Gene description for FASN
Gene name fatty acid synthase
Gene symbol FASN
Other names/aliases FAS
OA-519
SDR27X1
Species Homo sapiens
 Database cross references - FASN
ExoCarta ExoCarta_2194
Vesiclepedia VP_2194
Entrez Gene 2194
HGNC 3594
MIM 600212
UniProt P49327  
 FASN identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34887515    
Breast cancer cells 34887515    
Breast milk 17641064    
Breast milk 17641064    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Keratinocytes 19530224    
Keratinocytes 19530224    
Liver cancer cells 25265333    
Liver cancer cells 25265333    
Liver cancer cells 25265333    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 22635005    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34887515    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Pluripotent stem cells 34108659    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal endothelial cells 34887515    
Serum 25265333    
Serum 25265333    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for FASN
Molecular Function
    RNA binding GO:0003723 HDA
    fatty acid synthase activity GO:0004312 EXP
    fatty acid synthase activity GO:0004312 IBA
    [acyl-carrier-protein] S-acetyltransferase activity GO:0004313 IDA
    [acyl-carrier-protein] S-malonyltransferase activity GO:0004314 IEA
    3-oxoacyl-[acyl-carrier-protein] synthase activity GO:0004315 IEA
    3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316 IEA
    protein binding GO:0005515 IPI
    fatty acyl-[ACP] hydrolase activity GO:0016297 IEA
    (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity GO:0019171 IEA
    phosphopantetheine binding GO:0031177 IEA
    cadherin binding GO:0045296 HDA
    enoyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0141148 IEA
Biological Process
    osteoblast differentiation GO:0001649 HDA
    glandular epithelial cell development GO:0002068 IEA
    fatty acid metabolic process GO:0006631 TAS
    fatty acid biosynthetic process GO:0006633 IBA
    fatty acid biosynthetic process GO:0006633 IEA
    inflammatory response GO:0006954 IEA
    ether lipid biosynthetic process GO:0008611 IEA
    neutrophil differentiation GO:0030223 IEA
    monocyte differentiation GO:0030224 IEA
    mammary gland development GO:0030879 IEA
    modulation by host of viral process GO:0044788 IDA
    fatty-acyl-CoA biosynthetic process GO:0046949 TAS
    cellular response to interleukin-4 GO:0071353 IEA
    establishment of endothelial intestinal barrier GO:0090557 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    Golgi apparatus GO:0005794 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IDA
    membrane GO:0016020 HDA
    melanosome GO:0042470 IEA
    glycogen granule GO:0042587 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified FASN in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
4
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
9
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 1206
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
ELISA
13
Experiment ID 1210
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name LM2-4175
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
14
Experiment ID 46
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|MHCII|CD81|CD86
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors "Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Colostrum
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
15
Experiment ID 48
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
HSC70|CD63|CD86|MHCII
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17641064    
Organism Homo sapiens
Experiment description Exosomes with immune modulatory features are present in human breast milk.
Authors "Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S"
Journal name JIMMU
Publication year 2007
Sample Breast milk
Sample name Breast milk - Mature milk
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.10-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
FACS
16
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
17
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
19
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
20
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
21
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
22
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
27
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
28
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
29
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
30
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
31
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
32
Experiment ID 1207
MISEV standards
✘ Biophysical techniques
✔
SDCBP|CD9|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name HCA-7 SC
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
33
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
38
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
41
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
46
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
47
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
48
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
49
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
50
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
51
Experiment ID 266
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Wild type
