Gene description for DNAJA2
Gene name DnaJ (Hsp40) homolog, subfamily A, member 2
Gene symbol DNAJA2
Other names/aliases CPR3
DJ3
DJA2
DNAJ
DNJ3
HIRIP4
PRO3015
RDJ2
Species Homo sapiens
 Database cross references - DNAJA2
ExoCarta ExoCarta_10294
Vesiclepedia VP_10294
Entrez Gene 10294
HGNC 14884
MIM 611322
UniProt O60884  
 DNAJA2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
Urine 19056867    
 Gene ontology annotations for DNAJA2
Molecular Function
    ATPase activator activity GO:0001671 IDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    Hsp70 protein binding GO:0030544 IEA
    metal ion binding GO:0046872 IEA
    unfolded protein binding GO:0051082 IDA
    protein-folding chaperone binding GO:0051087 IBA
    protein-folding chaperone binding GO:0051087 IPI
Biological Process
    positive regulation of cell population proliferation GO:0008284 TAS
    response to heat GO:0009408 IEA
    protein refolding GO:0042026 IBA
    protein refolding GO:0042026 IDA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    membrane GO:0016020 IEA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified DNAJA2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
15
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
25
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
26
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
31
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
34
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
36
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
37
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
41
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
47
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
48
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
49
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
50
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
51
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
53
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
54
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for DNAJA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 WDR6 11180
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 EIF2AK4 440275
Affinity Capture-MS Homo sapiens
3 DNAJC11 55735
Affinity Capture-MS Homo sapiens
4 NPRL2  
Affinity Capture-MS Homo sapiens
5 SHC1 6464
Affinity Capture-MS Homo sapiens
6 LLGL1 3996
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 RIN3  
Affinity Capture-MS Homo sapiens
8 DYNC1I2 1781
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
9 GAK 2580
Affinity Capture-MS Homo sapiens
10 TUBB8 347688
Affinity Capture-MS Homo sapiens
11 PISD  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 KIF20A 10112
Affinity Capture-MS Homo sapiens
13 BRD2  
Affinity Capture-MS Homo sapiens
14 UBC 7316
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
15 VHL  
Affinity Capture-MS Homo sapiens
16 SOX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SEPT9 10801
Proximity Label-MS Homo sapiens
18 WDR62  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 KBTBD6  
Affinity Capture-MS Homo sapiens
20 MLLT11  
Affinity Capture-MS Homo sapiens
21 WDR76  
