Experiment description of studies that identified HSP90AA4P in sEVs

1 Experiment ID 20 MISEV standards ✔ EM Biophysical techniques ✔ HSP90|CD63|CD81|LAMP1 Enriched markers ✔ GOLGA2|cytochrome c Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 17956143     Organism Homo sapiens Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells. Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS" Journal name JPR Publication year 2007 Sample Colorectal cancer cells Sample name HT29 Isolation/purification methods Differential centrifugation Sucrose density gradient Diafiltration Flotation density 1.16 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [LTQ] Western blotting

2 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for HSP90AA4P

Protein Interactor ExoCarta ID Identification method PubMed Species 1 HIST1H2BC 8347 Cross-Linking-MS (XL-MS) Homo sapiens 2 RPS6KA5 9252 Affinity Capture-MS Homo sapiens 3 CCDC117   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 ANKK1   Affinity Capture-MS Homo sapiens 5 TSSK6 83983 Affinity Capture-MS Homo sapiens 6 ANAPC5 51433 Affinity Capture-MS Homo sapiens 7 DTNA   Affinity Capture-MS Homo sapiens 8 RPS6KA4 8986 Affinity Capture-MS Homo sapiens 9 AKT3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 10 UNC45B   Affinity Capture-MS Homo sapiens 11 AMHR2   Affinity Capture-MS Homo sapiens 12 BTBD1   Affinity Capture-MS Homo sapiens 13 BBS10   Affinity Capture-MS Homo sapiens 14 PLCG2 5336 Affinity Capture-MS Homo sapiens 15 ZNF843   Affinity Capture-MS Homo sapiens 16 SCARA3   Affinity Capture-MS Homo sapiens 17 GTF2E2   Affinity Capture-MS Homo sapiens 18 KIF23 9493 Affinity Capture-MS Homo sapiens 19 YES1 7525 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 IMPDH2 3615 Affinity Capture-MS Homo sapiens 21 TRABD 80305 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 TP53TG5   Affinity Capture-MS Homo sapiens 23 PRC1 9055 Affinity Capture-MS Homo sapiens 24 STIP1 10963 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 SMOC1 64093 Affinity Capture-MS Homo sapiens 26 TATDN1 83940 Co-fractionation Homo sapiens 27 MAP3K6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 PALLD 23022 Co-fractionation Homo sapiens 29 PKN3 29941 Affinity Capture-MS Homo sapiens 30 TFCP2 7024 Affinity Capture-MS Homo sapiens 31 IL17D 53342 Affinity Capture-MS Homo sapiens 32 KIF14 9928 Affinity Capture-MS Homo sapiens 33 CHMP4C 92421 Affinity Capture-MS Homo sapiens 34 TRIM41 90933 Affinity Capture-MS Homo sapiens 35 PNPLA5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 36 RPL9 6133 Co-fractionation Homo sapiens 37 ECT2 1894 Affinity Capture-MS Homo sapiens 38 MOS 4342 Affinity Capture-MS Homo sapiens 39 RBM7   Affinity Capture-MS Homo sapiens 40 PILRB 29990 Affinity Capture-MS Homo sapiens 41 FYN 2534 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 YAP1 10413 Affinity Capture-MS Homo sapiens 43 FAM24B   Affinity Capture-MS Homo sapiens 44 TEAD2   Affinity Capture-MS Homo sapiens 45 TTC9C 283237 Affinity Capture-MS Homo sapiens 46 DZANK1   Affinity Capture-MS Homo sapiens 47 ABHD14A   Affinity Capture-MS Homo sapiens 48 LHFPL5   Affinity Capture-MS Homo sapiens 49 PRKAR1A 5573 Co-fractionation Homo sapiens 50 PRKACB 5567 Affinity Capture-MS Homo sapiens 51 SGK3 23678 Affinity Capture-MS Homo sapiens 52 PRICKLE3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 53 CDK7 1022 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 TMOD4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 SMG8 55181 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 56 NDUFA4L2 56901 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 NT5DC1 221294 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 58 SSX3   Affinity Capture-MS Homo sapiens 59 HSP90AB1 3326 Affinity Capture-MS Homo sapiens 60 LOC254896   Affinity Capture-MS Homo sapiens 61 RIPK4   Affinity Capture-MS Homo sapiens 62 CDKL2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 63 AURKB 9212 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 UBE2D2 7322 Co-fractionation Homo sapiens 65 STK35   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 DND1   Affinity Capture-MS Homo sapiens 67 BAG1 573 Affinity Capture-MS Homo sapiens 68 PSKH2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 ANKS3   Affinity Capture-MS Homo sapiens 70 RPL22 6146 Co-fractionation Homo sapiens 71 FKBP3 2287 Affinity Capture-MS Homo sapiens 72 LHPP 64077 Affinity Capture-MS Homo sapiens 73 WDR47   Affinity Capture-MS Homo sapiens 74 PAFAH1B1 5048 Co-fractionation Homo sapiens 75 ZFAND2A   Affinity Capture-MS Homo sapiens 76 MAP2K2 5605 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 77 AGO1   Affinity Capture-MS Homo sapiens 78 CDC37 11140 Affinity Capture-MS Homo sapiens 79 AURKC   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 FGB 2244 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 81 CDK15   Affinity Capture-MS Homo sapiens 82 ACTR1B 10120 Affinity Capture-MS Homo sapiens 83 PIGK 10026 Affinity Capture-MS Homo sapiens 84 HSP90AA1 3320 Affinity Capture-MS Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 85 CELA3B   Affinity Capture-MS Homo sapiens 86 LATS1   Affinity Capture-MS Homo sapiens 87 SGK2   Affinity Capture-MS Homo sapiens 88 RNPC3   Affinity Capture-MS Homo sapiens 89 CDK13 8621 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 90 SLC48A1 55652 Affinity Capture-MS Homo sapiens 91 KLK10 5655 Affinity Capture-MS Homo sapiens 92 RAPGEF5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 CDK9 1025 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 94 PINK1   Affinity Capture-MS Homo sapiens 95 STK11 6794 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 96 PTGES3 10728 Affinity Capture-MS Homo sapiens 97 SRMS   Affinity Capture-MS Homo sapiens 98 STK32C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 99 CYP3A43   Affinity Capture-MS Homo sapiens View the network

Pathways in which HSP90AA4P is involved

No pathways found