Gene description for SYNCRIP
Gene name synaptotagmin binding, cytoplasmic RNA interacting protein
Gene symbol SYNCRIP
Other names/aliases GRY-RBP
GRYRBP
HNRNPQ
HNRPQ1
NSAP1
PP68
hnRNP-Q
Species Homo sapiens
 Database cross references - SYNCRIP
ExoCarta ExoCarta_10492
Vesiclepedia VP_10492
Entrez Gene 10492
HGNC 16918
UniProt O60506  
 SYNCRIP identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for SYNCRIP
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    mRNA 5'-UTR binding GO:0048027 IBA
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IC
    osteoblast differentiation GO:0001649 HDA
    RNA processing GO:0006396 TAS
    RNA splicing GO:0008380 TAS
    mRNA modification GO:0016556 IDA
    negative regulation of translation GO:0017148 IDA
    negative regulation of translation GO:0017148 IMP
    CRD-mediated mRNA stabilization GO:0070934 IBA
    CRD-mediated mRNA stabilization GO:0070934 IDA
    CRD-mediated mRNA stabilization GO:0070934 IMP
    cellular response to type II interferon GO:0071346 IDA
    chromosomal 5-methylcytosine DNA demethylation pathway GO:0141166 NAS
    negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900152 IDA
    negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:2000623 IDA
    positive regulation of cytoplasmic translation GO:2000767 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IEA
    endoplasmic reticulum GO:0005783 IEA
    cytosol GO:0005829 IDA
    membrane GO:0016020 HDA
    mRNA editing complex GO:0045293 NAS
    CRD-mediated mRNA stability complex GO:0070937 IBA
    CRD-mediated mRNA stability complex GO:0070937 IDA
    CRD-mediated mRNA stability complex GO:0070937 IPI
    catalytic step 2 spliceosome GO:0071013 IDA
    histone pre-mRNA 3'end processing complex GO:0071204 ISS
    GAIT complex GO:0097452 IDA
    mCRD-mediated mRNA stability complex GO:0106002 IPI
    ribonucleoprotein complex GO:1990904 IBA
    ribonucleoprotein complex GO:1990904 IDA
 Experiment description of studies that identified SYNCRIP in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
15
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
23
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
30
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
31
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
34
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
41
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
42
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
43
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
44
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
45
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
46
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SYNCRIP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 WDR91 29062
Affinity Capture-MS Homo sapiens
2 HDAC4  
Affinity Capture-MS Homo sapiens
3 UBL4A 8266
Affinity Capture-MS Homo sapiens
4 MRPL33  
Affinity Capture-MS Homo sapiens
5 CEP55 55165
Affinity Capture-MS Homo sapiens
6 Nfyc 18046
Affinity Capture-MS Mus musculus
7 CAP1 10487
Co-fractionation Homo sapiens
8 DDX17 10521
Co-fractionation Homo sapiens
9 EBNA-LP  
Affinity Capture-MS
10 MED13L 23389
Affinity Capture-MS Homo sapiens
11 KIF20A 10112
Affinity Capture-MS Homo sapiens
12 UBC 7316
Affinity Capture-MS Homo sapiens
13 SYT4  
Reconstituted Complex Homo sapiens
14 PRPF40A 55660
Affinity Capture-MS Homo sapiens
15 UTP3 57050
Affinity Capture-MS Homo sapiens
16 WDR76  
Affinity Capture-MS Homo sapiens
17 DARS 1615
Co-fractionation Homo sapiens
18 KIF23 9493
Affinity Capture-MS Homo sapiens
19 APBB2  
Affinity Capture-MS Homo sapiens
20 TRIOBP 11078
Affinity Capture-MS Homo sapiens