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
22 IARS2 55699
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
23 ACTR3 10096
Proximity Label-MS Homo sapiens
24 GNS 2799
Co-fractionation Homo sapiens
25 GDI1 2664
Affinity Capture-MS Homo sapiens
26 PUSL1  
Affinity Capture-MS Homo sapiens
27 HSPH1 10808
Co-fractionation Homo sapiens
28 POU5F1  
Affinity Capture-MS Homo sapiens
29 ETFA 2108
Proximity Label-MS Homo sapiens
30 DNAJB1 3337
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
31 FAM210A  
Affinity Capture-MS Homo sapiens
32 LOC81691 81691
Affinity Capture-MS Homo sapiens
33 POLR2C 5432
Proximity Label-MS Homo sapiens
34 METTL23  
Affinity Capture-MS Homo sapiens
35 KIF14 9928
Affinity Capture-MS Homo sapiens
36 BACH1 571
Proximity Label-MS Homo sapiens
37 NOTCH2 4853
Proximity Label-MS Homo sapiens
38 KLF16  
Affinity Capture-MS Homo sapiens
39 BAG5 9529
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 TCP1 6950
Co-fractionation Homo sapiens
41 KIAA1147  
Affinity Capture-MS Homo sapiens
42 HPS5 11234
Affinity Capture-MS Homo sapiens
43 MTMR11  
Affinity Capture-MS Homo sapiens
44 SHMT1 6470
Proximity Label-MS Homo sapiens
45 BCAS3 54828
Affinity Capture-MS Homo sapiens
46 COPB1 1315
Co-fractionation Homo sapiens
47 Syce2  
Affinity Capture-MS Mus musculus
48 ESRRB  
Affinity Capture-MS Homo sapiens
49 NUDC 10726
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 MYH9 4627
Co-fractionation Homo sapiens
51 OGT 8473
Reconstituted Complex Homo sapiens
52 GTF3C2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 NOS2  
Affinity Capture-MS Homo sapiens
54 ASCC2 84164
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 FNBP1 23048
Co-fractionation Homo sapiens
56 PRKDC 5591
Co-fractionation Homo sapiens
57 PIGS 94005
Affinity Capture-MS Homo sapiens
58 HECTD1 25831
Affinity Capture-MS Homo sapiens
59 TRMT2A 27037
Affinity Capture-MS Homo sapiens
60 STUB1 10273
Affinity Capture-MS Homo sapiens
61 SQRDL 58472
Affinity Capture-MS Homo sapiens
62 ANLN 54443
Affinity Capture-MS Homo sapiens
63 DTL  
Affinity Capture-MS Homo sapiens
64 RPS19 6223
Co-fractionation Homo sapiens
65 QSOX1 5768
Affinity Capture-MS Homo sapiens
66 HBS1L 10767
Affinity Capture-MS Homo sapiens
67 EPAS1  
Affinity Capture-MS Homo sapiens
68 NEK4  
Affinity Capture-MS Homo sapiens
69 MAP4K4 9448
Affinity Capture-MS Homo sapiens
70 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 DIP2A 23181
Affinity Capture-MS Homo sapiens
72 FKBP8 23770
Affinity Capture-MS Homo sapiens
73 TTF2 8458
Affinity Capture-MS Homo sapiens
74 DUSP16  
Affinity Capture-MS Homo sapiens
75 RBBP4 5928
Co-fractionation Homo sapiens
76 TUBA4A 7277
Affinity Capture-MS Homo sapiens
77 PRMT5 10419
Co-fractionation Homo sapiens
78 FAM120B 84498
Affinity Capture-MS Homo sapiens
79 PI4K2B 55300
Affinity Capture-MS Homo sapiens
80 LUC7L2 51631
Co-fractionation Homo sapiens
81 C4orf29 80167
Affinity Capture-MS Homo sapiens
82 WDR60 55112
Affinity Capture-MS Homo sapiens
83 LTV1  
Proximity Label-MS Homo sapiens
84 AHR 196
Affinity Capture-MS Homo sapiens
85 SHKBP1  
Affinity Capture-MS Homo sapiens
86 HSPA1A 3303