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
52
Experiment ID 268
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx-null HBV replicon plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
53
Experiment ID 267
MISEV standards
✘ Biophysical techniques
✔
TSG101|Alix
Enriched markers
✔
CANX|HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Liver cancer cells
Sample name Huh-7 - Transfected with HBx plasmids
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
54
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
55
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
56
Experiment ID 200
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|TSG101|Alix|GAPDH
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22635005    
Organism Homo sapiens
Experiment description Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Authors "Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D."
Journal name Nat Med
Publication year 2012
Sample Melanoma cells
Sample name B16-F10
SK-MEL-202
SK-MEL035
SK-MEL-265
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
58
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
59
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
60
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
61
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
62
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
63
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
64
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
65
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
66
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
67
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
68
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
69
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
70
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
71
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
72
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
73
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
74
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
75
Experiment ID 1205
MISEV standards
✘ Biophysical techniques
✔
FLOT1|SDCBP
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
76
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
77
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
78
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
79
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
80
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
81
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
82
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
83
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
84
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
85
Experiment ID 142
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
86
Experiment ID 143
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
87
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
88
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
89
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
90
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
91
Experiment ID 1208
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Retinal endothelial cells
Sample name HREC
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
92
Experiment ID 269
MISEV standards
✘ Biophysical techniques
✔
Alix
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Serum
Sample name Serum - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
93
Experiment ID 270
MISEV standards
✘ Biophysical techniques
✔
Alix
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25265333    
Organism Homo sapiens
Experiment description Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Authors "Zhao X, Wu Y, Duan J, Ma Y, Shen Z, Wei L, Cui X, Zhang J, Xie Y, Liu J"
Journal name J Proteome Res
Publication year 2014
Sample Serum
Sample name Serum - HBV infected
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
94
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
95
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
96
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
97
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
98
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
99
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FASN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLEKHA3  
Positive Genetic Homo sapiens
Negative Genetic Homo sapiens
2 SLC25A13 10165
Negative Genetic Homo sapiens
3 RLF 6018
Negative Genetic Homo sapiens
4 ISG15 9636
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 RGL4  
Negative Genetic Homo sapiens
6 MYLIP  
Positive Genetic Homo sapiens
7 SLC35A1 10559
Negative Genetic Homo sapiens
8 NPRL2  
Negative Genetic Homo sapiens
9 SHC1 6464
Affinity Capture-MS Homo sapiens
10 C1orf27 54953
Negative Genetic Homo sapiens
11 SLC12A1 6557
Positive Genetic Homo sapiens
12 ALG12  
Negative Genetic Homo sapiens
13 LDHB 3945
Negative Genetic Homo sapiens
14 KLLN  
Positive Genetic Homo sapiens
15 RIN3  
Affinity Capture-MS Homo sapiens
16 PSMA4 5685
Co-fractionation Homo sapiens
17 MCM9 254394
Negative Genetic Homo sapiens
18 GABPB1  
Negative Genetic Homo sapiens
19 CAP1 10487
Co-fractionation Homo sapiens
20 PIGH  
Positive Genetic Homo sapiens
21 ACTC1 70
Affinity Capture-MS Homo sapiens
22 GPATCH8  
Negative Genetic Homo sapiens
23 NMNAT1  
Negative Genetic Homo sapiens
24 SMG7  
Negative Genetic Homo sapiens