21 METAP2 10988
Affinity Capture-MS Homo sapiens
22 AI837181  
Affinity Capture-MS Mus musculus
23 FBL 2091
Proximity Label-MS Homo sapiens
24 RPS9 6203
Co-fractionation Homo sapiens
25 GSPT1 2935
Affinity Capture-MS Homo sapiens
26 ZBTB14  
Affinity Capture-MS Homo sapiens
27 ZNF598 90850
Co-fractionation Homo sapiens
28 MECP2 4204
Affinity Capture-MS Homo sapiens
29 ARIH2 10425
Affinity Capture-MS Homo sapiens
30 FAM120A 23196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 RBM14 10432
Affinity Capture-MS Homo sapiens
32 KIF14 9928
Affinity Capture-MS Homo sapiens
33 AGO2 27161
Co-fractionation Homo sapiens
34 KLF16  
Affinity Capture-MS Homo sapiens
35 CHMP4C 92421
Affinity Capture-MS Homo sapiens
36 CRY1  
Affinity Capture-MS Homo sapiens
37 TMEM177  
Co-fractionation Homo sapiens
38 MEPCE 56257
Affinity Capture-MS Homo sapiens
39 SRSF3 6428
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
40 YBX2 51087
Affinity Capture-MS Homo sapiens
41 TUFM 7284
Proximity Label-MS Homo sapiens
42 PURG  
Affinity Capture-MS Homo sapiens
43 SLC25A20 788
Affinity Capture-MS Homo sapiens
44 PABPC1 26986
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
45 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 ACTN4 81
Co-fractionation Homo sapiens
47 OGT 8473
Reconstituted Complex Homo sapiens
48 MAEL  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
49 HECTD1 25831
Affinity Capture-MS Homo sapiens
50 CUL2 8453
Affinity Capture-MS Homo sapiens
51 CAPN1 823
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
52 TRIM63  
Two-hybrid Homo sapiens
53 SCARNA22  
Affinity Capture-RNA Homo sapiens
54 ANLN 54443
Affinity Capture-MS Homo sapiens
55 RBM39 9584
Affinity Capture-MS Homo sapiens
56 WBSCR16  
Co-fractionation Homo sapiens
57 ELMO3 79767
Affinity Capture-MS Homo sapiens
58 TARBP1 6894
Affinity Capture-MS Homo sapiens
59 LRRC59 55379
Cross-Linking-MS (XL-MS) Homo sapiens
60 NSMCE2  
Affinity Capture-MS Homo sapiens
61 SIRT7  
Affinity Capture-MS Homo sapiens
62 TBC1D10B 26000
Affinity Capture-MS Homo sapiens
63 PRMT8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
64 CD274 29126
Affinity Capture-MS Homo sapiens
65 TNFRSF1A 7132
Affinity Capture-MS Homo sapiens
66 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
67 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
68 EPRS 2058
Co-fractionation Homo sapiens
69 SDC2 6383
Affinity Capture-MS Homo sapiens
70 SS18  
Affinity Capture-MS Homo sapiens
71 HEXA 3073
Affinity Capture-MS Homo sapiens
72 PCBP1 5093
Affinity Capture-MS Homo sapiens
73 RPA3 6119
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
74 UHRF1BP1 54887
Affinity Capture-MS Homo sapiens
75 HSPA1A 3303
Co-fractionation Homo sapiens
76 SORBS3 10174
Affinity Capture-MS Homo sapiens
77 PLP2 5355
Co-fractionation Homo sapiens
78 Nedd1  
Affinity Capture-MS Mus musculus
79 EIF2B1 1967
Affinity Capture-MS Homo sapiens
80 CSDE1 7812
Co-fractionation Homo sapiens
81 DLAT 1737
Co-fractionation Homo sapiens
82 PAIP1 10605
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
83 TLN2 83660
Affinity Capture-MS Homo sapiens
84 YBX1 4904
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
85 RPS27A 6233
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 GRB2 2885
Reconstituted Complex Homo sapiens
87 WDR77 79084
Affinity Capture-MS Homo sapiens
88 BAD  
Affinity Capture-MS Homo sapiens
89 MACF1 23499
Affinity Capture-MS Homo sapiens
90 USP1 7398
Affinity Capture-MS Homo sapiens
91 MTA1 9112
Affinity Capture-MS Homo sapiens
92 APOBEC3D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 LSM14A 26065
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
94 COX5A 9377
Affinity Capture-MS Homo sapiens