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
87 HSPA4 3308
Co-fractionation Homo sapiens
88 RFWD3  
Affinity Capture-MS Homo sapiens
89 DTWD2  
Affinity Capture-MS Homo sapiens
90 ILK 3611
Affinity Capture-MS Homo sapiens
91 KRT19 3880
Proximity Label-MS Homo sapiens
92 CXorf57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 SACS 26278
Proximity Label-MS Homo sapiens
94 DENND6A 201627
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 Tubg1 103733
Affinity Capture-MS Mus musculus
96 Tubb5 22154
Affinity Capture-MS Mus musculus
97 RHOBTB3 22836
Affinity Capture-MS Homo sapiens
98 MKS1 54903
Affinity Capture-MS Homo sapiens
99 URGCP 55665
Affinity Capture-MS Homo sapiens
100 MTA1 9112
Co-fractionation Homo sapiens
101 DYRK3  
Two-hybrid Homo sapiens
102 TUBGCP3 10426
Proximity Label-MS Homo sapiens
103 LCK 3932
Proximity Label-MS Homo sapiens
104 WRAP53  
Affinity Capture-MS Homo sapiens
105 DCTN2 10540
Proximity Label-MS Homo sapiens
106 TBL3 10607
Affinity Capture-MS Homo sapiens
107 NUDT19 390916
Proximity Label-MS Homo sapiens
108 TARS 6897
Proximity Label-MS Homo sapiens
109 PSMA1 5682
Co-fractionation Homo sapiens
110 Tuba3a 22144
Affinity Capture-MS Mus musculus
111 ERCC3  
Affinity Capture-MS Homo sapiens
112 WWP2 11060
Affinity Capture-MS Homo sapiens
113 DDX11 1663
Affinity Capture-MS Homo sapiens
114 PSMA5 5686
Affinity Capture-MS Homo sapiens
115 SLC25A51  
Proximity Label-MS Homo sapiens
116 CLTA 1211
Proximity Label-MS Homo sapiens
117 ACSF3 197322
Affinity Capture-MS Homo sapiens
118 FBXW9  
Affinity Capture-MS Homo sapiens
119 POLG  
Affinity Capture-MS Homo sapiens
120 PSMC4 5704
Co-fractionation Homo sapiens
121 IFIT2 3433
Affinity Capture-MS Homo sapiens
122 EDRF1  
Proximity Label-MS Homo sapiens
123 DERL1 79139
Proximity Label-MS Homo sapiens
124 PSMA6 5687
Co-fractionation Homo sapiens
125 SMC3 9126
Co-fractionation Homo sapiens
126 KIF23 9493
Affinity Capture-MS Homo sapiens
127 SPRTN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 CLIP1 6249
Proximity Label-MS Homo sapiens
129 HSPA6 3310
Affinity Capture-Western Homo sapiens
130 GJA1 2697
Proximity Label-MS Homo sapiens
131 BTF3 689
Affinity Capture-MS Homo sapiens
132 HSPA12B 116835
Affinity Capture-MS Homo sapiens
133 STRN3 29966
Affinity Capture-MS Homo sapiens
134 GEMIN8 54960
Proximity Label-MS Homo sapiens
135 HSP90AB1 3326
Co-fractionation Homo sapiens
136 ASXL1  
Affinity Capture-MS Homo sapiens
137 SAFB 6294
Co-fractionation Homo sapiens
138 B3GNT2 10678
Affinity Capture-MS Homo sapiens
139 HSPA2 3306
Affinity Capture-MS Homo sapiens
140 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
141 DHX35  
Affinity Capture-MS Homo sapiens
142 ERGIC1 57222
Proximity Label-MS Homo sapiens
143 OBSL1 23363
Proximity Label-MS Homo sapiens
144 STIP1 10963
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
145 DNAJC7 7266
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
146 C5orf34  
Affinity Capture-MS Homo sapiens
147 TTLL5  
Affinity Capture-MS Homo sapiens
148 PRNP 5621
Affinity Capture-MS Homo sapiens
149 AGBL5  
Affinity Capture-MS Homo sapiens
150 POP1 10940
Co-fractionation Homo sapiens
151 EML5 161436
