Gene description for MAPKAP1
Gene name
mitogen-activated protein kinase associated protein 1
Gene symbol
MAPKAP1
Other names/aliases
JC310 MIP1 SIN1 SIN1b SIN1g
Species
Homo sapiens
Database cross references - MAPKAP1
ExoCarta
ExoCarta_79109
Entrez Gene
79109
HGNC
18752
MIM
610558
UniProt
Q9BPZ7
MAPKAP1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocellular carcinoma cells
26054723
Gene ontology annotations for MAPKAP1
Experiment description of studies that identified MAPKAP1 in exosomes
1
Experiment ID
235
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
236
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
✘
EV Membrane markers
✔
HSP90B1
EV Negative markers
✔
qNano
EV Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
Protein-protein interactions for MAPKAP1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SFN
2810
Affinity Capture-MS
Homo sapiens
2
RPTOR
57521
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
AKT1
207
Affinity Capture-Western
Homo sapiens
4
MTOR
2475
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
5
RICTOR
253260
Affinity Capture-MS
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-MS
Homo sapiens
6
CDC42EP1
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which MAPKAP1 is involved