95 MORF4L2  
Co-fractionation Homo sapiens
96 PUF60 22827
Affinity Capture-MS Homo sapiens
97 MYH1  
Affinity Capture-MS Homo sapiens
98 ZEB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
100 WWP2 11060
Affinity Capture-MS Homo sapiens
101 MCM5 4174
Affinity Capture-MS Homo sapiens
102 GAPDH 2597
Co-fractionation Homo sapiens
103 HNRNPL 3191
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
104 SNRNP70 6625
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 RAD21 5885
Affinity Capture-Western Homo sapiens
106 SORT1 6272
Affinity Capture-MS Homo sapiens
107 CUL7 9820
Affinity Capture-MS Homo sapiens
108 ZNF169 169841
Affinity Capture-MS Homo sapiens
109 ANXA2 302
Co-fractionation Homo sapiens
110 SNRPA1 6627
Co-fractionation Homo sapiens
111 LUC7L 55692
Co-fractionation Homo sapiens
112 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
113 RBMXL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 NCBP1 4686
Co-fractionation Homo sapiens
115 SPRTN  
Affinity Capture-MS Homo sapiens
116 HSPA6 3310
Co-fractionation Homo sapiens
117 CCDC59  
Affinity Capture-MS Homo sapiens
118 USP13  
Affinity Capture-MS Homo sapiens
119 KCTD10 83892
Affinity Capture-MS Homo sapiens
120 GTF2IRD1  
Affinity Capture-MS Homo sapiens
121 TARDBP 23435
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
122 RPA2 6118
Affinity Capture-MS Homo sapiens
123 QKI 9444
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 ELAVL4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 NDUFB5 4711
Affinity Capture-MS Homo sapiens
126 PTTG1  
Affinity Capture-MS Homo sapiens
127 HSP90AB1 3326
Co-fractionation Homo sapiens
128 MRPL50 54534
Affinity Capture-MS Homo sapiens
129 CAND1 55832
Affinity Capture-MS Homo sapiens
130 SNRPF 6636
Affinity Capture-MS Homo sapiens
131 RPS3 6188
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
132 LGALS3BP 3959
Co-fractionation Homo sapiens
133 B3GNT2 10678
Affinity Capture-MS Homo sapiens
134 DDX24 57062
Affinity Capture-MS Homo sapiens
135 COPS6 10980
Affinity Capture-MS Homo sapiens
136 TLN1 7094
Affinity Capture-MS Homo sapiens
137 DUSP11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 PRC1 9055
Affinity Capture-MS Homo sapiens
139 SRRM2 23524
Co-fractionation Homo sapiens
140 KHDRBS1 10657
Co-fractionation Homo sapiens
141 OBSL1 23363
Affinity Capture-MS Homo sapiens
142 PLCG1 5335
Reconstituted Complex Homo sapiens
143 MALSU1  
Affinity Capture-MS Homo sapiens
144 NR4A1  
Affinity Capture-MS Homo sapiens
145 U2AF1 7307
Co-fractionation Homo sapiens
146 VCAM1 7412
Affinity Capture-MS Homo sapiens
147 DDX6 1656
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
148 CUL1 8454
Affinity Capture-MS Homo sapiens
149 TIMM50 92609
Co-fractionation Homo sapiens
150 RBM42  
Affinity Capture-MS Homo sapiens
151 SYT9 143425
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
152 PLCB3 5331
Affinity Capture-MS Homo sapiens
153 ICE2  
Affinity Capture-MS Homo sapiens
154 GAR1 54433
Affinity Capture-MS Homo sapiens
155 ATXN2 6311
Co-fractionation Homo sapiens
156 HMGXB4 10042
Affinity Capture-MS Homo sapiens
157 SYT2  
Reconstituted Complex Homo sapiens
158 C6orf203  
Proximity Label-MS Homo sapiens
159 HNRNPA0 10949
Co-fractionation Homo sapiens
160 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
161 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
162 RBM28 55131
Affinity Capture-MS Homo sapiens
163 NHS 4810
Affinity Capture-MS Homo sapiens
164 RECQL 5965
Affinity Capture-MS Homo sapiens
165 VRK1 7443
Affinity Capture-MS Homo sapiens
166 INTS7  
Affinity Capture-MS Homo sapiens
167 NCL 4691
Co-fractionation Homo sapiens
168 LUC7L2 51631