Affinity Capture-MS Homo sapiens
152 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
153 CEP55 55165
Proximity Label-MS Homo sapiens
154 RNASEH2A 10535
Affinity Capture-MS Homo sapiens
155 EIF2A 83939
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 WRAP73 49856
Affinity Capture-MS Homo sapiens
157 EXOC4 60412
Affinity Capture-MS Homo sapiens
158 TFDP1  
Proximity Label-MS Homo sapiens
159 TUBA1C 84790
Affinity Capture-MS Homo sapiens
160 ALDH3B1 221
Affinity Capture-MS Homo sapiens
161 DCAF10  
Affinity Capture-MS Homo sapiens
162 IFT172 26160
Affinity Capture-MS Homo sapiens
163 CDC42EP1 11135
Affinity Capture-MS Homo sapiens
164 AGPS 8540
Proximity Label-MS Homo sapiens
165 KCTD3  
Affinity Capture-MS Homo sapiens
166 Ksr1  
Affinity Capture-MS Mus musculus
167 CYLD  
Affinity Capture-MS Homo sapiens
168 ATG16L1 55054
Affinity Capture-MS Homo sapiens
169 AIFM1 9131
Proximity Label-MS Homo sapiens
170 SMARCAD1  
Affinity Capture-MS Homo sapiens
171 XPO1 7514
Co-fractionation Homo sapiens
172 USP15 9958
Co-fractionation Homo sapiens
173 RC3H2  
Affinity Capture-MS Homo sapiens
174 MTX2 10651
Proximity Label-MS Homo sapiens
175 UBE2L6 9246
Affinity Capture-MS Homo sapiens
176 TAF1B  
Affinity Capture-MS Homo sapiens
177 ELP3 55140
Affinity Capture-MS Homo sapiens
178 TUBB4B 10383
Co-fractionation Homo sapiens
179 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
180 NUP43 348995
Proximity Label-MS Homo sapiens
181 RIPK4  
Affinity Capture-MS Homo sapiens
182 PM20D2 135293
Proximity Label-MS Homo sapiens
183 CNR2  
Affinity Capture-MS Homo sapiens
184 NLRP3  
Affinity Capture-MS Homo sapiens
185 SAP25  
Affinity Capture-MS Homo sapiens
186 DDRGK1 65992
Affinity Capture-MS Homo sapiens
187 XRCC3  
Affinity Capture-MS Homo sapiens
188 CBWD1 55871
Affinity Capture-MS Homo sapiens
189 BRD9 65980
Affinity Capture-MS Homo sapiens
190 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 TRAF7  
Affinity Capture-MS Homo sapiens
192 SLC25A16  
Affinity Capture-MS Homo sapiens
193 TERF2  
Affinity Capture-MS Homo sapiens
194 PARP1 142
Proximity Label-MS Homo sapiens
195 WDR19 57728
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 KLHL26  
Affinity Capture-MS Homo sapiens
198 SQSTM1 8878
Proximity Label-MS Homo sapiens
199 KLHL11  
Affinity Capture-MS Homo sapiens
200 AGO4  
Affinity Capture-MS Homo sapiens
201 ESR1  
Affinity Capture-MS Homo sapiens
202 EEF1A1P5 158078
Cross-Linking-MS (XL-MS) Homo sapiens
203 C16orf72 29035
Affinity Capture-MS Homo sapiens
204 BLVRA 644
Affinity Capture-MS Homo sapiens
205 C2CD5 9847
Proximity Label-MS Homo sapiens
206 HSPA4L 22824
Co-fractionation Homo sapiens
207 SMARCAL1  
Affinity Capture-MS Homo sapiens
208 DCAF4  
Affinity Capture-MS Homo sapiens
209 NEK9 91754
Affinity Capture-MS Homo sapiens
210 MYC  
Affinity Capture-MS Homo sapiens
211 IRS4 8471
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
212 PRMT1 3276
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
213 C17orf59 54785
Proximity Label-MS Homo sapiens
214 MTCH2 23788
Proximity Label-MS Homo sapiens
215 DPP9 91039
Proximity Label-MS Homo sapiens
216 MTCH1 23787
Proximity Label-MS Homo sapiens
