Gene description for TEX10
Gene name testis expressed 10
Gene symbol TEX10
Other names/aliases Ipi1
bA208F1.2
Species Homo sapiens
 Database cross references - TEX10
ExoCarta ExoCarta_54881
Vesiclepedia VP_54881
Entrez Gene 54881
HGNC 25988
UniProt Q9NXF1  
 TEX10 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for TEX10
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IEA
    mitochondrion GO:0005739 IDA
    MLL1 complex GO:0071339 IBA
    MLL1 complex GO:0071339 IDA
 Experiment description of studies that identified TEX10 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TEX10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDC14B 8555
Proximity Label-MS Homo sapiens
2 ZNF668  
Affinity Capture-MS Homo sapiens
3 PCED1A  
Affinity Capture-MS Homo sapiens
4 SENP3 26168
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
5 H1FNT  
Affinity Capture-MS Homo sapiens
6 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
7 C2CD4A  
Affinity Capture-MS Homo sapiens
8 COIL  
Proximity Label-MS Homo sapiens
9 KPNA1 3836
Affinity Capture-MS Homo sapiens
10 RIT1 6016
Negative Genetic Homo sapiens
11 RPA2 6118
Affinity Capture-MS Homo sapiens
12 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
13 NOP56 10528
Proximity Label-MS Homo sapiens
14 RPL10 6134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 RPL15 6138
Affinity Capture-MS Homo sapiens
16 HIST3H2BB 128312
Affinity Capture-MS Homo sapiens
17 RSBN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CENPA  
Proximity Label-MS Homo sapiens
19 APEX1 328
Proximity Label-MS Homo sapiens
20 DDX23 9416
Proximity Label-MS Homo sapiens
21 RPL4 6124
Affinity Capture-MS Homo sapiens
22 PTPN12 5782
Two-hybrid Homo sapiens
23 MDN1 23195
Co-fractionation Homo sapiens
24 H2AFB3  
Affinity Capture-MS Homo sapiens
25 Htatsf1  
Two-hybrid Mus musculus
26 FBXW7  
Affinity Capture-MS Homo sapiens
27 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 POLR1E  
Proximity Label-MS Homo sapiens
29 DUSP5  
Proximity Label-MS Homo sapiens
30 OBSL1 23363
Affinity Capture-MS Homo sapiens
31 SRP14 6727
Affinity Capture-MS Homo sapiens
32 BRD4 23476
Affinity Capture-MS Homo sapiens
33 TNFRSF13B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 Eif3i 54709
Affinity Capture-MS Mus musculus
35 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 H2AFY2 55506
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 MYCN  
Affinity Capture-MS Homo sapiens
38 RBM42  
Affinity Capture-MS Homo sapiens
39 ASF1A 25842
Proximity Label-MS Homo sapiens
40 TNFRSF1B  
Affinity Capture-MS Homo sapiens
41 RBM8A 9939
Affinity Capture-MS Homo sapiens
42 DMRTB1  
Two-hybrid Homo sapiens
43 UFL1 23376
Affinity Capture-MS Homo sapiens
44 P4HA1 5033
Affinity Capture-MS Homo sapiens
45 PARK2  
Affinity Capture-MS Homo sapiens
46 DRG1 4733
Affinity Capture-MS Homo sapiens
47 PHF14 9678
Cross-Linking-MS (XL-MS) Homo sapiens
48 Nudt21 68219
Two-hybrid Mus musculus
49 MAPRE1 22919
Affinity Capture-MS Homo sapiens
50 ZBTB48  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
52 RPL18A 6142
Affinity Capture-MS Homo sapiens
53 LHX1  
Proximity Label-MS Homo sapiens
54 Srp72  
Affinity Capture-MS Mus musculus
55 NTRK1 4914
Affinity Capture-MS Homo sapiens
56 RPL31 6160
Proximity Label-MS Homo sapiens
57 LAS1L 81887
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
58 IFI16 3428
Affinity Capture-MS Homo sapiens
59 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 SUMO2 6613
Reconstituted Complex Homo sapiens
61 PRDM16 63976
Two-hybrid Homo sapiens