Co-fractionation Homo sapiens
169 IARS 3376
Co-fractionation Homo sapiens
170 TXNL4A 10907
Affinity Capture-MS Homo sapiens
171 DDX27 55661
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 HBA1 3039
Affinity Capture-MS Homo sapiens
173 PTGR2 145482
Affinity Capture-MS Homo sapiens
174 RPLP0 6175
Co-fractionation Homo sapiens
175 HNRNPD 3184
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
176 PTPN11 5781
Two-hybrid Homo sapiens
177 PER2  
Proximity Label-MS Homo sapiens
178 DHX36 170506
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
179 RC3H2  
Affinity Capture-MS Homo sapiens
180 IKZF3  
Affinity Capture-MS Homo sapiens
181 MTIF3  
Proximity Label-MS Homo sapiens
182 UBE2L6 9246
Affinity Capture-MS Homo sapiens
183 FUS 2521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
184 KIAA1524 57650
Two-hybrid Homo sapiens
185 ANKRD11 29123
Affinity Capture-MS Homo sapiens
186 MORF4L1  
Co-fractionation Homo sapiens
187 PCDH7 5099
Affinity Capture-MS Homo sapiens
188 CDK2 1017
Affinity Capture-MS Homo sapiens
189 MYC  
Affinity Capture-MS Homo sapiens
190 BAG1 573
Affinity Capture-MS Homo sapiens
191 CEBPZ  
Affinity Capture-MS Homo sapiens
192 BLMH 642
Affinity Capture-MS Homo sapiens
193 SCO1  
Affinity Capture-MS Homo sapiens
194 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
195 SNW1 22938
Affinity Capture-MS Homo sapiens
196 Junb  
Affinity Capture-MS Mus musculus
197 DDRGK1 65992
Affinity Capture-MS Homo sapiens
198 IKZF1  
Affinity Capture-MS Homo sapiens
199 APOBEC1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
200 NDUFV2 4729
Co-fractionation Homo sapiens
201 NKAP 79576
Affinity Capture-MS Homo sapiens
202 KIF21B 23046
Affinity Capture-MS Homo sapiens
203 STK24 8428
Affinity Capture-MS Homo sapiens
204 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
205 PARP1 142
Proximity Label-MS Homo sapiens
206 ILF3 3609
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
207 TP53 7157
Affinity Capture-MS Homo sapiens
208 PDCL 5082
Affinity Capture-MS Homo sapiens
209 TCIRG1 10312
Affinity Capture-MS Homo sapiens
210 KNOP1 400506
Affinity Capture-MS Homo sapiens
211 PPIL3 53938
Affinity Capture-MS Homo sapiens
212 NOP10 55505
Affinity Capture-MS Homo sapiens
213 HNRNPK 3190
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
214 ESR1  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
215 KHDRBS2  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
216 IL7R  
Protein-RNA Homo sapiens
217 DDX42 11325
Co-fractionation Homo sapiens
218 KRAS 3845
Affinity Capture-MS Homo sapiens
219 PHC2  
Affinity Capture-MS Homo sapiens
220 PRMT1 3276
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
221 RALY 22913
Co-fractionation Homo sapiens
222 GCFC2  
Affinity Capture-MS Homo sapiens
223 UBE2H 7328
Affinity Capture-MS Homo sapiens
224 HNRNPC 3183
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 RPL26L1 51121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 KHDRBS3  
Co-fractionation Homo sapiens
227 RAB1A 5861
Co-fractionation Homo sapiens
228 DNAJC8 22826
Affinity Capture-MS Homo sapiens
229 PTMA 5757
Affinity Capture-MS Homo sapiens
230 MRPL30  
Affinity Capture-MS Homo sapiens
231 ANGEL2 90806
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
232 DNAJA4 55466
Affinity Capture-MS Homo sapiens
233 PAK2 5062
Co-fractionation Homo sapiens
234 GAPDHS 26330
Affinity Capture-MS Homo sapiens
235 HNRNPR 10236
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
236 RET 5979
Affinity Capture-MS Homo sapiens
237 PI4KA 5297
Affinity Capture-MS Homo sapiens
238 HNRNPUL2 221092
Affinity Capture-MS Homo sapiens
239 CAPZB 832
Affinity Capture-MS Homo sapiens
240 SBF2 81846