217 KSR1  
Affinity Capture-MS Homo sapiens
218 EML4 27436
Co-fractionation Homo sapiens
219 BBS7 55212
Proximity Label-MS Homo sapiens
220 DNAJA4 55466
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 IRAK1  
Affinity Capture-MS Homo sapiens
222 FANCB  
Affinity Capture-MS Homo sapiens
223 NEFM 4741
Affinity Capture-MS Homo sapiens
224 RPS6KB2  
Affinity Capture-MS Homo sapiens
225 Tubb4b 227613
Affinity Capture-MS Mus musculus
226 LRPPRC 10128
Co-fractionation Homo sapiens
227 CAPZB 832
Affinity Capture-MS Homo sapiens
228 RUVBL1 8607
Co-fractionation Homo sapiens
229 Tgs1  
Affinity Capture-MS Mus musculus
230 CRYZ 1429
Proximity Label-MS Homo sapiens
231 MCM2 4171
Affinity Capture-MS Homo sapiens
232 FAM98A 25940
Proximity Label-MS Homo sapiens
233 COPE 11316
Affinity Capture-MS Homo sapiens
234 ZNF460  
Affinity Capture-MS Homo sapiens
235 PLD2 5338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 PGD 5226
Proximity Label-MS Homo sapiens
237 ESPL1  
Proximity Label-MS Homo sapiens
238 EML3 256364
Affinity Capture-MS Homo sapiens
239 N4BP2  
Proximity Label-MS Homo sapiens
240 EHD1 10938
Affinity Capture-MS Homo sapiens
241 HSPA8 3312
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
242 LCMT2 9836
Affinity Capture-MS Homo sapiens
243 NF2 4771
Affinity Capture-MS Homo sapiens
244 DLD 1738
Affinity Capture-MS Homo sapiens
245 MTMR8  
Affinity Capture-MS Homo sapiens
246 SAMM50 25813
Proximity Label-MS Homo sapiens
247 PRPH 5630
Proximity Label-MS Homo sapiens
248 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 MTO1  
Affinity Capture-MS Homo sapiens
250 CXADR 1525
Proximity Label-MS Homo sapiens
251 CHCHD3 54927
Proximity Label-MS Homo sapiens
252 DNAJC5 80331
Affinity Capture-MS Homo sapiens
253 ABCF2 10061
Co-fractionation Homo sapiens
254 LRWD1  
Affinity Capture-MS Homo sapiens
255 CHMP4B 128866
Affinity Capture-MS Homo sapiens
256 Ten1  
Affinity Capture-MS Mus musculus
257 TRMT11 60487
Affinity Capture-MS Homo sapiens
258 NTRK1 4914
Affinity Capture-MS Homo sapiens
259 ARNT 405
Affinity Capture-MS Homo sapiens
260 ZNF131  
Affinity Capture-MS Homo sapiens
261 DNAJA1 3301
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
262 SMAD2 4087
Affinity Capture-MS Homo sapiens
263 TUBA1B 10376
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
264 NARS2  
Affinity Capture-MS Homo sapiens
265 PIK3C2A 5286
Proximity Label-MS Homo sapiens
266 ENDOG  
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 HSPA1L 3305
Affinity Capture-MS Homo sapiens
268 CWF19L1 55280
Affinity Capture-MS Homo sapiens
269 SLC25A12 8604
Affinity Capture-MS Homo sapiens
270 METTL14  
Affinity Capture-MS Homo sapiens
271 BAG2 9532
Affinity Capture-MS Homo sapiens
272 ECT2 1894
Affinity Capture-MS Homo sapiens
273 ASCC1 51008
Proximity Label-MS Homo sapiens
274 OCRL 4952
Affinity Capture-MS Homo sapiens
275 HSD3B7 80270
Proximity Label-MS Homo sapiens
276 NR3C1 2908
Proximity Label-MS Homo sapiens
277 DCAF13 25879
Affinity Capture-MS Homo sapiens
278 DDB2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
279 FBXO6 26270
Affinity Capture-MS Homo sapiens
280 METTL21B  
