Affinity Capture-MS Homo sapiens
280 PINK1  
Affinity Capture-MS Homo sapiens
281 Dusp14  
Two-hybrid Mus musculus
282 RBM8A 9939
Affinity Capture-MS Homo sapiens
283 RPS8 6202
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
284 EIF2S3 1968
Affinity Capture-MS Homo sapiens
285 SERBP1 26135
Proximity Label-MS Homo sapiens
286 PPAN 56342
Affinity Capture-MS Homo sapiens
287 RPS29 6235
Co-fractionation Homo sapiens
288 HNRNPU 3192
Affinity Capture-MS Homo sapiens
289 GNB2L1 10399
Affinity Capture-MS Homo sapiens
290 AR 367
Affinity Capture-MS Homo sapiens
291 RPL36AL 6166
Affinity Capture-MS Homo sapiens
292 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
293 MAST3  
Affinity Capture-MS Homo sapiens
294 IVNS1ABP  
Affinity Capture-MS Homo sapiens
295 PAIP1 10605
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
296 LUC7L 55692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
297 SH3PXD2A 9644
Affinity Capture-MS Homo sapiens
298 SRP72 6731
Affinity Capture-MS Homo sapiens
299 BTF3 689
Affinity Capture-MS Homo sapiens
300 RPL17 6139
Affinity Capture-MS Homo sapiens
301 EP300 2033
Affinity Capture-MS Homo sapiens
302 EIF3L 51386
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here