Gene description for XPO1
Gene name	exportin 1
Gene symbol	XPO1
Other names/aliases	CRM1 emb exp1
Species	Homo sapiens
Database cross references - XPO1
ExoCarta	ExoCarta_7514
Entrez Gene	7514
HGNC	12825
MIM	602559
UniProt	O14980
XPO1 identified in exosomes derived from the following tissue/cell type
Bladder cancer cells	20224111
Neuroblastoma cells	25944692
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Thymus	23844026

Gene ontology annotations for XPO1

Molecular Function     transporter activity GO:0005215 TAS     Ran GTPase binding GO:0008536 IEA     protein transporter activity GO:0008565 IEA     protein domain specific binding GO:0019904 IEA     nucleocytoplasmic transporter activity GO:0005487 IMP     RNA binding GO:0003723 IEA     protein binding GO:0005515 IPI Biological Process     mRNA transport GO:0051028 IEA     mitotic cell cycle GO:0000278 TAS     viral life cycle GO:0019058 TAS     response to drug GO:0042493 IEA     ribosomal small subunit export from nucleus GO:0000056 IMP     intracellular transport of virus GO:0075733 TAS     small GTPase mediated signal transduction GO:0007264 TAS     negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 TAS     gene expression GO:0010467 TAS     transforming growth factor beta receptor signaling pathway GO:0007179 TAS     protein localization to nucleus GO:0034504 IEA     regulation of protein catabolic process GO:0042176 IEA     protein export from nucleus GO:0006611 IMP     negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA     ribosomal large subunit export from nucleus GO:0000055 IMP     viral process GO:0016032 TAS     regulation of protein export from nucleus GO:0046825 IEA     regulation of centrosome duplication GO:0010824 IEA Subcellular Localization     nucleoplasm GO:0005654 TAS     nuclear envelope GO:0005635 TAS     kinetochore GO:0000776 IDA     Cajal body GO:0015030 IEA     nuclear membrane GO:0031965 IDA     ribonucleoprotein complex GO:0030529 IDA     cytosol GO:0005829 TAS     membrane GO:0016020 IDA     nucleolus GO:0005730 IEA     nucleus GO:0005634 IDA     annulate lamellae GO:0005642 IDA     intracellular membrane-bounded organelle GO:0043231 IDA     cytoplasm GO:0005737 IDA