Affinity Capture-MS Homo sapiens
241 ACAD9 28976
Proximity Label-MS Homo sapiens
242 MCM2 4171
Affinity Capture-MS Homo sapiens
243 CCDC137  
Affinity Capture-MS Homo sapiens
244 TRMT112 51504
Affinity Capture-MS Homo sapiens
245 IQGAP1 8826
Co-fractionation Homo sapiens
246 EWSR1 2130
Affinity Capture-MS Homo sapiens
247 SF3A2 8175
Affinity Capture-MS Homo sapiens
248 ITGA4 3676
Affinity Capture-MS Homo sapiens
249 UFSP2 55325
Affinity Capture-MS Homo sapiens
250 RPS3A 6189
Co-fractionation Homo sapiens
251 TFCP2 7024
Affinity Capture-MS Homo sapiens
252 CYLD  
Affinity Capture-MS Homo sapiens
253 PABPC4 8761
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
254 MTERF3  
Proximity Label-MS Homo sapiens
255 ZNF286A  
Affinity Capture-MS Homo sapiens
256 HSPA8 3312
Co-fractionation Homo sapiens
257 MDH2 4191
Proximity Label-MS Homo sapiens
258 NELFB 25920
Co-fractionation Homo sapiens
259 YTHDF1 54915
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
260 CUL4B 8450
Affinity Capture-MS Homo sapiens
261 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 PPIL1 51645
Affinity Capture-MS Homo sapiens
263 CENPV 201161
Affinity Capture-MS Homo sapiens
264 CLNS1A 1207
Affinity Capture-MS Homo sapiens
265 XRN1 54464
Co-fractionation Homo sapiens
266 DOT1L 84444
Affinity Capture-MS Homo sapiens
267 YPEL5 51646
Affinity Capture-MS Homo sapiens
268 NOP2 4839
Affinity Capture-MS Homo sapiens
269 MAPT  
Affinity Capture-MS Homo sapiens
270 NUPR1  
Two-hybrid Homo sapiens
271 CHMP4B 128866
Affinity Capture-MS Homo sapiens
272 BTF3 689
Affinity Capture-MS Homo sapiens
273 SYT3  
Reconstituted Complex Homo sapiens
274 NTRK1 4914
Affinity Capture-MS Homo sapiens
275 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
276 NSRP1  
Co-fractionation Homo sapiens
277 RPA4  
Proximity Label-MS Homo sapiens
278 RPN1 6184
Co-fractionation Homo sapiens
279 SYT8  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
280 DHX9 1660
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
281 PLXNA3 55558
Affinity Capture-MS Homo sapiens
282 PSMD2 5708
Affinity Capture-MS Homo sapiens
283 HNRNPA3 220988
Co-fractionation Homo sapiens
284 ACSL4 2182
Cross-Linking-MS (XL-MS) Homo sapiens
285 PAICS 10606
Co-fractionation Homo sapiens
286 RBM10  
Affinity Capture-MS Homo sapiens
287 HNRNPDL 9987
Co-fractionation Homo sapiens
288 HABP4  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
289 UBE2S  
Co-fractionation Homo sapiens
290 ZBTB2 57621
Affinity Capture-MS Homo sapiens
291 THUMPD1 55623
Co-fractionation Homo sapiens
292 METTL14  
Affinity Capture-MS Homo sapiens
293 CPEB1  
Affinity Capture-MS Homo sapiens
294 ECT2 1894
Affinity Capture-MS Homo sapiens
295 YTHDC2 64848
Affinity Capture-MS Homo sapiens
296 ZC3H8  
Affinity Capture-MS Homo sapiens
297 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
298 HNRNPUL1 11100
Affinity Capture-MS Homo sapiens
299 NCBP2 22916
Co-fractionation Homo sapiens
300 MRPS28  
Co-fractionation Homo sapiens
301 PRR3  
Affinity Capture-MS Homo sapiens
302 PSPC1 55269
Affinity Capture-MS Homo sapiens
303 A1CF  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
304 MTOR 2475
Affinity Capture-MS Homo sapiens
305 TP63  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
306 TOP1 7150
Affinity Capture-MS Homo sapiens
307 NHP2L1 4809
Co-fractionation Homo sapiens
308 ACTB 60
Co-fractionation Homo sapiens
309 HDLBP 3069
Affinity Capture-MS Homo sapiens
310 RNF2  
Affinity Capture-MS Homo sapiens
311 HSPD1 3329
Co-fractionation Homo sapiens
312 CSF2 1437
Affinity Capture-RNA Homo sapiens
313 METTL15  
Proximity Label-MS Homo sapiens
314 RBMS2 5939
Co-fractionation Homo sapiens