25 MAP4 4134
Co-fractionation Homo sapiens
26 KIF20A 10112
Affinity Capture-MS Homo sapiens
27 SPNS1 83985
Negative Genetic Homo sapiens
28 MAD2L1BP  
Negative Genetic Homo sapiens
29 MAP4K4 9448
Negative Genetic Homo sapiens
30 WAC  
Negative Genetic Homo sapiens
31 CYB5R4 51167
Negative Genetic Homo sapiens
32 EIF1 10209
Negative Genetic Homo sapiens
33 PPAT 5471
Positive Genetic Homo sapiens
34 SBDS 51119
Positive Genetic Homo sapiens
35 LPCAT1 79888
Negative Genetic Homo sapiens
36 MRPS18C  
Positive Genetic Homo sapiens
37 TCEB3 6924
Positive Genetic Homo sapiens
38 PTRH2 51651
Positive Genetic Homo sapiens
39 GPATCH4 54865
Positive Genetic Homo sapiens
40 MED13 9969
Positive Genetic Homo sapiens
41 TAX1BP3 30851
Positive Genetic Homo sapiens
42 MEAF6  
Positive Genetic Homo sapiens
43 BRD4 23476
Negative Genetic Homo sapiens
44 DPM1 8813
Negative Genetic Homo sapiens
45 GTF2E2  
Negative Genetic Homo sapiens
46 HECA  
Negative Genetic Homo sapiens
47 GFPT1 2673
Co-fractionation Homo sapiens
Negative Genetic Homo sapiens
48 NDRG1 10397
Affinity Capture-MS Homo sapiens
49 PPP6C 5537
Affinity Capture-MS Homo sapiens
50 ZC3H7A  
Positive Genetic Homo sapiens
51 OR2G6  
Negative Genetic Homo sapiens
52 ESRRG  
Positive Genetic Homo sapiens
53 LTBP1 4052
Negative Genetic Homo sapiens
54 AI837181  
Affinity Capture-MS Mus musculus
55 SEL1L 6400
Negative Genetic Homo sapiens
56 UBL4A 8266
Positive Genetic Homo sapiens
57 DHDDS  
Positive Genetic Homo sapiens
58 HSPH1 10808
Positive Genetic Homo sapiens
59 ETFA 2108
Negative Genetic Homo sapiens
60 TLK1  
Negative Genetic Homo sapiens
61 MARCH5  
Negative Genetic Homo sapiens
62 C15orf57  
Negative Genetic Homo sapiens
63 PPP4R4 57718
Positive Genetic Homo sapiens
64 ACSL1 2180
Negative Genetic Homo sapiens
Affinity Capture-MS Homo sapiens
65 LAMTOR4 389541
Positive Genetic Homo sapiens
66 KPTN  
Negative Genetic Homo sapiens
67 PRKAG1 5571
Negative Genetic Homo sapiens
68 MLXIPL  
Affinity Capture-MS Homo sapiens
69 KIF3A 11127
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 KIF14 9928
Affinity Capture-MS Homo sapiens
71 CLASP2 23122
Negative Genetic Homo sapiens
72 FBXL5  
Negative Genetic Homo sapiens
73 ACTG1 71
Positive Genetic Homo sapiens
74 KLF16  
Positive Genetic Homo sapiens
75 TAZ  
Positive Genetic Homo sapiens
76 CHMP4C 92421
Affinity Capture-MS Homo sapiens
77 AURKA 6790
Negative Genetic Homo sapiens
78 WNK1 65125
Positive Genetic Homo sapiens
79 CNOT11 55571
Negative Genetic Homo sapiens
80 LIN28B  
Positive Genetic Homo sapiens
81 CRY1  
Affinity Capture-MS Homo sapiens
82 USP14 9097
Negative Genetic Homo sapiens
83 RAB14 51552
Positive Genetic Homo sapiens
84 PELO 53918
Positive Genetic Homo sapiens
85 APLP2 334
Positive Genetic Homo sapiens
86 FAM122A  
Positive Genetic Homo sapiens
87 HACD3 51495
Negative Genetic Homo sapiens
88 VRK1 7443
Negative Genetic Homo sapiens
89 RBM7  
Positive Genetic Homo sapiens
Negative Genetic Homo sapiens
90 ACP2 53
Co-fractionation Homo sapiens
91 CAMK2G 818
Positive Genetic Homo sapiens
92 SOWAHB  
Negative Genetic Homo sapiens
93 PABPC1 26986
Co-fractionation Homo sapiens
94 CDH1 999
Proximity Label-MS Homo sapiens
95 MYDGF 56005
Negative Genetic Homo sapiens
96 CLCC1 23155
Negative Genetic Homo sapiens
97 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 KCNK2  
Negative Genetic Homo sapiens
99 TRIM21 6737
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
100 SLX4  
Affinity Capture-MS Homo sapiens
101 RASEF  
Negative Genetic Homo sapiens
102 SAR1B 51128
Affinity Capture-MS Homo sapiens
103 GFPT2 9945
Co-fractionation Homo sapiens
104 TRAPPC2L 51693
Negative Genetic Homo sapiens
105 TRAPPC13 80006
Negative Genetic Homo sapiens
106 NOS2  
Affinity Capture-MS Homo sapiens
107 YWHAQ 10971
Reconstituted Complex Homo sapiens
108 Mapk13  
Affinity Capture-MS Mus musculus
109 MTFMT  
Positive Genetic Homo sapiens
110 CUL2 8453
Co-fractionation Homo sapiens
111 UBE2J1 51465
Negative Genetic Homo sapiens
112 PSME1 5720
Co-fractionation Homo sapiens
113 DDX39B 7919
Affinity Capture-MS Homo sapiens
114 XYLT2 64132
Positive Genetic Homo sapiens
115 MGAT2 4247
Negative Genetic Homo sapiens
116 C19orf53  
Positive Genetic Homo sapiens
117 CYP27A1  
Co-fractionation Homo sapiens
118 PAPSS2 9060
Positive Genetic Homo sapiens
119 PTAR1 375743
Negative Genetic Homo sapiens
120 ZFP36L2 678
Negative Genetic Homo sapiens
121 ANLN 54443
Affinity Capture-MS Homo sapiens
122 TRIP13 9319
Negative Genetic Homo sapiens
123 PHLPP1  
Proximity Label-MS Homo sapiens
124 BRD7  
Positive Genetic Homo sapiens
125 METTL23  
Positive Genetic Homo sapiens
126 RNF40 9810
Co-fractionation Homo sapiens
127 GJD2  
Negative Genetic Homo sapiens
128 RPS19 6223
Cross-Linking-MS (XL-MS) Homo sapiens
129 WBSCR16  
Negative Genetic Homo sapiens
130 TMEM30A 55754
Negative Genetic Homo sapiens
131 UFC1 51506
Negative Genetic Homo sapiens
132 TARBP1 6894
Co-fractionation Homo sapiens
133 AHCYL1 10768
Positive Genetic Homo sapiens
134 PITRM1 10531
Positive Genetic Homo sapiens
135 SOX12  
Negative Genetic Homo sapiens
136 SDHA 6389
Affinity Capture-MS Homo sapiens
137 BOLA3  
Negative Genetic Homo sapiens
138 SIRT7  
Affinity Capture-MS Homo sapiens
139 ZNF622 90441
Positive Genetic Homo sapiens
140 KCMF1 56888
Negative Genetic Homo sapiens
141 RNF130  
Positive Genetic Homo sapiens
142 PRKAR1A 5573
