Gene description for CNTNAP4
Gene name contactin associated protein-like 4
Gene symbol CNTNAP4
Other names/aliases CASPR4
Species Homo sapiens
 Database cross references - CNTNAP4
ExoCarta ExoCarta_85445
Entrez Gene 85445
HGNC 18747
MIM 610518
UniProt Q9C0A0  
 CNTNAP4 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for CNTNAP4
Biological Process
    regulation of synaptic transmission, GABAergic GO:0032228 ISS
    regulation of synaptic transmission, dopaminergic GO:0032225 ISS
    cell adhesion GO:0007155 IEA
    regulation of grooming behavior GO:2000821 ISS
Subcellular Localization
    dendrite GO:0030425 IEA
    integral component of membrane GO:0016021 IEA
    cell junction GO:0030054 IEA
    presynaptic membrane GO:0042734 ISS
 Experiment description of studies that identified CNTNAP4 in exosomes
Experiment ID 274
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
 Protein-protein interactions for CNTNAP4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APBA1  
Reconstituted Complex Homo sapiens
2 CASK 8573
Reconstituted Complex Homo sapiens
View the network image/svg+xml
 Pathways in which CNTNAP4 is involved
No pathways found

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