315 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
316 FBXW11  
Affinity Capture-MS Homo sapiens
317 MAP1S 55201
Co-fractionation Homo sapiens
318 RPS21 6227
Co-fractionation Homo sapiens
319 ICT1 3396
Co-fractionation Homo sapiens
320 DDX3X 1654
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
321 RPA1 6117
Affinity Capture-MS Homo sapiens
322 SNRPA 6626
Affinity Capture-MS Homo sapiens
323 HNRNPM 4670
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
324 TUBB3 10381
Affinity Capture-MS Homo sapiens
325 NHLRC2 374354
Affinity Capture-MS Homo sapiens
326 INSR 3643
Biochemical Activity Homo sapiens
327 MKI67  
Affinity Capture-MS Homo sapiens
328 MYL12A 10627
Co-fractionation Homo sapiens
329 UFL1 23376
Affinity Capture-MS Homo sapiens
330 UVSSA  
Affinity Capture-MS Homo sapiens
331 RPL23A 6147
Co-fractionation Homo sapiens
332 METTL3  
Affinity Capture-MS Homo sapiens
333 C14orf166 51637
Co-fractionation Homo sapiens
334 RPS27L 51065
Co-fractionation Homo sapiens
335 SERBP1 26135
Proximity Label-MS Homo sapiens
336 STT3B 201595
Co-fractionation Homo sapiens
337 RC3H1 149041
Affinity Capture-MS Homo sapiens
338 SSRP1 6749
Affinity Capture-MS Homo sapiens
339 HARS 3035
Co-fractionation Homo sapiens
340 SYT1 6857
Reconstituted Complex Homo sapiens
341 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
342 RPSA 3921
Co-fractionation Homo sapiens
343 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
344 CNBP 7555
Affinity Capture-MS Homo sapiens
345 SNAP23 8773
Co-fractionation Homo sapiens
346 PPIE 10450
Affinity Capture-MS Homo sapiens
347 RACGAP1 29127
Affinity Capture-MS Homo sapiens
348 Ybx1 22608
Affinity Capture-MS Mus musculus
349 TSNAX 7257
Affinity Capture-MS Homo sapiens
350 RPL10 6134
Co-fractionation Homo sapiens
351 LSM4 25804
Co-fractionation Homo sapiens
352 BASP1 10409
Co-fractionation Homo sapiens
353 TRIM55  
Two-hybrid Homo sapiens
354 RPUSD4 84881
Co-fractionation Homo sapiens
355 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
356 ILF2 3608
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
357 KIAA1429 25962
Affinity Capture-MS Homo sapiens
358 TROVE2 6738
Co-fractionation Homo sapiens
359 RPS20 6224
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
360 ARHGAP32  
Affinity Capture-MS Homo sapiens
361 CEMIP 57214
Affinity Capture-MS Homo sapiens
362 CKMT1A 548596
Cross-Linking-MS (XL-MS) Homo sapiens
363 COPS5 10987
Affinity Capture-MS Homo sapiens
364 FBXW7  
Affinity Capture-MS Homo sapiens
365 RPL24 6152
Co-fractionation Homo sapiens
366 MRPS24 64951
Affinity Capture-MS Homo sapiens
367 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
368 FBXO18 84893
Affinity Capture-MS Homo sapiens
369 MRPS26 64949
Proximity Label-MS Homo sapiens
370 PRKRA 8575
Affinity Capture-MS Homo sapiens
371 EED  
Affinity Capture-MS Homo sapiens
372 SETD1B 23067
Affinity Capture-MS Homo sapiens
373 SLC25A25  
Affinity Capture-MS Homo sapiens
374 MYCN  
Affinity Capture-MS Homo sapiens
375 FAM20C 56975
Affinity Capture-MS Homo sapiens
376 METTL13 51603
Co-fractionation Homo sapiens
377 STOML2 30968
Co-fractionation Homo sapiens
378 PPP1CA 5499
Co-fractionation Homo sapiens
379 IKBIP 121457
Co-fractionation Homo sapiens
380 RB1CC1 9821
Affinity Capture-MS Homo sapiens
381 SRA1 10011
Co-fractionation Homo sapiens
382 STAU1 6780
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
383 PTCD3 55037
Co-fractionation Homo sapiens
384 GRAMD4 23151
Affinity Capture-MS Homo sapiens
385 VCP 7415
Affinity Capture-MS Homo sapiens
386 DDX5 1655
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
387 LEMD2 221496
Affinity Capture-MS Homo sapiens
388 IFI16 3428
Affinity Capture-MS Homo sapiens