Co-fractionation Homo sapiens
143 ANKRD32  
Negative Genetic Homo sapiens
144 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 HSPA14 51182
Positive Genetic Homo sapiens
146 C9orf9  
Positive Genetic Homo sapiens
147 COQ4  
Positive Genetic Homo sapiens
148 CSNK2A1 1457
Negative Genetic Homo sapiens
149 CCT8 10694
Co-fractionation Homo sapiens
150 PHKG2 5261
Affinity Capture-MS Homo sapiens
151 AAAS 8086
Positive Genetic Homo sapiens
152 CHEK2  
Positive Genetic Homo sapiens
153 PIK3C2B 5287
Co-fractionation Homo sapiens
154 PABPC4L 132430
Negative Genetic Homo sapiens
155 PDGFRA 5156
Positive Genetic Homo sapiens
156 SLTM 79811
Positive Genetic Homo sapiens
157 FN1 2335
Affinity Capture-MS Homo sapiens
158 MTF1  
Negative Genetic Homo sapiens
159 STRAP 11171
Positive Genetic Homo sapiens
160 PPHLN1  
Negative Genetic Homo sapiens
161 PRDM10  
Negative Genetic Homo sapiens
162 ATXN2L 11273
Positive Genetic Homo sapiens
163 HNRNPR 10236
Positive Genetic Homo sapiens
164 DPH5 51611
Positive Genetic Homo sapiens
165 PCBP1 5093
Proximity Label-MS Homo sapiens
166 TMED10 10972
Negative Genetic Homo sapiens
167 RPA3 6119
Proximity Label-MS Homo sapiens
168 EIF2D 1939
Positive Genetic Homo sapiens
169 AHR 196
Positive Genetic Homo sapiens
170 DLST 1743
Affinity Capture-MS Homo sapiens
171 ABCC1 4363
Co-fractionation Homo sapiens
172 PHF5A 84844
Negative Genetic Homo sapiens
173 HSPA1A 3303
Co-fractionation Homo sapiens
174 LCMT1 51451
Negative Genetic Homo sapiens
175 UBE2J2 118424
Negative Genetic Homo sapiens
176 CCDC101  
Positive Genetic Homo sapiens
177 FAM169A  
Positive Genetic Homo sapiens
178 SGTA 6449
Positive Genetic Homo sapiens
179 SYS1  
Negative Genetic Homo sapiens
180 ILK 3611
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 CTNNA1 1495
Co-fractionation Homo sapiens
182 CSDE1 7812
Co-fractionation Homo sapiens
183 SIN3B  
Negative Genetic Homo sapiens
184 SCAPER  
Negative Genetic Homo sapiens
185 HEATR1 55127
Negative Genetic Homo sapiens
Positive Genetic Homo sapiens
186 ARID2  
Positive Genetic Homo sapiens
187 TPM4 7171
Co-fractionation Homo sapiens
188 CEPT1 10390
Negative Genetic Homo sapiens
189 GRB2 2885
Positive Genetic Homo sapiens
190 HAUS3  
Negative Genetic Homo sapiens
191 HK2 3099
Positive Genetic Homo sapiens
192 AIMP1 9255
Co-fractionation Homo sapiens
193 NOSIP 51070
Negative Genetic Homo sapiens
194 CDC25A  
Positive Genetic Homo sapiens
195 FASN 2194
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
196 BTBD7  
Negative Genetic Homo sapiens
197 Tubg1 103733
Affinity Capture-MS Mus musculus
198 SLC35A2  
Negative Genetic Homo sapiens
199 SUPT20H 55578
Positive Genetic Homo sapiens
200 GSS 2937
Negative Genetic Homo sapiens
201 CDK8 1024
Positive Genetic Homo sapiens
202 MBD3 53615
Positive Genetic Homo sapiens
203 THOC3  
Negative Genetic Homo sapiens
204 WWOX 51741
Negative Genetic Homo sapiens
205 TCERG1 10915
Cross-Linking-MS (XL-MS) Homo sapiens
206 MFSD2A  
Negative Genetic Homo sapiens
207 FBXO21  
Negative Genetic Homo sapiens
208 CKAP2L  
Negative Genetic Homo sapiens
209 TAF6L 10629
Positive Genetic Homo sapiens
210 GNA13 10672
Negative Genetic Homo sapiens
211 PTDSS1 9791
Positive Genetic Homo sapiens
212 TTK 7272
Negative Genetic Homo sapiens
213 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
214 SALL1 6299
Negative Genetic Homo sapiens
215 PAPOLG  
Positive Genetic Homo sapiens
216 SIRT1  
Co-fractionation Homo sapiens
217 RPL35 11224
Positive Genetic Homo sapiens
218 ATAD3A 55210
Negative Genetic Homo sapiens
219 ALG6  
Negative Genetic Homo sapiens
220 RABL3 285282
Negative Genetic Homo sapiens
221 HACD2 201562
Negative Genetic Homo sapiens
222 RAB2A 5862
Negative Genetic Homo sapiens
223 HIC2 23119
Positive Genetic Homo sapiens
224 CDK4 1019
Positive Genetic Homo sapiens
225 RAD21 5885
Affinity Capture-Western Homo sapiens
226 PAPSS1 9061
Negative Genetic Homo sapiens
227 FECH 2235
Negative Genetic Homo sapiens
228 CDC16 8881
Negative Genetic Homo sapiens
229 LDLR 3949
Negative Genetic Homo sapiens
Negative Genetic Homo sapiens
230 ZNRD1  
Positive Genetic Homo sapiens
231 MANF 7873
Negative Genetic Homo sapiens
232 CUL7 9820
Affinity Capture-MS Homo sapiens
233 C11orf30  
Negative Genetic Homo sapiens
234 ADRM1 11047
Positive Genetic Homo sapiens
Co-fractionation Homo sapiens
235 GATAD1  
Negative Genetic Homo sapiens
236 MTF2  
Negative Genetic Homo sapiens
237 SLC7A1 6541
Positive Genetic Homo sapiens
238 HSPA5 3309
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
239 VPS72  
Negative Genetic Homo sapiens
240 SESN2 83667
Negative Genetic Homo sapiens
241 KCTD5 54442
Negative Genetic Homo sapiens
242 ALKBH8  
Positive Genetic Homo sapiens
243 OR2F2  
Negative Genetic Homo sapiens
244 UBE3D  
Positive Genetic Homo sapiens
245 PSMD3 5709
Co-fractionation Homo sapiens
246 MORC2  
Negative Genetic Homo sapiens
247 TLE1 7088
Positive Genetic Homo sapiens
248 TADA1  
Positive Genetic Homo sapiens
249 SMC3 9126
Negative Genetic Homo sapiens
250 KIF23 9493
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
251 CNNM3 26505
Negative Genetic Homo sapiens
252 SPRTN  
Affinity Capture-MS Homo sapiens
253 DPH2 1802
Positive Genetic Homo sapiens
254 HSPA6 3310
Co-fractionation Homo sapiens
255 TSC2 7249
Negative Genetic Homo sapiens
256 EIF3K 27335
Negative Genetic Homo sapiens
257 NUP188 23511
Negative Genetic Homo sapiens
