Experiment description of studies that identified H3F3C in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM Biophysical techniques ✔ Alix|TSG101|CD63|CD81 Enriched markers ✔ GOLGA2 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

2 Experiment ID 138 MISEV standards ✔ EM Biophysical techniques ✔ HSP70|HSP90|RAB5|LAMP2|CD9 Enriched markers ✔ HSP90B1 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry [QTOF]    PubMed ID 22723089     Organism Homo sapiens Experiment description Prostate cancer cell derived exosomes Authors "Hosseini-Beheshti E, Guns ES." Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name DU145 - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF]

3 Experiment ID 143 MISEV standards ✔ EM Biophysical techniques ✔ HSP70|HSP90|RAB5|LAMP2|CD9 Enriched markers ✔ HSP90B1 Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry [QTOF]    PubMed ID 22723089     Organism Homo sapiens Experiment description Prostate cancer cell derived exosomes Authors "Hosseini-Beheshti E, Guns ES." Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name LNCaP - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF]

Protein-protein interactions for H3F3C

Protein Interactor ExoCarta ID Identification method PubMed Species 1 FAN1   Affinity Capture-MS Homo sapiens 2 ANLN 54443 Affinity Capture-MS Homo sapiens 3 H2AFJ 55766 Cross-Linking-MS (XL-MS) Homo sapiens 4 RPS27A 6233 Cross-Linking-MS (XL-MS) Homo sapiens 5 DNAJC11 55735 Affinity Capture-MS Homo sapiens 6 CEP170P1   Affinity Capture-MS Homo sapiens 7 NASP 4678 Two-hybrid Homo sapiens Two-hybrid Homo sapiens 8 H3F3A 3020 Cross-Linking-MS (XL-MS) Homo sapiens 9 KIF14 9928 Affinity Capture-MS Homo sapiens 10 CDK8 1024 Affinity Capture-MS Homo sapiens 11 OTUD1 220213 Affinity Capture-MS Homo sapiens 12 HIST1H4A 8359 Cross-Linking-MS (XL-MS) Homo sapiens 13 ECT2 1894 Affinity Capture-MS Homo sapiens 14 HIST1H1D 3007 Cross-Linking-MS (XL-MS) Homo sapiens 15 Fbl 14113 Affinity Capture-MS Mus musculus 16 MCM5 4174 Affinity Capture-MS Homo sapiens 17 PRMT5 10419 Two-hybrid Homo sapiens 18 PRMT7   Two-hybrid Homo sapiens 19 UBA52 7311 Cross-Linking-MS (XL-MS) Homo sapiens 20 HIST1H1T 3010 Cross-Linking-MS (XL-MS) Homo sapiens 21 RPL10 6134 Affinity Capture-MS Homo sapiens 22 KIF20A 10112 Affinity Capture-MS Homo sapiens 23 UBC 7316 Cross-Linking-MS (XL-MS) Homo sapiens 24 HIST2H2AC 8338 Cross-Linking-MS (XL-MS) Homo sapiens 25 SETMAR   Two-hybrid Homo sapiens 26 PHKG2 5261 Affinity Capture-MS Homo sapiens 27 HIST1H3A 8350 Cross-Linking-MS (XL-MS) Homo sapiens 28 SUV39H1   Two-hybrid Homo sapiens 29 SMYD3 64754 Two-hybrid Homo sapiens 30 AURKB 9212 Affinity Capture-MS Homo sapiens 31 WTAP 9589 Affinity Capture-MS Homo sapiens 32 CUL9   Affinity Capture-MS Homo sapiens 33 CHMP4C 92421 Affinity Capture-MS Homo sapiens 34 KDM1A 23028 Two-hybrid Homo sapiens 35 Srp72   Affinity Capture-MS Mus musculus 36 CHMP4B 128866 Affinity Capture-MS Homo sapiens 37 UBB 7314 Cross-Linking-MS (XL-MS) Homo sapiens 38 PRC1 9055 Affinity Capture-MS Homo sapiens 39 KIF23 9493 Affinity Capture-MS Homo sapiens 40 DNAJC9 23234 Two-hybrid Homo sapiens 41 CBX5 23468 Cross-Linking-MS (XL-MS) Homo sapiens 42 EFNA4   Affinity Capture-MS Homo sapiens 43 KDM4B   Two-hybrid Homo sapiens 44 METTL3   Affinity Capture-MS Homo sapiens 45 HIST1H1A 3024 Cross-Linking-MS (XL-MS) Homo sapiens 46 KIF11 3832 Affinity Capture-MS Homo sapiens 47 FBLIM1 54751 Two-hybrid Homo sapiens 48 KAT6A   Biochemical Activity Homo sapiens 49 CUL7 9820 Affinity Capture-MS Homo sapiens 50 PRMT6   Two-hybrid Homo sapiens 51 C9orf72   Affinity Capture-MS Homo sapiens 52 WHSC1L1   Two-hybrid Homo sapiens 53 FBXW8 26259 Affinity Capture-MS Homo sapiens 54 OBSL1 23363 Affinity Capture-MS Homo sapiens 55 PHF8   Affinity Capture-MS Homo sapiens 56 ABCE1 6059 Affinity Capture-MS Homo sapiens 57 SMYD1   Two-hybrid Homo sapiens 58 CHD4 1108 Affinity Capture-MS Homo sapiens 59 DAXX   Two-hybrid Homo sapiens 60 CCDC8   Affinity Capture-MS Homo sapiens 61 H2AFX 3014 Cross-Linking-MS (XL-MS) Homo sapiens View the network

Pathways in which H3F3C is involved

No pathways found