Gene description for HSP90AA2P
Gene name heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene
Gene symbol HSP90AA2P
Other names/aliases HSP90AA2
HSP90ALPHA
HSPCA
HSPCAL3
Species Homo sapiens
 Database cross references - HSP90AA2P
ExoCarta ExoCarta_3324
Entrez Gene 3324
HGNC 5256
MIM 140575
 HSP90AA2P identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells 17956143    
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for HSP90AA2P
Molecular Function
    ATP binding GO:0005524 IEA
    unfolded protein binding GO:0051082 IEA
    molecular_function GO:0003674 ND
Biological Process
    biological_process GO:0008150 ND
    response to stress GO:0006950 IEA
    protein folding GO:0006457 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified HSP90AA2P in exosomes
1
Experiment ID 20
ISEV standards
EM
EV Biophysical techniques
HSP90
EV Cytosolic markers
CD63|CD81|LAMP1
EV Membrane markers
GOLGA2|cytochrome c
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
2
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for HSP90AA2P
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TBK1 29110
Affinity Capture-MS Homo sapiens
2 MAP3K3  
Affinity Capture-MS Homo sapiens
3 IKBKE  
Affinity Capture-MS Homo sapiens
4 IKBKG 8517
Affinity Capture-MS Homo sapiens
5 MAP3K1 4214
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which HSP90AA2P is involved
No pathways found





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