258 MRPL14 64928
Negative Genetic Homo sapiens
259 NAA40  
Negative Genetic Homo sapiens
260 BTF3 689
Affinity Capture-MS Homo sapiens
261 C2orf72  
Negative Genetic Homo sapiens
262 NHLRC2 374354
Positive Genetic Homo sapiens
263 CCL11  
Negative Genetic Homo sapiens
264 SPTLC1 10558
Positive Genetic Homo sapiens
265 HSP90AB1 3326
Affinity Capture-MS Homo sapiens
266 GPR107 57720
Negative Genetic Homo sapiens
267 EIF4A1 1973
Positive Genetic Homo sapiens
268 CCT6B 10693
Co-fractionation Homo sapiens
269 CAND1 55832
Negative Genetic Homo sapiens
270 SYVN1 84447
Negative Genetic Homo sapiens
271 HYPK 25764
Positive Genetic Homo sapiens
272 VPS54  
Negative Genetic Homo sapiens
273 KIAA1598 57698
Co-fractionation Homo sapiens
274 ATP5L 10632
Positive Genetic Homo sapiens
275 TGFBR1 7046
Negative Genetic Homo sapiens
276 RBM26 64062
Positive Genetic Homo sapiens
277 RPS18 6222
Positive Genetic Homo sapiens
278 MBTD1  
Negative Genetic Homo sapiens
279 ARL6IP6  
Affinity Capture-MS Homo sapiens
280 GMPR 2766
Positive Genetic Homo sapiens
281 MAML2  
Negative Genetic Homo sapiens
282 C11orf73 51501
Positive Genetic Homo sapiens
283 HELZ 9931
Negative Genetic Homo sapiens
284 MPHOSPH8 54737
Negative Genetic Homo sapiens
285 SLC6A9 6536
Negative Genetic Homo sapiens
286 PRC1 9055
Affinity Capture-MS Homo sapiens
287 TMED2 10959
Negative Genetic Homo sapiens
288 KHDRBS1 10657
Negative Genetic Homo sapiens
289 MLST8 64223
Positive Genetic Homo sapiens
290 OBSL1 23363
Affinity Capture-MS Homo sapiens
291 ZFAT  
Negative Genetic Homo sapiens
292 PLCG1 5335
Negative Genetic Homo sapiens
293 PAGR1  
Negative Genetic Homo sapiens
294 ANAPC11  
Negative Genetic Homo sapiens
295 FBXO11  
Positive Genetic Homo sapiens
296 STIP1 10963
Positive Genetic Homo sapiens
297 FIBP 9158
Negative Genetic Homo sapiens
298 SMPD1 6609
Negative Genetic Homo sapiens
299 DNAJC7 7266
Affinity Capture-MS Homo sapiens
300 VCAM1 7412
Affinity Capture-MS Homo sapiens
301 OR4D1  
Negative Genetic Homo sapiens
302 HSD17B4 3295
Affinity Capture-MS Homo sapiens
303 ASF1A 25842
Negative Genetic Homo sapiens
304 PLS3 5358
Co-fractionation Homo sapiens
305 UGP2 7360
Negative Genetic Homo sapiens
306 RRAGA 10670
Positive Genetic Homo sapiens
307 DYNC1H1 1778
Co-fractionation Homo sapiens
308 PIM3  
Positive Genetic Homo sapiens
309 ITFG2  
Negative Genetic Homo sapiens
310 GTF2I 2969
Negative Genetic Homo sapiens
311 PFN1 5216
Negative Genetic Homo sapiens
312 XPO1 7514
Negative Genetic Homo sapiens
313 PHF10  
Positive Genetic Homo sapiens
314 R3HDM1  
Positive Genetic Homo sapiens
315 MIB1 57534
Negative Genetic Homo sapiens
316 MAPK3 5595
Affinity Capture-MS Homo sapiens
317 PCED1B  
Positive Genetic Homo sapiens
318 USP10 9100
Affinity Capture-MS Homo sapiens
319 BAK1 578
Positive Genetic Homo sapiens
320 SCAI  
Negative Genetic Homo sapiens
321 HSD11B1L  
Positive Genetic Homo sapiens
322 RUFY1 80230
Positive Genetic Homo sapiens
323 CDK5 1020
Negative Genetic Homo sapiens
324 SCG3  
Positive Genetic Homo sapiens
325 TRA2A 29896
Negative Genetic Homo sapiens
326 NHS 4810
Positive Genetic Homo sapiens
327 TEAD3  
Affinity Capture-MS Homo sapiens
328 SLC39A9 55334
Negative Genetic Homo sapiens
329 BAG6 7917
Negative Genetic Homo sapiens
330 ATF4  
Positive Genetic Homo sapiens
331 ALDH18A1 5832
Negative Genetic Homo sapiens
332 C12orf49  
Negative Genetic Homo sapiens
Negative Genetic Homo sapiens
333 CCT6A 908
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
334 IWS1  
Negative Genetic Homo sapiens
335 UBP1 7342
Positive Genetic Homo sapiens
336 NAA35 60560
Negative Genetic Homo sapiens
337 NELFE 7936
Positive Genetic Homo sapiens
338 TRPM7 54822
Positive Genetic Homo sapiens
339 PPP2CA 5515
Negative Genetic Homo sapiens
340 RNF187  
Positive Genetic Homo sapiens
341 OR13C8  
Positive Genetic Homo sapiens
342 Bag2  
Affinity Capture-MS Mus musculus
343 PACRGL  
Positive Genetic Homo sapiens
344 ZFP41  
Positive Genetic Homo sapiens
345 KLC1 3831
Co-fractionation Homo sapiens
346 MAGOH 4116
Affinity Capture-MS Homo sapiens
347 IARS 3376
Co-fractionation Homo sapiens
348 MCUR1 63933
Negative Genetic Homo sapiens
349 GET4 51608
Negative Genetic Homo sapiens
350 KLF12  
Positive Genetic Homo sapiens
351 CYLD  
Affinity Capture-MS Homo sapiens
352 ZNF609  
Positive Genetic Homo sapiens
353 PTGR2 145482
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 EIF4B 1975
Co-fractionation Homo sapiens
Positive Genetic Homo sapiens
355 FBXL4 26235
Affinity Capture-MS Homo sapiens
Positive Genetic Homo sapiens
356 COLGALT1 79709
Co-fractionation Homo sapiens
357 CGGBP1 8545
Positive Genetic Homo sapiens
358 RECQL5  
Negative Genetic Homo sapiens
359 PTPN11 5781
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
360 PER2  
Proximity Label-MS Homo sapiens
361 SGPL1 8879
Negative Genetic Homo sapiens
362 TMED9 54732
Negative Genetic Homo sapiens
363 KHSRP 8570
Negative Genetic Homo sapiens
364 ACLY 47
Co-fractionation Homo sapiens
365 EAF1  
Negative Genetic Homo sapiens
366 CCNC  
Positive Genetic Homo sapiens
367 TP53BP1 7158
Affinity Capture-MS Homo sapiens
368 RICTOR 253260
Positive Genetic Homo sapiens
369 TPK1  
Negative Genetic Homo sapiens
370 NCBP2 22916
Positive Genetic Homo sapiens
371 FITM2  
Negative Genetic Homo sapiens
372 SUMO4 387082
Positive Genetic Homo sapiens
373 SRSF5 6430
Positive Genetic Homo sapiens