Affinity Capture-MS Homo sapiens
281 C17orf80 55028
Affinity Capture-MS Homo sapiens
282 TANGO6 79613
Affinity Capture-MS Homo sapiens
283 APEH 327
Proximity Label-MS Homo sapiens
284 ZNFX1 57169
Affinity Capture-MS Homo sapiens
285 DNAJC3 5611
Affinity Capture-MS Homo sapiens
286 FLII 2314
Co-fractionation Homo sapiens
287 RNF2  
Affinity Capture-MS Homo sapiens
288 SENP5  
Affinity Capture-MS Homo sapiens
289 HAX1  
Proximity Label-MS Homo sapiens
290 HSPA9 3313
Co-fractionation Homo sapiens
291 TSR1 55720
Co-fractionation Homo sapiens
292 ARAF 369
Affinity Capture-MS Homo sapiens
293 SLC25A30 253512
Affinity Capture-MS Homo sapiens
294 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
295 FLOT1 10211
Proximity Label-MS Homo sapiens
296 ACBD5 91452
Proximity Label-MS Homo sapiens
297 HIF1A 3091
Affinity Capture-MS Homo sapiens
298 PIP5K1A 8394
Affinity Capture-MS Homo sapiens
299 TUBB2A 7280
Affinity Capture-MS Homo sapiens
300 LLGL2 3993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
302 ALDH3A2 224
Proximity Label-MS Homo sapiens
303 CDC20 991
Affinity Capture-MS Homo sapiens
304 HMGB1 3146
Co-fractionation Homo sapiens
305 FBXL6  
Affinity Capture-MS Homo sapiens
306 THUMPD3 25917
Affinity Capture-MS Homo sapiens
307 L3MBTL2  
Proximity Label-MS Homo sapiens
308 CDC40  
Affinity Capture-MS Homo sapiens
309 DNA2  
Affinity Capture-MS Homo sapiens
310 PDHA1 5160
Affinity Capture-MS Homo sapiens
311 POP4 10775
Affinity Capture-MS Homo sapiens
312 TUBB3 10381
Affinity Capture-MS Homo sapiens
313 SEPT10 151011
Proximity Label-MS Homo sapiens
314 PBRM1 55193
Co-fractionation Homo sapiens
315 ASNS 440
Affinity Capture-MS Homo sapiens
316 PJA2  
Proximity Label-MS Homo sapiens
317 TMLHE 55217
Affinity Capture-MS Homo sapiens
318 C11orf52 91894
Proximity Label-MS Homo sapiens
319 MKI67  
Affinity Capture-MS Homo sapiens
320 TUBB6 84617
Affinity Capture-MS Homo sapiens
321 UFL1 23376
Affinity Capture-MS Homo sapiens
322 NEDD1 121441
Affinity Capture-MS Homo sapiens
323 METTL3  
Affinity Capture-MS Homo sapiens
324 TAF1C  
Affinity Capture-MS Homo sapiens
325 ERG  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
326 RC3H1 149041
Affinity Capture-MS Homo sapiens
327 UBA6 55236
Proximity Label-MS Homo sapiens
328 NOL9 79707
Affinity Capture-MS Homo sapiens
329 CCRN4L  
Affinity Capture-MS Homo sapiens
330 CTSH 1512
Affinity Capture-MS Homo sapiens
331 UBE2H 7328
Affinity Capture-MS Homo sapiens
332 ACTR2 10097
Proximity Label-MS Homo sapiens
333 RPS3A 6189
Co-fractionation Homo sapiens
334 TNPO1 3842
Co-fractionation Homo sapiens
335 PSMD11 5717
Co-fractionation Homo sapiens
336 IFT122 55764
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
337 CCT4 10575
Co-fractionation Homo sapiens
338 TROVE2 6738
Co-fractionation Homo sapiens
339 WDR36 134430
Affinity Capture-MS Homo sapiens
340 HSPA5 3309
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
341 USP36  
Affinity Capture-MS Homo sapiens
342 KIAA1429 25962
Affinity Capture-MS Homo sapiens
343 PPP1R12A 4659
Co-fractionation Homo sapiens
344 TGFB1 7040
Affinity Capture-MS Homo sapiens
345 ZRANB3  
Affinity Capture-MS Homo sapiens
346 COPS5 10987