389 DICER1  
Affinity Capture-MS Homo sapiens
390 DDX54 79039
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
391 GNA13 10672
Affinity Capture-MS Homo sapiens
392 PABPN1 8106
Co-fractionation Homo sapiens
393 CDK9 1025
Affinity Capture-MS Homo sapiens
394 CEBPA  
Protein-peptide Homo sapiens
395 USP32 84669
Affinity Capture-MS Homo sapiens
396 ELAVL2 1993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
397 PHB 5245
Co-fractionation Homo sapiens
398 SFPQ 6421
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
399 GOLGA3 2802
Affinity Capture-MS Homo sapiens
400 TAF15 8148
Co-fractionation Homo sapiens
401 MRRF  
Proximity Label-MS Homo sapiens
402 FANCD2  
Affinity Capture-MS Homo sapiens
403 UPF1 5976
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
404 LETM1 3954
Co-fractionation Homo sapiens
405 SNRPB 6628
Affinity Capture-MS Homo sapiens
406 MYPOP  
Two-hybrid Homo sapiens
407 NAT10 55226
Affinity Capture-MS Homo sapiens
408 CTNNB1 1499
Affinity Capture-MS Homo sapiens
409 SRSF1 6426
Co-fractionation Homo sapiens
410 RPS6 6194
Co-fractionation Homo sapiens
411 CTTN 2017
Affinity Capture-MS Homo sapiens
412 GAA 2548
Co-fractionation Homo sapiens
413 UACA 55075
Affinity Capture-MS Homo sapiens
414 PSMD7 5713
Co-fractionation Homo sapiens
415 ECHS1 1892
Affinity Capture-MS Homo sapiens
416 APTX  
Affinity Capture-MS Homo sapiens
417 SF3A1 10291
Affinity Capture-MS Homo sapiens
418 AURKB 9212
Affinity Capture-MS Homo sapiens
419 EIF4H 7458
Co-fractionation Homo sapiens
420 C2CD5 9847
Affinity Capture-MS Homo sapiens
421 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
422 DKC1 1736
Affinity Capture-MS Homo sapiens
423 FBXO6 26270
Affinity Capture-MS Homo sapiens
424 HIST1H2BA 255626
Cross-Linking-MS (XL-MS) Homo sapiens
425 MAP3K4 4216
Affinity Capture-MS Homo sapiens
426 FNDC3A 22862
Affinity Capture-MS Homo sapiens
427 SF3B3 23450
Co-fractionation Homo sapiens
428 VDAC1 7416
Cross-Linking-MS (XL-MS) Homo sapiens
429 SYT7  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
430 BMP4 652
Affinity Capture-MS Homo sapiens
431 GNB2L1 10399
Co-fractionation Homo sapiens
432 CCDC8  
Affinity Capture-MS Homo sapiens
433 H2AFX 3014
Affinity Capture-MS Homo sapiens
434 RRP15  
Affinity Capture-MS Homo sapiens
435 DHX15 1665
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
436 FN1 2335
Affinity Capture-MS Homo sapiens
437 SIRT6  
Affinity Capture-MS Homo sapiens
438 FKBP3 2287
Co-fractionation Homo sapiens
439 ZRANB2 9406
Affinity Capture-MS Homo sapiens
440 CPSF6 11052
Affinity Capture-MS Homo sapiens
441 PNPLA8 50640
Affinity Capture-MS Homo sapiens
442 ZNF746  
Affinity Capture-MS Homo sapiens
443 CUL5 8065
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
444 ABCA7 10347
Affinity Capture-MS Homo sapiens
445 SMURF1 57154
Affinity Capture-MS Homo sapiens
446 ELAVL1 1994
Co-fractionation Homo sapiens
447 EPB41L2 2037
Co-fractionation Homo sapiens
448 TXN 7295
Co-fractionation Homo sapiens
449 IPO4 79711
Affinity Capture-MS Homo sapiens
450 TRIP4 9325
Affinity Capture-MS Homo sapiens
451 HSF1  
Co-fractionation Homo sapiens
452 TRIM31  
Affinity Capture-MS Homo sapiens
453 PINK1  
Affinity Capture-MS Homo sapiens
454 BIN3 55909
Affinity Capture-MS Homo sapiens
455 GRSF1 2926
Proximity Label-MS Homo sapiens
456 HNRNPU 3192
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
457 C9orf72  
Affinity Capture-MS Homo sapiens
458 METTL17  
Proximity Label-MS Homo sapiens
459 NEDD8 4738
Affinity Capture-MS Homo sapiens
460 CNDP2 55748
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which SYNCRIP is involved
No pathways found





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