Negative Genetic Homo sapiens
374 MEX3A  
Affinity Capture-RNA Homo sapiens
375 CSRP2BP  
Positive Genetic Homo sapiens
376 YLPM1 56252
Positive Genetic Homo sapiens
377 TGIF1  
Negative Genetic Homo sapiens
378 HSD17B10 3028
Affinity Capture-MS Homo sapiens
379 FOXL1  
Affinity Capture-MS Homo sapiens
380 METTL3  
Affinity Capture-MS Homo sapiens
381 GGNBP2  
Negative Genetic Homo sapiens
382 LARS 51520
Co-fractionation Homo sapiens
383 TBC1D7  
Negative Genetic Homo sapiens
384 CCNT2  
Positive Genetic Homo sapiens
385 PPIL3 53938
Negative Genetic Homo sapiens
386 CDK2 1017
Affinity Capture-MS Homo sapiens
Positive Genetic Homo sapiens
387 BIRC6 57448
Negative Genetic Homo sapiens
388 WDR24  
Positive Genetic Homo sapiens
389 TADA2A  
Positive Genetic Homo sapiens
390 PPP2R1A 5518
Co-fractionation Homo sapiens
391 PGM3 5238
Negative Genetic Homo sapiens
392 FUS 2521
Affinity Capture-MS Homo sapiens
393 ZSWIM6  
Negative Genetic Homo sapiens
394 NIPBL 25836
Negative Genetic Homo sapiens
395 CRAMP1L 57585
Negative Genetic Homo sapiens
396 ACAD9 28976
Negative Genetic Homo sapiens
397 NUAK1  
Negative Genetic Homo sapiens
398 SNW1 22938
Affinity Capture-MS Homo sapiens
399 DDRGK1 65992
Affinity Capture-MS Homo sapiens
400 Yap1  
Reconstituted Complex Mus musculus
401 UBE2T  
Negative Genetic Homo sapiens
402 MECOM 2122
Positive Genetic Homo sapiens
403 RAB5C 5878
Negative Genetic Homo sapiens
404 TADA2B  
Positive Genetic Homo sapiens
405 TAF4 6874
Negative Genetic Homo sapiens
406 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
407 DSP 1832
Co-fractionation Homo sapiens
408 GSR 2936
Positive Genetic Homo sapiens
409 RAB18 22931
Negative Genetic Homo sapiens
410 RPL13 6137
Positive Genetic Homo sapiens
411 MUC12  
Negative Genetic Homo sapiens
412 C10orf90 118611
Positive Genetic Homo sapiens
413 PRKCSH 5589
Negative Genetic Homo sapiens
414 SLC38A2 54407
Positive Genetic Homo sapiens
415 LINS  
Positive Genetic Homo sapiens
416 PARP1 142
Negative Genetic Homo sapiens
417 ILF3 3609
Negative Genetic Homo sapiens
418 TP53 7157
Affinity Capture-MS Homo sapiens
419 UBA5 79876
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
420 TTC4  
Positive Genetic Homo sapiens
421 TMEM68  
Negative Genetic Homo sapiens
422 SLCO4A1 28231
Negative Genetic Homo sapiens
423 UBTF 7343
Positive Genetic Homo sapiens
424 IER3IP1 51124
Positive Genetic Homo sapiens
425 KEAP1 9817
Negative Genetic Homo sapiens
426 LIN28A  
Negative Genetic Homo sapiens
427 DEPDC5  
Negative Genetic Homo sapiens
428 C1orf35  
Negative Genetic Homo sapiens
429 UBE4A 9354
Positive Genetic Homo sapiens
430 SCPEP1 59342
Co-fractionation Homo sapiens
431 DMAP1 55929
Negative Genetic Homo sapiens
432 TSC1 7248
Negative Genetic Homo sapiens
433 TMEM147 10430
Negative Genetic Homo sapiens
434 CDK6 1021
Positive Genetic Homo sapiens
435 MED1 5469
Positive Genetic Homo sapiens
436 RPS5 6193
Positive Genetic Homo sapiens
437 REPIN1  
Positive Genetic Homo sapiens
438 EDEM2  
Positive Genetic Homo sapiens
439 BSG 682
Positive Genetic Homo sapiens
440 POU2F1 5451
Positive Genetic Homo sapiens
441 MAPK6  
Positive Genetic Homo sapiens
442 AUP1 550
Negative Genetic Homo sapiens
443 RABGEF1 27342
Negative Genetic Homo sapiens
444 WDR43 23160
Positive Genetic Homo sapiens
445 ADIPOQ 9370
Two-hybrid Homo sapiens
446 CDV3 55573
Positive Genetic Homo sapiens
447 EIF3J 8669
Positive Genetic Homo sapiens
448 NF2 4771
Positive Genetic Homo sapiens
449 ACSL3 2181
Negative Genetic Homo sapiens
450 PSMF1 9491
Negative Genetic Homo sapiens
451 TRIB3  
Negative Genetic Homo sapiens
452 C2CD5 9847
Negative Genetic Homo sapiens
453 CEP85  
Negative Genetic Homo sapiens
454 SMARCAL1  
Negative Genetic Homo sapiens
455 ZBED4 9889
Positive Genetic Homo sapiens
456 DLD 1738
Affinity Capture-MS Homo sapiens
457 PRMT1 3276
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
458 VEZF1  
Negative Genetic Homo sapiens
459 MRPS9 64965
Negative Genetic Homo sapiens
460 ATP13A1 57130
Negative Genetic Homo sapiens
461 CCND3  
Positive Genetic Homo sapiens
462 STRA6 64220
Negative Genetic Homo sapiens
463 DACH2  
Positive Genetic Homo sapiens
464 BAHD1  
Negative Genetic Homo sapiens
465 NUDC 10726
Negative Genetic Homo sapiens
Co-fractionation Homo sapiens
466 HNRNPC 3183
Cross-Linking-MS (XL-MS) Homo sapiens
467 CBX3 11335
Positive Genetic Homo sapiens
468 ZFX  
Negative Genetic Homo sapiens
469 MTCH1 23787
Co-fractionation Homo sapiens
470 RAB1A 5861
Negative Genetic Homo sapiens
Co-fractionation Homo sapiens
471 SMC6  
Negative Genetic Homo sapiens
472 MTX1 4580
Positive Genetic Homo sapiens
473 PFKP 5214
Positive Genetic Homo sapiens
474 SP1  
Positive Genetic Homo sapiens
475 GATA2  
Positive Genetic Homo sapiens
476 VPS52 6293
Negative Genetic Homo sapiens
477 TAS2R42  
Positive Genetic Homo sapiens
478 NBAS 51594
Negative Genetic Homo sapiens
479 EFTUD1 79631
Positive Genetic Homo sapiens
480 C15orf40  
Negative Genetic Homo sapiens
481 SSB 6741
Co-fractionation Homo sapiens
482 SAMD1  
Positive Genetic Homo sapiens
483 HNRNPCL1 343069
Cross-Linking-MS (XL-MS) Homo sapiens
484 OR4K1  
Positive Genetic Homo sapiens
485 PSMD10 5716
Co-fractionation Homo sapiens
486 PTPN1 5770
Co-fractionation Homo sapiens
487 MBTPS2  
Negative Genetic Homo sapiens
488 ANKS1A 23294
Negative Genetic Homo sapiens
489 GLTSCR1 29998
Negative Genetic Homo sapiens