62 RPL36 25873
Affinity Capture-MS Homo sapiens
63 PML 5371
Affinity Capture-MS Homo sapiens
64 HECTD1 25831
Affinity Capture-MS Homo sapiens
65 RPLP0 6175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 PELP1 27043
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 MAGEB2 4113
Affinity Capture-MS Homo sapiens
68 C3orf49  
Affinity Capture-MS Homo sapiens
69 HIST1H2AB 8335
Affinity Capture-MS Homo sapiens
70 KIF2C 11004
Affinity Capture-MS Homo sapiens
71 CD3EAP  
Proximity Label-MS Homo sapiens
72 FGFBP1 9982
Affinity Capture-MS Homo sapiens
73 SLX4  
Affinity Capture-MS Homo sapiens
74 ZBTB2 57621
Affinity Capture-MS Homo sapiens
75 RASGEF1A  
Affinity Capture-MS Homo sapiens
76 USP42  
Affinity Capture-MS Homo sapiens
77 FANCD2  
Affinity Capture-MS Homo sapiens
78 ABT1 29777
Affinity Capture-MS Homo sapiens
79 RPS2 6187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 C9orf78 51759
Affinity Capture-MS Homo sapiens
81 SIRT7  
Affinity Capture-MS Homo sapiens
82 NPM3 10360
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 WDR55  
Affinity Capture-MS Homo sapiens
84 RPL3 6122
Affinity Capture-MS Homo sapiens
85 IPO5 3843
Affinity Capture-MS Homo sapiens
86 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
87 AURKB 9212
Affinity Capture-MS Homo sapiens
88 CBX6  
Affinity Capture-MS Homo sapiens
89 CHCHD2  
Affinity Capture-MS Homo sapiens
90 MYC  
Affinity Capture-MS Homo sapiens
91 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
92 H2AFB1  
Affinity Capture-MS Homo sapiens
93 DDRGK1 65992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 RNF2  
Affinity Capture-MS Homo sapiens
95 FOXQ1  
Affinity Capture-MS Homo sapiens
96 H2AFB2  
Affinity Capture-MS Homo sapiens
97 FSCN1 6624
Affinity Capture-MS Homo sapiens
98 NEUROG3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 PYHIN1  
Affinity Capture-MS Homo sapiens
100 GNL3 26354
Co-fractionation Homo sapiens
101 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
103 SIRT6  
Affinity Capture-MS Homo sapiens
104 PARP1 142
Proximity Label-MS Homo sapiens
105 PDGFB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 MNDA 4332
Affinity Capture-MS Homo sapiens
107 Eif3g 53356
Two-hybrid Mus musculus
108 USP36  
Affinity Capture-MS Homo sapiens
109 RPA1 6117
Affinity Capture-MS Homo sapiens
110 SRP19 6728
Affinity Capture-MS Homo sapiens
111 PHF19  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 SRP72 6731
Affinity Capture-MS Homo sapiens
113 COX8A  
Proximity Label-MS Homo sapiens
114 Cbx1  
Affinity Capture-MS Mus musculus
115 PKP1 5317
Affinity Capture-MS Homo sapiens
116 NIFK 84365
Proximity Label-MS Homo sapiens
117 WDR18 57418
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 DHX40  
Proximity Label-MS Homo sapiens
119 RBM4 5936
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 NEIL1  
Affinity Capture-MS Homo sapiens
121 RPS24 6229
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 RPS6 6194
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
123 CUL7 9820
Affinity Capture-MS Homo sapiens
124 KRAS 3845
Synthetic Lethality Homo sapiens
125 GNB2L1 10399
Affinity Capture-MS Homo sapiens
126 SP7  
Proximity Label-MS Homo sapiens
127 ZNF467  
Affinity Capture-MS Homo sapiens
128 NOL9 79707
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
129 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
130 CUL4A 8451
Affinity Capture-MS Homo sapiens
131 HIST1H2BA 255626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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