Affinity Capture-MS Homo sapiens
347 FBXW7  
Affinity Capture-MS Homo sapiens
348 SURF1  
Proximity Label-MS Homo sapiens
349 FAM135A  
Proximity Label-MS Homo sapiens
350 ASH2L 9070
Proximity Label-MS Homo sapiens
351 WDR45  
Affinity Capture-MS Homo sapiens
352 ADSS 159
Affinity Capture-MS Homo sapiens
353 FBXW5  
Affinity Capture-MS Homo sapiens
354 LAMTOR1 55004
Proximity Label-MS Homo sapiens
355 RB1 5925
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
356 GEMIN5 25929
Affinity Capture-MS Homo sapiens
357 POLD1 5424
Affinity Capture-MS Homo sapiens
358 SMARCA5 8467
Co-fractionation Homo sapiens
359 SFXN3 81855
Affinity Capture-MS Homo sapiens
360 VCP 7415
Affinity Capture-MS Homo sapiens
361 ATXN3 4287
Affinity Capture-MS Homo sapiens
362 SMAD3 4088
Affinity Capture-MS Homo sapiens
363 TARS2 80222
Proximity Label-MS Homo sapiens
364 DCTN1 1639
Co-fractionation Homo sapiens
365 HJURP  
Affinity Capture-MS Homo sapiens
366 PCSK9 255738
Affinity Capture-MS Homo sapiens
367 MYH10 4628
Co-fractionation Homo sapiens
368 RHOT2 89941
Proximity Label-MS Homo sapiens
369 BAG3 9531
Affinity Capture-MS Homo sapiens
370 ASCC3 10973
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
371 RPL23 9349
Affinity Capture-MS Homo sapiens
372 CTC1  
Affinity Capture-MS Homo sapiens
373 PANX1 24145
Proximity Label-MS Homo sapiens
374 GREB1 9687
Affinity Capture-MS Homo sapiens
375 ARF6 382
Proximity Label-MS Homo sapiens
376 VARS 7407
Co-fractionation Homo sapiens
377 ELP2 55250
Affinity Capture-MS Homo sapiens
378 MSTO1 55154
Affinity Capture-MS Homo sapiens
379 FDFT1 2222
Affinity Capture-MS Homo sapiens
380 AURKB 9212
Affinity Capture-MS Homo sapiens
381 MAPK6  
Affinity Capture-MS Homo sapiens
382 DNAJC24  
Affinity Capture-MS Homo sapiens
383 N4BP2L2 10443
Affinity Capture-MS Homo sapiens
384 DHX34 9704
Affinity Capture-MS Homo sapiens
385 CDC45  
Affinity Capture-MS Homo sapiens
386 Cxxc1  
Affinity Capture-MS Mus musculus
387 PRR14L 253143
Affinity Capture-MS Homo sapiens
388 PRKD2 25865
Affinity Capture-MS Homo sapiens
389 KLHL8  
Affinity Capture-MS Homo sapiens
390 SMARCC1 6599
Co-fractionation Homo sapiens
391 LIMK2 3985
Affinity Capture-MS Homo sapiens
392 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
393 HDAC1 3065
Co-fractionation Homo sapiens
394 TUBB1 81027
Affinity Capture-MS Homo sapiens
395 SFXN1 94081
Proximity Label-MS Homo sapiens
396 ANAPC2 29882
Proximity Label-MS Homo sapiens
397 MAGED1 9500
Proximity Label-MS Homo sapiens
398 CAD 790
Co-fractionation Homo sapiens
399 TRIP4 9325
Proximity Label-MS Homo sapiens
400 UPF1 5976
Proximity Label-MS Homo sapiens
401 TCAF1 9747
Affinity Capture-MS Homo sapiens
402 WDR59 79726
Affinity Capture-MS Homo sapiens
403 XRCC6 2547
Proximity Label-MS Homo sapiens
404 HIRA  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
405 C9orf72  
Affinity Capture-MS Homo sapiens
406 ARHGAP35 2909
Affinity Capture-MS Homo sapiens
407 PTPN18 26469
Affinity Capture-MS Homo sapiens
408 HECW2  
Affinity Capture-MS Homo sapiens
409 NEDD8 4738
Reconstituted Complex Homo sapiens
410 RBBP7 5931
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here