490 MRE11A 4361
Negative Genetic Homo sapiens
491 AMHR2  
Negative Genetic Homo sapiens
492 CAPZB 832
Affinity Capture-MS Homo sapiens
493 NDUFB9 4715
Positive Genetic Homo sapiens
494 DBF4  
Negative Genetic Homo sapiens
495 HEATR3 55027
Positive Genetic Homo sapiens
496 PCNT  
Negative Genetic Homo sapiens
497 MCM2 4171
Affinity Capture-MS Homo sapiens
498 SUV39H1  
Positive Genetic Homo sapiens
499 TRIM56 81844
Negative Genetic Homo sapiens
500 BRPF3  
Positive Genetic Homo sapiens
501 POLR1E  
Positive Genetic Homo sapiens
502 EWSR1 2130
Two-hybrid Homo sapiens
503 MCM6 4175
Negative Genetic Homo sapiens
504 SF3A2 8175
Affinity Capture-MS Homo sapiens
505 CLEC14A  
Negative Genetic Homo sapiens
506 SLC34A3  
Negative Genetic Homo sapiens
507 COIL  
Negative Genetic Homo sapiens
508 C20orf24  
Negative Genetic Homo sapiens
509 MARS 4141
Co-fractionation Homo sapiens
510 ATG9B  
Affinity Capture-MS Homo sapiens
511 VPS16 64601
Negative Genetic Homo sapiens
512 TFCP2 7024
Affinity Capture-MS Homo sapiens
513 GRIK2  
Negative Genetic Homo sapiens
514 ATP13A3 79572
Negative Genetic Homo sapiens
515 LMAN1L  
Negative Genetic Homo sapiens
516 DPH1  
Positive Genetic Homo sapiens
517 HSPA8 3312
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
518 NCOA1  
Positive Genetic Homo sapiens
519 NSDHL 50814
Affinity Capture-MS Homo sapiens
520 INSIG2  
Affinity Capture-MS Homo sapiens
521 CHD1 1105
Negative Genetic Homo sapiens
522 HSPBP1 23640
Co-fractionation Homo sapiens
523 UBR4 23352
Negative Genetic Homo sapiens
524 SLC52A2 79581
Negative Genetic Homo sapiens
525 NSUN2 54888
Positive Genetic Homo sapiens
526 ACAT2 39
Negative Genetic Homo sapiens
527 S100A2 6273
Co-fractionation Homo sapiens
528 SCAF1  
Negative Genetic Homo sapiens
529 ZBTB40  
Positive Genetic Homo sapiens
530 MCM3AP  
Negative Genetic Homo sapiens
531 XRCC2  
Negative Genetic Homo sapiens
532 CNOT2  
Negative Genetic Homo sapiens
533 FASTKD5  
Negative Genetic Homo sapiens
534 NDUFB7 4713
Positive Genetic Homo sapiens
535 FOXI2  
Affinity Capture-MS Homo sapiens
536 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
537 RPS10 6204
Positive Genetic Homo sapiens
538 TMEM165 55858
Negative Genetic Homo sapiens
539 XRN1 54464
Negative Genetic Homo sapiens
540 SZT2 23334
Negative Genetic Homo sapiens
541 LIN52  
Negative Genetic Homo sapiens
542 KPNA4 3840
Negative Genetic Homo sapiens
Positive Genetic Homo sapiens
543 ACACA 31
Negative Genetic Homo sapiens
544 PLOD2 5352
Co-fractionation Homo sapiens
545 NUDT4 11163
Positive Genetic Homo sapiens
546 PDCD5 9141
Positive Genetic Homo sapiens
547 CCDC51 79714
Positive Genetic Homo sapiens
548 CHMP4B 128866
Affinity Capture-MS Homo sapiens
549 CNOT1 23019
Negative Genetic Homo sapiens
550 NTRK1 4914
Affinity Capture-MS Homo sapiens
551 GLI3 2737
Positive Genetic Homo sapiens
552 ARNT 405
Positive Genetic Homo sapiens
553 LDLRAP1 26119
Negative Genetic Homo sapiens
554 CARM1 10498
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
555 RPL36 25873
Positive Genetic Homo sapiens
556 KIF11 3832
Affinity Capture-MS Homo sapiens
557 RAB3GAP1 22930
Negative Genetic Homo sapiens
558 SMS 6611
Negative Genetic Homo sapiens
Co-fractionation Homo sapiens
559 SUB1 10923
Positive Genetic Homo sapiens
560 C1orf115  
Positive Genetic Homo sapiens
561 TECR 9524
Negative Genetic Homo sapiens
562 PHF12  
Negative Genetic Homo sapiens
563 RAB10 10890
Negative Genetic Homo sapiens
564 UROS 7390
Negative Genetic Homo sapiens
565 PSMD2 5708
Positive Genetic Homo sapiens
566 HNRNPA3 220988
Co-fractionation Homo sapiens
567 HDAC5 10014
Affinity Capture-MS Homo sapiens
568 DNM1L 10059
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
569 KDM5A  
Negative Genetic Homo sapiens
570 BZW1 9689
Positive Genetic Homo sapiens
571 IPO9 55705
Positive Genetic Homo sapiens
572 TEX43  
Positive Genetic Homo sapiens
573 RPL11 6135
Positive Genetic Homo sapiens
574 SLC4A7 9497
Positive Genetic Homo sapiens
575 HNRNPCL3 649330
Cross-Linking-MS (XL-MS) Homo sapiens
576 HNRNPDL 9987
Co-fractionation Homo sapiens
577 SLC16A1 6566
Positive Genetic Homo sapiens
578 HABP4  
Positive Genetic Homo sapiens
579 ZBTB2 57621
Positive Genetic Homo sapiens
580 CCNA2 890
Positive Genetic Homo sapiens
581 PGLS 25796
Positive Genetic Homo sapiens
582 AHCY 191
Co-fractionation Homo sapiens
583 TSSC1 7260
Negative Genetic Homo sapiens
584 KMT2A  
Positive Genetic Homo sapiens
585 RASGRP4  
Positive Genetic Homo sapiens
586 RERE 473
Positive Genetic Homo sapiens
587 SMARCD1 6602
Negative Genetic Homo sapiens
588 SAR1A 56681
Negative Genetic Homo sapiens
589 MGA  
Positive Genetic Homo sapiens
590 AIG1  
Negative Genetic Homo sapiens
591 NOC4L 79050
Positive Genetic Homo sapiens
592 NIT1 4817
Negative Genetic Homo sapiens
593 ASPM 259266
Negative Genetic Homo sapiens
594 FOXI1  
Affinity Capture-MS Homo sapiens
595 ENDOD1 23052
Positive Genetic Homo sapiens
596 LRRC20  
Negative Genetic Homo sapiens
597 KARS 3735
Co-fractionation Homo sapiens
598 E2F7  
Negative Genetic Homo sapiens
599 YY1 7528
Positive Genetic Homo sapiens
600 FBXO6 26270
Affinity Capture-MS Homo sapiens
601 ACE2 59272
Affinity Capture-MS Homo sapiens
602 UBE2R2 54926
Positive Genetic Homo sapiens
603 LAMTOR5 10542
Positive Genetic Homo sapiens
604 HNRNPCL2 440563
Cross-Linking-MS (XL-MS) Homo sapiens
605 NR5A2  
Positive Genetic Homo sapiens
606 AP2M1 1173
Affinity Capture-MS Homo sapiens
607 TM9SF3 56889
Negative Genetic Homo sapiens
608 PQLC2  
Negative Genetic Homo sapiens
609 ELK1  
Negative Genetic Homo sapiens
610 GIGYF2 26058
Negative Genetic Homo sapiens
611 INPP5K 51763
Negative Genetic Homo sapiens
612 NRBP1 29959
Positive Genetic Homo sapiens
Negative Genetic Homo sapiens
613 MAU2  
Negative Genetic Homo sapiens
614 LYSMD4 145748
Negative Genetic Homo sapiens
615 PRPF19 27339
Co-fractionation Homo sapiens
616 FLNB 2317
Co-fractionation Homo sapiens
617 MSL1 339287
Negative Genetic Homo sapiens
618 SEC16A 9919
Negative Genetic Homo sapiens
619 ZNF236  
Positive Genetic Homo sapiens
620 MAPKAPK5 8550
Positive Genetic Homo sapiens
621 PIK3CA 5290
Positive Genetic Homo sapiens
622 DLL4  
Positive Genetic Homo sapiens
623 CTR9 9646
Negative Genetic Homo sapiens
624 MATR3 9782
Negative Genetic Homo sapiens
625 HDLBP 3069
Positive Genetic Homo sapiens
626 LRRC41 10489
Positive Genetic Homo sapiens
627 DET1  
Negative Genetic Homo sapiens
628 HSPA9 3313
Co-fractionation Homo sapiens
629 C1orf43 25912
Negative Genetic Homo sapiens
630 ALG9 79796
Negative Genetic Homo sapiens
631 MON2 23041
Negative Genetic Homo sapiens
632 ATIC 471
Positive Genetic Homo sapiens
633 TPM3 7170
Co-fractionation Homo sapiens
634 HIF1A 3091
Affinity Capture-MS Homo sapiens
635 ZNF574  
Positive Genetic Homo sapiens
636 AHSA1 10598
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
637 ITGB5 3693
Positive Genetic Homo sapiens
638 LLGL2 3993
Negative Genetic Homo sapiens
639 HMGB3P1  
Affinity Capture-MS Homo sapiens
640 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
641 ALDH3A2 224
Negative Genetic Homo sapiens
642 MAPKAP1 79109
Positive Genetic Homo sapiens
643 RPS25 6230
Positive Genetic Homo sapiens
644 YTHDF2 51441
Negative Genetic Homo sapiens
645 RAB3GAP2 25782
Negative Genetic Homo sapiens
646 JUP 3728
Affinity Capture-MS Homo sapiens
647 DIAPH3 81624
Positive Genetic Homo sapiens
648 ATL2 64225
Negative Genetic Homo sapiens
649 RNF214  
Positive Genetic Homo sapiens
650 PDHA1 5160
Affinity Capture-MS Homo sapiens
651 LENG8  
Negative Genetic Homo sapiens
652 PBRM1 55193
Positive Genetic Homo sapiens
653 LAMTOR2 28956
Positive Genetic Homo sapiens
654 ASNS 440
Co-fractionation Homo sapiens
655 EDC3 80153
Negative Genetic Homo sapiens
656 RFWD2  
Negative Genetic Homo sapiens
657 REST 5978
Negative Genetic Homo sapiens
658 VDAC2 7417
Negative Genetic Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
659 UFL1 23376
Affinity Capture-MS Homo sapiens
660 PAFAH1B2 5049
Positive Genetic Homo sapiens
661 THRA  
Positive Genetic Homo sapiens
662 SPG11 80208
Positive Genetic Homo sapiens
663 MBNL1 4154
Positive Genetic Homo sapiens
664 CDK13 8621
Positive Genetic Homo sapiens
665 MED12  
Positive Genetic Homo sapiens
666 COA6  
Negative Genetic Homo sapiens
667 FLNA 2316
Co-fractionation Homo sapiens
Negative Genetic Homo sapiens
668 TRAPPC3 27095
Negative Genetic Homo sapiens
669 UBN1  
Negative Genetic Homo sapiens
670 ATP6V1E1 529
Negative Genetic Homo sapiens
671 HNRNPF 3185
Negative Genetic Homo sapiens
672 RPRD1B 58490
Positive Genetic Homo sapiens
673 FOXM1  
Positive Genetic Homo sapiens
674 SERBP1 26135
Affinity Capture-MS Homo sapiens
675 STT3B 201595
Negative Genetic Homo sapiens
676 UBA3 9039
Positive Genetic Homo sapiens
677 RNF219  
Positive Genetic Homo sapiens
678 GPS2  
Negative Genetic Homo sapiens
679 DPH6  
Positive Genetic Homo sapiens
680 ATXN3 4287
Affinity Capture-MS Homo sapiens
681 GTPBP2 54676
Negative Genetic Homo sapiens
682 ZNF408  
Negative Genetic Homo sapiens
683 UBE2V2 7336
Negative Genetic Homo sapiens
684 MFGE8 4240
Negative Genetic Homo sapiens
685 EP300 2033
Negative Genetic Homo sapiens
686 KIAA0922  
Positive Genetic Homo sapiens
687 UBE2H 7328
Affinity Capture-MS Homo sapiens
688 INSIG1  
Affinity Capture-MS Homo sapiens
689 ZNF292  
Positive Genetic Homo sapiens
690 OTUD5 55593
Negative Genetic Homo sapiens
691 MCM8 84515
Negative Genetic Homo sapiens
692 DPYSL2 1808
Co-fractionation Homo sapiens
693 TWIST1  
Positive Genetic Homo sapiens
694 RNASEH2B  
Negative Genetic Homo sapiens
695 KMT2C 58508
Negative Genetic Homo sapiens
696 LGR4 55366
Affinity Capture-MS Homo sapiens
697 QARS 5859
Co-fractionation Homo sapiens
698 ARID5B 84159
Negative Genetic Homo sapiens
699 DERL2 51009
Negative Genetic Homo sapiens
700 PAXIP1  
Negative Genetic Homo sapiens
701 RPS3A 6189
Positive Genetic Homo sapiens
702 PSMD6 9861
Co-fractionation Homo sapiens
703 CETN1  
Positive Genetic Homo sapiens
704 SOX4  
Negative Genetic Homo sapiens
705 GGPS1  
Negative Genetic Homo sapiens
706 TADA3  
Positive Genetic Homo sapiens
707 TLK2  
Negative Genetic Homo sapiens
708 TRUB2  
Negative Genetic Homo sapiens
709 KIAA0020 9933
Positive Genetic Homo sapiens
710 TSG101 7251
Affinity Capture-MS Homo sapiens
711 TAF3 83860
Negative Genetic Homo sapiens
712 USP9X 8239
Negative Genetic Homo sapiens
713 C19orf43  
Positive Genetic Homo sapiens
714 PTP4A1 7803
Positive Genetic Homo sapiens
715 LMBR1  
Negative Genetic Homo sapiens
716 COG2 22796
Negative Genetic Homo sapiens
717 GFI1  
Positive Genetic Homo sapiens
718 HSD17B12 51144
Co-fractionation Homo sapiens
719 SLC22A9  
Negative Genetic Homo sapiens
720 FBXO42  
Negative Genetic Homo sapiens
721 TMPO 7112
Affinity Capture-MS Homo sapiens
722 ILF2 3608